메뉴 건너뛰기




Volumn 16, Issue 11-12, 2010, Pages 491-497

Phosphorylation of extracellular signal-regulated kinase (ERK)-1/2 is associated with the downregulation of peroxisome proliferator-activated receptor (PPAR)-γ during polymicrobial sepsis

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADIPONECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 78149263130     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2010.00063     Document Type: Article
Times cited : (30)

References (29)
  • 1
    • 0346366979 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor-gamma ligands, 15-deoxydelta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways
    • Zingarelli B, et al. (2003) Peroxisome proliferator activator receptor-gamma ligands, 15-deoxydelta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. J. Immunol. 171:6827-37.
    • (2003) J. Immunol. , vol.171 , pp. 6827-6837
    • Zingarelli, B.1
  • 2
    • 21744458404 scopus 로고    scopus 로고
    • 15-Deoxy-delta12,14- prostaglandin J2 (15D-PGJ2), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock
    • Kaplan JM, et al. (2005) 15-Deoxy-delta12,14- prostaglandin J2 (15D-PGJ2), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock. Shock 24:59-65.
    • (2005) Shock , vol.24 , pp. 59-65
    • Kaplan, J.M.1
  • 3
    • 1542719543 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15- deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin
    • Collin M, Patel NS, Dugo L, Thiemermann C. (2004) Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15- deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin. Crit. Care Med. 32:826-31.
    • (2004) Crit. Care Med , vol.32 , pp. 826-831
    • Collin, M.1    Patel, N.S.2    Dugo, L.3    Thiemermann, C.4
  • 4
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor- gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. (1998) The peroxisome proliferator-activated receptor- gamma is a negative regulator of macrophage activation. Nature 391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 5
    • 0030957958 scopus 로고    scopus 로고
    • Decreased expression of murine PPARgamma in adipose tissue during endotoxemia
    • Hill MR, Young MD, McCurdy CM, Gimble JM. (1997) Decreased expression of murine PPARgamma in adipose tissue during endotoxemia. Endocrinology 138:3073-6.
    • (1997) Endocrinology , vol.138 , pp. 3073-3076
    • Hill, M.R.1    Young, M.D.2    McCurdy, C.M.3    Gimble, J.M.4
  • 6
    • 0033060675 scopus 로고    scopus 로고
    • Down regulation of peroxisome proliferator-activated receptor gamma expression by inflammatory cytokines and its reversal by thiazolidinediones
    • Tanaka T, et al. (1999) Down regulation of peroxisome proliferator-activated receptor gamma expression by inflammatory cytokines and its reversal by thiazolidinediones. Diabetologia 42:702-10.
    • (1999) Diabetologia , vol.42 , pp. 702-710
    • Tanaka, T.1
  • 7
    • 0033968252 scopus 로고    scopus 로고
    • Transforming growth factorbeta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma
    • Han J, et al. (2000) Transforming growth factorbeta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma. J. Biol. Chem. 275:1241-6.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1241-1246
    • Han, J.1
  • 8
    • 0030964085 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase
    • Camp HS, Tafuri SR. (1997) Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J. Biol. Chem. 272:10811-6.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10811-10816
    • Camp, H.S.1    Tafuri, S.R.2
  • 9
    • 0031057517 scopus 로고    scopus 로고
    • Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
    • Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. (1997) Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J. Biol. Chem. 272:5128-32.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5128-5132
    • Adams, M.1    Reginato, M.J.2    Shao, D.3    Lazar, M.A.4    Chatterjee, V.K.5
  • 10
    • 0034674567 scopus 로고    scopus 로고
    • Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation
    • Hauser S, et al. (2000) Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation. J. Biol. Chem. 275:18527-33.
    • (2000) J. Biol. Chem. , vol.275 , pp. 18527-18533
    • Hauser, S.1
  • 11
    • 4444252763 scopus 로고    scopus 로고
    • Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPARgamma2
    • Tanabe Y, Koga M, Saito M, Matsunaga Y, Nakayama K. (2004) Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPARgamma2. J. Cell Sci. 117:3605-14.
    • (2004) J. Cell Sci. , vol.117 , pp. 3605-3614
    • Tanabe, Y.1    Koga, M.2    Saito, M.3    Matsunaga, Y.4    Nakayama, K.5
  • 12
    • 26444600114 scopus 로고    scopus 로고
    • Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, reduces acute lung injury in endotoxemic rats
    • Liu D, et al. (2005) Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, reduces acute lung injury in endotoxemic rats. Crit. Care Med. 33:2309-16.
    • (2005) Crit. Care Med. , vol.33 , pp. 2309-2316
    • Liu, D.1
  • 13
    • 0034036640 scopus 로고    scopus 로고
    • Pathogenesis and management of multiple organ dysfunction or failure in severe sepsis and septic shock
    • RA. (2000) Pathogenesis and management of multiple organ dysfunction or failure in severe sepsis and septic shock. Crit. Care Clin. 16:337-52, vii.
    • (2000) Crit. Care Clin , vol.16
  • 14
