-
1
-
-
0032545933
-
-
Fire, A., Xu, S., Montgomery, M. K. és mtsai: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391, 806-811.
-
Fire, A., Xu, S., Montgomery, M. K. és mtsai: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391, 806-811.
-
-
-
-
2
-
-
0345490948
-
RNA interference in biology and medicine
-
Milhavet, O., Gary, D. S., Mattson, M. P.: RNA interference in biology and medicine. Pharmacol. Rev., 2003, 55, 629-648.
-
(2003)
Pharmacol. Rev
, vol.55
, pp. 629-648
-
-
Milhavet, O.1
Gary, D.S.2
Mattson, M.P.3
-
3
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism and function
-
Bartel, D. P.: MicroRNAs: genomics, biogenesis, mechanism and function. Cell, 2004, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
4
-
-
28044471565
-
MicroRNA functions in animal development and human disease
-
Alvarez-Garcia, I., Miska, E. A.: MicroRNA functions in animal development and human disease. Development, 2005, 132, 4653-4662.
-
(2005)
Development
, vol.132
, pp. 4653-4662
-
-
Alvarez-Garcia, I.1
Miska, E.A.2
-
5
-
-
33645500266
-
Progress towards in vivo use of siRNAs
-
Behlke, M. A.: Progress towards in vivo use of siRNAs. Mol. Ther., 2006, 13, 644-670.
-
(2006)
Mol. Ther
, vol.13
, pp. 644-670
-
-
Behlke, M.A.1
-
6
-
-
28644432079
-
RNA interference as a gene-specific approach for molecular medicine
-
Grünweller, A., Hartmann, R. K.: RNA interference as a gene-specific approach for molecular medicine. Curr. Med. Chem., 2005, 12, 3143-3161.
-
(2005)
Curr. Med. Chem
, vol.12
, pp. 3143-3161
-
-
Grünweller, A.1
Hartmann, R.K.2
-
7
-
-
33747102798
-
RNAI and MicroRNAs: From animal models to disease therapy
-
Fjose, A., Drivenes, O.: RNAI and MicroRNAs: from animal models to disease therapy. Birth Defects Res., 2006, 78, 150-171.
-
(2006)
Birth Defects Res
, vol.78
, pp. 150-171
-
-
Fjose, A.1
Drivenes, O.2
-
8
-
-
29644432901
-
MicroRNAs and endocrine biology
-
Cuellar, T. I., McManus, M. T.: MicroRNAs and endocrine biology. J. Endocrinol., 2005, 187, 327-332.
-
(2005)
J. Endocrinol
, vol.187
, pp. 327-332
-
-
Cuellar, T.I.1
McManus, M.T.2
-
9
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B. P., Burge, C. B., Bartel, D. P.: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 2005, 120, 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
10
-
-
24344494340
-
How microRNAs control cell division, differentiation and death?
-
Miska, E. A.: How microRNAs control cell division, differentiation and death? Curr. Opin. Gen. Dev., 2005, 15, 563-568.
-
(2005)
Curr. Opin. Gen. Dev
, vol.15
, pp. 563-568
-
-
Miska, E.A.1
-
11
-
-
14344257055
-
MicroRNAs as regulators of mammalian hematopoiesis
-
Chen, C. Z., Lodish, H. F.: MicroRNAs as regulators of mammalian hematopoiesis. Sem. Immunol., 2005, 17, 155-165.
-
(2005)
Sem. Immunol
, vol.17
, pp. 155-165
-
-
Chen, C.Z.1
Lodish, H.F.2
-
12
-
-
84873225180
-
-
Essau, C., Kang, X., Peralta, E. és mtsai: MicroRNA-143 regulates adipocyte differentiation. J. Biol. Chem., 2004, 279, 52631-52635.
-
Essau, C., Kang, X., Peralta, E. és mtsai: MicroRNA-143 regulates adipocyte differentiation. J. Biol. Chem., 2004, 279, 52631-52635.
-
-
-
-
13
-
-
9144270691
-
J. és mtsai: A pancreatic islet-specific microRNA regulates insulin secretion
-
Poy, M. N., Eliasson, I., Krutzfeldt, J. és mtsai: A pancreatic islet-specific microRNA regulates insulin secretion. Nature, 2004, 432, 226-230.
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.1
Eliasson, N.2
Krutzfeldt, I.3
-
14
-
-
2342420041
-
-
Pfeffer, S., Zavolan, M, Grässer, F. A. és mtsai: Identification of virus-encoded microRNAs. Science, 2004, 304, 734-736.
