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Volumn 92, Issue 3, 2010, Pages 189-197

TLQP-21, a VGF-derived peptide, prevents ethanol-induced gastric lesions: Insights into its mode of action

Author keywords

Ethanol; Gastric ulcers; Nitric oxide; Prostaglandins; Sensory fibers; TLQP 21

Indexed keywords

ALCOHOL; CAPSAICIN; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NERVE GROWTH FACTOR; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; TLQP 21; UNCLASSIFIED DRUG;

EID: 78049459635     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000319791     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 19344373566 scopus 로고    scopus 로고
    • - secretion: The role of brain-gut axis
    • DOI 10.1016/j.ejphar.2004.06.060, PII S0014299904007010
    • Konturek PC, Konturek SJ, Ochmanski W: Neuroendocrinology of gastric H+ and duodenal HCO3-secretion: The role of brain-gut axis. Eur J Pharmacol 2004; 499: 15-27. (Pubitemid 39201207)
    • (2004) European Journal of Pharmacology , vol.499 , Issue.1-2 , pp. 15-27
    • Konturek, P.C.1    Konturek, S.J.2    Ochmanski, W.3
  • 2
    • 46049093776 scopus 로고    scopus 로고
    • Gastric mucosal defense and cytoprotection: Bench to bedside
    • DOI 10.1053/j.gastro.2008.05.030, PII S0016508508007944
    • Laine L, Takeuchi K, Tarnawski A: Gastric mucosal defense and cytoprotection: Bench to bedside. Gastroenterology 2008; 135: 41-60. (Pubitemid 351899027)
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 41-60
    • Laine, L.1    Takeuchi, K.2    Tarnawski, A.3
  • 3
    • 0031043237 scopus 로고    scopus 로고
    • Central peptidergic control of gastric acid secretion
    • Geoghegan JG, Pappas TN: Central peptidergic control of gastric acid secretion. Gut 1997; 40: 164-166. (Pubitemid 27093087)
    • (1997) Gut , vol.40 , Issue.2 , pp. 164-166
    • Geoghegans, J.G.1    Pappas, T.N.2
  • 5
    • 0021796469 scopus 로고
    • Molecular cloning of a gene sequence regulated by nerve growth factor
    • Levi A, Eldridge JD, Paterson BM: Molecular cloning of a gene sequence regulated by nerve growth factor. Science 1985; 229: 393-395. (Pubitemid 15073084)
    • (1985) Science , vol.229 , Issue.4711 , pp. 393-395
    • Levi, A.1    Eldridge, J.D.2    Paterson, B.M.3
  • 6
    • 0026342227 scopus 로고
    • Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells
    • Salton SR, Fischberg DJ, Dong KW: Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells. Mol Cell Biol 1991; 11: 2335-2349.
    • (1991) Mol Cell Biol , vol.11 , pp. 2335-2349
    • Salton, S.R.1    Fischberg, D.J.2    Dong, K.W.3
  • 7
    • 0024426036 scopus 로고
    • A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway
    • Possenti R, Eldridge JD, Paterson BM, Grasso A, Levi A: A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway. EMBO J 1989; 8: 2217-2223. (Pubitemid 19273299)
    • (1989) EMBO Journal , vol.8 , Issue.8 , pp. 2217-2223
    • Possenti, R.1    Eldridge, J.D.2    Paterson, B.M.3    Grasso, A.4    Levi, A.5
  • 9
    • 78049470357 scopus 로고
    • A novel neuroendocrine gene product: Selective VGF8a gene expression and immuno-localisation of the VGF protein in endocrine and neuronal populations
    • Ferri GL, Levi A, Possenti R: A novel neuroendocrine gene product: Selective VGF8a gene expression and immuno-localisation of the VGF protein in endocrine and neuronal populations. Mol Brain Res 1992; 17: 1244-1253.
    • (1992) Mol Brain Res , vol.17 , pp. 1244-1253
    • Ferri, G.L.1    Levi, A.2    Possenti, R.3
  • 10
    • 0028020110 scopus 로고
    • Peptide V: A VGF-derived neuropeptide purified from bovine posterior pituitary
    • DOI 10.1210/en.135.6.2742
