Protection of DNA from gamma-radiation induced strand breaks by Epicatechin

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 650, Issue 1, 2008, Pages 48-54

  Nair, Cherupally Krishnan Krishnan ^a   Salvi, Veena Prakash ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Comet assay; DNA strand breaks; Epicatechin; Radiation exposure; Radiation protection; Radioprotector

Indexed keywords

EPICATECHIN; PLASMID DNA; PLASMID PBR322 DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; GAMMA RADIATION; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION PROTECTION;

ANIMALS; CATECHIN; DNA; GAMMA RAYS; LEUKOCYTES; MALE; MICE; RADIATION-PROTECTIVE AGENTS;

MUS;

EID: 38049144483     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2007.10.001     Document Type: Article

References (35)

1. Natsume M., Osakabe N., Oyama M., Sasaki M., Baba S., Nakamura Y., Osawa T., and Terao J. Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat. Free Radical Bio. Med. 34 (2003) 840-849
2. Edwards-Jones V., Buck R., Shawcross S.G., Dawson M.M., and Dunn K. The effect of essential oils on methicillin-resistant Staphylococcus aureus using a dressing model. Burns 30 8 (2004) 772-777
3. Yamaguchi K., Honda M., Ikigai H., Hara Y., and Shimamura T. Inhibitory effects of (-)-epigallocatechin gallate on the life cycle of human immunodeficiency virus type 1 (HIV-1). Antiviral Res. 53 1 (2002) 19-34
4. McCormick T.G., Nance C.L., Williamson M.P., and Shearer W.T. Green tea polyphenol epigallocatechin gallate binding to CD4 as a model for the inhibition of HIV-1-gp120 binding to CD4+ T cells. J. Allergy Clin. Immun. 113 2 (2004) S256
5. Scott B.C., Butler J., Halliwell B., and Aruoma O.I. Evaluation of the antioxidant actions of ferulic acid and catechins. Free Radical Res. Commun. 19 4 (1993) 241-253
6. Choi Y.B., Kim Y.I., Lee K.S., Kim B.S., and Kim D.J. Protective effect of epigallocatechin gallate on brain damage after transient middle cerebral artery occlusion in rats. Brain Res. 1019 1-2 (2004) 47-54
7. Zhu A., Wang X., and Guo Z. Study of tea polyphenol as a reversal agent for carcinoma cell lines' multidrug resistance (study of TP as a MDR reversal agent). Nucl. Med. Biol. 28 6 (2001) 735-740
8. Bhattacharyya A., Mandal D., Lahiry L., Sa G., and Das T. Black tea protects immunocytes from tumor-induced apoptosis by changing Bcl-2/Bax ratio. Cancer Lett. 209 2 (2004) 147-154
9. Apostolides Z., and Weisburger J.H. Screening of tea clones for inhibition of PhIP mutagenicity. Mutat. Res. 326 2 (1995) 219-225
10. Nakagawa T., and Yokozawa T. Direct scavenging of nitric oxide and superoxide by green tea. Food Chem. Toxicol. 40 (2002) 1745-1750
11. Geetha T., Garg A., Chopra K., and Kaur I.P. Delineation of antimutagenic activity of catechin, epicatechin and green tea extract. Mutat. Res. 556 1-2 (2004) 65-74
12. Hanasaki Y., Ogawa S., and Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radical Bio. Med. 16 6 (1994) 845-850
13. Katiyar S.K., Agarwal R., and Mukhtar H. Inhibition of spontaneous and photo-enhanced lipid peroxidation in mouse epidermal microsomes by epicatechin derivatives from green tea. Cancer Lett. 79 1 (1994) 61-66
14. Terao J., Piskulaand M., and Yao Q. Protective effect of Epicatechin, epicatechin gallate, and quercetin on lipid peroxidation in phospholipid bilayers. Arch. Biochem. Biophys. 308 1 (1994) 278-284
15. Cai Y., Ma L., Hou L., Zhou B., Yang L., and Liu Z. Antioxidant effects of green tea polyphenols on free radical initiated peroxidation of rat liver microsomes. Chem. Phys. Lipids 120 (2002) 109-117
16. Valls-Bellés V., González P., and Muñiz P. Epicatechin effect on oxidative damage induced by tert-BOOH in isolated hepatocytes of fasted rats. Proc. Biochem. 39 (2004) 1525-1531
