Unravelling the mechanism and significance of thrombin binding to platelet glycoprotein Ib

Thrombosis and Haemostasis

Volumn 104, Issue 5, 2010, Pages 894-902

  Ruggeri, Zaverio M ^a   Zarpellon, Alessandro ^a   Roberts, James R ^a   Mc Clintock, Richard A ^a   Jing, Hua ^a   Mendolicchio, G Loredana ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

Animal models; GPIb; Thrombin; Thrombosis; Von Willebrand factor

Indexed keywords

GLYCOPROTEIN IB; MEMBRANE PROTEIN; THROMBIN;

AMINO TERMINAL SEQUENCE; BLOOD VESSEL INJURY; CONFERENCE PAPER; CRYSTAL STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; THROMBOCYTE MEMBRANE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HEMOSTASIS; HISTORY, 20TH CENTURY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; THROMBOSIS; VON WILLEBRAND FACTOR;

EID: 78149478342     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-09-0578     Document Type: Conference Paper

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