Synthesis of substituted indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides: Evaluation of structure-activity relationships for cytotoxicity

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 10, 2000, Pages 2461-2466

  Chen, Junjie ^a   Deady, Leslie W ^a   Desneves, José ^a   Kaye, Anthony J ^a   Finlay, Graeme J ^b   Baguley, Bruce C ^b   Denny, William A ^b  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

10H QUINDOLINE 4 CARBOXAMIDE DERIVATIVE; AMSACRINE; ANTINEOPLASTIC AGENT; BENZOTHIENO[3,2 B]QUINOLINE 4 CARBOXAMIDE DERIVATIVE; CAMPTOTHECIN; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; INDENO[1,2 B]QUINOLINE 6 CARBOXAMIDE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; COLONIC NEOPLASMS; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; INDENES; INDOLES; MICE; MOLECULAR STRUCTURE; NEOPLASM TRANSPLANTATION; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 0033811197     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00179-6     Document Type: Article

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