17. Sambrook K., Fritsch J., and Maniatis T. Molecular Cloning: a Laboratory Manual. second ed. 1 (1989), Cold Spring Harbour Laboratory Press, New York pp. 6.3-6.17
18. Maurya D.K., Salvi V.P., and Narr C.K.K. Radioprotection of DNA by ferrulic acid under in vitro and in vivo conditions. Molec. Cell. Biochem. 280 (2005) 200-217
19. Singh N.P. Microgels for estimation of DNA strand breaks, DNA-protein cross links and apoptosis. Mutat. Res. 455 (2000) 111-127
20. Nair C.K.K., Salvi V., Kagiya T.V., and Rajagopalan R. Relevance of radioprotectors in radiotherapy: studies with tocopherol monoglucoside. J. Environ. Pathol. Toxicol. Oncol. 23-2 (2004) 153-160
21. Gandhi N.M., and Nair C.K.K. Prptection of DNA and membrane from gamma-radiation induced damage by gallic acid. Mol. Cell. Biochem. 278 (2005) 111-117
22. Konca K., Lankoff A., Banasik A., Lisowska H., Kuszewski T., Gozdz S., Koza Z., and Wojcik A. Across platform public domain PC image analysis program for the comet assay. Mutat. Res. 534 (2003) 15-20
23. Carlson J.R., Bauer B.A., Vincent A., Limburg P.J., and Wilson T. Reading the tea leaves: anticarcinogenic properties of (-)epigallocatechin-3-gallate. Mayo Clin. Proc. 82 6 (2007) 723-732
24. Katiyar S.K., and Mukhtar H. Tea antioxidants in cancer chemoprevention. J. Cell Biochem. 27 (1997) 59-67
25. Katiyar S.K., Afaq F., Azizuddin K., and Mukhtar H. Inhibition of UV-induced oxidative stress-mediated phosphorylation of mitogen activated protein kinase signaling pathways in cultured human epidermal keratinocytes by green tea polyphenol (-)-epigallocatechin-3-gallate. Toxicol. Appl. Pharmacol. 176 (2001) 110-117
26. Stuart E.C., Scandlyn M.J., and Rosengrn R.J. Role of epigallocatechin gallate (EGCG) in treatment of breast and prostate cancer. Life sci. 79 (2006) 2329-2336
27. Yamamoto T., Staples J., Wataha J., Lewis J., Lockwood P., Schoenlein P., Rao S., Osaki T., Dickinson D., Kamatani T., Schuster G., and Hsu S. Protective effects of EGCG on salivary gland cells treated with gamma-radiation or cis-platin(II) diamine dichloride. Anticancer Res. 24 (2004) 3065-3074
28. Yamamoto T., Hsu S., Lewis J., Wataha J., Dickinson D., Singh B., Bollag W.B., Lockwood P., Ueta E., Osaki T., and Schuster G. Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells. J. Harmacol. Exp. Ther. 307 (2003) 230-236
29. Sakagami H., Arakawa H., Maeda M., Satoh K., Kadofuku T., Fukuchi K., and Gomi K. Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants. Anticancer Res. 21 (2001) 2633-2641
30. Basu-Modak S., Gordon M.J., Dobson L.H., Spencer J.P.E., Rice-Evans C., and Tyrrell R.M. Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts. Free Radical Bio. Med. 35 8 (2003) 910-921
31. Mitjans M., Martínez V., Campo J., Abajo C., Lozano C., Torres J.L., and Vinardell M.P. Novel epicatechin derivatives with antioxidant activity modulate interleukin-1β release in lipopolysaccharide-stimulated human blood. Bioorg. Med. Chem. Lett. 14-20 (2004) 5031-5034
32. Kim M.J., Ryu G.R., Kang J.H., Sim S.S., Min do S., Rhie D.J., Yoon S.H., Hahn S.J., Jeong I.K., Hong K.J., Kim M.S., and Jo Y.H. Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kappaB activation. Biochem. Pharmacol. 68 9 (2004) 1775-1785
33. Bo Z., Long-Min W., Li Y., and Zhong-Li L. Evidence for α-tocopherol regeneration reaction of green tea polyphenols in SDS micelles. Free Radical Bio. Med. 38-1 (2005) 78-84
34. Nair C.K.K., Parida D.K., and Nomura T. Radioprotectors in radiotherapy. J. Radiat. Res. 42 (2001) 21-37
35. Lawenda B.D., Smith D.E., Xu L., Niemierko A., Silverstein J.R., Boucher Y., Kashiwagi S., Held K.D., Jain R.K., Loeffler J.S., Eisenberg D.M., and Blumberg J.B. Do the dietary supplements epigallocatechin gallate or vitamin E cause a radiomodifying response on tumors in vivo? A pilot study with murine breast carcinoma. J. Soc. Integr. Oncol. 5 1 (2007) 11-17 Winter