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Volumn 101, Issue 2, 2010, Pages 396-402

Alpha-eleostearic acid suppresses proliferation of MCF-7 breast cancer cells via activation of PPARγ and inhibition of ERK 1/2

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ELEOSTEARIC ACID; ANTINEOPLASTIC AGENT; ESTROGEN RECEPTOR ALPHA; LINOLENIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; ROSIGLITAZONE; UNCLASSIFIED DRUG;

EID: 75649133232     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01389.x     Document Type: Article
Times cited : (47)

References (27)
  • 1
    • 41849148974 scopus 로고    scopus 로고
    • Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma
    • Tsuzuki T, Kawakami Y. Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma. Carcinogenesis 2008, 29:797-806.
    • (2008) Carcinogenesis , vol.29 , pp. 797-806
    • Tsuzuki, T.1    Kawakami, Y.2
  • 2
    • 0033955801 scopus 로고    scopus 로고
    • Newly recognized cytotoxic effect of conjugated trienoic fatty acids on cultured human tumor cells
    • Igarashi M, Miyazawa T. Newly recognized cytotoxic effect of conjugated trienoic fatty acids on cultured human tumor cells. Cancer Lett 2000, 148:173-9.
    • (2000) Cancer Lett , vol.148 , pp. 173-179
    • Igarashi, M.1    Miyazawa, T.2
  • 3
    • 0041811623 scopus 로고    scopus 로고
    • The metabolic conversion of 9,11,13-eleostearic acid (18:3) to 9,11-conjugated linoleic acid (18:2) in the rat
    • Tsuzuki T, Igarashi M, Komai M, Miyazawa T. The metabolic conversion of 9,11,13-eleostearic acid (18:3) to 9,11-conjugated linoleic acid (18:2) in the rat. J Nutr Sci Vitaminol (Tokyo) 2003, 49:195-200.
    • (2003) J Nutr Sci Vitaminol (Tokyo) , vol.49 , pp. 195-200
    • Tsuzuki, T.1    Igarashi, M.2    Komai, M.3    Miyazawa, T.4
  • 4
    • 0036792212 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action
    • Belury MA. Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action. J Nutr 2002, 132:2995-8.
    • (2002) J Nutr , vol.132 , pp. 2995-2998
    • Belury, M.A.1
  • 5
    • 38349068452 scopus 로고    scopus 로고
    • Growth inhibition of osteosarcoma cell MG-63 by a mixture of trans,trans conjugated linoleic acid isomers: possible mechanistic actions
    • Kim YS, Cerbo RM, Hah CK, Bahn KN, Kim JO, Ha YL. Growth inhibition of osteosarcoma cell MG-63 by a mixture of trans,trans conjugated linoleic acid isomers: possible mechanistic actions. J Food Sci 2008, 73:T7-15.
    • (2008) J Food Sci , vol.73
    • Kim, Y.S.1    Cerbo, R.M.2    Hah, C.K.3    Bahn, K.N.4    Kim, J.O.5    Ha, Y.L.6
  • 6
    • 0242576963 scopus 로고    scopus 로고
    • Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells
    • Kemp MQ, Jeffy BD, Romagnolo DF. Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J Nutr 2003, 133:3670-7.
    • (2003) J Nutr , vol.133 , pp. 3670-3677
    • Kemp, M.Q.1    Jeffy, B.D.2    Romagnolo, D.F.3
  • 7
    • 0036875675 scopus 로고    scopus 로고
    • Cis 9, trans 11- and trans 10, cis 12-conjugated linoleic acid isomers induce apoptosis in cultured SW480 cells
    • Miller A, Stanton C, Devery R. Cis 9, trans 11- and trans 10, cis 12-conjugated linoleic acid isomers induce apoptosis in cultured SW480 cells. Anticancer Res 2002, 22:3879-87.