-
Pfeffer, S., Zavolan, M, Grässer, F. A. és mtsai: Identification of virus-encoded microRNAs. Science, 2004, 304, 734-736.
-
-
-
-
15
-
-
33645135862
-
Anti-miRNA oligonucleotides (AMOs): Ammunition to target miRNAs implicated in human disease?
-
Weiler, J., Hunziker, J., Hall, J.: Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? Gene Ther., 2006, 13, 496-502.
-
(2006)
Gene Ther
, vol.13
, pp. 496-502
-
-
Weiler, J.1
Hunziker, J.2
Hall, J.3
-
16
-
-
33644853907
-
J. és mtsai: The colorectal microRNAome
-
Cummins, J. M., He, Y., Leary, R. J. és mtsai: The colorectal microRNAome. Proc. Natl. Acad. Sci. USA, 2006, 103, 3687-3692.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3687-3692
-
-
Cummins, J.M.1
He, Y.2
Leary, R.3
-
17
-
-
9744252254
-
Genomics and proteomics: Expression arrays in clinical oncology
-
iv163-iv165
-
Fey, M. F.: Genomics and proteomics: expression arrays in clinical oncology. Ann. Oncol., 2004, 15 (Suppl. 4), iv163-iv165.
-
(2004)
Ann. Oncol
, vol.15
, Issue.SUPPL. 4
-
-
Fey, M.F.1
-
18
-
-
0038352264
-
Genetic advances will influence the practice of medicine: Examples from cancer research and care of cancer patients
-
Omenn, G. S.: Genetic advances will influence the practice of medicine: examples from cancer research and care of cancer patients. Genet. Med., 2002, 4 (Suppl. 6), 15S-20S.
-
(2002)
Genet. Med
, vol.4
, Issue.SUPPL. 6
-
-
Omenn, G.S.1
-
19
-
-
0034680102
-
-
Perou, C. M., Serlie, T., Elsen, M. B. és mtsai: Molecular portraits of human breast tumours. Nature, 2000, 406, 747-752.
-
Perou, C. M., Serlie, T., Elsen, M. B. és mtsai: Molecular portraits of human breast tumours. Nature, 2000, 406, 747-752.
-
-
-
-
20
-
-
20444460289
-
-
Lu, J., Getz, G., Miska, E. A. és mtsai: MicroRNA expression profiles classify human cancers. Nature, 2005, 435, 834-838.
-
Lu, J., Getz, G., Miska, E. A. és mtsai: MicroRNA expression profiles classify human cancers. Nature, 2005, 435, 834-838.
-
-
-
-
21
-
-
27244432205
-
MicroRNAs as oncogenes and tumor suppressors
-
Chen, C. Z.: MicroRNAs as oncogenes and tumor suppressors. N. Eng. J. Med., 2005, 353, 1768-1771.
-
(2005)
N. Eng. J. Med
, vol.353
, pp. 1768-1771
-
-
Chen, C.Z.1
-
22
-
-
12144290519
-
-
Calin, G. A., Sevignani, C., Dumitru, C. D. és mtsai: Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. USA, 2004, 101, 2999-3004.
-
Calin, G. A., Sevignani, C., Dumitru, C. D. és mtsai: Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. USA, 2004, 101, 2999-3004.
-
-
-
-
23
-
-
18744396337
-
-
Calin, G. A., Dumitru, C. D., Shimizu, M. és mtsai: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA, 2002, 99, 15524-15529.
-
Calin, G. A., Dumitru, C. D., Shimizu, M. és mtsai: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA, 2002, 99, 15524-15529.
-
-
-
-
24
-
-
27244434788
-
-
Calin, G. A., Ferracin, M., Cimmino, A. és mtsai: A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Eng. J. Med., 2005, 353, 1793-1801.
-
Calin, G. A., Ferracin, M., Cimmino, A. és mtsai: A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Eng. J. Med., 2005, 353, 1793-1801.
-
-
-
-
25
-
-
25444520537
-
-
Cimmino, A., Calin, G. A., Fabri, M. és mtsai: miR-15 and miR-16 induce apoptosis by targetinb BCL2. Proc. Natl. Acad. Sci USA, 2005, 102, 13944-13949.
-
Cimmino, A., Calin, G. A., Fabri, M. és mtsai: miR-15 and miR-16 induce apoptosis by targetinb BCL2. Proc. Natl. Acad. Sci USA, 2005, 102, 13944-13949.
