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Volumn 18, Issue 6, 2010, Pages 258-265

Haemophilus influenzae and the complement system

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL POLYSACCHARIDE; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3 RECEPTOR; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4B; COMPLEMENT COMPONENT C5B; LECTIN; LIPOOLIGOSACCHARIDE; OUTER MEMBRANE PROTEIN; PHOSPHORYLCHOLINE; SIALIC ACID; VITRONECTIN; BACTERIUM ANTIBODY; COMPLEMENT; LIPID LINKED OLIGOSACCHARIDES; LIPID-LINKED OLIGOSACCHARIDES; LIPOPOLYSACCHARIDE; MEMBRANE ANTIGEN;

EID: 78049490091     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2010.03.007     Document Type: Review
Times cited : (61)

References (74)
  • 1
    • 69949109911 scopus 로고    scopus 로고
    • Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates
    • Watt, J.P. et al. (2009) Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates. Lancet 374, 903-911
    • (2009) Lancet , vol.374 , pp. 903-911
    • Watt, J.P.1
  • 2
    • 45449119665 scopus 로고    scopus 로고
    • Haemophilus influenzae type b conjugate vaccine use and effectiveness
    • Morris, S.K. et al. (2008) Haemophilus influenzae type b conjugate vaccine use and effectiveness. Lancet Infect. Dis. 8, 435-443
    • (2008) Lancet Infect. Dis. , vol.8 , pp. 435-443
    • Morris, S.K.1
  • 3
    • 0035404381 scopus 로고    scopus 로고
    • Invasive serotype a Haemophilus influenzae infections with a virulence genotype resembling Haemophilus influenzae type b: emerging pathogen in the vaccine era?
    • Adderson, E.E. et al. (2001) Invasive serotype a Haemophilus influenzae infections with a virulence genotype resembling Haemophilus influenzae type b: emerging pathogen in the vaccine era? Pediatrics 108, E18
    • (2001) Pediatrics , vol.108
    • Adderson, E.E.1
  • 4
    • 70349913920 scopus 로고    scopus 로고
    • Invasive Haemophilus influenzae disease caused by non-type b strains in Northwestern Ontario, Canada 2002-2008
    • Brown, V.M. et al. (2009) Invasive Haemophilus influenzae disease caused by non-type b strains in Northwestern Ontario, Canada, 2002-2008. Clin. Infect. Dis. 49, 1240-1243
    • (2009) Clin. Infect. Dis. , vol.49 , pp. 1240-1243
    • Brown, V.M.1
  • 5
    • 38049075261 scopus 로고    scopus 로고
    • Epidemiology of Haemophilus influenzae serotype a, North American Arctic 2000-2005
    • Bruce, M.G. et al. (2008) Epidemiology of Haemophilus influenzae serotype a, North American Arctic, 2000-2005. Emerg. Infect. Dis 14, 48-55
    • (2008) Emerg. Infect. Dis , vol.14 , pp. 48-55
    • Bruce, M.G.1
  • 6
    • 34249887147 scopus 로고    scopus 로고
    • Characterization of invasive Haemophilus influenzae disease in Manitoba, Canada 2000-2006: invasive disease due to non-type b strains
    • Tsang, R.S. et al. (2007) Characterization of invasive Haemophilus influenzae disease in Manitoba, Canada, 2000-2006: invasive disease due to non-type b strains. Clin. Infect. Dis 44, 1611-1614
    • (2007) Clin. Infect. Dis , vol.44 , pp. 1611-1614
    • Tsang, R.S.1
  • 7
    • 34547192712 scopus 로고    scopus 로고
    • Nontypeable Haemophilus influenzae: understanding virulence and commensal behavior
    • Erwin, A.L. and Smith, A.L. (2007) Nontypeable Haemophilus influenzae: understanding virulence and commensal behavior. Trends. Microbiol. 15, 355-362
    • (2007) Trends. Microbiol. , vol.15 , pp. 355-362
    • Erwin, A.L.1    Smith, A.L.2
  • 8
    • 65649084792 scopus 로고    scopus 로고
    • Nontypeable Haemophilus influenzae as a pathogen in children
    • Murphy, T.F. et al. (2009) Nontypeable Haemophilus influenzae as a pathogen in children. Pediatr. Infect. Dis. J. 28, 43-48
