Vaccine-induced antibody isotypes are skewed by impaired CD4 T cell and invariant NKT cell effector responses in MyD88-deficient mice

Journal of Immunology

Volumn 183, Issue 4, 2009, Pages 2252-2260

  Iweala, Onyinye I ^a   Smith, Donald W ^a   Matharu, Kabir S ^a   Sada Ovalle, Isabel ^b   Nguyen, Deanna D ^a   DeKruyff, Rosemarie H ^c   Umetsu, Dale T ^c   Behar, Samuel M ^b   Nagler, Cathryn R ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; GAMMA INTERFERON; MYELOID DIFFERENTIATION FACTOR 88; NEUTRALIZING ANTIBODY; SALMONELLOSIS VACCINE; BACTERIUM ANTIBODY; IMMUNOGLOBULIN CLASS; LIVE VACCINE; MYD88 PROTEIN, MOUSE; RECOMBINANT VACCINE; TOLL LIKE RECEPTOR;

ADAPTIVE IMMUNITY; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; C57BL 6 MOUSE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FEMALE; FOOT PAD; IMMUNIZATION; LYMPH NODE; MALE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; STAINING; TH1 CELL; TH2 CELL; WILD TYPE; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; MOUSE MUTANT; ORAL DRUG ADMINISTRATION; PATHOLOGY; PHYSIOLOGY; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSGENIC MOUSE;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; IMMUNOGLOBULIN ISOTYPES; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOID DIFFERENTIATION FACTOR 88; NATURAL KILLER T-CELLS; SALMONELLA VACCINES; TOLL-LIKE RECEPTORS; VACCINES, ATTENUATED; VACCINES, SYNTHETIC;

EID: 70149096704     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804011     Document Type: Article

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