-
1
-
-
52649167708
-
CD4 T cells: Fates, functions, and faults
-
Zhu, J., and W. E. Paul. 2008. CD4 T cells: fates, functions, and faults. Blood 112: 1557-1569.
-
(2008)
Blood
, vol.112
, pp. 1557-1569
-
-
Zhu, J.1
Paul, W.E.2
-
2
-
-
62849090439
-
Cytokine-secreting follicular T cells shape the antibody repertoire
-
Reinhardt, R. L., H.-E. Liang, and R. M. Locksley. 2009. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat. Immunol. 10: 385-393.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 385-393
-
-
Reinhardt, R.L.1
Liang, H.-E.2
Locksley, R.M.3
-
3
-
-
65549134481
-
T follicular helper cells differentiate from Th2 cells in response to helminth antigens
-
Zaretsky, A. G., J. J. Taylor, I. L. King, F. A. Marshall, M. Mohrs, and E. J. Pearce. 2009. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J. Exp. Med. 206: 991-999.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 991-999
-
-
Zaretsky, A.G.1
Taylor, J.J.2
King, I.L.3
Marshall, F.A.4
Mohrs, M.5
Pearce, E.J.6
-
4
-
-
65549114338
-
+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
-
+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J. Exp. Med. 206: 1001-1007.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1001-1007
-
-
King, I.L.1
Mohrs, M.2
-
5
-
-
13144302865
-
Molecular and cellular pathogenesis of X-linked lymphoproliferative disease
-
Nichols, K. E., C. S. Ma, J. L. Cannons, P. L. Schwartzberg, and S. G. Tangye. 2005. Molecular and cellular pathogenesis of X-linked lymphoproliferative disease. Immunol. Rev. 203: 180-199.
-
(2005)
Immunol. Rev.
, vol.203
, pp. 180-199
-
-
Nichols, K.E.1
Ma, C.S.2
Cannons, J.L.3
Schwartzberg, P.L.4
Tangye, S.G.5
-
6
-
-
43849103008
-
The SLAM and SAP gene families control innate and adaptive immune responses
-
Calpe, S., N. Wang, X. Romero, S. B. Berger, A. Lanyi, P. Engel, and C. Terhorst. 2008. The SLAM and SAP gene families control innate and adaptive immune responses. Adv. Immunol. 97: 177-250.
-
(2008)
Adv. Immunol.
, vol.97
, pp. 177-250
-
-
Calpe, S.1
Wang, N.2
Romero, X.3
Berger, S.B.4
Lanyi, A.5
Engel, P.6
Terhorst, C.7
-
7
-
-
8544229946
-
SAP regulates T(H)2 differentiation and PKC-θ-mediated activation of NF-kappaB1
-
Cannons, J. L., L. J. Yu, B. Hill, L. A. Mijares, D. Dombroski, K. E. Nichols, A. Antonellis, G. A. Koretzky, K. Gardner, and P. L. Schwartzberg. 2004. SAP regulates T(H)2 differentiation and PKC-θ-mediated activation of NF-kappaB1. Immunity 21: 693-706.
-
(2004)
Immunity
, vol.21
, pp. 693-706
-
-
Cannons, J.L.1
Yu, L.J.2
Hill, B.3
Mijares, L.A.4
Dombroski, D.5
Nichols, K.E.6
Antonellis, A.7
Koretzky, G.A.8
Gardner, K.9
Schwartzberg, P.L.10
-
8
-
-
2442445760
-
Molecular dissection of 2B4 signaling: Implications for signal transduction by SLAM-related receptors
-
Chen, R., F. Relouzat, R. Roncagalli, A. Aoukaty, R. Tan, S. Latour, and A. Veillette. 2004. Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors. Mol. Cell. Biol. 24: 5144-5156.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5144-5156
-
-
Chen, R.1
Relouzat, F.2
Roncagalli, R.3
Aoukaty, A.4
Tan, R.5
Latour, S.6
Veillette, A.7
-
9
-
-
0034889004
-
Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product
-
Latour, S., G. Gish, C. D. Helgason, R. K. Humphries, T. Pawson, and A. Veillette. 2001. Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product. Nat. Immunol. 2: 681-690.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 681-690
-
-
Latour, S.1
Gish, G.2
Helgason, C.D.3
Humphries, R.K.4
Pawson, T.5
Veillette, A.6
-
10
-
-
50349103010
-
Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity
-
Zhong, M.-C., and A. Veillette. 2008. Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity. J. Biol. Chem. 283: 19255-19264.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19255-19264
-
-
Zhong, M.-C.1
Veillette, A.2
-
11
-
-
0035340798
-
CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A
-
Shlapatska, L. M., S. V. Mikhalap, A. G. Berdova, O. M. Zelensky, T. J. Yun, K. E. Nichols, E. A. Clark, and S. P. Sidorenko. 2001. CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. J. Immunol. 166: 5480-5487.