    • Liu JW, Andrews PC, Mershon JL, Yan C, Allen DL, Ben-Jonathan N: Peptide V: A VGFderived neuropeptide purified from bovine posterior pituitary. Endocrinology 1994; 135: 2742-2748. (Pubitemid 24377439)
    • (1994) Endocrinology , vol.135 , Issue.6 , pp. 2742-2748
    • Liu, J.-W.1    Andrews, P.C.2    Mershon, J.L.3    Yan, C.4    Allen, D.L.5    Ben-Jonathan, N.6
  • 12
    • 0345329860 scopus 로고    scopus 로고
    • Expression of VGF mRNA in developing neuroendocrine and endocrine tissues
    • DOI 10.1677/joe.0.1790227
    • Snyder SE, Peng B, Pintar JE, Salton SR: Expression of VGF mRNA in developing neuroendocrine and endocrine tissues. J Endocrinol 2003; 179: 227-235. (Pubitemid 37461352)
    • (2003) Journal of Endocrinology , vol.179 , Issue.2 , pp. 227-235
    • Snyder, S.E.1    Peng, B.2    Pintar, J.E.3    Salton, S.R.J.4
  • 13
    • 33645767219 scopus 로고    scopus 로고
    • Transcriptomes of purified gastric ECL and parietal cells: Identification of a novel pathway regulating acid secretion
    • Lambrecht NW, Yakubov I, Zer C, Sachs G: Transcriptomes of purified gastric ECL and parietal cells: Identification of a novel pathway regulating acid secretion. Physiol Genomics 2006; 25: 153-165.
    • (2006) Physiol Genomics , vol.25 , pp. 153-165
    • Lambrecht, N.W.1    Yakubov, I.2    Zer, C.3    Sachs, G.4
  • 15
    • 0029056717 scopus 로고
    • Induction of VGF mRNA in neurons of the rat nucleus tractus solitarius and the dorsal motor nucleus of vagus in duodenal ulceration by cysteamine
    • Kanemasa K, Okamura H, Kodama T, Ibata Y: Induction of VGF mRNA in neurons of the rat nucleus tractus solitarius and the dorsal motor nucleus of vagus in duodenal ulceration by cysteamine. Brain Res Mol Brain Res 1995; 32: 55-62.
    • (1995) Brain Res Mol Brain Res , vol.32 , pp. 55-62
    • Kanemasa, K.1    Okamura, H.2    Kodama, T.3    Ibata, Y.4
  • 16
    • 0344629700 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity
    • Alder J, Thakker-Varia S, Bangasser DA, Kuroiwa M, Plummer MR, Shors TJ, Black IB: Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J Neurosci 2003; 23: 10800-10808. (Pubitemid 37499686)
    • (2003) Journal of Neuroscience , vol.23 , Issue.34 , pp. 10800-10808
    • Alder, J.1    Thakker-Varia, S.2    Bangasser, D.A.3    Kuroiwa, M.4    Plummer, M.R.5    Shors, T.J.6    Black, I.B.7
  • 17
    • 22744455938 scopus 로고    scopus 로고
    • Pro-VGF-derived peptides induce penile erection in male rats: Involvement of paraventricular nitric oxide
    • DOI 10.1016/j.neuropharm.2005.05.015, PII S002839080500208X
    • Succu S, Mascia MS, Melis T, Sanna F, Melis MR, Possenti R, Argiolas A: Pro-VGF-derived peptides induce penile erection in male rats: Involvement of paraventricular nitric oxide. Neuropharmacology 2005; 49: 1017-1025. (Pubitemid 41503301)
    • (2005) Neuropharmacology , vol.49 , Issue.7 , pp. 1017-1025
    • Succu, S.1    Mascia, M.S.2    Melis, T.3    Sanna, F.4    Melis, M.R.5    Possenti, R.6    Argiolas, A.7
  • 19
    • 70349306996 scopus 로고    scopus 로고
    • Neuroendocrine regulatory peptide-1 and -2: Novel bioactive peptides processed from VGF
    • Toshinai K, Nakazato M: Neuroendocrine regulatory peptide-1 and -2: Novel bioactive peptides processed from VGF. Cell Mol Life Sci 2009; 66: 1939-1945.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1939-1945
    • Toshinai, K.1    Nakazato, M.2
  • 20
    • 56449107469 scopus 로고    scopus 로고
    • Pathophysiological role of TLQP-21: Gastrointestinal and metabolic functions
    • Bartolomucci A, Moles A, Levi A, Possenti R: Pathophysiological role of TLQP-21: Gastrointestinal and metabolic functions. Eat Weight Disord 2008; 13: 49-54.
    • (2008) Eat Weight Disord , vol.13 , pp. 49-54
