메뉴 건너뛰기




Volumn 80, Issue 12, 2010, Pages 1973-1980

The Varicella-Zoster virus IE4 protein: A conserved member of the herpesviral mRNA export factors family and a potential alternative target in antiherpetic therapies

Author keywords

Antiherpetic therapies; Herpesviral homologues; IE4; MRNA export; VZV

Indexed keywords

BENZIMIDAVIR; PROTEIN IE4; PROTEIN NFX1; REV PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

EID: 78049430325     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.07.011     Document Type: Review
Times cited : (11)

References (65)
  • 1
    • 0022487151 scopus 로고
    • The complete DNA sequence of varicella-zoster virus
    • Davison A.J., Scott J.E. The complete DNA sequence of varicella-zoster virus. J Gen Virol 1986, 67(Pt 9):1759-1816.
    • (1986) J Gen Virol , vol.67 , Issue.PT 9 , pp. 1759-1816
    • Davison, A.J.1    Scott, J.E.2
  • 2
    • 0028321653 scopus 로고
    • UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression
    • Winkler M., Rice S.A., Stamminger T. UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression. J Virol 1994, 68:3943-3954.
    • (1994) J Virol , vol.68 , pp. 3943-3954
    • Winkler, M.1    Rice, S.A.2    Stamminger, T.3
  • 3
    • 70849134258 scopus 로고    scopus 로고
    • Varicella-zoster virus IE4 protein interacts with SR proteins and exports mRNAs through the TAP/NXF1 pathway
    • Ote I., Lebrun M., Vandevenne P., Bontems S., Medina-Palazon C., Manet E., et al. Varicella-zoster virus IE4 protein interacts with SR proteins and exports mRNAs through the TAP/NXF1 pathway. PLoS One 2009, 4:e7882.
    • (2009) PLoS One , vol.4
    • Ote, I.1    Lebrun, M.2    Vandevenne, P.3    Bontems, S.4    Medina-Palazon, C.5    Manet, E.6
  • 4
    • 0032030184 scopus 로고    scopus 로고
    • The herpes simplex virus immediate-early protein ICP27 shuttles between nucleus and cytoplasm
    • Mears W.E., Rice S.A. The herpes simplex virus immediate-early protein ICP27 shuttles between nucleus and cytoplasm. Virology 1998, 242:128-137.
    • (1998) Virology , vol.242 , pp. 128-137
    • Mears, W.E.1    Rice, S.A.2
  • 5
    • 0032798214 scopus 로고    scopus 로고
    • Association with the cellular export receptor CRM 1 mediates function and intracellular localization of Epstein-Barr virus SM protein, a regulator of gene expression
    • Boyle S.M., Ruvolo V., Gupta A.K., Swaminathan S. Association with the cellular export receptor CRM 1 mediates function and intracellular localization of Epstein-Barr virus SM protein, a regulator of gene expression. J Virol 1999, 73:6872-6881.
    • (1999) J Virol , vol.73 , pp. 6872-6881
    • Boyle, S.M.1    Ruvolo, V.2    Gupta, A.K.3    Swaminathan, S.4
  • 6
    • 0037126617 scopus 로고    scopus 로고
    • A novel transferable nuclear export signal mediates CRM1-independent nucleocytoplasmic shuttling of the human cytomegalovirus transactivator protein pUL69
    • Lischka P., Rosorius O., Trommer E., Stamminger T. A novel transferable nuclear export signal mediates CRM1-independent nucleocytoplasmic shuttling of the human cytomegalovirus transactivator protein pUL69. EMBO J 2001, 20:7271-7283.
    • (2001) EMBO J , vol.20 , pp. 7271-7283
    • Lischka, P.1    Rosorius, O.2    Trommer, E.3    Stamminger, T.4
  • 7
    • 0034693051 scopus 로고    scopus 로고
    • Gene activation by Varicella-zoster virus IE4 protein requires its dimerization and involves both the arginine-rich sequence, the central part, and the carboxyl-terminal cysteine-rich region
    • Baudoux L., Defechereux P., Rentier B., Piette J. Gene activation by Varicella-zoster virus IE4 protein requires its dimerization and involves both the arginine-rich sequence, the central part, and the carboxyl-terminal cysteine-rich region. J Biol Chem 2000, 275:32822-32831.