-
(2001)
J. Immunol.
, vol.166
, pp. 5480-5487
-
-
Shlapatska, L.M.1
Mikhalap, S.V.2
Berdova, A.G.3
Zelensky, O.M.4
Yun, T.J.5
Nichols, K.E.6
Clark, E.A.7
Sidorenko, S.P.8
-
12
-
-
33749243738
-
The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation
-
Gu, C., S. G. Tangye, X. Sun, Y. Luo, Z. Lin, and J. Wu. 2006. The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation. Proc. Natl. Acad. Sci. USA 103: 14447-14452.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14447-14452
-
-
Gu, C.1
Tangye, S.G.2
Sun, X.3
Luo, Y.4
Lin, Z.5
Wu, J.6
-
13
-
-
56949098139
-
The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation
-
Li, C., D. Schibli, and S. S.-C. Li. 2009. The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation. Cell. Signal. 21: 111-119.
-
(2009)
Cell. Signal.
, vol.21
, pp. 111-119
-
-
Li, C.1
Schibli, D.2
Li, S.S.-C.3
-
14
-
-
0032190081
-
The X-linked lymphoproliferative- Disease gene product SAP regulates signals induced through the coreceptor SLAM
-
Sayos, J., C. Wu, M. Morra, N. Wang, X. Zhang, D. Allen, S. van Schaik, L. Notarangelo, R. Geha, M. G. Roncarolo, et al. 1998. The X-linked lymphoproliferative- disease gene product SAP regulates signals induced through the coreceptor SLAM. Nature 395: 462-469.
-
(1998)
Nature
, vol.395
, pp. 462-469
-
-
Sayos, J.1
Wu, C.2
Morra, M.3
Wang, N.4
Zhang, X.5
Allen, D.6
Van Schaik, S.7
Notarangelo, L.8
Geha, R.9
Roncarolo, M.G.10
-
15
-
-
0035912823
-
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP
-
Czar, M. J., E. N. Kersh, L. A. Mijares, G. Lanier, J. Lewis, G. Yap, A. Chen, A. Sher, C. S. Duckett, R. Ahmed, and P. L. Schwartzberg. 2001. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc. Natl. Acad. Sci. USA 98: 7449-7454.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7449-7454
-
-
Czar, M.J.1
Kersh, E.N.2
Mijares, L.A.3
Lanier, G.4
Lewis, J.5
Yap, G.6
Chen, A.7
Sher, A.8
Duckett, C.S.9
Ahmed, R.10
Schwartzberg, P.L.11
-
16
-
-
8444231176
-
Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation
-
Davidson, D., X. Shi, S. Zhang, H. Wang, M. Nemer, N. Ono, S. Ohno, Y. Yanagi, and A. Veillette. 2004. Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation. Immunity 21: 707-717.
-
(2004)
Immunity
, vol.21
, pp. 707-717
-
-
Davidson, D.1
Shi, X.2
Zhang, S.3
Wang, H.4
Nemer, M.5
Ono, N.6
Ohno, S.7
Yanagi, Y.8
Veillette, A.9
-
17
-
-
2442466916
-
The cell surface receptor SLAM controls T cell and macrophage functions
-
Wang, N., A. Satoskar, W. Faubion, D. Howie, S. Okamoto, S. Feske, C. Gullo, K. Clarke, M. R. Sosa, A. H. Sharpe, and C. Terhorst. 2004. The cell surface receptor SLAM controls T cell and macrophage functions. J. Exp. Med. 199: 1255-1264.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1255-1264
-
-
Wang, N.1
Satoskar, A.2
Faubion, W.3
Howie, D.4
Okamoto, S.5
Feske, S.6
Gullo, C.7
Clarke, K.8
Sosa, M.R.9
Sharpe, A.H.10
Terhorst, C.11
-
18
-
-
0035350808
-
H2 cells
-
H2 cells. Nat. Immunol. 2: 410-414.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 410-414
-
-
Wu, C.1
Nguyen, K.B.2
Pien, G.C.3
Wang, N.4
Gullo, C.5
Howie, D.6
Sosa, M.R.7
Edwards, M.J.8
Borrow, P.9
Satoskar, A.R.10
-
19
-
-
33745032268
-
SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation
-
Cannons, J. L., L. J. Yu, D. Jankovic, S. Crotty, R. Horai, M. Kirby, S. Anderson, A. W. Cheever, A. Sher, and P. L. Schwartzberg. 2006. SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. J. Exp. Med. 203: 1551-1565.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1551-1565
-
-
Cannons, J.L.1
Yu, L.J.2
Jankovic, D.3
Crotty, S.4
Horai, R.5
Kirby, M.6
Anderson, S.7
Cheever, A.W.8
Sher, A.9
Schwartzberg, P.L.10
-
20
-
-
0037448564
-
SAP is required for generating long-term humoral immunity
-
Crotty, S., E. N. Kersh, J. Cannons, P. L. Schwartzberg, and R. Ahmed. 2003. SAP is required for generating long-term humoral immunity. Nature 421: 282-287.