    • (2009) Pediatr. Infect. Dis. J. , vol.28 , pp. 43-48
    • Murphy, T.F.1
  • 9
    • 33646697956 scopus 로고    scopus 로고
    • The role of bacteria in airway inflammation in exacerbations of chronic obstructive pulmonary disease
    • Murphy, T.F. (2006) The role of bacteria in airway inflammation in exacerbations of chronic obstructive pulmonary disease. Curr. Opin. Infect. Dis. 19, 225-230
    • (2006) Curr. Opin. Infect. Dis. , vol.19 , pp. 225-230
    • Murphy, T.F.1
  • 10
    • 57349110547 scopus 로고    scopus 로고
    • Microbiology of otitis media: a moving target
    • Vergison, A. (2008) Microbiology of otitis media: a moving target. Vaccine 26 (Suppl 7), G5-10
    • (2008) Vaccine , vol.26 , Issue.SUPPL. 7
    • Vergison, A.1
  • 11
    • 1242336847 scopus 로고    scopus 로고
    • Emergence of nonencapsulated and encapsulated non-b-type invasive Haemophilus influenzae isolates in Portugal (1989-2001)
    • Bajanca, P. and Canica, M. (2004) Emergence of nonencapsulated and encapsulated non-b-type invasive Haemophilus influenzae isolates in Portugal (1989-2001). J. Clin. Microbiol. 42, 807-810
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 807-810
    • Bajanca, P.1    Canica, M.2
  • 12
    • 33847647179 scopus 로고    scopus 로고
    • The changing epidemiology of invasive Haemophilus influenzae disease, especially in persons > or = 65 years old
    • Dworkin, M.S. et al. (2007) The changing epidemiology of invasive Haemophilus influenzae disease, especially in persons > or = 65 years old. Clin. Infect. Dis. 44, 810-816
    • (2007) Clin. Infect. Dis. , vol.44 , pp. 810-816
    • Dworkin, M.S.1
  • 13
    • 68649102264 scopus 로고    scopus 로고
    • Invasive Haemophilus influenzae disease: changing epidemiology and host-parasite interactions in the 21st century
    • Ulanova, M. and Tsang, R.S. (2009) Invasive Haemophilus influenzae disease: changing epidemiology and host-parasite interactions in the 21st century. Infect. Genet. Evol. 9, 594-605
    • (2009) Infect. Genet. Evol. , vol.9 , pp. 594-605
    • Ulanova, M.1    Tsang, R.S.2
  • 14
    • 0035810399 scopus 로고    scopus 로고
    • Complement. First of two parts
    • Walport, M.J. (2001) Complement. First of two parts. N. Engl. J. Med. 344, 1058-1066
    • (2001) N. Engl. J. Med , vol.344 , pp. 1058-1066
    • Walport, M.J.1
  • 15
    • 58149334955 scopus 로고    scopus 로고
    • Ficolins: structure, function and associated diseases
    • Zhang, X.L. and Ali, M.A. (2008) Ficolins: structure, function and associated diseases. Adv. Exp. Med. Biol. 632, 105-115
    • (2008) Adv. Exp. Med. Biol. , vol.632 , pp. 105-115
    • Zhang, X.L.1    Ali, M.A.2
  • 16
    • 68049129553 scopus 로고    scopus 로고
    • Early complement proteases: C1r C1s and MASPs. A structural insight into activation and functions
    • Gal, P. et al. (2009) Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions. Mol. Immunol. 46, 2745-2752
    • (2009) Mol. Immunol. , vol.46 , pp. 2745-2752
    • Gal, P.1
  • 17
    • 70349437186 scopus 로고    scopus 로고
    • Complement regulators and inhibitory proteins
    • Zipfel, P.F. and Skerka, C. (2009) Complement regulators and inhibitory proteins. Nat. Rev. Immunol. 9, 729-740
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 729-740
    • Zipfel, P.F.1    Skerka, C.2
  • 18
    • 1842557722 scopus 로고    scopus 로고
    • Complement inhibitor C4b-binding protein -friend or foe in the innate immune system? Mol
    • Blom, A.M. et al. (2004) Complement inhibitor C4b-binding protein - friend or foe in the innate immune system? Mol. Immunol. 40, 1333- 1346
