Ticlopidine prevents the formation but delays the healing of ethanol-induced gastric lesions in the rat

Pharmacological Research

Volumn 55, Issue 5, 2007, Pages 418-425

  Sibilia, V ^a   Pagani, F ^a   Lattuada, N ^a   De Luca, V ^a   Guidobono, F ^a   Soglian, A ^b   Netti, C ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Pharmaceutical Division   (Italy)

Author keywords

Acetylsalicylic acid; Ethanol; Gastric ulcers; Healing; Ticlopidine

Indexed keywords

NITRIC OXIDE; PROSTAGLANDIN; PROSTAGLANDIN E2; TICLOPIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG INHIBITION; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; STOMACH IRRITATION; STOMACH MUCOSA LESION; STOMACH PROTECTION; STOMACH ULCER; ULCER HEALING; ULCEROGENESIS;

ADMINISTRATION, ORAL; ANIMALS; ASPIRIN; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GASTRIC MUCOSA; INDOMETHACIN; MALE; PEPTIC ULCER HEMORRHAGE; PLATELET AGGREGATION INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; STOMACH ULCER; TICLOPIDINE; TIME FACTORS; WOUND HEALING;

EID: 34147136778     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2007.01.017     Document Type: Article

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