Nontypeable Haemophilus influenzae adhesin protein E: Characterization and biological activity

Journal of Infectious Diseases

Volumn 199, Issue 4, 2009, Pages 522-531

  Ronander, Elena ^a   Brant, Marta ^a   Eriksson, Emily ^a   Mörgelin, Matthias ^a   Hallgren, Oskar ^b   Westergren Thorsson, Gunilla ^b   Forsgren, Arne ^a   Riesbeck, Kristian ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; EPITHELIUM CELL; ESCHERICHIA COLI; EXPERIMENTAL MOUSE; HAEMOPHILUS INFECTION; HAEMOPHILUS INFLUENZAE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; VACCINATION;

ADHESINS, BACTERIAL; ANIMALS; BACTERIAL ADHESION; CELL LINE; DATA INTERPRETATION, STATISTICAL; EPITHELIAL CELLS; ESCHERICHIA COLI; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKINS; MICE; NEUTROPHILS; PEPTIDE FRAGMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 61849119539     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/596211     Document Type: Article

References (34)

1. Cripps AW, Otczyk DC. Prospects for a vaccine against otitis media. Expert Rev Vaccines 2006; 5:517-34.
2. Veeramachaneni SB, Sethi S. Pathogenesis of bacterial exacerbations of COPD. COPD 2006; 3:109-15.
3. St Geme JW III. Molecular and cellular determinants of non-typeable Haemophilus influenzae adherence and invasion. Cell Microbiol 2002; 4:191-200.
4. Bakaletz LO, Baker BD, Jurcisek JA, et al. Demonstration of type IV pilus expression and a twitching phenotype by Haemophilus influenzae. Infect Immun 2005; 73:1635-43.
5. Gilsdorf JR, McCrea KW, Marrs CF. Role of pili in Haemophilus influenzae adherence and colonization. Infect Immun 1997; 65:2997-3002.
6. Liu DF, Mason KW, Mastri M, et al. The C-terminal fragment of the internal 110-kilodalton passenger domain of the Hap protein of non-typeable Haemophilus influenzae is a potential vaccine candidate. Infect Immun 2004; 72:6961-8.
7. St Geme JW III, Falkow S, Barenkamp SJ. High-molecular-weight proteins of nontypable Haemophilus influenzae mediate attachment to human epithelial cells. Proc Natl Acad Sci USA 1993; 90:2875-9.
8. Hallstrom T, Trajkovska E, Forsgren A, Riesbeck K. Haemophilus influenzae surface fibrils contribute to serum resistance by interacting with vitronectin. J Immunol 2006; 177:430-6.
9. Hardy GG, Tudor SM, St Geme JW III. The pathogenesis of disease due to nontypeable Haemophilus influenzae. Methods Mol Med 2003; 71:1-28.
10. Hill DJ, Toleman MA, Evans DJ, Villullas S, Van Alphen L, Virji M. The variable P5 proteins of typeable and non-typeable Haemophilus influenzae target human CEACAM1. Mol Microbiol 2001; 39:850-62.
11. Reddy MS, Murphy TF, Faden HS, Bernstein JM. Middle ear mucin glycoprotein: purification and interaction with nontypable Haemophilus influenzae and Moraxella catarrhalis. Otolaryngol Head Neck Surg 1997; 116:175-80.
12. Murphy TF, Kirkham C, Lesse AJ. Construction of a mutant and characterization of the role of the vaccine antigen P6 in outer membrane integrity of nontypeable Haemophilus influenzae. Infect Immun 2006; 74:5169-76.
13. Ronander E, Brant M, Janson H, Sheldon J, Forsgren A, Riesbeck K. Identification of a novel Haemophilus influenzae protein important for adhesion to epithelial cells. Microbes Infect 2008; 10:87-96.
14. Poje G, Redfield RJ. Transformation of Haemophilus influenzae. Methods Mol Med 2003; 71:57-70.
15. Herriott RM, Meyer EM, Vogt M. Defined nongrowth media for stage II development of competence in Haemophilus influenzae. J Bacteriol 1970; 101:517-24.
16. Nordstrom T, Forsgren A, Riesbeck K. The immunoglobulin D-binding part of the outer membrane protein MID from Moraxella catarrhalis comprises 238 amino acids and a tetrameric structure. J Biol Chem 2002; 277:34692-9.
17. Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH. Well-differentiated human airway epithelial cell cultures. Methods Mol Med 2005; 107:183-206.
18. Hallstrom T, Muller SA, Morgelin M, Mollenkvist A, Forsgren A, Riesbeck K. The Moraxella IgD-binding protein MID/Hag is an oligomeric autotransporter. Microbes Infect 2008; 10:374-81.
19. Engel J, Furthmayr H. Electron microscopy and other physical methods for the characterization of extracellular matrix components: laminin, fibronectin, collagen IV, collagen VI, and proteoglycans. Methods Enzymol 1987; 145:3-78.
20. Cotter SE, Yeo HJ, Juehne T, St Geme JW III. Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin. J Bacteriol 2005; 187:4656-64.
21. Noel GJ, Love DC, Mosser DM. High-molecular-weight proteins of nontypeable Haemophilus influenzae mediate bacterial adhesion to cellular proteoglycans. Infect Immun 1994; 62:4028-33.
22. Ahren IL, Williams DL, Rice PJ, Forsgren A, Riesbeck K. The importance of a beta-glucan receptor in the nonopsonic entry of nontypeable Haemophilus influenzae into human monocytic and epithelial cells. J Infect Dis 2001; 184:150-8.
23. Papi A, Johnston SL. Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-kappaB-mediated transcription. J Biol Chem 1999; 274:9707-20.
24. Frick AG, Joseph TD, Pang L, Rabe AM, St Geme JW III, Look DC. Haemophilus influenzae stimulates ICAM-1 expression on respiratory epithelial cells. J Immunol 2000; 164:4185-96.
25. Greenwood FC, Hunter WM, Glover JS. The preparation of I-131-labelled human growth hormone of high specific radioactivity. Biochem J 1963; 89:114-23.
26. Wieland CW, Florquin S, Maris NA, et al. The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable Haemophilus influenzae from the mouse lung. J Immunol 2005; 175:6042-9.
27. Humlicek AL, Pang L, Look DC. Modulation of airway inflammation and bacterial clearance by epithelial cell ICAM-1. Am J Physiol Lung Cell Mol Physiol 2004; 287:L598-607.
28. Reddy MS, Bernstein JM, Murphy TF, Faden HS. Binding between outer membrane proteins of nontypeable Haemophilus influenzae and human nasopharyngeal mucin. Infect Immun 1996; 64:1477-9.
29. Babu MM, Priya ML, Selvan AT, et al. A database of bacterial lipoproteins (DOLOP) with functional assignments to predicted lipoproteins. J Bacteriol 2006; 188:2761-73.
30. Miyake K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin Immunol 2007; 19:3-10.
31. Chen R, Lim JH, Jono H, et al. Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways. Biochem Biophys Res Commun 2004; 324:1087-94.
32. Prymula R, Peeters P, Chrobok V, et al. Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable Haemophilus influenzae: a randomised double-blind efficacy study. Lancet 2006; 367:740-8.
33. Webb DC, Otczyk DC, Cripps AW. Investigation of the potential of a 48 kDa protein as a vaccine candidate for infection against nontypable Haemophilus influenzae. Vaccine 2007; 25:4012-9.
34. DuBois AB, Freytag LC, Clements JD. Evaluation of combinatorial vaccines against anthrax and plague in a murine model. Vaccine 2007; 25:4747-54.