메뉴 건너뛰기




Volumn 67, Issue 11, 1999, Pages 6008-6018

Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; LIPOPROTEIN; POLYPEPTIDE; SIGNAL PEPTIDE;

EID: 0032755494     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.11.6008-6018.1999     Document Type: Article
Times cited : (78)

References (44)
  • 1
    • 0032523936 scopus 로고    scopus 로고
    • A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state
    • Akins, D. R., K. W. Bourell, M. J. Caimano, M. V. Norgard, and J. D. Radolf. 1998. A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J. Clin. Investig. 101:2240-2250.
    • (1998) J. Clin. Investig. , vol.101 , pp. 2240-2250
    • Akins, D.R.1    Bourell, K.W.2    Caimano, M.J.3    Norgard, M.V.4    Radolf, J.D.5
  • 2
    • 0033020426 scopus 로고    scopus 로고
    • Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides
    • Akins, D. R., M. J. Caimano, X. Yang, F. Cerna, M. V. Norgard, and J. D. Radolf. 1999. Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides. Infect. Immun. 67:1526-1532.
    • (1999) Infect. Immun. , vol.67 , pp. 1526-1532
    • Akins, D.R.1    Caimano, M.J.2    Yang, X.3    Cerna, F.4    Norgard, M.V.5    Radolf, J.D.6
  • 3
    • 0029597816 scopus 로고
    • Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue
    • Akins, D. R., S. F. Porcella, T. G. Popova, D. Shevchenko, M. Li, M. V. Norgard, and J. D. Radolf. 1995. Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol. Microbiol. 18:507-520.
    • (1995) Mol. Microbiol. , vol.18 , pp. 507-520
    • Akins, D.R.1    Porcella, S.F.2    Popova, T.G.3    Shevchenko, D.4    Li, M.5    Norgard, M.V.6    Radolf, J.D.7
  • 4
    • 0030589698 scopus 로고    scopus 로고
    • Identification and mapping of a chromosomal gene cluster of Borrelia burgdorferi containing genes expressed in vivo
    • Aron, L., C. Toth, H. P. Godfrey, and F. C. Cabello. 1996. Identification and mapping of a chromosomal gene cluster of Borrelia burgdorferi containing genes expressed in vivo. FEMS Microbiol. Lett. 145:309-314.
    • (1996) FEMS Microbiol. Lett. , vol.145 , pp. 309-314
    • Aron, L.1    Toth, C.2    Godfrey, H.P.3    Cabello, F.C.4
  • 5
    • 0345059554 scopus 로고    scopus 로고
    • 7 July revision date. [Online.] The Institute for Genomic Research, Rockville, Md. [24 September 1999, last date accessed]
    • Borrelia burgdorferi Genome Database. 7 July 1999, revision date. [Online.] http://www.tigr.org/tdn/mdb/bbdb/bbdb.html. The Institute for Genomic Research, Rockville, Md. [24 September 1999, last date accessed].
    • (1999) Borrelia Burgdorferi Genome Database
  • 6
    • 0031012029 scopus 로고    scopus 로고
    • Homology throughout the multiple 32-kilobase circular plasmids present in Lyme disease spirochetes
    • Casjens, S., R. van Vugt, K. Tilly, P. A. Rosa, and B. Stevenson. 1997. Homology throughout the multiple 32-kilobase circular plasmids present in Lyme disease spirochetes. J. Bacteriol. 179:217-227.
    • (1997) J. Bacteriol. , vol.179 , pp. 217-227
    • Casjens, S.1    Van Vugt, R.2    Tilly, K.3    Rosa, P.A.4    Stevenson, B.5
  • 7
    • 0032435639 scopus 로고    scopus 로고
    • DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodies
    • Cassatt, D. R., N. K. Patel, N. D. Ulbrandt, and M. S. Hanson. 1998. DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodies. Infect. Immun. 66:5379-5387.