    • (2000) J Biol Chem , vol.275 , pp. 32822-32831
    • Baudoux, L.1    Defechereux, P.2    Rentier, B.3    Piette, J.4
  • 8
    • 0028854677 scopus 로고
    • Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27
    • Mears W.E., Lam V., Rice S.A. Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27. J Virol 1995, 69:935-947.
    • (1995) J Virol , vol.69 , pp. 935-947
    • Mears, W.E.1    Lam, V.2    Rice, S.A.3
  • 9
    • 0037414768 scopus 로고    scopus 로고
    • A novel nuclear export signal and a REF interaction domain both promote mRNA export by the Epstein-Barr virus EB2 protein
    • Hiriart E., Farjot G., Gruffat H., Nguyen M.V., Sergeant A., Manet E. A novel nuclear export signal and a REF interaction domain both promote mRNA export by the Epstein-Barr virus EB2 protein. J Biol Chem 2003, 278:335-342.
    • (2003) J Biol Chem , vol.278 , pp. 335-342
    • Hiriart, E.1    Farjot, G.2    Gruffat, H.3    Nguyen, M.V.4    Sergeant, A.5    Manet, E.6
  • 10
    • 0033529866 scopus 로고    scopus 로고
    • Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region
    • Kudo N., Matsumori N., Taoka H., Fujiwara D., Schreiner E.P., Wolff B., et al. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci U S A 1999, 96:9112-9117.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9112-9117
    • Kudo, N.1    Matsumori, N.2    Taoka, H.3    Fujiwara, D.4    Schreiner, E.P.5    Wolff, B.6
  • 11
    • 0035885073 scopus 로고    scopus 로고
    • Properties of two EBV Mta nuclear export signal sequences
    • Chen L., Liao G., Fujimuro M., Semmes O.J., Hayward S.D. Properties of two EBV Mta nuclear export signal sequences. Virology 2001, 288:119-128.
    • (2001) Virology , vol.288 , pp. 119-128
    • Chen, L.1    Liao, G.2    Fujimuro, M.3    Semmes, O.J.4    Hayward, S.D.5
  • 12
    • 0034130521 scopus 로고    scopus 로고
    • Epstein-Barr virus EB2 protein exports unspliced RNA via a Crm-1-independent pathway
    • Farjot G., Buisson M., Duc Dodon M., Gazzolo L., Sergeant A., Mikaelian I. Epstein-Barr virus EB2 protein exports unspliced RNA via a Crm-1-independent pathway. J Virol 2000, 74:6068-6076.
    • (2000) J Virol , vol.74 , pp. 6068-6076
    • Farjot, G.1    Buisson, M.2    Duc Dodon, M.3    Gazzolo, L.4    Sergeant, A.5    Mikaelian, I.6
  • 13
    • 0030828160 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 immediate early protein IE63 shuttles between nuclear compartments and the cytoplasm
    • Phelan A., Clements J.B. Herpes simplex virus type 1 immediate early protein IE63 shuttles between nuclear compartments and the cytoplasm. J Gen Virol 1997, 78(Pt 12):3327-3331.
    • (1997) J Gen Virol , vol.78 , Issue.PT 12 , pp. 3327-3331
    • Phelan, A.1    Clements, J.B.2
  • 14
    • 0033997928 scopus 로고    scopus 로고
    • Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathways
    • Soliman T.M., Silverstein S.J. Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathways. J Virol 2000, 74:2814-2825.
    • (2000) J Virol , vol.74 , pp. 2814-2825
    • Soliman, T.M.1    Silverstein, S.J.2
  • 15
    • 0035886713 scopus 로고    scopus 로고
    • Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway
    • Koffa M.D., Clements J.B., Izaurralde E., Wadd S., Wilson S.A., Mattaj I.W., et al. Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway. EMBO J 2001, 20:5769-5778.
