Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's

Biological Psychiatry

Volumn 68, Issue 10, 2010, Pages 913-921

  Mosconi, Lisa ^a   Glodzik, Lidia ^a   Mistur, Rachel ^a   McHugh, Pauline ^a   Rich, Kenneth E ^a   Javier, Elizabeth ^a   Williams, Schantel ^a   Pirraglia, Elizabeth ^a   De Santi, Susan ^a,f   Mehta, Pankaj D ^c   Zinkowski, Raymond ^d   Blennow, Kaj ^e   Pratico, Domenico ^g   De Leon, Mony J ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^d Applied NeuroSolutions Inc   (United States)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^f Bayer HealthCare Pharmaceuticals Inc   (United States)

^g TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; amyloid beta; cerebrospinal fluid (CSF) biomarkers; family history; oxidative stress; presymptomatic individuals

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BIOLOGICAL MARKER; ISOPROSTANE DERIVATIVE; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; FAMILY HISTORY; FEMALE; HUMAN; HUMAN EXPERIMENT; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; MOTHER; NERVE FIBER DEGENERATION; NEUROFIBRILLARY TANGLE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN PHOSPHORYLATION; RETROSPECTIVE STUDY; RISK FACTOR;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BIOLOGICAL MARKERS; F2-ISOPROSTANES; FAMILY HEALTH; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; MOTHERS; OXIDATIVE STRESS; TAU PROTEINS;

EID: 78049442404     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.07.011     Document Type: Article

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