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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 7042-7045

C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: Anticancer profile and G-quadruplex stabilization

(5) Lavrado, João a Reszka, Anthony P b Moreira, Rui a Neidle, Stephen b Paulo, Alexandra a

a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA (Portugal)

b UNIVERSITY OF LONDON (United Kingdom)

Author keywords

Anticancer; Cryptolepine; DNA binding; G Quadruplexes; Indoloquinolines

Indexed keywords

ANTINEOPLASTIC AGENT; BISANTRENE; CRYPTOLEPINE; CRYPTOLEPINE DERIVATIVE; DNA; GUANINE; NSC 748392; NSC 748393; NSC 748394; UNCLASSIFIED DRUG; VINBLASTINE;

ACUTE TOXICITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; MAXIMUM TOLERATED DOSE; VERO CELL;

ANIMALS; ANTIMALARIALS; ANTINEOPLASTIC AGENTS; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; G-QUADRUPLEXES; INDOLE ALKALOIDS; LIGANDS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TELOMERE; VERO CELLS;

MAMMALIA;

EID: 78149284692 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.09.110 Document Type: Article

Times cited : (25)

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