    • (2001) EMBO J , vol.20 , pp. 5769-5778
    • Koffa, M.D.1    Clements, J.B.2    Izaurralde, E.3    Wadd, S.4    Wilson, S.A.5    Mattaj, I.W.6
  • 16
    • 0036892520 scopus 로고    scopus 로고
    • ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway
    • Chen I.H., Sciabica K.S., Sandri-Goldin R.M. ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway. J Virol 2002, 76:12877-12889.
    • (2002) J Virol , vol.76 , pp. 12877-12889
    • Chen, I.H.1    Sciabica, K.S.2    Sandri-Goldin, R.M.3
  • 17
    • 0029795035 scopus 로고    scopus 로고
    • The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation
    • Mears W.E., Rice S.A. The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation. J Virol 1996, 70:7445-7453.
    • (1996) J Virol , vol.70 , pp. 7445-7453
    • Mears, W.E.1    Rice, S.A.2
  • 18
    • 69249214146 scopus 로고    scopus 로고
    • Arginine methylation of the ICP27 RGG box regulates the functional interactions of ICP27 with SRPK1 and Aly/REF during herpes simplex virus 1 infection
    • Souki S.K., Sandri-Goldin R.M. Arginine methylation of the ICP27 RGG box regulates the functional interactions of ICP27 with SRPK1 and Aly/REF during herpes simplex virus 1 infection. J Virol 2009, 83:8970-8975.
    • (2009) J Virol , vol.83 , pp. 8970-8975
    • Souki, S.K.1    Sandri-Goldin, R.M.2
  • 19
    • 0141509876 scopus 로고    scopus 로고
    • A region of the Epstein-Barr virus (EBV) mRNA export factor EB2 containing an arginine-rich motif mediates direct binding to RNA
    • Hiriart E., Bardouillet L., Manet E., Gruffat H., Penin F., Montserret R., et al. A region of the Epstein-Barr virus (EBV) mRNA export factor EB2 containing an arginine-rich motif mediates direct binding to RNA. J Biol Chem 2003, 278:37790-37798.
    • (2003) J Biol Chem , vol.278 , pp. 37790-37798
    • Hiriart, E.1    Bardouillet, L.2    Manet, E.3    Gruffat, H.4    Penin, F.5    Montserret, R.6
  • 20
    • 33644870991 scopus 로고    scopus 로고
    • RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA
    • Toth Z., Lischka P., Stamminger T. RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA. Nucleic Acids Res 2006, 34:1237-1249.
    • (2006) Nucleic Acids Res , vol.34 , pp. 1237-1249
    • Toth, Z.1    Lischka, P.2    Stamminger, T.3
  • 21
    • 38449102461 scopus 로고    scopus 로고
    • The human cytomegalovirus regulatory protein UL69 and its effect on mRNA export
    • Toth Z., Stamminger T. The human cytomegalovirus regulatory protein UL69 and its effect on mRNA export. Front Biosci 2008, 13:2939-2949.
    • (2008) Front Biosci , vol.13 , pp. 2939-2949
    • Toth, Z.1    Stamminger, T.2
  • 22
    • 17044441683 scopus 로고    scopus 로고
    • The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
    • Bachi A., Braun I.C., Rodrigues J.P., Pante N., Ribbeck K., von Kobbe C., et al. The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA 2000, 6:136-158.
    • (2000) RNA , vol.6 , pp. 136-158
    • Bachi, A.1    Braun, I.C.2    Rodrigues, J.P.3    Pante, N.4    Ribbeck, K.5    von Kobbe, C.6
  • 23
    • 0033625090 scopus 로고    scopus 로고
    • REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export
    • Stutz F., Bachi A., Doerks T., Braun I.C., Seraphin B., Wilm M., et al. REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA 2000, 6:638-650.