    • (2004) Immunol , vol.40 , pp. 1333-1346
    • Blom, A.M.1
  • 19
    • 47749126514 scopus 로고    scopus 로고
    • Factor H family proteins and human diseases
    • Jozsi, M. and Zipfel, P.F. (2008) Factor H family proteins and human diseases. Trends. Immunol. 29, 380-387
    • (2008) Trends. Immunol. , vol.29 , pp. 380-387
    • Jozsi, M.1    Zipfel, P.F.2
  • 20
    • 70349441306 scopus 로고    scopus 로고
    • Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
    • Heinen, S. et al. (2009) Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation. Blood 114, 2439-2447
    • (2009) Blood , vol.114 , pp. 2439-2447
    • Heinen, S.1
  • 21
    • 0345688717 scopus 로고    scopus 로고
    • Airway microvascular extravasation and luminal entry of plasma
    • Greiff, L. et al. (2003) Airway microvascular extravasation and luminal entry of plasma. Clin. Physiol. Funct. Imaging 23, 301-306
    • (2003) Clin. Physiol. Funct. Imaging , vol.23 , pp. 301-306
    • Greiff, L.1
  • 22
    • 0026027729 scopus 로고
    • Plasma exudation as a first line respiratory mucosal defence
    • Persson, C.G. et al. (1991) Plasma exudation as a first line respiratory mucosal defence. Clin. Exp. Allergy 21, 17-24
    • (1991) Clin. Exp. Allergy , vol.21 , pp. 17-24
    • Persson, C.G.1
  • 23
    • 4143059167 scopus 로고    scopus 로고
    • Complement factors c3a, c4a, and c5a in chronic obstructive pulmonary disease and asthma
    • Marc, M.M. et al. (2004) Complement factors c3a, c4a, and c5a in chronic obstructive pulmonary disease and asthma. Am. J. Respir. Cell. Mol. Biol. 31, 216-219
    • (2004) Am. J. Respir. Cell. Mol. Biol. , vol.31 , pp. 216-219
    • Marc, M.M.1
  • 24
    • 0034974922 scopus 로고    scopus 로고
    • Complement-regulator factor H and related proteins in otitis media with effusion
    • Nörkiö-Mökelö, M. et al. (2001) Complement-regulator factor H and related proteins in otitis media with effusion. Clin. Immunol. 100, 118- 126
    • (2001) Clin. Immunol. , vol.100 , pp. 118-126
    • Nörkiö-Mökelö, M.1
  • 25
    • 0033775639 scopus 로고    scopus 로고
    • Complement C3 cleavage and cytokines interleukin-1beta and tumor necrosis factor-alpha in otitis media with effusion
    • Nörkiö-Mökelö, M. et al. (2000) Complement C3 cleavage and cytokines interleukin-1beta and tumor necrosis factor-alpha in otitis media with effusion. Laryngoscope 110, 1745-1749
    • (2000) Laryngoscope , vol.110 , pp. 1745-1749
    • Nörkiö-Mökelö, M.1
  • 26
    • 70349601441 scopus 로고    scopus 로고
    • Local complement activation in nasal polyposis
    • Van Zele, T. et al. (2009) Local complement activation in nasal polyposis. Laryngoscope 119, 1753-1758
    • (2009) Laryngoscope , vol.119 , pp. 1753-1758
    • Van Zele, T.1
  • 27
    • 0028261676 scopus 로고
    • Complement activation on the nasal mucosal surface -a feature of the immediate allergic reaction in the nose
    • Andersson, M. et al. (1994) Complement activation on the nasal mucosal surface - a feature of the immediate allergic reaction in the nose. Allergy 49, 242-245
    • (1994) Allergy , vol.49 , pp. 242-245
    • Andersson, M.1
  • 28
    • 0025911234 scopus 로고
    • Complement is activated in the upper respiratory tract during influenza virus infection
    • Bjornson, A.B. et al. (1991) Complement is activated in the upper respiratory tract during influenza virus infection. Am. Rev. Respir. Dis. 143, 1062-1066
    • (1991) Am. Rev. Respir. Dis. , vol.143 , pp. 1062-1066
    • Bjornson, A.B.1
  • 29
    • 68249086824 scopus 로고    scopus 로고
    • Complement evasion strategies of pathogens -acquisition of inhibitors and beyond