    • Bartolomucci, A.1    Moles, A.2    Levi, A.3    Possenti, R.4
  • 23
    • 0021321719 scopus 로고
    • Antinociceptive effect of centrally administered cimetidine and dimaprit in the rat
    • Netti C, Bossa R, Galatulas I, Sibilia V, Pecile A: Antinociceptive effect of centrally administered cimetidine and dimaprit in the rat. Pharmacology 1984; 28: 262-267. (Pubitemid 14142798)
    • (1984) Pharmacology , vol.28 , Issue.5 , pp. 262-267
    • Netti, C.1    Bossa, R.2    Galatulas, I.3
  • 27
    • 0028146247 scopus 로고
    • Antiulcer effect of naringin on gastric lesions induced by ethanol in rats
    • Martín MJ, Marhuenda E, Pérez-Guerrero C, Franco JM: Antiulcer effect of naringin on gastric lesions induced by ethanol in rats. Pharmacology 1994; 49: 144-150. (Pubitemid 24236156)
    • (1994) Pharmacology , vol.49 , Issue.3 , pp. 144-150
    • Martin, M.J.1    Marhuenda, E.2    Perez-Guerrero, C.3    Franco, J.M.4
  • 28
    • 34147136778 scopus 로고    scopus 로고
    • Ticlopidine prevents the formation but delays the healing of ethanol-induced gastric lesions in the rat
    • DOI 10.1016/j.phrs.2007.01.017, PII S1043661807000412
    • Sibilia V, Pagani F, Lattuada N, De Luca V, Guidobono F, Soglian A, Netti C: Ticlopidine prevents the formation but delays the healing of ethanol-induced gastric lesions in the rat. Pharmacol Res 2007;55: 418-425. (Pubitemid 46560394)
    • (2007) Pharmacological Research , vol.55 , Issue.5 , pp. 418-425
    • Sibilia, V.1    Pagani, F.2    Lattuada, N.3    De Luca, V.4    Guidobono, F.5    Soglian, A.6    Netti, C.7
  • 29
    • 0036139717 scopus 로고    scopus 로고
    • Inhibition of gastric emptying and small intestinal transit by ethanol is mediated by capsaicin-sensitive afferent nerves
    • DOI 10.1007/s00210-001-0491-0
    • Izbéki F, Wittmann T, Jancsó G, Csáti S, Lonovics J: Inhibition of gastric emptying and small intestinal transit by ethanol is mediated by capsaicin-sensitive afferent nerves. Naunyn Schmiedebergs Arch Pharmacol 2002; 365: 17-21. (Pubitemid 34045235)
    • (2002) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.365 , Issue.1 , pp. 17-21
    • Izbeki, F.1    Wittmann, T.2    Jancso, G.3    Csati, S.4    Lonovics, J.5
  • 30
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159. (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 31
    • 0035860630 scopus 로고    scopus 로고
    • Excitatory stimulation of neurons in the arcuate nucleus inhibits gastric acid secretion via vagal pathways in anesthetized rats
    • DOI 10.1016/S0006-8993(01)02746-9, PII S0006899301027469
    • Tebbe JJ, Dietze T, Grote C, Mönnikes H: Excitatory stimulation of neurons in the arcuate nucleus inhibits gastric acid secretion via vagal pathways in anesthetized rats. Brain Res 2001; 913: 10-17. (Pubitemid 32786926)
    • (2001) Brain Research , vol.913 , Issue.1 , pp. 10-17
    • Tebbe, J.J.1    Dietze, T.2    Grote, C.3    Monnikes, H.4
  • 32
    • 0028292298 scopus 로고
    • Role of peripheral capsaicin-sensitive neurons and CGRP in central vagally mediated gastroprotective effect of TRH
    • Kato K, Yang H, Taché Y: Role of peripheral capsaicin-sensitive neurons and CGRP in central vagally mediated gastroprotective effect of TRH. Am J Physiol 1994; 266:R1610-R1614. (Pubitemid 2106557)
    • (1994) Am. J. Physiol. , vol.266 , Issue.5 PART 2
    • Kato, K.1    Yang Hong2    Tache, Y.3
  • 34
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA: Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 35
    • 0034749880 scopus 로고    scopus 로고
    • Current roles of nitric oxide in gastrointestinal disorders
    • DOI 10.1016/S0928-4257(01)00034-1, PII S0928425701000341