    • (2000) RNA , vol.6 , pp. 638-650
    • Stutz, F.1    Bachi, A.2    Doerks, T.3    Braun, I.C.4    Seraphin, B.5    Wilm, M.6
  • 24
    • 0035846138 scopus 로고    scopus 로고
    • Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
    • Luo M.L., Zhou Z., Magni K., Christoforides C., Rappsilber J., Mann M., et al. Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature 2001, 413:644-647.
    • (2001) Nature , vol.413 , pp. 644-647
    • Luo, M.L.1    Zhou, Z.2    Magni, K.3    Christoforides, C.4    Rappsilber, J.5    Mann, M.6
  • 25
    • 0037175374 scopus 로고    scopus 로고
    • REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export
    • Gatfield D., Izaurralde E. REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol 2002, 159:579-588.
    • (2002) J Cell Biol , vol.159 , pp. 579-588
    • Gatfield, D.1    Izaurralde, E.2
  • 26
    • 0038381687 scopus 로고    scopus 로고
    • The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans
    • Longman D., Johnstone I.L., Caceres J.F. The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA 2003, 9:881-891.
    • (2003) RNA , vol.9 , pp. 881-891
    • Longman, D.1    Johnstone, I.L.2    Caceres, J.F.3
  • 27
    • 0035025061 scopus 로고    scopus 로고
    • Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA
    • Huang Y., Steitz J.A. Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. Mol Cell 2001, 7:899-905.
    • (2001) Mol Cell , vol.7 , pp. 899-905
    • Huang, Y.1    Steitz, J.A.2
  • 28
    • 0344211508 scopus 로고    scopus 로고
    • SR splicing factors serve as adapter proteins for TAP-dependent mRNA export
    • Huang Y., Gattoni R., Stevenin J., Steitz J.A. SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol Cell 2003, 11:837-843.
    • (2003) Mol Cell , vol.11 , pp. 837-843
    • Huang, Y.1    Gattoni, R.2    Stevenin, J.3    Steitz, J.A.4
  • 30
    • 3042836378 scopus 로고    scopus 로고
    • A molecular link between SR protein dephosphorylation and mRNA export
    • Huang Y., Yario T.A., Steitz J.A. A molecular link between SR protein dephosphorylation and mRNA export. Proc Natl Acad Sci U S A 2004, 101:9666-9670.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9666-9670
    • Huang, Y.1    Yario, T.A.2    Steitz, J.A.3
  • 31
    • 3843075319 scopus 로고    scopus 로고
    • Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins
    • Lai M.C., Tarn W.Y. Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins. J Biol Chem 2004, 279:31745-31749.
    • (2004) J Biol Chem , vol.279 , pp. 31745-31749
    • Lai, M.C.1    Tarn, W.Y.2
  • 32
    • 72849138696 scopus 로고    scopus 로고
    • Epstein-Barr virus protein EB2 contains an N-terminal transferable nuclear export signal that promotes nucleocytoplasmic export by directly binding TAP/NXF1
    • Juillard F., Hiriart E., Sergeant N., Vingtdeux-Didier V., Drobecq H., Sergeant A., et al. Epstein-Barr virus protein EB2 contains an N-terminal transferable nuclear export signal that promotes nucleocytoplasmic export by directly binding TAP/NXF1. J Virol 2009, 83:12759-12768.
    • (2009) J Virol , vol.83 , pp. 12759-12768
    • Juillard, F.1    Hiriart, E.2    Sergeant, N.3    Vingtdeux-Didier, V.4    Drobecq, H.5    Sergeant, A.6
  • 33
    • 15244351309 scopus 로고    scopus 로고
    • ICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export
    • Chen I.H., Li L., Silva L., Sandri-Goldin R.M. ICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export. J Virol 2005, 79:3949-3961.