    • Blom, A.M. et al. (2009) Complement evasion strategies of pathogens - acquisition of inhibitors and beyond. Mol. Immunol. 46, 2808-2817
    • (2009) Mol. Immunol. , vol.46 , pp. 2808-2817
    • Blom, A.M.1
  • 30
    • 38349048514 scopus 로고    scopus 로고
    • Complement evasion by human pathogens
    • Lambris, J.D. et al. (2008) Complement evasion by human pathogens. Nat. Rev. Microbiol. 6, 132-142
    • (2008) Nat. Rev. Microbiol. , vol.6 , pp. 132-142
    • Lambris, J.D.1
  • 31
    • 0035144425 scopus 로고    scopus 로고
    • Serum resistance in an invasive, nontypeable Haemophilus influenzae strain
    • Williams, B.J. et al. (2001) Serum resistance in an invasive, nontypeable Haemophilus influenzae strain. Infect. Immun. 69, 695- 705
    • (2001) Infect. Immun. , vol.69 , pp. 695-705
    • Williams, B.J.1
  • 32
    • 0024564482 scopus 로고
    • Resistance to serum bactericidal activity distinguishes Brazilian purpuric fever (BPF) case strains of Haemophilus influenzae biogroup aegyptius (H. aegyptius) from non-BPF strains Brazilian Purpuric Fever Study Group
    • Porto, M.H. et al. (1989) Resistance to serum bactericidal activity distinguishes Brazilian purpuric fever (BPF) case strains of Haemophilus influenzae biogroup aegyptius (H. aegyptius) from non-BPF strains. Brazilian Purpuric Fever Study Group. J. Clin.Microbiol. 27, 792-794
    • (1989) J. Clin. Microbiol. , vol.27 , pp. 792-794
    • Porto, M.H.1
  • 33
    • 34249089830 scopus 로고    scopus 로고
    • Haemophilus influenzae survival during complement-mediated attacks is promoted by Moraxella catarrhalis outer membrane vesicles
    • Tan, T.T. et al. (2007) Haemophilus influenzae survival during complement-mediated attacks is promoted by Moraxella catarrhalis outer membrane vesicles. J. Infect. Dis. 195, 1661-1670
    • (2007) J. Infect. Dis. , vol.195 , pp. 1661-1670
    • Tan, T.T.1
  • 34
    • 57649165059 scopus 로고    scopus 로고
    • Inherited complement deficiencies and bacterial infections
    • Tedesco, F. (2008) Inherited complement deficiencies and bacterial infections. Vaccine 26 (Suppl 8), I3-8
    • (2008) Vaccine , vol.26 , Issue.SUPPL. 8
    • Tedesco, F.1
  • 35
    • 0000849585 scopus 로고
    • Variation and type specificity in the bacterial species Haemophilus influenzae
    • Pittman, M. (1931) Variation and type specificity in the bacterial species Haemophilus influenzae. J. Exp. Med. 53, 471-492
    • (1931) J. Exp. Med. , vol.53 , pp. 471-492
    • Pittman, M.1
  • 36
    • 33744748623 scopus 로고    scopus 로고
    • The Haemophilus influenzae type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence
    • Sukupolvi-Petty, S. et al. (2006) The Haemophilus influenzae type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence. J. Bacteriol. 188, 3870-3877
    • (2006) J. Bacteriol. , vol.188 , pp. 3870-3877
    • Sukupolvi-Petty, S.1
  • 37
    • 0020082329 scopus 로고
    • Differential complement resistance mediates virulence of Haemophilus influenzae type b
    • Sutton, A. et al. (1982) Differential complement resistance mediates virulence of Haemophilus influenzae type b. Infect. Immun. 35, 95-104
    • (1982) Infect. Immun. , vol.35 , pp. 95-104
    • Sutton, A.1
  • 38
    • 0022508853 scopus 로고
    • Genes involved in Haemophilus influenzae type b capsule expression are part of an 18-kilobase tandem duplication
    • Hoiseth, S.K. et al. (1986) Genes involved in Haemophilus influenzae type b capsule expression are part of an 18-kilobase tandem duplication. Proc. Natl. Acad. Sci. U. S. A. 83, 1106-1110
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , pp. 1106-1110