    • 12944331141 scopus 로고    scopus 로고
    • Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats
    • Yang B, et al. (2004) Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats. BMC Pharmacol. 4:23.
    • (2004) BMC Pharmacol. , vol.4 , pp. 23
    • Yang, B.1
  • 15
    • 76549084049 scopus 로고    scopus 로고
    • Changes in peroxisome proliferator-activated receptor-gamma activity in children with septic shock
    • Kaplan JM, et al. (2010) Changes in peroxisome proliferator-activated receptor-gamma activity in children with septic shock. Intensive Care Med. 36:123-30.
    • (2010) Intensive Care Med. , vol.36 , pp. 123-130
    • Kaplan, J.M.1
  • 16
    • 38149085905 scopus 로고    scopus 로고
    • Endotoxin downregulates peroxisome proliferator- activated receptor-gamma via the increase in TNF-alpha release
    • Zhou M, Wu R, Dong W, Jacob A, Wang P. (2008) Endotoxin downregulates peroxisome proliferator- activated receptor-gamma via the increase in TNF-alpha release. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294:R84-92.
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.294
    • Zhou, M.1    Wu, R.2    Dong, W.3    Jacob, A.4    Wang, P.5
  • 17
    • 0033527419 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma1 expression in porcine white blood cells: Dynamic regulation with acute endotoxemia
    • Leininger MT, Portocarrero CP, Houseknecht KL. (1999) Peroxisome proliferator-activated receptor gamma1 expression in porcine white blood cells: dynamic regulation with acute endotoxemia. Biochem. Biophys. Res. Commun. 263:749-53.
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 749-753
    • Leininger, M.T.1    Portocarrero, C.P.2    Houseknecht, K.L.3
  • 18
    • 30144440593 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma contributes to T lymphocyte apoptosis during sepsis
    • Soller M, et al. (2006) Peroxisome proliferator-activated receptor gamma contributes to T lymphocyte apoptosis during sepsis. J. Leukoc. Biol. 79:235-43.
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 235-243
    • Soller, M.1
  • 19
    • 34247348681 scopus 로고    scopus 로고
    • Proinsulin c-peptide exerts beneficial effects in endotoxic shock in mice
    • Vish MG, et al. (2007) Proinsulin c-peptide exerts beneficial effects in endotoxic shock in mice. Crit. Care Med. 35:1348-55.
    • (2007) Crit. Care Med. , vol.35 , pp. 1348-1355
    • Vish, M.G.1
  • 20
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP kinasemediated phosphorylation of PPARgamma
    • Hu E, Kim JB, Sarraf P, Spiegelman BM. (1996) Inhibition of adipogenesis through MAP kinasemediated phosphorylation of PPARgamma. Science 274:2100-3.
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 21
    • 75649133232 scopus 로고    scopus 로고
    • Alpha-eleostearic acid suppresses proliferation of MCF-7 breast cancer cells via activation of PPARgamma and inhibition of ERK 1/2
    • Moon HS, et al. (2010) Alpha-eleostearic acid suppresses proliferation of MCF-7 breast cancer cells via activation of PPARgamma and inhibition of ERK 1/2. Cancer Sci. 101:396-402.
    • (2010) Cancer Sci. , vol.101 , pp. 396-402
    • Moon, H.S.1
  • 22
    • 33846590071 scopus 로고    scopus 로고
    • Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma
    • Burgermeister E, et al. (2007) Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol. Cell. Biol. 27:803-17.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 803-817
    • Burgermeister, E.1
  • 23
    • 0037677767 scopus 로고    scopus 로고
    • Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors
    • Iwaki M, et al. (2003) Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52:1655-63.
    • (2003) Diabetes , vol.52 , pp. 1655-1663
    • Iwaki, M.1
  • 24
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • Ouchi N, et al. (1999) Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100:2473-6.
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1
  • 25
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota T, et al. (2000) Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96:1723-32.
    • (2000) Blood , vol.96 , pp. 1723-1732
    • Yokota, T.1
  • 26
    • 33746228394 scopus 로고    scopus 로고
    • Circulating concentrations of adiponectin, an endogenous lipopolysaccharide neutralizing protein, decrease in rats with polymicrobial sepsis
    • Tsuchihashi H, et al. (2006) Circulating concentrations of adiponectin, an endogenous lipopolysaccharide neutralizing protein, decrease in rats with polymicrobial sepsis. J. Surg. Res. 134:348-53.
    • (2006) J. Surg. Res. , vol.134 , pp. 348-353
    • Tsuchihashi, H.1
  • 27
    • 0035462629 scopus 로고    scopus 로고
    • PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
    • Maeda N, et al. (2001) PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 50:2094-9.
    • (2001) Diabetes , vol.50 , pp. 2094-2099
    • Maeda, N.1
  • 28
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: A potential mechanism of insulin sensitization
    • Combs TP, et al. (2002) Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 143:998-1007.
    • (2002) Endocrinology , vol.143 , pp. 998-1007
    • Combs, T.P.1
  • 29
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu JG, et al. (2002) The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51:2968-74.
    • (2002) Diabetes , vol.51 , pp. 2968-2974
    • Yu, J.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.