    • (1998) Infect. Immun. , vol.66 , pp. 5379-5387
    • Cassatt, D.R.1    Patel, N.K.2    Ulbrandt, N.D.3    Hanson, M.S.4
  • 8
    • 0031566340 scopus 로고    scopus 로고
    • Lyme disease - United States, 1996
    • Centers for Disease Control and Prevention. 1997. Lyme disease - United States, 1996. Morbid. Mortal. Weekly Rep. 46:531-535.
    • (1997) Morbid. Mortal. Weekly Rep. , vol.46 , pp. 531-535
  • 9
    • 0028335843 scopus 로고
    • A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: Evidence for expression only during infection
    • Champion, C. I., D. R. Blanco, J. T. Skare, D. A. Haake, M. Giladi, D. Foley, J. N. Miller, and M. A. Lovett. 1994. A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: evidence for expression only during infection. Infect. Immun. 62:2653-2661.
    • (1994) Infect. Immun. , vol.62 , pp. 2653-2661
    • Champion, C.I.1    Blanco, D.R.2    Skare, J.T.3    Haake, D.A.4    Giladi, M.5    Foley, D.6    Miller, J.N.7    Lovett, M.A.8
  • 12
    • 0029881189 scopus 로고    scopus 로고
    • Regulatory noise in prokaryotic promoters: How bacteria learn to respond to novel environmental signals
    • de Lorenzo, V., and J. Perez-Martin. 1996. Regulatory noise in prokaryotic promoters: how bacteria learn to respond to novel environmental signals. Mol. Microbiol. 19:1177-1184.
    • (1996) Mol. Microbiol. , vol.19 , pp. 1177-1184
    • De Lorenzo, V.1    Perez-Martin, J.2
  • 13
    • 0032950531 scopus 로고    scopus 로고
    • Influence of outer surface protein a antibody on Borrelia burgdorferi within feeding ticks
    • de Silva, A. M., N. S. Zeidner, Y. Zhang, M. C. Dolan, J. Piesman, and E. Fikrig. 1999. Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks. Infect. Immun. 67:30-35.
    • (1999) Infect. Immun. , vol.67 , pp. 30-35
    • De Silva, A.M.1    Zeidner, N.S.2    Zhang, Y.3    Dolan, M.C.4    Piesman, J.5    Fikrig, E.6
  • 14
    • 0030025949 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine
    • deSilva, A. M., S. R. Telford, L. R. Brunet, S. W. Barthold, and E. Fikrig. 1996. Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J. Exp. Med. 183:271-275.
    • (1996) J. Exp. Med. , vol.183 , pp. 271-275
    • DeSilva, A.M.1    Telford, S.R.2    Brunet, L.R.3    Barthold, S.W.4    Fikrig, E.5
  • 15
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereux, J., P. Haeberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereux, J.1    Haeberli, P.2    Smithies, O.3
  • 17
    • 0031662742 scopus 로고    scopus 로고
    • Differential expression of Borrelia burgdorferi genes during erythema migrans and Lyme arthritis
    • Fikrig, E., W. Feng, J. Aversa, R. T. Schoen, and R. A. Flavell. 1998. Differential expression of Borrelia burgdorferi genes during erythema migrans and Lyme arthritis. J. Infect. Dis. 178:1198-1201.
    • (1998) J. Infect. Dis. , vol.178 , pp. 1198-1201
    • Fikrig, E.1    Feng, W.2    Aversa, J.3    Schoen, R.T.4    Flavell, R.A.5
  • 19
    • 15644382120 scopus 로고    scopus 로고
    • A monoclonal antibody generated by antigen inoculation via tick bite is reactive to the Borrelia burgdorferi Rev protein, a member of the 2.9 gene family locus
    • Gilmore, R. D., and M. L. Mbow. 1998. A monoclonal antibody generated by antigen inoculation via tick bite is reactive to the Borrelia burgdorferi Rev protein, a member of the 2.9 gene family locus. Infect. Immun. 66:980-986.
