Alterations in microRNA expression patterns in liver diseases;Eltérések a májbetegségek mikro-RNS- expressziós mintázatában

Orvosi Hetilap

Volumn 151, Issue 45, 2010, Pages 1843-1853

  Lendvai, Gábor ^a   Kiss, András ^a   Kovalszky, Ilona ^b   Schaff, Zsuzsa ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b És MTA SE EKSZ Molekuláris Pathologiai Kutatócsoport   (Hungary)

Author keywords

acetaminophen; cirrhosis; downregulation; gene expression; hepatitis; hepatocellular carcinoma; microRNA; overexpression

Indexed keywords

BIOLOGICAL MARKER; INTERFERON; LIVER ENZYME; MICRORNA; PARACETAMOL;

ALCOHOL LIVER DISEASE; CARCINOGENESIS; CELL FUNCTION; DOWN REGULATION; DRUG INDUCED DISEASE; GENE EXPRESSION; HEPATITIS C VIRUS; HUMAN; LIVER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FIBROSIS; LIVER INJURY; NONALCOHOLIC FATTY LIVER; REVIEW; VIRUS REPLICATION;

CARCINOMA, HEPATOCELLULAR; DOWN-REGULATION; FATTY LIVER; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATITIS, VIRAL, HUMAN; HEPATOCYTES; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER DISEASES; LIVER DISEASES, ALCOHOLIC; LIVER NEOPLASMS; MICRORNAS; TUMOR MARKERS, BIOLOGICAL;

EID: 78149343164     PISSN: 00306002     EISSN: 17886120     Source Type: Journal    
DOI: 10.1556/OH.2010.28985     Document Type: Review

References (65)

