Dyslipidemia induces opposing effects on intrapulmonary and extrapulmonary host defense through divergent TLR response phenotypes

Journal of Immunology

Volumn 185, Issue 3, 2010, Pages 1660-1669

  Madenspacher, Jennifer H ^a   Draper, David W ^a   Smoak, Kathleen A ^a   Li, Haitao ^b   Griffiths, Gary L ^b   Suratt, Benjamin T ^c   Wilson, Martha D ^d   Rudel, Lawrence L ^d   Fessler, Michael B ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHOLESTEROL; CYTOKINE; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOODSTREAM INFECTION; CELL MIGRATION; CERAMIC PROSTHESIS; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE RESPONSE; DYSLIPIDEMIA; FEMALE; HOST RESISTANCE; INNATE IMMUNITY; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; LIPID RAFT; LUNG CLEARANCE; MACROPHAGE; MOUSE; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; PERITONEUM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BACTERIAL PNEUMONIA; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL CULTURE; CELL LINE; COMPARATIVE STUDY; IMMUNOLOGY; IMMUNOPHENOTYPING; KLEBSIELLA INFECTION; LUNG ALVEOLUS MACROPHAGE; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PERITONEUM MACROPHAGE;

ANIMALS; CELL LINE; CELLS, CULTURED; CYTOKINES; DYSLIPIDEMIAS; FEMALE; IMMUNITY, INNATE; IMMUNOPHENOTYPING; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MACROPHAGES, ALVEOLAR; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; PNEUMONIA, BACTERIAL; TOLL-LIKE RECEPTORS;

EID: 77956396422     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903501     Document Type: Article

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