    • (1998) Infect. Immun. , vol.66 , pp. 980-986
    • Gilmore, R.D.1    Mbow, M.L.2
  • 20
    • 0030741784 scopus 로고    scopus 로고
    • Cloning and analysis of a Borrelia burgdorferi membrane-interactive protein exhibiting haemolytic activity
    • Guina, T., and D. B. Oliver. 1997. Cloning and analysis of a Borrelia burgdorferi membrane-interactive protein exhibiting haemolytic activity. Mol. Microbiol. 24:1201-1213.
    • (1997) Mol. Microbiol. , vol.24 , pp. 1201-1213
    • Guina, T.1    Oliver, D.B.2
  • 21
    • 0031812736 scopus 로고    scopus 로고
    • Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis
    • Hagman, K. E., P. Lahdenne, T. G. Popova, S. F. Porcella, D. R. Akins, J. D. Radolf, and M. V. Norgard. 1998. Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect. Immun. 66:2674-2683.
    • (1998) Infect. Immun. , vol.66 , pp. 2674-2683
    • Hagman, K.E.1    Lahdenne, P.2    Popova, T.G.3    Porcella, S.F.4    Akins, D.R.5    Radolf, J.D.6    Norgard, M.V.7
  • 22
    • 0031925530 scopus 로고    scopus 로고
    • Active and passive immunity against Borrelia burgdorferi decorin binding protein a (DbpA) protects against infection
    • Hanson, M. S., D. R. Cassatt, B. P. Guo, N. K. Patel, M. P. McCarthy, D. W. Dorward, and M. Hook. 1998. Active and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infection. Infect. Immun. 66:2143-2153.
    • (1998) Infect. Immun. , vol.66 , pp. 2143-2153
    • Hanson, M.S.1    Cassatt, D.R.2    Guo, B.P.3    Patel, N.K.4    McCarthy, M.P.5    Dorward, D.W.6    Hook, M.7
  • 23
    • 0025630517 scopus 로고
    • Protein H1: A role for chromatin structure in the regulation of bacterial gene expression and virulence?
    • Higgins, C. F., J. C. D. Hinton, C. S. J. Hulton, T. Owen-Hughes, G. D. Pavitt, and A. Seirafi. 1990. Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence? Mol. Microbiol. 4:2007-2012.
    • (1990) Mol. Microbiol. , vol.4 , pp. 2007-2012
    • Higgins, C.F.1    Hinton, J.C.D.2    Hulton, C.S.J.3    Owen-Hughes, T.4    Pavitt, G.D.5    Seirafi, A.6
  • 25
    • 0031663584 scopus 로고    scopus 로고
    • Temperature sensing in bacterial gene regulation - What it all boils down to
    • Hurme, R., and M. Rhen. 1998. Temperature sensing in bacterial gene regulation - what it all boils down to. Mol. Microbiol. 30:1-6.
    • (1998) Mol. Microbiol. , vol.30 , pp. 1-6
    • Hurme, R.1    Rhen, M.2
  • 26
    • 0031020230 scopus 로고    scopus 로고
    • Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection
    • Lahdenne, P., S. F. Porcella, K. E. Hagman, D. R. Akins, T. G. Popova, D. L. Cox, L. I. Katona, J. D. Radolf, and M. V. Norgard. 1997. Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection. Infect. Immun. 65:412-421.
    • (1997) Infect. Immun. , vol.65 , pp. 412-421
    • Lahdenne, P.1    Porcella, S.F.2    Hagman, K.E.3    Akins, D.R.4    Popova, T.G.5    Cox, D.L.6    Katona, L.I.7    Radolf, J.D.8    Norgard, M.V.9
  • 27
    • 0027230594 scopus 로고
    • Compilation of E. coli mRNA promoter sequences
    • Lisser, S., and H. Margalit. 1993. Compilation of E. coli mRNA promoter sequences. Nucleic Acids Res. 21:1507-1516.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1507-1516
    • Lisser, S.1    Margalit, H.2
  • 28
    • 0030048119 scopus 로고    scopus 로고
    • Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: Exploration of the paradox of the early immune response to outer surface proteins a and C in Lyme disease
    • Montgomery, R. R., S. E. Malawista, K. J. M. Feen, and L. K. Bockenstedt. 1996. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease. J. Exp. Med. 183:261-269.