    • (2005) J Virol , vol.79 , pp. 3949-3961
    • Chen, I.H.1    Li, L.2    Silva, L.3    Sandri-Goldin, R.M.4
  • 34
    • 67449086121 scopus 로고    scopus 로고
    • The cellular RNA export receptor TAP/NXF1 is required for ICP27-mediated export of herpes simplex virus 1 RNA, but the TREX complex adaptor protein Aly/REF appears to be dispensable
    • Johnson L.A., Li L., Sandri-Goldin R.M. The cellular RNA export receptor TAP/NXF1 is required for ICP27-mediated export of herpes simplex virus 1 RNA, but the TREX complex adaptor protein Aly/REF appears to be dispensable. J Virol 2009, 83:6335-6346.
    • (2009) J Virol , vol.83 , pp. 6335-6346
    • Johnson, L.A.1    Li, L.2    Sandri-Goldin, R.M.3
  • 35
    • 33644518219 scopus 로고    scopus 로고
    • The UL69 transactivator protein of human cytomegalovirus interacts with DEXD/H-Box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA
    • Lischka P., Toth Z., Thomas M., Mueller R., Stamminger T. The UL69 transactivator protein of human cytomegalovirus interacts with DEXD/H-Box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA. Mol Cell Biol 2006, 26:1631-1643.
    • (2006) Mol Cell Biol , vol.26 , pp. 1631-1643
    • Lischka, P.1    Toth, Z.2    Thomas, M.3    Mueller, R.4    Stamminger, T.5
  • 36
    • 0026762610 scopus 로고
    • A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing
    • Sandri-Goldin R.M., Mendoza G.E. A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing. Genes Dev 1992, 6:848-863.
    • (1992) Genes Dev , vol.6 , pp. 848-863
    • Sandri-Goldin, R.M.1    Mendoza, G.E.2
  • 37
    • 0029945537 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 protein IE63 affects the nuclear export of virus intron-containing transcripts
    • Phelan A., Dunlop J., Clements J.B. Herpes simplex virus type 1 protein IE63 affects the nuclear export of virus intron-containing transcripts. J Virol 1996, 70:5255-5265.
    • (1996) J Virol , vol.70 , pp. 5255-5265
    • Phelan, A.1    Dunlop, J.2    Clements, J.B.3
  • 38
    • 0032521214 scopus 로고    scopus 로고
    • ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif
    • Sandri-Goldin R.M. ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif. Genes Dev 1998, 12:868-879.
    • (1998) Genes Dev , vol.12 , pp. 868-879
    • Sandri-Goldin, R.M.1
  • 39
    • 0030773725 scopus 로고    scopus 로고
    • Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins
    • Soliman T.M., Sandri-Goldin R.M., Silverstein S.J. Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins. J Virol 1997, 71:9188-9197.
    • (1997) J Virol , vol.71 , pp. 9188-9197
    • Soliman, T.M.1    Sandri-Goldin, R.M.2    Silverstein, S.J.3
  • 40
    • 21044445925 scopus 로고    scopus 로고
    • The herpes simplex virus ICP27 protein: a multifunctional post-transcriptional regulator of gene expression
    • Smith R.W., Malik P., Clements J.B. The herpes simplex virus ICP27 protein: a multifunctional post-transcriptional regulator of gene expression. Biochem Soc Trans 2005, 33:499-501.
    • (2005) Biochem Soc Trans , vol.33 , pp. 499-501
    • Smith, R.W.1    Malik, P.2    Clements, J.B.3
  • 41
    • 52049115835 scopus 로고    scopus 로고
    • The many roles of the regulatory protein ICP27 during herpes simplex virus infection
    • Sandri-Goldin R.M. The many roles of the regulatory protein ICP27 during herpes simplex virus infection. Front Biosci 2008, 13:5241-5256.
    • (2008) Front Biosci , vol.13 , pp. 5241-5256
    • Sandri-Goldin, R.M.1
  • 42
    • 59749101894 scopus 로고    scopus 로고
    • Efficient nuclear export of herpes simplex virus 1 transcripts requires both RNA binding by ICP27 and ICP27 interaction with TAP/NXF1
    • Johnson L.A., Sandri-Goldin R.M. Efficient nuclear export of herpes simplex virus 1 transcripts requires both RNA binding by ICP27 and ICP27 interaction with TAP/NXF1. J Virol 2009, 83:1184-1192.