-
-
-
-
26
-
-
4143142117
-
-
Calin, G. A., Liu, C. G., Sevignani, C. és mtsai: MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl. Acad. Sci. USA, 2004, 101, 11755-11760.
-
Calin, G. A., Liu, C. G., Sevignani, C. és mtsai: MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl. Acad. Sci. USA, 2004, 101, 11755-11760.
-
-
-
-
27
-
-
26044481464
-
-
Kluiver, J., Poppema, S., de Jong, D. és mtsai: BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. J. Pathol., 2005, 207, 243-249.
-
Kluiver, J., Poppema, S., de Jong, D. és mtsai: BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. J. Pathol., 2005, 207, 243-249.
-
-
-
-
28
-
-
0346727383
-
-
Metzler, M., Wilda, M., Busch, K. és mtsai: High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chrom. Cancer, 2004, 39, 167-169.
-
Metzler, M., Wilda, M., Busch, K. és mtsai: High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chrom. Cancer, 2004, 39, 167-169.
-
-
-
-
29
-
-
2542626605
-
-
Takamizawa, J., Konishi, H., Yanagisawa, K. és mtsai: Reduced expression of the let-6 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res., 2004, 64, 3753-3756.
-
Takamizawa, J., Konishi, H., Yanagisawa, K. és mtsai: Reduced expression of the let-6 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res., 2004, 64, 3753-3756.
-
-
-
-
30
-
-
0034597777
-
-
Pasquinelli, A. E., Reinhart, B. J., Slack, F. és mtsai: Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 2000, 408, 86-89.
-
Pasquinelli, A. E., Reinhart, B. J., Slack, F. és mtsai: Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 2000, 408, 86-89.
-
-
-
-
31
-
-
20044395613
-
J. és mtsai: RAS is regulated by the let-7 microRNA family
-
Johnson, S. M., Grosshans, H., Shingara, J. és mtsai: RAS is regulated by the let-7 microRNA family. Cell, 2005, 120, 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.1
Grosshans, M.2
Shingara, H.3
-
32
-
-
0142120587
-
-
Michael, M. Z., O'Connor, S. M., van Holst Pellekaan, N. G. és mtsai: Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol. Cancer Res., 2003, 1, 882-891.
-
Michael, M. Z., O'Connor, S. M., van Holst Pellekaan, N. G. és mtsai: Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol. Cancer Res., 2003, 1, 882-891.
-
-
-
-
33
-
-
33646157967
-
-
Murakami, Y., Yasuda, T., Saigo, K. és mtsai: Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene, 2006, 25, 2537-2545.
-
Murakami, Y., Yasuda, T., Saigo, K. és mtsai: Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene, 2006, 25, 2537-2545.
-
-
-
-
34
-
-
23844555119
-
-
Iorio, M. V., Ferracin, M., Liu, C. G. és mtsai: MicroRNA gene expression deregulation in human breast cancer. Cancer Res., 2005, 65, 7065-7070.
-
Iorio, M. V., Ferracin, M., Liu, C. G. és mtsai: MicroRNA gene expression deregulation in human breast cancer. Cancer Res., 2005, 65, 7065-7070.
-
-
-
-
35
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
Chan, J. A., Krichevsky, A. M., Kosik, K. S.: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 2005, 65, 6029-6033.
-
(2005)
Cancer Res
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
36
-
-
33750600178
-
-
Roldo, C., Missiaglia, E., Hagan, J. P. és mtsai: MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behaviour. J. Clin. Oncol., 2006, 24, 4677-4684.
-
Roldo, C., Missiaglia, E., Hagan, J. P. és mtsai: MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behaviour. J. Clin. Oncol., 2006, 24, 4677-4684.
-
-
-
-
37
-
-
33748752233
-
-
Weber, F., Teresi, R. E., Broelsch, C. E. és mtsai: A limited set of human microRNA is deregulated in follicular thyroid carcinoma. J. Clin. Endocrinol. Metab., 2006, 91, 3584-3591.
-
Weber, F., Teresi, R. E., Broelsch, C. E. és mtsai: A limited set of human microRNA is deregulated in follicular thyroid carcinoma. J. Clin. Endocrinol. Metab., 2006, 91, 3584-3591.
-
-
-
-
38
-
-
30044436911
-
-
He, H., Jazdrewski, K., Li, W. és mtsai: The role of microRNA genes in papillary thyroid carcinoma. Proc. Natl. Acad. Sci. USA, 2005, 102, 19075-19080.
-
He, H., Jazdrewski, K., Li, W. és mtsai: The role of microRNA genes in papillary thyroid carcinoma. Proc. Natl. Acad. Sci. USA, 2005, 102, 19075-19080.