    • Hoiseth, S.K.1
  • 39
    • 0027531318 scopus 로고
    • Genes involved in Haemophilus influenzae type b capsule expression are frequently amplified
    • Corn, P.G. et al. (1993) Genes involved in Haemophilus influenzae type b capsule expression are frequently amplified. J. Infect. Dis. 167, 356- 364
    • (1993) J. Infect. Dis. , vol.167 , pp. 356-364
    • Corn, P.G.1
  • 40
    • 0029907917 scopus 로고    scopus 로고
    • Effect of amplification of the Cap b locus on complement-mediated bacteriolysis and opsonization of type b Haemophilus influenzae
    • Noel, G.J. et al. (1996) Effect of amplification of the Cap b locus on complement-mediated bacteriolysis and opsonization of type b Haemophilus influenzae. Infect. Immun. 64, 4769-4775
    • (1996) Infect. Immun. , vol.64 , pp. 4769-4775
    • Noel, G.J.1
  • 41
    • 0026771299 scopus 로고
    • Type b capsule inhibits ingestion of Haemophilus influenzae by murine macrophages: studies with isogenic encapsulated and unencapsulated strains
    • Noel, G.J. et al. (1992) Type b capsule inhibits ingestion of Haemophilus influenzae by murine macrophages: studies with isogenic encapsulated and unencapsulated strains. J. Infect. Dis. 166, 178-182
    • (1992) J. Infect. Dis. , vol.166 , pp. 178-182
    • Noel, G.J.1
  • 42
    • 0026145512 scopus 로고
    • Complement-mediated serum activities against genetically defined capsular transformants of Haemophilus influenzae
    • Swift, A.J. et al. (1991) Complement-mediated serum activities against genetically defined capsular transformants of Haemophilus influenzae. Microb. Pathog. 10, 261-269
    • (1991) Microb. Pathog. , vol.10 , pp. 261-269
    • Swift, A.J.1
  • 43
    • 65649094075 scopus 로고    scopus 로고
    • Bacterial variation, virulence and vaccines
    • Moxon, E.R. (2009) Bacterial variation, virulence and vaccines. Microbiology 155, 997-1003
    • (2009) Microbiology , vol.155 , pp. 997-1003
    • Moxon, E.R.1
  • 44
    • 33750492960 scopus 로고    scopus 로고
    • Role of lgtC in resistance of nontypeable Haemophilus influenzae strain R2866 to human serum
    • Erwin, A.L. et al. (2006) Role of lgtC in resistance of nontypeable Haemophilus influenzae strain R2866 to human serum. Infect. Immun. 74, 6226-6235
    • (2006) Infect. Immun. , vol.74 , pp. 6226-6235
    • Erwin, A.L.1
  • 45
    • 33846199967 scopus 로고    scopus 로고
    • lgtC expression modulates resistance to C4b deposition on an invasive nontypeable Haemophilus influenzae
    • Ho, D.K. et al. (2007) lgtC expression modulates resistance to C4b deposition on an invasive nontypeable Haemophilus influenzae. J. Immunol. 178, 1002-1012
    • (2007) J. Immunol. , vol.178 , pp. 1002-1012
    • Ho, D.K.1
  • 46
    • 33646927215 scopus 로고    scopus 로고
    • Heterogeneity in tandem octanucleotides within Haemophilus influenzae lipopolysaccharide biosynthetic gene losA affects serum resistance
    • Erwin, A.L. et al. (2006) Heterogeneity in tandem octanucleotides within Haemophilus influenzae lipopolysaccharide biosynthetic gene losA affects serum resistance. Infect. Immun. 74, 3408- 3414
    • (2006) Infect. Immun. , vol.74 , pp. 3408-3414
    • Erwin, A.L.1
  • 47
    • 23944525402 scopus 로고    scopus 로고
    • Characterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae
    • Erwin, A.L. et al. (2005) Characterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae. Infect. Immun. 73, 5853-5863
    • (2005) Infect. Immun. , vol.73 , pp. 5853-5863
    • Erwin, A.L.1
  • 48
    • 16244394483 scopus 로고    scopus 로고
    • Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of Haemophilus influenzae and its role in bacterial resistance to complement-mediated killing
