Antileukemic action of (-)-epicatechin in the spleen of rats with acute myeloid leukemia

Food and Chemical Toxicology

Volumn 48, Issue 12, 2010, Pages 3391-3397

  Papiez, M A ^a   Baran, J ^b   Bukowska Strakova K ^b   Wiczkowski, W ^c  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

Author keywords

( ) Epicatechin; Acute myeloid leukemia; Apoptosis; Comet assay; DNA damage; Spleen

Indexed keywords

EPICATECHIN; LIPOCORTIN 5;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL COUNT; CELL POPULATION; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG BLOOD LEVEL; DRUG MECHANISM; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; IN VIVO STUDY; MALE; NONHUMAN; RAT; SPLEEN CELL; SPLEEN WEIGHT;

ANIMALS; ANNEXIN A5; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BODY WEIGHT; CATECHIN; CELL LINE; COMET ASSAY; DNA DAMAGE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; LEUKEMIA, MYELOID, ACUTE; METHYLATION; ORGAN SIZE; OXIDATION-REDUCTION; PHOSPHATIDYLSERINES; PURINES; RATS; SPLEEN;

ANIMALIA; RATTUS;

EID: 78049417720     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.09.010     Document Type: Article

References (44)

1. Ahmad N., Feyes D.K., Nieminen A.L., Agarwal R., Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J. Natl. Cancer Inst. 1997, 89:1881-1886.
2. Ahmad N., Gupta S., Mukhtar H. Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor κB in cancer cells versus normal cells. Arch. Biochem. Biophys. 2000, 376:338-346.
3. Avendano C., Menendez J.C. Medicinal chemistry of anticancer drugs 2008, Elsevier, Hungary. first ed.
4. Azam S., Hadi N., Khan N.U., Hadi S.M. Prooxidant property of green tea polyphenols epicatechin and epigallocatechin-3-gallate: implications for anticancer properties. Toxicol. In Vitro 2004, 18:555-561.
5. Bruno J.G., Heman T.S., Cano V.L., Stribling L., Kiel J.L. Selective cytotoxicity of 3-amino-l-tyrosine correlates with peroxidase activity. In Vitro Cell. Biol. Anim. 1999, 35:376-382.
6. Chai P.C., Long L.H., Halliwell B. Contribution of hydrogen peroxide to the cytotoxicity of green tea and red wines. Biochem. Biophys. Res. Commun. 2003, 304:650-654.
7. Delgado M.E., Haza A.I., Garcia A., Morales P. Dietary polyphenols protect against N-nitrosamines and benzo(a)pyrene-induced DNA damage (strand breaks and oxidized purines/pyrimidines) in HepG2 human hepatoma cells. Eur. J. Nutr. 2008, 47:479-490.
8. Feng R., Ni H.M., Wang S.Y., Tourkova I.L., Shurin M.R., Harada H. Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress. J. Biol. Chem. 2007, 282:13468-13476.
9. Goldman R., Claycamp G.H., Sweetland M.A., Sedlov A.V., Tyurin V.A., Kisin E.R., Tyurina Y.Y., Ritov V.B., Wenger S.L., Grant S.G., Kagan V.E. Myeloperoxidase-catalyzed redox-cycling pf phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells. Free Radic. Biol. Med. 1999, 27:1050-1063.
10. Hubeek I., Comijn E.M., Van Der Wilt C.L., Merriman R.L., Padron J.M., Kaspers G.J.L., Peters G.J. CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo. Oncol. Rep. 2008, 19:1517-1523.
11. Jemal A., Tiwari R., Murray T., Ghafoor A., Samuels A., Ward E., Feuer E.J., Thun M.J. Cancer statistics. CA Cancer J. Clin. 2004, 54:8-29.
12. Kang X., Jin S., Zhang Q. Antitumor and antiangiogenic activity of soy phytoestrogen on 7,12-dimethylbenz(alpha)anthracene-induced mammary tumors following ovariectomy in Sprague-Dawley rats. J. Food Sci. 2009, 74:H237-H242.
13. Karanjawala Z.E., Murphy N., Hinton D.R., Hsieh C.L., Lieber M.R. Oxygen metabolism cause chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr. Biol. 2002, 12:397-402.
14. Kuhnel G., Spencer J.P.E., Schroeter H., Shenoy B., Debnam E.S., Srai K.S., Rice-Evans C., Hahm U. Epicatechin and catechin are O-metylated and glucuronidated in the small intestine. Biochem. Biophys. Res. Commun. 2000, 277:507-512.
15. Kuo Y.C.H., Yu Ch.L., Liu Ch.Y., Wang S.F., Pan P.Ch., Wu M.T., Ho Ch.K., Lo Y.S., Li Y., Christiani D.C. A population-based, case-control study of green tea consumption and leukemia risk in southwestern Taiwan. Cancer Cause Control 2009, 20:57-65. the Kaohsiung Leukemia Research Group.
16. Loeb L.A. A mutator phenotype in cancer. Cancer Res. 2001, 61:3230-3239.
17. Loeb L.A., Bielas J.H., Beckman R.A. Cancers exhibit a mutator phenotype: clinical implications. Cancer Res. 2008, 68:3551-3557.
18. Martens A.C.M., Johnson R.J., Kaizer H., Hagenbeek A. Characteristics of a monoclonal antibody (RM124) against acute myelocytic leukemia cells. Exp. Hematol. 1984, 12:667-671.
19. Martens A.C.M., Van Bekkum D.W., Hagenbeek A. The BN acute myelocytic leukemia (BNML) (a rat model for studying human acute myelocytic leukemia (AML)). Leukemia 1990, 4:241-257.