    • (1996) J. Exp. Med. , vol.183 , pp. 261-269
    • Montgomery, R.R.1    Malawista, S.E.2    Feen, K.J.M.3    Bockenstedt, L.K.4
  • 29
    • 0027231449 scopus 로고
    • Standardization of medium for culturing Lyme disease spirochetes
    • Pollack, R. J., S. R. Telford, and A. Spielman. 1993. Standardization of medium for culturing Lyme disease spirochetes. J. Clin. Microbiol. 31:1251-1255.
    • (1993) J. Clin. Microbiol. , vol.31 , pp. 1251-1255
    • Pollack, R.J.1    Telford, S.R.2    Spielman, A.3
  • 30
    • 0029950581 scopus 로고    scopus 로고
    • Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family
    • Porcella, S. F., T. G. Popova, D. R. Akins, M. Li, J. D. Radolf, and M. V. Norgard. 1996. Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family. J. Bacteriol. 178:3293-3307.
    • (1996) J. Bacteriol. , vol.178 , pp. 3293-3307
    • Porcella, S.F.1    Popova, T.G.2    Akins, D.R.3    Li, M.4    Radolf, J.D.5    Norgard, M.V.6
  • 31
    • 0344197273 scopus 로고    scopus 로고
    • 22 September revision date. [Online.] [24 September 1999, last date accessed.]
    • Promoter Prediction by Neural Network. 22 September 1998, revision date. [Online.] http://www-hgc.lbl.gov/projects/promoter.html. [24 September 1999, last date accessed.]
    • (1998) Promoter Prediction by Neural Network
  • 32
    • 0032438542 scopus 로고    scopus 로고
    • Differential expression of Borrelia burgdorferi proteins during growth in vitro
    • Ramamoorthy, R., and M. T. Philipp. 1998. Differential expression of Borrelia burgdorferi proteins during growth in vitro. Infect. Immun. 66:5119-5124.
    • (1998) Infect. Immun. , vol.66 , pp. 5119-5124
    • Ramamoorthy, R.1    Philipp, M.T.2
  • 33
    • 0020053227 scopus 로고
    • Murine monoclonal antibodies specific for virulent Treponema pallidum (Nichols)
    • Robertson, S. M., J. R. Kettman, J. N. Miller, and M. V. Norgard. 1982. Murine monoclonal antibodies specific for virulent Treponema pallidum (Nichols). Infect. Immun. 36:1076-1085.
    • (1982) Infect. Immun. , vol.36 , pp. 1076-1085
    • Robertson, S.M.1    Kettman, J.R.2    Miller, J.N.3    Norgard, M.V.4
  • 34
    • 0028926240 scopus 로고
    • Induction of an outer surface protein on Borrelia burgdorferi during tick feeding
    • Schwan, T. G., J. Piesman, W. T. Golde, M. C. Dolan, and P. A. Rosa. 1995. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc. Natl. Acad. Sci. USA 92:2909-2913.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2909-2913
    • Schwan, T.G.1    Piesman, J.2    Golde, W.T.3    Dolan, M.C.4    Rosa, P.A.5
  • 35
    • 0024365376 scopus 로고
    • Ear punch biopsy method for detection and isolation of Borrelia burgdorferi from rodents
    • Sinsky, R. J., and J. Piesman. 1989. Ear punch biopsy method for detection and isolation of Borrelia burgdorferi from rodents. J. Clin. Microbiol. 27: 1723-1727.
    • (1989) J. Clin. Microbiol. , vol.27 , pp. 1723-1727
    • Sinsky, R.J.1    Piesman, J.2
  • 36
    • 0002980635 scopus 로고
    • Borrelia burgdorferi (Lyme disease, Lyme borreliosis)
    • G. L. Mandell, J. E. Bennett, and R. Dolin (ed.), Churchill Livingstone Inc., New York, N.Y.
