Quantitative proteomic analysis reveals the perturbation of multiple cellular pathways in Jurkat-T cells induced by doxorubicin

Journal of Proteome Research

Volumn 9, Issue 11, 2010, Pages 5943-5951

  Dong, Xiaoli ^a   Xiong, Lei ^a   Jiang, Xinning ^b   Wang, Yinsheng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

acute lymphoblastic leukemia; cholesterol biosynthesis; Doxorubicin; mass spectrometry; quantitative proteomics; SILAC

Indexed keywords

AMINO ACID; CHOLESTEROL; DOXORUBICIN; GERANYLTRANSFERASE; HISTONE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; RIBONUCLEOPROTEIN; SUPEROXIDE DISMUTASE;

ARTICLE; CELL CULTURE; CELL GROWTH; CHEMOTHERAPY; CHOLESTEROL SYNTHESIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CYTOTOXICITY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; GROWTH INHIBITION; HUMAN; HUMAN CELL; INTROSPECTION; ISOTOPE LABELING; LEUKEMIA CELL LINE; MASS SPECTROMETRY; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; UPREGULATION;

CELL PROLIFERATION; CHOLESTEROL; DOXORUBICIN; GENE EXPRESSION REGULATION; HUMANS; JURKAT CELLS; METABOLIC NETWORKS AND PATHWAYS; PROTEOMICS; T-LYMPHOCYTES;

EID: 78149373866     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr1007043     Document Type: Article

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