    • (2002) Anticancer Res , vol.22 , pp. 3879-3887
    • Miller, A.1    Stanton, C.2    Devery, R.3
  • 8
    • 4344715276 scopus 로고    scopus 로고
    • Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation
    • Tsuzuki T, Tokuyama Y, Igarashi M, Miyazawa T. Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis 2004, 25:1417-25.
    • (2004) Carcinogenesis , vol.25 , pp. 1417-1425
    • Tsuzuki, T.1    Tokuyama, Y.2    Igarashi, M.3    Miyazawa, T.4
  • 9
    • 22444435396 scopus 로고    scopus 로고
    • Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARgamma in human colon cancer Caco-2 cells
    • Yasui Y, Hosokawa M, Sahara T. Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARgamma in human colon cancer Caco-2 cells. Prostaglandins Leukot Essent Fatty Acids 2005, 73:113-9.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.73 , pp. 113-119
    • Yasui, Y.1    Hosokawa, M.2    Sahara, T.3
  • 10
    • 2942621871 scopus 로고    scopus 로고
    • Dietary seed oil rich in conjugated linolenic acid from bitter melon inhibits azoxymethane-induced rat colon carcinogenesis through elevation of colonic PPARgamma expression and alteration of lipid composition
    • Kohno H, Yasui Y, Suzuki R, Hosokawa M, Miyashita K, Tanaka T. Dietary seed oil rich in conjugated linolenic acid from bitter melon inhibits azoxymethane-induced rat colon carcinogenesis through elevation of colonic PPARgamma expression and alteration of lipid composition. Int J Cancer 2004, 110:896-901.
    • (2004) Int J Cancer , vol.110 , pp. 896-901
    • Kohno, H.1    Yasui, Y.2    Suzuki, R.3    Hosokawa, M.4    Miyashita, K.5    Tanaka, T.6
  • 11
    • 0036283121 scopus 로고    scopus 로고
    • PPARs: transcriptional effectors of fatty acids and their derivatives
    • Hihi AK, Michalik L, Wahli W. PPARs: transcriptional effectors of fatty acids and their derivatives. Cell Mol Life Sci 2002, 59:790-8.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 790-798
    • Hihi, A.K.1    Michalik, L.2    Wahli, W.3
  • 12
    • 0034892766 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis
    • Fajas L, Debril MB, Auwerx J. Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis. J Mol Endocrinol 2001, 27:1-9.
    • (2001) J Mol Endocrinol , vol.27 , pp. 1-9
    • Fajas, L.1    Debril, M.B.2    Auwerx, J.3
  • 13
    • 0035002199 scopus 로고    scopus 로고
    • Therapeutic treatment of DMBA-induced mammary tumors with PPAR ligands
    • Pighetti GM, Novosad W, Nicholson C. Therapeutic treatment of DMBA-induced mammary tumors with PPAR ligands. Anticancer Res 2001, 21:825-9.
    • (2001) Anticancer Res , vol.21 , pp. 825-829
    • Pighetti, G.M.1    Novosad, W.2    Nicholson, C.3
  • 14
    • 58349086542 scopus 로고    scopus 로고
    • Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-dependent tumor specification
    • Yin Y, Yuan H, Zeng X, Kopelovich L, Glazer RI. Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-dependent tumor specification. Cancer Res 2009, 69:687-94.
    • (2009) Cancer Res , vol.69 , pp. 687-694
    • Yin, Y.1    Yuan, H.2    Zeng, X.3    Kopelovich, L.4    Glazer, R.I.5
  • 15
    • 49349100984 scopus 로고    scopus 로고
    • PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells
    • Schwab M, Reynders V, Loitsch S. PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells. Carcinogenesis 2008, 29:1407-14.
    • (2008) Carcinogenesis , vol.29 , pp. 1407-1414
    • Schwab, M.1    Reynders, V.2    Loitsch, S.3
  • 16
    • 0033054992 scopus 로고    scopus 로고
    • DNA damage signals induction of fas ligand in tumor cells
    • Mo YY, Beck WT. DNA damage signals induction of fas ligand in tumor cells. Mol Pharmacol 1999, 55:216-22.
