The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Glynn, Sharon A ^a,b   O'Sullivan, Dermot ^a   Eustace, Alex J ^a   Clynes, Martin ^a   O'Donovan, Norma ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPACTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PACLITAXEL; SIMVASTATIN; DRUG DERIVATIVE;

ANALYSIS OF VARIANCE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER ADJUVANT THERAPY; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SENSITIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LUNG CARCINOMA; MELANOMA; MIGRATION INHIBITION; MITOSIS INHIBITION; STUDENT T TEST; BREAST TUMOR; CELL ADHESION; CELL MOTION; CELL PROLIFERATION; DRUG EFFECT; FEMALE; LUNG TUMOR; MALE; PATHOLOGY; SKIN TUMOR; TUMOR CELL LINE;

APOPTOSIS; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; LUNG NEOPLASMS; MALE; MELANOMA; NEOPLASM INVASIVENESS; SIMVASTATIN; SKIN NEOPLASMS;

EID: 39749120859     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-9     Document Type: Article

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