    • Steere, A. C. 1995. Borrelia burgdorferi (Lyme disease, Lyme borreliosis), p. 2143-2155. In G. L. Mandell, J. E. Bennett, and R. Dolin (ed.), Principles and practice of infectious diseases. Churchill Livingstone Inc., New York, N.Y.
    • (1995) Principles and Practice of Infectious Diseases , pp. 2143-2155
    • Steere, A.C.1
  • 37
    • 0032560842 scopus 로고    scopus 로고
    • Immunization against Lyme disease - An important first step
    • Steigbigel, R. T., and J. L. Benach. 1998. Immunization against Lyme disease - an important first step. N. Engl. J. Med. 339:263-264.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 263-264
    • Steigbigel, R.T.1    Benach, J.L.2
  • 38
    • 0031812086 scopus 로고    scopus 로고
    • Borrelia burgdorferi Erp proteins are immunogenic in mammals infected by tick bite, and their synthesis is inducible in cultured bacteria
    • Stevenson, B., J. L. Bono, T. G. Schwan, and P. Rosa. 1998. Borrelia burgdorferi Erp proteins are immunogenic in mammals infected by tick bite, and their synthesis is inducible in cultured bacteria. Infect. Immun. 66:2648-2654.
    • (1998) Infect. Immun. , vol.66 , pp. 2648-2654
    • Stevenson, B.1    Bono, J.L.2    Schwan, T.G.3    Rosa, P.4
  • 39
    • 0030860062 scopus 로고    scopus 로고
    • Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmids
    • Stevenson, B., S. Casjens, R. van Vugt, S. F. Porcella, K. Tilly, J. L. Bono, and P. Rosa. 1997. Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmids. J. Bacteriol. 179:4285-4291.
    • (1997) J. Bacteriol. , vol.179 , pp. 4285-4291
    • Stevenson, B.1    Casjens, S.2    Van Vugt, R.3    Porcella, S.F.4    Tilly, K.5    Bono, J.L.6    Rosa, P.7
  • 40
    • 0028828202 scopus 로고
    • Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
    • Stevenson, B., T. G. Schwan, and P. A. Rosa. 1995. Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 63:4535-4539.
    • (1995) Infect. Immun. , vol.63 , pp. 4535-4539
    • Stevenson, B.1    Schwan, T.G.2    Rosa, P.A.3
  • 41
    • 0029892683 scopus 로고    scopus 로고
    • A family of genes located on four separate 32-kilobase circular plasmids in Borrelia burgdorferi B31
    • Stevenson, B., K. Tilly, and P. A. Rosa. 1996. A family of genes located on four separate 32-kilobase circular plasmids in Borrelia burgdorferi B31. J. Bacteriol. 178:3508-3516.
    • (1996) J. Bacteriol. , vol.178 , pp. 3508-3516
    • Stevenson, B.1    Tilly, K.2    Rosa, P.A.3
  • 43
    • 0029854280 scopus 로고    scopus 로고
    • Molecular cloning and characterization of nlpH, encoding a novel, surface-exposed, polymorphic, plasmid-encoded 33-kilodalton lipoprotein of Borrelia afzelii
    • Theisen, M. 1996. Molecular cloning and characterization of nlpH, encoding a novel, surface-exposed, polymorphic, plasmid-encoded 33-kilodalton lipoprotein of Borrelia afzelii. J. Bacteriol. 178:6435-6442.
    • (1996) J. Bacteriol. , vol.178 , pp. 6435-6442
    • Theisen, M.1
  • 44
    • 0029122852 scopus 로고
    • Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo
    • Wallich, R., C. Brenner, M. D. Kramer, and M. M. Simon. 1995. Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo. Infect. Immun. 63:3327-3335.
    • (1995) Infect. Immun. , vol.63 , pp. 3327-3335
    • Wallich, R.1    Brenner, C.2    Kramer, M.D.3    Simon, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.