Diastereo- and enantioselective hydrogenation of α-amino-β-keto ester hydrochlorides catalyzed by an iridium complex with MeO-BIPHEP and NaBArF: Catalytic cycle and five-membered chelation mechanism of asymmetric hydrogenation

Chemistry - A European Journal

Volumn 16, Issue 39, 2010, Pages 11954-11962

  Maeda, Tsukuru ^a   Makino, Kazuishi ^a   Iwasaki, Masamichi ^a   Hamada, Yasumasa ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

amino acids; asymmetric hydrogenation; dynamic kinetic resolution; iridium; reaction mechanisms

Indexed keywords

AMINE FUNCTIONS; AMINO ACID ESTERS; ASYMMETRIC HYDROGENATION; CATALYTIC CYCLES; DYNAMIC KINETIC RESOLUTION; ENANTIOSELECTIVE; ENANTIOSELECTIVE HYDROGENATION; HYDROGEN ATOMS; HYDROGEN PRESSURES; IRIDIUM COMPLEX; KETO ESTER; LOW HYDROGEN PRESSURE; MECHANISTIC STUDIES; REACTION MECHANISM; TRANSITION STATE;

AMINO ACIDS; CATALYSIS; CHELATION; DYNAMICS; ESTERIFICATION; ESTERS; HYDROGEN; IRIDIUM; IRIDIUM COMPOUNDS; KETONES; OXYGEN; REACTION RATES;

HYDROGENATION;

AMINO ACID; CHLORINATED HYDROCARBON; ESTER; IRIDIUM;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HYDROGENATION; KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; SYNTHESIS;

AMINO ACIDS; CATALYSIS; ESTERS; HYDROCARBONS, CHLORINATED; HYDROGENATION; IRIDIUM; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 78249287515     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201001298     Document Type: Article

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