A nonhuman primate model of Alzheimer's disease generated by intracranial injection of amyloid-beta42 and thiorphan

Metabolic Brain Disease

Volumn 25, Issue 3, 2010, Pages 277-284

  Li, Wende ^a   Wu, Yu'E ^b   Min, Fangui ^a   Li, Zhuo ^a   Huang, Jiayuan ^a   Huang, Ren ^b  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b Guangdong Laboratory Animals Monitoring Institute   (China)

Author keywords

Alzheimer's disease (AD); Amyloid beta (A ) peptide; Choline acetyltransferase (ChAT); Glial fibrillary acidic protein (GFAP); Primate model; Thiorphan

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CHOLINE ACETYLTRANSFERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MEMBRANE METALLOENDOPEPTIDASE; THIORPHAN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BASAL GANGLION; BRAIN ATROPHY; BRAIN CORTEX; BRAIN NERVE CELL; CELL LOSS; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN LOCALIZATION; RHESUS MONKEY; WORKING MEMORY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CRANIOTOMY; DISEASE MODELS, ANIMAL; INFUSION PUMPS; MACACA MULATTA; MALE; NEPRILYSIN; NERVE DEGENERATION; PEPTIDE FRAGMENTS; PROTEASE INHIBITORS; THIORPHAN;

MACACA MULATTA; PRIMATES;

EID: 78149406228     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-010-9207-9     Document Type: Article

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