    • Griffin, R. et al. (2005) Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of Haemophilus influenzae and its role in bacterial resistance to complement-mediated killing. Infect. Immun. 73, 2213-2221
    • (2005) Infect. Immun. , vol.73 , pp. 2213-2221
    • Griffin, R.1
  • 49
    • 0032536372 scopus 로고    scopus 로고
    • Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killingmediated by C-reactive protein
    • Weiser, J.N. et al. (1998) Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killingmediated by C-reactive protein. J. Exp. Med. 187, 631-640
    • (1998) J. Exp. Med. , vol.187 , pp. 631-640
    • Weiser, J.N.1
  • 50
    • 39149105984 scopus 로고    scopus 로고
    • Duplicate copies of lic1 direct the addition of multiple phosphocholine residues in the lipopolysaccharide of Haemophilus influenzae
    • Fox, K.L. et al. (2008) Duplicate copies of lic1 direct the addition of multiple phosphocholine residues in the lipopolysaccharide of Haemophilus influenzae. Infect. Immun. 76, 588-600
    • (2008) Infect. Immun. , vol.76 , pp. 588-600
    • Fox, K.L.1
  • 51
    • 0034988798 scopus 로고    scopus 로고
    • The mimicry of human glycolipids and glycosphingolipids by the lipooligosaccharides of pathogenic Neisseria and Haemophilus
    • Harvey, H.A. et al. (2001) The mimicry of human glycolipids and glycosphingolipids by the lipooligosaccharides of pathogenic Neisseria and Haemophilus. J. Autoimmun. 16, 257-262
    • (2001) J. Autoimmun. , vol.16 , pp. 257-262
    • Harvey, H.A.1
  • 52
    • 33846020051 scopus 로고    scopus 로고
    • Role of complement in defense of themiddle ear revealed by restoring the virulence of nontypeable Haemophilus influenzae siaB mutants
    • Figueira,M.A. et al. (2007) Role of complement in defense of themiddle ear revealed by restoring the virulence of nontypeable Haemophilus influenzae siaB mutants. Infect. Immun. 75, 325-333
    • (2007) Infect. Immun. , vol.75 , pp. 325-333
    • Figueira, M.A.1
  • 53
    • 0035147542 scopus 로고    scopus 로고
    • Identification of a lipopolysaccharide alpha-2 3-sialyltransferase from Haemophilus influenzae
    • Hood, D.W. et al. (2001) Identification of a lipopolysaccharide alpha-2,3-sialyltransferase from Haemophilus influenzae. Mol. Microbiol. 39, 341-350
    • (2001) Mol. Microbiol. , vol.39 , pp. 341-350
    • Hood, D.W.1
  • 54
    • 23944524427 scopus 로고    scopus 로고
    • Novel sialic acid transporter of Haemophilus influenzae
    • Allen, S. et al. (2005) Novel sialic acid transporter of Haemophilus influenzae. Infect. Immun. 73, 5291-5300
    • (2005) Infect. Immun. , vol.73 , pp. 5291-5300
    • Allen, S.1
  • 55
    • 27944469933 scopus 로고    scopus 로고
    • Sialic acid transport in Haemophilus influenzae is essential for lipopolysaccharide sialylation and serum resistance and is dependent on a novel tripartite ATP-independent periplasmic transporter
    • Severi, E. et al. (2005) Sialic acid transport in Haemophilus influenzae is essential for lipopolysaccharide sialylation and serum resistance and is dependent on a novel tripartite ATP-independent periplasmic transporter. Mol. Microbiol. 58, 1173-1185
    • (2005) Mol. Microbiol. , vol.58 , pp. 1173-1185
    • Severi, E.1
  • 56
    • 77949466273 scopus 로고    scopus 로고
    • Sialic acid mediated transcriptional modulation of a highly conserved sialometabolism gene cluster in Haemophilus influenzae and its effect on virulence
    • Jenkins, G.A. et al. (2010) Sialic acid mediated transcriptional modulation of a highly conserved sialometabolism gene cluster in Haemophilus influenzae and its effect on virulence. BMC Microbiol. 10, 48