    • Cho CH: Current roles of nitric oxide in gastrointestinal disorders. J Physiol Paris 2001; 95: 253-256. (Pubitemid 33020246)
    • (2001) Journal of Physiology Paris , vol.95 , Issue.1-6 , pp. 253-256
    • Cho, C.H.1
  • 36
    • 0027321601 scopus 로고
    • Nitric oxide-dependent and -independent hyperaemia due to calcitonin gene-related peptide in the rat stomach
    • Holzer P, Lippe IT, Jocic M, Wachter C, Erb R, Heinemann A: Nitric oxide-dependent and -independent hyperaemia due to calcitonin gene-related peptide in the rat stomach. Br J Pharmacol 1993; 110: 404-410. (Pubitemid 23257811)
    • (1993) British Journal of Pharmacology , vol.110 , Issue.1 , pp. 404-410
    • Holzer, P.1    Lippe Th., I.2    Jocic, M.3    Wachter, Ch.4    Erb, R.5    Heinemann, A.6
  • 37
    • 11844261473 scopus 로고    scopus 로고
    • Gastric mucosal protection: From prostaglandins to gene-therapy
    • Gyires K: Gastric mucosal protection: From prostaglandins to gene-therapy. Curr Med Chem 2005; 12: 203-215. (Pubitemid 40089834)
    • (2005) Current Medicinal Chemistry , vol.12 , Issue.2 , pp. 203-215
    • Gyires, K.1
  • 39
    • 0030759367 scopus 로고    scopus 로고
    • Effects of several denervation procedures on distribution of calcitonin gene-related peptide and substance P immunoreactive in rat stomach
    • DOI 10.1023/A:1018858208532
    • Suzuki T, Kagoshima M, Shibata M, Inaba N, Onodera S, Yamaura T, Shimada H: Effects of several denervation procedures on distribution of calcitonin gene-related peptide and substance P immunoreactive in rat stomach. Dig Dis Sci 1997; 42: 1242-1254. (Pubitemid 27343452)
    • (1997) Digestive Diseases and Sciences , vol.42 , Issue.6 , pp. 1242-1254
    • Suzuki, T.1    Kagoshima, M.2    Shibata, M.3    Inaba, N.4    Onodera, S.5    Yamaura, T.6    Shimada, H.7
  • 41
    • 0025034767 scopus 로고
    • Regulation of gastric mucosal integrity by endogenous nitric oxide: Interactions with prostanoids and sensory neuropeptides in the rat
    • Whittle BJ, Lopez-Belmonte J, Moncada S: Regulation of gastric mucosal integrity by endogenous nitric oxide: Interactions with prostanoids and sensory neuropeptides in the rat. Br J Pharmacol 1990; 99: 607-611. (Pubitemid 20069172)
    • (1990) British Journal of Pharmacology , vol.99 , Issue.3 , pp. 607-611
    • Whittle, B.J.R.1    Lopez-Belmonte, J.2    Moncada, S.3
  • 42
    • 0032870521 scopus 로고    scopus 로고
    • Co-regulation of mucosal nitric oxide and prostaglandin in gastric adaptive cytoprotection
    • DOI 10.1007/s000110050489
    • Ko JK, Cho CH: Co-regulation of mucosal nitric oxide and prostaglandin in gastric adaptive cytoprotection. Inflamm Res 1999; 48: 471-478. (Pubitemid 29450245)
    • (1999) Inflammation Research , vol.48 , Issue.9 , pp. 471-478
    • Ko, J.K.S.1    Cho, C.H.2
  • 43
    • 0022321317 scopus 로고
    • 2. A possible explanation of cytoprotection
    • Takeuchi K, Nobuhara Y: Inhibition of gastric motor activity by 16,16-dimethyl prostaglandin E2. A possible explanation of cytoprotection. Dig Dis Sci 1985; 30: 1181-1188. (Pubitemid 16132379)
    • (1985) Digestive Diseases and Sciences , vol.30 , Issue.12 , pp. 1181-1188
    • Takeuchi, K.1    Nobuhara, Y.2
  • 44
    • 34548429606 scopus 로고    scopus 로고
    • Anti-inflammatory neuropeptide receptors: New therapeutic targets for immune disorders?
    • DOI 10.1016/j.tips.2007.07.001, PII S0165614707001800
    • Gonzalez-Rey E, Delgado M: Anti-inflammatory neuropeptide receptors: New therapeutic targets for immune disorders? Trends Pharmacol Sci 2007; 28: 482-491. (Pubitemid 47368698)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.9 , pp. 482-491
    • Gonzalez-Rey, E.1    Delgado, M.2


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