    • (2009) J Virol , vol.83 , pp. 1184-1192
    • Johnson, L.A.1    Sandri-Goldin, R.M.2
  • 43
    • 77952313512 scopus 로고    scopus 로고
    • SR proteins SRp20 and 9G8 contribute to efficient export of herpes simplex virus 1 mRNAs
    • Escudero-Paunetto L., Li L., Hernandez F.P., Sandri-Goldin R.M. SR proteins SRp20 and 9G8 contribute to efficient export of herpes simplex virus 1 mRNAs. Virology 2010, 401:155-164.
    • (2010) Virology , vol.401 , pp. 155-164
    • Escudero-Paunetto, L.1    Li, L.2    Hernandez, F.P.3    Sandri-Goldin, R.M.4
  • 44
    • 0034979001 scopus 로고    scopus 로고
    • Epstein-Barr virus SM protein interacts with mRNA in vivo and mediates a gene-specific increase in cytoplasmic mRNA
    • Ruvolo V., Gupta A.K., Swaminathan S. Epstein-Barr virus SM protein interacts with mRNA in vivo and mediates a gene-specific increase in cytoplasmic mRNA. J Virol 2001, 75:6033-6041.
    • (2001) J Virol , vol.75 , pp. 6033-6041
    • Ruvolo, V.1    Gupta, A.K.2    Swaminathan, S.3
  • 45
    • 0036776463 scopus 로고    scopus 로고
    • Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus
    • Gruffat H., Batisse J., Pich D., Neuhierl B., Manet E., Hammerschmidt W., et al. Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus. J Virol 2002, 76:9635-9644.
    • (2002) J Virol , vol.76 , pp. 9635-9644
    • Gruffat, H.1    Batisse, J.2    Pich, D.3    Neuhierl, B.4    Manet, E.5    Hammerschmidt, W.6
  • 46
    • 27644579440 scopus 로고    scopus 로고
    • Epstein-Barr virus mRNA export factor EB2 is essential for intranuclear capsid assembly and production of gp350
    • Batisse J., Manet E., Middeldorp J., Sergeant A., Gruffat H. Epstein-Barr virus mRNA export factor EB2 is essential for intranuclear capsid assembly and production of gp350. J Virol 2005, 79:14102-14111.
    • (2005) J Virol , vol.79 , pp. 14102-14111
    • Batisse, J.1    Manet, E.2    Middeldorp, J.3    Sergeant, A.4    Gruffat, H.5
  • 47
    • 0141458999 scopus 로고    scopus 로고
    • Transactivation of a viral target gene by herpes simplex virus ICP27 is posttranscriptional and does not require the endogenous promoter or polyadenylation site
    • Perkins K.D., Gregonis J., Borge S., Rice S.A. Transactivation of a viral target gene by herpes simplex virus ICP27 is posttranscriptional and does not require the endogenous promoter or polyadenylation site. J Virol 2003, 77:9872-9884.
    • (2003) J Virol , vol.77 , pp. 9872-9884
    • Perkins, K.D.1    Gregonis, J.2    Borge, S.3    Rice, S.A.4
  • 48
    • 47749092149 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 ICP27 regulates expression of a variant, secreted form of glycoprotein C by an intron retention mechanism
    • Sedlackova L., Perkins K.D., Lengyel J., Strain A.K., van Santen V.L., Rice S.A. Herpes simplex virus type 1 ICP27 regulates expression of a variant, secreted form of glycoprotein C by an intron retention mechanism. J Virol 2008, 82:7443-7455.
    • (2008) J Virol , vol.82 , pp. 7443-7455
    • Sedlackova, L.1    Perkins, K.D.2    Lengyel, J.3    Strain, A.K.4    van Santen, V.L.5    Rice, S.A.6
  • 49
    • 0037334420 scopus 로고    scopus 로고
    • The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression
    • Ruvolo V., Navarro L., Sample C.E., David M., Sung S., Swaminathan S. The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression. J Virol 2003, 77:3690-3701.