    • (2010) BMC Microbiol , vol.10 , pp. 48
    • Jenkins, G.A.1
  • 57
    • 0042307333 scopus 로고    scopus 로고
    • Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media
    • Bouchet, V. et al. (2003) Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media. Proc. Natl. Acad. Sci. U. S. A. 100, 8898-8903
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 8898-8903
    • Bouchet, V.1
  • 58
    • 0026657415 scopus 로고
    • Variation in length and sequence of porin (ompP2) alleles of non-capsulate Haemophilus influenzae
    • Forbes, K.J. et al. (1992) Variation in length and sequence of porin (ompP2) alleles of non-capsulate Haemophilus influenzae. Mol. Microbiol. 6, 2107-2112
    • (1992) Mol. Microbiol. , vol.6 , pp. 2107-2112
    • Forbes, K.J.1
  • 59
    • 58049172431 scopus 로고    scopus 로고
    • Mucosal immunization of mice with recombinant OMP P2 induces antibodies that bind to surface epitopes of multiple strains of nontypeable Haemophilus influenzae
    • Ostberg, K.L. et al. (2009) Mucosal immunization of mice with recombinant OMP P2 induces antibodies that bind to surface epitopes of multiple strains of nontypeable Haemophilus influenzae. Mucosal Immunol. 2, 63-73
    • (2009) Mucosal Immunol , vol.2 , pp. 63-73
    • Ostberg, K.L.1
  • 60
    • 33748053019 scopus 로고    scopus 로고
    • Construction of a mutant and characterization of the role of the vaccine antigen P6 in outer membrane integrity of nontypeable Haemophilus influenzae
    • Murphy, T.F. et al. (2006) Construction of a mutant and characterization of the role of the vaccine antigen P6 in outer membrane integrity of nontypeable Haemophilus influenzae. Infect. Immun. 74, 5169-5176
    • (2006) Infect. Immun. , vol.74 , pp. 5169-5176
    • Murphy, T.F.1
  • 61
    • 0037222910 scopus 로고    scopus 로고
    • Two-component systems in Haemophilus influenzae: a regulatory role for ArcA in serum resistance
    • De Souza-Hart, J.A. et al. (2003) Two-component systems in Haemophilus influenzae: a regulatory role for ArcA in serum resistance. Infect. Immun. 71, 163-172
    • (2003) Infect. Immun. , vol.71 , pp. 163-172
    • De Souza-Hart, J.A.1
  • 62
    • 0032849676 scopus 로고    scopus 로고
    • The pathogenic role of fimbriae of Haemophilus influenzae type b in murine bacteraemia and meningitis
    • Miyazaki, S. et al. (1999) The pathogenic role of fimbriae of Haemophilus influenzae type b in murine bacteraemia and meningitis. J. Med. Microbiol. 48, 383-388
    • (1999) J. Med. Microbiol. , vol.48 , pp. 383-388
    • Miyazaki, S.1
  • 63
    • 70149120375 scopus 로고    scopus 로고
    • Nontypeable Haemophilus influenzae protein E binds vitronectin and is important for serum resistance
    • Hallström, T. et al. (2009) Nontypeable Haemophilus influenzae protein E binds vitronectin and is important for serum resistance. J. Immunol. 183, 2593-2601
    • (2009) J. Immunol. , vol.183 , pp. 2593-2601
    • Hallström, T.1
  • 64
    • 33745324685 scopus 로고    scopus 로고
    • Haemophilus influenzae surface fibrils contribute to serum resistance by interacting with vitronectin
    • Hallström, T. et al. (2006) Haemophilus influenzae surface fibrils contribute to serum resistance by interacting with vitronectin. J. Immunol. 177, 430-436
    • (2006) J. Immunol. , vol.177 , pp. 430-436
    • Hallström, T.1
  • 65
    • 34248228732 scopus 로고    scopus 로고
    • Interaction with C4b-binding protein contributes to nontypeable Haemophilus influenzae serum resistance
    • Hallström, T. et al. (2007) Interaction with C4b-binding protein contributes to nontypeable Haemophilus influenzae serum resistance. J. Immunol. 178, 6359-6366