1. Cho, W. C.: MicroRNAs: potential biomarkers for cancer diagnosis, prognosis and targets for therapy. Int. J. Biochem. Cell. Biol., 2010, 42, 1273-1281.
2. Schetter, A. J., Heegaard, N. H., Harris, C. C.: Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis, 2010, 31, 37-49.
3. Lu, J., Getz, G., Miska, E. A. És mtsai: MicroRNA expression profiles classify human cancers. Nature, 2005, 435, 834-838.
4. Cronin, M., Pho, M., Dutta, D. és mtsai: Measurement of gene expression in archival paraffin-embedded tissues: development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay. Am. J. Pathol., 2004, 164, 35-42.
5. Li, J., Smyth, P., Flavin, R. és mtsai: Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells. BMC Biotechnol., 2007, 7, 36.
6. Xi, Y., Nakajima, G., Gavin, E. és mtsai: Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples. RNA, 2007, 13, 1668-1674.
7. Zhang, B., Wang, Q., Pan, X.: MicroRNAs and their regulatory roles in animals and plants. J. Cell. Physiol., 2007, 210, 279-289.
8. Wang, K., Zhang, S., Marzolf, B. és mtsai: Circulating micro-RNAs, potential biomarkers for drug-induced liver injury. Proc. Natl. Acad. Sci. U. S. A., 2009, 106, 4402-4407.
9. Griffiths-Jones, S., Grocock, R. J., van Dongen, S. és mtsai: miR-Base: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res., 2006, 34, D140-144.
10. Carthew, R. W., Sontheimer, E. J.: Origins and mechanisms of miRNAs and siRNAs. Cell, 2009, 136, 642-655.
11. Liang, Y., Ridzon, D., Wong, L. és mtsa: Characterization of microRNA expression profiles in normal human tissues. BMC Genomics, 2007, 8, 166.
12. Li, Y., Tan, W., Neo, T. W. és mtsai: Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma. Cancer Sci., 2009, 100, 1234-1242.
13. Tömböl Z., Szabó P., Rácz K. és mtsai: Relevance of microRNA-s in neoplastic diseases. Orv. Hetil., 2007, 148, 1135-1141.
14. Zhang, B., Pan, X., Cobb, G. P. és mtsa: MicroRNAs as oncogenes and tumor suppressors. Dev. Biol., 2007, 302, 1-12.
15. Sethupathy, P., Megraw, M., Hatzigeorgiou, A. G.: A guide through present computational approaches for the identification of mammalian MicroRNA targets. Nat. Methods, 2006, 3, 881-886.
16. Yu, Z., Baserga, R., Chen, L. és mtsai: MicroRNA, cell cycle, and human breast cancer. Am. J. Pathol., 2010, 176, 1058-1064.
17. Bala, S., Marcos, M., Szabo, G.: Emerging role of microRNAs in liver diseases. World J. Gastroenterol., 2009, 5, 5633-5640.
18. Shenouda, S. K., Alahari, S. K.: MicroRNA function in cancer: oncogene or a tumor suppressor? Cancer Metastasis Rev., 2009, 28, 369-378.
19. Mattick, J. S., Makunin, I. V.: Small regulatory RNAs in mammals. Hum. Mol. Genet., 2005, 14, R121-132.
20. Hui, A. B., Shi, W., Boutros, P. C. és mtsai: Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab. Invest., 2009, 89, 597-606.
21. Chen, X. M.: MicroRNA signatures in liver diseases. World J. Gastroenterol., 2009, 5, 1665-1672.
22. Tzur, G., Israel, A., Levy, A. és mtsai: Comprehensive gene and microRNA expression profiling reveals a role for microRNAs in human liver development. PLoS One, 2009, 4, e7511.
23. Lagos-Quintana, M., Rauhut, R., Yalcin, A. és mtsai: Identification of tissue-specific microRNAs from mouse. Curr. Biol., 2002, 12, 735-739.
24. Chang, J., Nicolas, E., Marks, D. és mtsai: MiR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol., 2004, 1, 106-113.
25. Bai, S., Nasser, M. W., Wang, B. és mtsai: MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J. Biol. Chem., 2009, 284, 32015-32027.
26. Esau, C., Davis, S., Murray, S. F. és mtsai: MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell. Metab., 2006, 3, 87-98.
27. Jopling, C. L.: Regulation of hepatitis C virus by microRNA-122. Biochem. Soc. Trans., 2008, 36, 1220-1223.
28. Fukushima, T., Hamada, Y., Yamada, H. és mtsa: Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride - regulating role of micro-RNA for RNA expression. J. Toxicol. Sci., 2007, 32, 401-409.
29. Musso, G., Gambino, R., Cassader, M.: Emerging molecular targets for the treatment of nonalcoholic fatty liver disease. Annu. Rev. Med., 2010, 61, 375-392.
30. Cheung, O., Puri, P., Eicken, C. és mtsai: Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology, 2008, 48, 1810-1820.
31. Jin, X., Ye, Y. F., Chen, S. H. és mtsai: MicroRNA expression pattern in different stages of nonalcoholic fatty liver disease. Dig. Liver Dis., 2009, 41, 289-297.
32. Dolganiuc, A., Petrasek, J., Kodys, K. és mtsai: MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice. Alcohol. Clin. Exp. Res., 2009 33, 1704-1710.
33. Tang, Y., Banan, A., Forsyth, C. B. és mtsai: Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease. Alcohol. Clin. Exp. Res., 2008, 32, 355-364.