20. Martin S., Gary G., Jacob M. Drug therapy for acute myeloid leukemia. Blood 2005, 106:1154-1163.
21. Mills K.D., Ferguson D.O., Alt F.W. The role of DANN breaks in genomic instability and tumorogenesis. Immunol. Rev. 2003, 194:77-95.
22. Moiseeva E.P., Almeida G.M., Jones G.D., Manson M.M. Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. Mol. Cancer Ther. 2007, 6:3071-3079.
23. Nair C.K., Salvi V.P. Protection of DNA from gamma-radiation induced strand breaks by epicatechin. Mutat. Res. 2008, 650:48-54.
24. Nakazato T., Ito K., Miyakawa Y., Kinjo K., Yamada T., Hozumi N., Ikeda Y., Kizaki M. Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemia cells via modulation of reactive oxygen species production in vitro and inhibits tumor growth in vivo. Hematol. J. 2005, 90:317-325.
25. Nakazato T., Sagawa M., Yamato K., Xian M., Yamamoto T., Suematsu M., Ikeda Y., Kizaki M. Myeloperoxidase is a key regulator of oxidative stress-mediated apoptosis in myeloid leukemia cells. Clin. Cancer Res. 2007, 13:5436-5445.
26. Noda C., He J., Takano T., Tanaka C., Kondo T., Tohyama K., Yamamura H., Tohyama Y. Induction of apoptosis by epigallocatechin-3-gallate in human lymphoblastoid B cells. Biochem. Biophys. Res. Commun. 2007, 362:951-957.
27. Noe V., Penuelas S., Lamuela-Raventos R.M., Permanyer J., Ciudad C.J., Izquierdo-Pulido M. Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells. J. Nutr. 2004, 134:2509-2516.
28. Oikawa S., Furukawa A., Asada H., Hirakawa K., Kawanishi S. Catechins induce oxidative damage to cellular and isolated DNA through the generation of reactive oxygen species. Free Radic. Res. 2003, 37:881-890.
29. Papież M.A., Dybała M., Sowa-Kućma M., Krzyściak W., Taha H., Józkowicz A., Nowak G. Evaluation of oxidative status and depression-like responses in Brown Norway rats with acute myeloid leukemia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2009, 33:596-604.
30. Piskula M.K., Terao J. Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues. J. Nutr. 1998, 128:1172-1178.
31. Roos W.P., Kaina B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 2006, 12:440-450.
32. Sakagami H., Arakawa H., Maeda M., Satoh K., Kadofuku T., Fukuchi K., Gomi K. Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants. Anticancer Res. 2001, 21:2633-2641.
33. Sallmyr A., Fan J., Rassool F.V. Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair. Cancer Lett. 2008, 270:1-9.
34. Schroeter H., Heiss C., Balzer J., Kleinbongard P., Keen C.L., Hollenberg N.K., Sies H., Kwik-Uribe C., Schmitz H.H., Kelm M. (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc. Natl. Acad. Sci. USA 2006, 103:1024-1029.
35. Shammas M.A., Neri P., Koley H., Batchu R.B., Bertheau R.C., Munshi V., Prabhala R., Fulciniti M.F., Tai Y.T., Treon S.P., Goyal R.K., Anderson K.C., Munshi N.C. Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications. Blood 2006, 108:2804-2810.
36. Spalteholz H., Furtmuller P.G., Jakopitsch Ch., Obinger Ch., Schewe T., Sies H., Arnhold J. Kinetic evidence for rapid oxidation of (-)-epicatechin by human myelopeoxidase. Biochem. Biophys. Res. Commun. 2008, 371:810-813.
37. Spencer J.P.E., Schroeter H., Kuhnle G., Srai S.K.S., Tyrrell R.M., Hahn U., Rice-Evans C. Epicatechin and 1st in vivo metabolite, 3′-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation. Biochem. J. 2001, 354:493-500.
38. Su Ch.Ch., Yang J.S., Lin S.Y., Lu H.F., Lin S.S., Chang Y.H., Huang W.W., Li Y.Ch., Chang S.J., Chung J.G. Curcumin inhibits WEHI-3 leukemia cells in BALB/c mice in vivo. In Vivo 2008, 22:63-68.
39. Talas Z.S., Bayraktar N., Ozdemir I., Gok Y., Yilmaz I. The effects of synthetic organoselenium compounds on nitric oxide in DMBA-induced rat liver. J. Environ. Biol. 2009, 30:591-593.
40. Tice R.R., Andrews P.W., Hirai O., Singh N.P. The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. Adv. Exp. Med. Biol. 1991, 283:157-164.
41. Van Bekkum D.W., Hagenbeek A. Relevance of the BN leukemia as a model for human acute myeloid leukemia. Blood Cell 1977, 3:565-579.
42. Yamamoto T., Hsu S., Lewis J., Wataha J., Dickinson D., Singh B., Bollag W.B., Lockwood P., Ueta E., Osaki T., Schuster G. Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells. J. Pharmacol. Exp. Ther. 2003, 307:230-236.
43. Yu Ch.S., Lai K.Ch., Yang J.S., Chiang J.H., Lu Ch.Ch., Wu Ch.L., Lin J.P., Liao Ch.L., Tang N.Y., Wood W.G., Chung J.G. Quercetin inhibited murine leukemia WEHI-3 cells in vivo and promoted immune response. Phytother. Res. 2010, 24:163-168.
44. Zhou F., Zhang W., Wie Y., Zhou D., Su Z., Meng X., Hui L., Tian W. The changes of oxidative stress and human 8-hydroxyguanine glycosylase 1 gene expression in depressive patients with acute leukemia. Leuk. Res. 2007, 31:387-393.