    • (1999) Mol Pharmacol , vol.55 , pp. 216-222
    • Mo, Y.Y.1    Beck, W.T.2
  • 17
    • 58549093767 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells
    • Bonofiglio D, Gabriele S, Aquila S. Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells. Breast Cancer Res Treat 2009, 113:423-34.
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 423-434
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3
  • 18
    • 0043026772 scopus 로고    scopus 로고
    • Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes
    • Adhami VM, Aziz MH, Mukhtar H, Ahmad N. Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes. Clin Cancer Res 2003, 9:3176-82.
    • (2003) Clin Cancer Res , vol.9 , pp. 3176-3182
    • Adhami, V.M.1    Aziz, M.H.2    Mukhtar, H.3    Ahmad, N.4
  • 19
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990, 348:334-6.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 20
    • 0027944957 scopus 로고
    • Bcl-2 protein expression and long-term survival in breast cancer
    • Joensuu H, Pylkkanen L, Toikkanen S. Bcl-2 protein expression and long-term survival in breast cancer. Am J Pathol 1994, 145:1191-8.
    • (1994) Am J Pathol , vol.145 , pp. 1191-1198
    • Joensuu, H.1    Pylkkanen, L.2    Toikkanen, S.3
  • 21
    • 12144287188 scopus 로고    scopus 로고
    • PPAR gamma signaling exacerbates mammary gland tumor development
    • Saez E, Rosenfeld J, Livolsi A. PPAR gamma signaling exacerbates mammary gland tumor development. Genes Dev 2004, 18:528-40.
    • (2004) Genes Dev , vol.18 , pp. 528-540
    • Saez, E.1    Rosenfeld, J.2    Livolsi, A.3
  • 22
    • 33749249931 scopus 로고    scopus 로고
    • Apoptosis induced by troglitazone is both peroxisome proliferator-activated receptor-gamma- and ERK-dependent in human non-small lung cancer cells
    • Li M, Lee TW, Yim AP, Mok TS, Chen GG. Apoptosis induced by troglitazone is both peroxisome proliferator-activated receptor-gamma- and ERK-dependent in human non-small lung cancer cells. J Cell Physiol 2006, 209:428-38.
    • (2006) J Cell Physiol , vol.209 , pp. 428-438
    • Li, M.1    Lee, T.W.2    Yim, A.P.3    Mok, T.S.4    Chen, G.G.5
  • 23
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma
    • Hu E, Kim JB, Sarraf P, Spiegelman BM. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma. Science 1996, 274:2100-3.
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 24
    • 0030964085 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase
    • Camp HS, Tafuri SR. Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J Biol Chem 1997, 272:10811-6.
    • (1997) J Biol Chem , vol.272 , pp. 10811-10816
    • Camp, H.S.1    Tafuri, S.R.2
  • 25
    • 13544271958 scopus 로고    scopus 로고
    • Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer
    • Liang B, Wang S, Zhu XG, Yu YX, Cui ZR, Yu YZ. Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer. World J Gastroenterol 2005, 11:623-8.
    • (2005) World J Gastroenterol , vol.11 , pp. 623-628
    • Liang, B.1    Wang, S.2    Zhu, X.G.3    Yu, Y.X.4    Cui, Z.R.5    Yu, Y.Z.6
  • 26
    • 17844368327 scopus 로고    scopus 로고
    • The MAPK signalling pathways and colorectal cancer
    • Fang JY, Richardson BC. The MAPK signalling pathways and colorectal cancer. Lancet Oncol 2005, 6:322-7.
    • (2005) Lancet Oncol , vol.6 , pp. 322-327
    • Fang, J.Y.1    Richardson, B.C.2
  • 27
    • 0037066686 scopus 로고    scopus 로고
    • ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
    • Tang D, Wu D, Hirao A. ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J Biol Chem 2002, 277:12710-7.
    • (2002) J Biol Chem , vol.277 , pp. 12710-12717
    • Tang, D.1    Wu, D.2    Hirao, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.