34. Venugopal, S. K., Jiang, J., Kim, T. H és mtsai: Liver fibrosis causes down-regulation of miRNA-150 and miRNA-194 in hepatic stellate cells and their over-expression causes decreased stellate cell activation. Am. J. Physiol. Gastrointest. Liver Physiol., 2010, 298, 101-106.
35. Ji, J., Zhang, J., Huang, G. és mtsai: Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett., 2009, 583, 759-766.
36. Guo, C. J., Pan, Q., Cheng, T. és mtsai: Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways. FEBS J., 2009, 276, 5163-5176.
37. Ura, S., Honda, M., Yamashita, T. és mtsai: Differential micro-RNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma. Hepatology, 2009, 49, 1098-1112.
38. Henke, J. I., Goergen, D., Zheng, J. és mtsai: MicroRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J., 2008, 27, 3300-3310.
39. Sarasin-Filipowicz, M., Krol, J., Markiewicz, I. és mtsai: Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat. Med., 2009, 15, 31-33.
40. Lanford, R. E., Hildebrandt-Eriksen, E. S., Petri, A. és mtsai: Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science, 2010, 327, 198-201.
41. Pedersen, I. M., Cheng, G., Wieland, S. és mtsai: Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature, 2007, 449, 919-922. (Pubitemid 47598616)
42. Dienes, H. P., Scheffler, M., Schievenbusch, S. és mtsai: MicroRNA: New biomarkers in chronic liver disease. Global Antiviral Journal, 2009, 5, S1/63 Abstract 66.
43. Jiang, J., Gusev, Y., Aderca, I. és mtsai: Association of microRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. Clin. Cancer Res., 2008, 14, 419-427.
44. Huang, S., He, X., Ding, J. és mtsai: Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells. Int. J. Cancer, 2008, 123, 972-978.
45. Murakami, Y., Yasuda, T., Saigo, K. és mtsai: Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene, 2006, 25, 2537-2545.
46. Ladeiro, Y., Couchy, G., Balabaud, C. és mtsai: MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology, 2008, 47, 1955-1963.
47. Schaff Z., Kovalszky I., Lotz G. és mtsa: A hepatocellularis carcinoma - a makroszkópiától a molekuláris patológiáig. Orv. Hetil., 2010, 151, 982-989.
48. Pineau, P., Volinia, S., McJunkin, K. és mtsai: MiR-221 overexpression contributes to liver tumorigenesis. Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 264-269.
49. Gramantieri, L., Ferracin, M., Fornari, F. és mtsai: Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res., 2007, 67, 6092-6099.
50. Magrelli, A., Azzalin, G., Salvatore, M. és mtsai: Altered micro-RNA expression patterns in hepatoblastoma patients. Transl. Oncol., 2009, 2, 157-163.
51. Liu, W. H., Yeh, S. H., Lu, C. C. és mtsai: MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells. Gastroenterology, 2009, 136, 683-693.
52. Li, S., Fu, H., Wang, Y. és mtsai: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma. Hepatology, 2009, 49, 1194-1202.
53. Li, W., Xie, L., He, X. és mtsai: Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma. Int. J. Cancer, 2008, 123, 1616-1622.
54. Meng, F., Henson, R., Wehbe-Janek, H. és mtsai: MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology, 2007, 133, 647-658.
55. Su, H., Yang, J. R., Xu, T. és mtsai: MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res., 2009, 69, 1135-1142.
56. Wang, Y., Lee, A. T., Ma, J. Z. és mtsai: Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. J. Biol. Chem., 2008, 283, 13205-13215.
57. Varnholt, H., Drebber, U., Schulze, F. és mtsai: MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma. Hepatology, 2008, 47, 1223-1232.
58. Coulouarn, C., Factor, V. M., Andersen, J. B. és mtsai: Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene, 2009, 28, 3526-3536.
59. Budhu, A., Jia, H. L., Forgues, M. és mtsai: Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology, 2008, 47, 897-907.
60. Kutay, H., Bai, S., Datta, J. és mtsai: Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J. Cell. Biochem., 2006, 99, 671-678.
61. Li, N., Fu, H., Tie, Y. és mtsai: MiR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells. Cancer Lett., 2009, 275, 44-53.
62. Tsai, W. C., Hsu, P. W., Lai, T. C és mtsai: MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma. Hepatology, 2009, 49, 1571-1582.
63. Ji, J., Wang, X. W.: New kids on the block: diagnostic and prognostic microRNAs in hepatocellular carcinoma. Cancer Biol. Ther., 2009, 8, 1686-1693.
64. Laterza, O. F., Lim, L., Garrett-Engele, P. W. és mtsai: Plasma microRNAs as sensitive and specific biomarkers of tissue injury. Clin. Chem., 2009, 55, 1977-1983.
65. Girard, M., Jacquemin, E., Munnich, A. és mtsai: MiR-122, a paradigm for the role of microRNAs in the liver. J. Hepatol., 2008, 48, 648-656.