    • (2003) J Virol , vol.77 , pp. 3690-3701
    • Ruvolo, V.1    Navarro, L.2    Sample, C.E.3    David, M.4    Sung, S.5    Swaminathan, S.6
  • 50
    • 47049128026 scopus 로고    scopus 로고
    • Epstein-Barr virus SM protein functions as an alternative splicing factor
    • Verma D., Swaminathan S. Epstein-Barr virus SM protein functions as an alternative splicing factor. J Virol 2008, 82:7180-7188.
    • (2008) J Virol , vol.82 , pp. 7180-7188
    • Verma, D.1    Swaminathan, S.2
  • 51
    • 67649809761 scopus 로고    scopus 로고
    • Cyclin-dependent kinases phosphorylate the cytomegalovirus RNA export protein pUL69 and modulate its nuclear localization and activity
    • Rechter S., Scott G.M., Eickhoff J., Zielke K., Auerochs S., Muller R., et al. Cyclin-dependent kinases phosphorylate the cytomegalovirus RNA export protein pUL69 and modulate its nuclear localization and activity. J Biol Chem 2009, 284:8605-8613.
    • (2009) J Biol Chem , vol.284 , pp. 8605-8613
    • Rechter, S.1    Scott, G.M.2    Eickhoff, J.3    Zielke, K.4    Auerochs, S.5    Muller, R.6
  • 52
    • 63449097589 scopus 로고    scopus 로고
    • Cytomegaloviral protein kinase pUL97 interacts with the nuclear mRNA export factor pUL69 to modulate its intranuclear localization and activity
    • Thomas M., Rechter S., Milbradt J., Auerochs S., Muller R., Stamminger T., et al. Cytomegaloviral protein kinase pUL97 interacts with the nuclear mRNA export factor pUL69 to modulate its intranuclear localization and activity. J Gen Virol 2009, 90:567-578.
    • (2009) J Gen Virol , vol.90 , pp. 567-578
    • Thomas, M.1    Rechter, S.2    Milbradt, J.3    Auerochs, S.4    Muller, R.5    Stamminger, T.6
  • 53
    • 35448992984 scopus 로고    scopus 로고
    • Protein kinase CK2 phosphorylation of EB2 regulates its function in the production of Epstein-Barr virus infectious viral particles
    • Medina-Palazon C., Gruffat H., Mure F., Filhol O., Vingtdeux-Didier V., Drobecq H., et al. Protein kinase CK2 phosphorylation of EB2 regulates its function in the production of Epstein-Barr virus infectious viral particles. J Virol 2007, 81:11850-11860.
    • (2007) J Virol , vol.81 , pp. 11850-11860
    • Medina-Palazon, C.1    Gruffat, H.2    Mure, F.3    Filhol, O.4    Vingtdeux-Didier, V.5    Drobecq, H.6
  • 54
    • 0033015083 scopus 로고    scopus 로고
    • Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27
    • Zhi Y., Sandri-Goldin R.M. Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27. J Virol 1999, 73:3246-3257.
    • (1999) J Virol , vol.73 , pp. 3246-3257
    • Zhi, Y.1    Sandri-Goldin, R.M.2
  • 55
    • 77649196687 scopus 로고    scopus 로고
    • ICP27 phosphorylation site mutants display altered functional interactions with cellular export factors Aly/REF and TAP/NXF1 but are able to bind herpes simplex virus 1 RNA
    • Corbin-Lickfett K.A., Rojas S., Li L., Cocco M.J., Sandri-Goldin R.M. ICP27 phosphorylation site mutants display altered functional interactions with cellular export factors Aly/REF and TAP/NXF1 but are able to bind herpes simplex virus 1 RNA. J Virol 2010, 84:2212-2222.