    • (2007) J. Immunol. , vol.178 , pp. 6359-6366
    • Hallström, T.1
  • 66
    • 47949122480 scopus 로고    scopus 로고
    • Haemophilus influenzae interacts with the human complement inhibitor factor H
    • Hallström, T. et al. (2008) Haemophilus influenzae interacts with the human complement inhibitor factor H. J. Immunol. 181, 537-545
    • (2008) J. Immunol. , vol.181 , pp. 537-545
    • Hallström, T.1
  • 67
    • 0037112262 scopus 로고    scopus 로고
    • Interaction of vitronectin with Haemophilus influenzae
    • Eberhard, T. and Ullberg, M. (2002) Interaction of vitronectin with Haemophilus influenzae. FEMS Immunol. Med. Microbiol. 34, 215-219
    • (2002) FEMS Immunol. Med. Microbiol. , vol.34 , pp. 215-219
    • Eberhard, T.1    Ullberg, M.2
  • 68
    • 39049089536 scopus 로고    scopus 로고
    • Identification of a novel Haemophilus influenzae protein important for adhesion to epithelial cells
    • Ronander, E. et al. (2008) Identification of a novel Haemophilus influenzae protein important for adhesion to epithelial cells. Microbes. Infect. 10, 87-96
    • (2008) Microbes. Infect. , vol.10 , pp. 87-96
    • Ronander, E.1
  • 69
    • 61849119539 scopus 로고    scopus 로고
    • Nontypeable Haemophilus influenzae adhesin protein E: characterization and biological activity
    • Ronander, E. et al. (2009) Nontypeable Haemophilus influenzae adhesin protein E: characterization and biological activity. J. Infect. Dis. 199, 522-531
    • (2009) J. Infect. Dis. , vol.199 , pp. 522-531
    • Ronander, E.1
  • 70
    • 75649102522 scopus 로고    scopus 로고
    • Protein E of Haemophilus influenzae is a ubiquitous highly conserved adhesin
    • Singh, B. et al. (2010) Protein E of Haemophilus influenzae is a ubiquitous highly conserved adhesin. J. Infect. Dis. 201, 414-419
    • (2010) J. Infect. Dis. , vol.201 , pp. 414-419
    • Singh, B.1
  • 71
    • 77749340477 scopus 로고    scopus 로고
    • Binding of complement regulators to invasive nontypeable Haemophilus influenzae is not increased compared to nasopharyngeal isolates, but serum resistance is linked to disease severity
    • Hallström, T. et al. (2010) Binding of complement regulators to invasive nontypeable Haemophilus influenzae is not increased compared to nasopharyngeal isolates, but serum resistance is linked to disease severity. J. Clin. Microbiol. 48, 921-927
    • (2010) J. Clin. Microbiol. , vol.48 , pp. 921-927
    • Hallström, T.1
  • 72
    • 57149105188 scopus 로고    scopus 로고
    • Infection in the pathogenesis and course of chronic obstructive pulmonary disease
    • Sethi, S. and Murphy, T.F. (2008) Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N. Engl. J. Med. 359, 2355-2365
    • (2008) N. Engl. J. Med. , vol.359 , pp. 2355-2365
    • Sethi, S.1    Murphy, T.F.2
  • 73
    • 6344233426 scopus 로고    scopus 로고
    • Community-wide vaccination with the heptavalent pneumococcal conjugate significantly alters the microbiology of acute otitis media
    • Block, S.L. et al. (2004) Community-wide vaccination with the heptavalent pneumococcal conjugate significantly alters the microbiology of acute otitis media. Pediatr. Infect. Dis. J. 23, 829-833
    • (2004) Pediatr. Infect. Dis. J. , vol.23 , pp. 829-833
    • Block, S.L.1
  • 74
    • 57649197924 scopus 로고    scopus 로고
    • Microbial complement inhibitors as vaccines
    • Meri, S. et al. (2008) Microbial complement inhibitors as vaccines. Vaccine 26 (Suppl 8), I113-117
    • (2008) Vaccine , vol.26 , Issue.SUPPL. 8
    • Meri, S.1


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