-
-
-
-
39
-
-
0028911719
-
-
Natali, P. G., Berlingieri, M. T., Nicotra, M. R. és mtsai: Transformation of thyroid epithelium is associated with loss of c-kit receptor. Cancer Res., 1995, 55, 1787-1791.
-
Natali, P. G., Berlingieri, M. T., Nicotra, M. R. és mtsai: Transformation of thyroid epithelium is associated with loss of c-kit receptor. Cancer Res., 1995, 55, 1787-1791.
-
-
-
-
40
-
-
29144440077
-
-
Felli, N., Fontana, L., Pelosi, E. és mtsai: MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc. Natl. Acad. Sd. USA, 2005, 102, 18081-18086.
-
Felli, N., Fontana, L., Pelosi, E. és mtsai: MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc. Natl. Acad. Sd. USA, 2005, 102, 18081-18086.
-
-
-
-
41
-
-
33845608588
-
-
Bottoni, A., Zatelli, M. C., Ferracin, M. és mtsai: Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. J. Cell. Physiol., 2007, 210, 370-377.
-
Bottoni, A., Zatelli, M. C., Ferracin, M. és mtsai: Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. J. Cell. Physiol., 2007, 210, 370-377.
-
-
-
-
42
-
-
33144490646
-
-
Volinia, S., Calin, G. A., Liu, C. G. és mtsai: A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA, 2006, 103, 2257-2261.
-
Volinia, S., Calin, G. A., Liu, C. G. és mtsai: A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA, 2006, 103, 2257-2261.
-
-
-
-
43
-
-
0037197920
-
Disentangling the MYC web
-
Levens, D.: Disentangling the MYC web. Proc. Natl. Acad. Sci. USA, 2002, 99, 5757-5759.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5757-5759
-
-
Levens, D.1
-
44
-
-
20444479428
-
-
O'Donnell, K. A., Wentzel, E. A., Zeller, K. I. és mtsai: c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 2005, 435, 839-843.
-
O'Donnell, K. A., Wentzel, E. A., Zeller, K. I. és mtsai: c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 2005, 435, 839-843.
-
-
-
-
45
-
-
33746871416
-
Can siRNA technology provide the tools for gene therapy of the future?
-
Rácz, Z., Hamar P.: Can siRNA technology provide the tools for gene therapy of the future? Curr. Med. Chem., 2006, 13, 2299-2307.
-
(2006)
Curr. Med. Chem
, vol.13
, pp. 2299-2307
-
-
Rácz, Z.1
Hamar, P.2
-
46
-
-
33745625836
-
Therapeutical potential of RNA interference against cancer
-
Takeshita, F., Ochiya, T.: Therapeutical potential of RNA interference against cancer. Cancer Sci., 2006, 97, 689-696.
-
(2006)
Cancer Sci
, vol.97
, pp. 689-696
-
-
Takeshita, F.1
Ochiya, T.2
-
47
-
-
13844254514
-
Retroviral gene therapy: Safety issues and possible solutions
-
Yi, Y., Hahm, S. H., Lee, K. H.: Retroviral gene therapy: safety issues and possible solutions. Curr. Gene Ther., 2005, 5, 25-35.
-
(2005)
Curr. Gene Ther
, vol.5
, pp. 25-35
-
-
Yi, Y.1
Hahm, S.H.2
Lee, K.H.3
-
48
-
-
33748069824
-
siRNA and isRNA: Two edges of one sword
-
Schlee, M., Hornung, V., Hartmann, G.: siRNA and isRNA: two edges of one sword. Mol. Ther., 2006, 14, 463-470.
-
(2006)
Mol. Ther
, vol.14
, pp. 463-470
-
-
Schlee, M.1
Hornung, V.2
Hartmann, G.3
-
49
-
-
28444469246
-
-
Krützfeldt, J., Rajewsky, N., Braich, R. és mtsai: Silencing of microRNAs in vivo with 'antagomirs'. Nature, 2005, 438, 685-689.
-
Krützfeldt, J., Rajewsky, N., Braich, R. és mtsai: Silencing of microRNAs in vivo with 'antagomirs'. Nature, 2005, 438, 685-689.
-
-
-
-
50
-
-
23044449556
-
First clinical data on RNAi
-
Whelan, J. First clinical data on RNAi. Drug Discovery Today, 2005, 10, 1014-1015.
-
(2005)
Drug Discovery Today
, vol.10
, pp. 1014-1015
-
-
Whelan, J.1
|