    • (2010) J Virol , vol.84 , pp. 2212-2222
    • Corbin-Lickfett, K.A.1    Rojas, S.2    Li, L.3    Cocco, M.J.4    Sandri-Goldin, R.M.5
  • 56
    • 77649203653 scopus 로고    scopus 로고
    • ICP27 phosphorylation site mutants are defective in herpes simplex virus 1 replication and gene expression
    • Rojas S., Corbin-Lickfett K.A., Escudero-Paunetto L., Sandri-Goldin R.M. ICP27 phosphorylation site mutants are defective in herpes simplex virus 1 replication and gene expression. J Virol 2010, 84:2200-2211.
    • (2010) J Virol , vol.84 , pp. 2200-2211
    • Rojas, S.1    Corbin-Lickfett, K.A.2    Escudero-Paunetto, L.3    Sandri-Goldin, R.M.4
  • 57
    • 0027962510 scopus 로고
    • Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors
    • Gui J.F., Tronchere H., Chandler S.D., Fu X.D. Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors. Proc Natl Acad Sci U S A 1994, 91:10824-10828.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10824-10828
    • Gui, J.F.1    Tronchere, H.2    Chandler, S.D.3    Fu, X.D.4
  • 58
    • 58249093940 scopus 로고    scopus 로고
    • The SR protein family of splicing factors: master regulators of gene expression
    • Long J.C., Caceres J.F. The SR protein family of splicing factors: master regulators of gene expression. Biochem J 2009, 417:15-27.
    • (2009) Biochem J , vol.417 , pp. 15-27
    • Long, J.C.1    Caceres, J.F.2
  • 59
    • 0037387122 scopus 로고    scopus 로고
    • ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation
    • Sciabica K.S., Dai Q.J., Sandri-Goldin R.M. ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation. EMBO J 2003, 22:1608-1619.
    • (2003) EMBO J , vol.22 , pp. 1608-1619
    • Sciabica, K.S.1    Dai, Q.J.2    Sandri-Goldin, R.M.3
  • 60
    • 0242363216 scopus 로고    scopus 로고
    • Requirement of varicella-zoster virus immediate-early 4 protein for viral replication
    • Sato B., Sommer M., Ito H., Arvin A.M. Requirement of varicella-zoster virus immediate-early 4 protein for viral replication. J Virol 2003, 77:12369-12372.
    • (2003) J Virol , vol.77 , pp. 12369-12372
    • Sato, B.1    Sommer, M.2    Ito, H.3    Arvin, A.M.4
  • 63
    • 49849102544 scopus 로고    scopus 로고
    • Knockdown of cellular RNA helicase DDX3 by short hairpin RNAs suppresses HIV-1 viral replication without inducing apoptosis
    • Ishaq M., Hu J., Wu X., Fu Q., Yang Y., Liu Q., et al. Knockdown of cellular RNA helicase DDX3 by short hairpin RNAs suppresses HIV-1 viral replication without inducing apoptosis. Mol Biotechnol 2008, 39:231-238.
    • (2008) Mol Biotechnol , vol.39 , pp. 231-238
    • Ishaq, M.1    Hu, J.2    Wu, X.3    Fu, Q.4    Yang, Y.5    Liu, Q.6
  • 64
    • 0035991720 scopus 로고    scopus 로고
    • Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole l-riboside with a unique mode of action
    • Biron K.K., Harvey R.J., Chamberlain S.C., Good S.S., Smith A.A., Davis M.G., et al. Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole l-riboside with a unique mode of action. Antimicrob Agents Chemother 2002, 46:2365-2372.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2365-2372
    • Biron, K.K.1    Harvey, R.J.2    Chamberlain, S.C.3    Good, S.S.4    Smith, A.A.5    Davis, M.G.6
  • 65
    • 33845994066 scopus 로고    scopus 로고
    • Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication
    • Bahner I., Sumiyoshi T., Kagoda M., Swartout R., Peterson D., Pepper K., et al. Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication. Mol Ther 2007, 15:76-85.
    • (2007) Mol Ther , vol.15 , pp. 76-85
    • Bahner, I.1    Sumiyoshi, T.2    Kagoda, M.3    Swartout, R.4    Peterson, D.5    Pepper, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.