-
(2003)
Nature
, vol.421
, pp. 282-287
-
-
Crotty, S.1
Kersh, E.N.2
Cannons, J.3
Schwartzberg, P.L.4
Ahmed, R.5
-
21
-
-
3242798909
-
SH2D1A regulates T-dependent humoral autoimmunity
-
Hron, J. D., L. Caplan, A. J. Gerth, P. L. Schwartzberg, and S. L. Peng. 2004. SH2D1A regulates T-dependent humoral autoimmunity. J. Exp. Med. 200: 261-266.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 261-266
-
-
Hron, J.D.1
Caplan, L.2
Gerth, A.J.3
Schwartzberg, P.L.4
Peng, S.L.5
-
22
-
-
20144389612
-
Defective B cell responses in the absence of SH2D1A
-
Morra, M., R. A. Barrington, A. C. Abadia-Molina, S. Okamoto, A. Julien, C. Gullo, A. Kalsy, M. J. Edwards, G. Chen, R. Spolski, et al. 2005. Defective B cell responses in the absence of SH2D1A. Proc. Natl. Acad. Sci. USA 102: 4819-4823.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4819-4823
-
-
Morra, M.1
Barrington, R.A.2
Abadia-Molina, A.C.3
Okamoto, S.4
Julien, A.5
Gullo, C.6
Kalsy, A.7
Edwards, M.J.8
Chen, G.9
Spolski, R.10
-
23
-
-
39549088092
-
SAP expression in T cells, not in B cells, is required for humoral immunity
-
Veillette, A., S. Zhang, X. Shi, Z. Dong, D. Davidson, and M.-C. Zhong. 2008. SAP expression in T cells, not in B cells, is required for humoral immunity. Proc. Natl. Acad. Sci. USA 105: 1273-1278.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1273-1278
-
-
Veillette, A.1
Zhang, S.2
Shi, X.3
Dong, Z.4
Davidson, D.5
Zhong, M.-C.6
-
24
-
-
53649107278
-
SAP-controlled T-B cell interactions underlie germinal centre formation
-
Qi, H., J. L. Cannons, F. Klauschen, P. L. Schwartzberg, and R. N. Germain. 2008. SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 455: 764-769.
-
(2008)
Nature
, vol.455
, pp. 764-769
-
-
Qi, H.1
Cannons, J.L.2
Klauschen, F.3
Schwartzberg, P.L.4
Germain, R.N.5
-
25
-
-
76949091588
-
Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84
-
Cannons, J. L., H. Qi, K. T. Lu, M. Dutta, J. Gomez-Rodriguez, J. Cheng, E. K. Wakeland, R. N. Germain, and P. L. Schwartzberg. 2010. Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity 32: 253-265.
-
(2010)
Immunity
, vol.32
, pp. 253-265
-
-
Cannons, J.L.1
Qi, H.2
Lu, K.T.3
Dutta, M.4
Gomez-Rodriguez, J.5
Cheng, J.6
Wakeland, E.K.7
Germain, R.N.8
Schwartzberg, P.L.9
-
26
-
-
63449096041
-
Follicular helper T cells are required for systemic autoimmunity
-
Linterman, M. A., R. J. Rigby, R. K. Wong, D. Yu, R. Brink, J. L. Cannons, P. L. Schwartzberg, M. C. Cook, G. D. Walters, and C. G. Vinuesa. 2009. Follicular helper T cells are required for systemic autoimmunity. J. Exp. Med. 206: 561-576.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 561-576
-
-
Linterman, M.A.1
Rigby, R.J.2
Wong, R.K.3
Yu, D.4
Brink, R.5
Cannons, J.L.6
Schwartzberg, P.L.7
Cook, M.C.8
Walters, G.D.9
Vinuesa, C.G.10
-
27
-
-
33846228857
-
SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase
-
McCausland, M. M., I. Yusuf, H. Tran, N. Ono, Y. Yanagi, and S. Crotty. 2007. SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase. J. Immunol. 178: 817-828.
-
(2007)
J. Immunol.
, vol.178
, pp. 817-828
-
-
McCausland, M.M.1
Yusuf, I.2
Tran, H.3
Ono, N.4
Yanagi, Y.5
Crotty, S.6
-
28
-
-
3242790172
-
Protein kinase C θ is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
-
Marsland, B. J., T. J. Soos, G. Späth, D. R. Littman, and M. Kopf. 2004. Protein kinase C θ is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J. Exp. Med. 200: 181-189.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 181-189
-
-
Marsland, B.J.1
Soos, T.J.2
Späth, G.3
Littman, D.R.4
Kopf, M.5
-
29
-
-
8444243253
-
Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C θ
-
Salek-Ardakani, S., T. So, B. S. Halteman, A. Altman, and M. Croft. 2004. Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C θ. J. Immunol. 173: 6440-6447.
-
(2004)
J. Immunol.
, vol.173
, pp. 6440-6447
-
-
Salek-Ardakani, S.1
So, T.2
Halteman, B.S.3
Altman, A.4
Croft, M.5
-
30
-
-
18844473151
-
PKC-θ is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes
-
Sun, Z., C. W. Arendt, W. Ellmeier, E. M. Schaeffer, M. J. Sunshine, L. Gandhi, J. Annes, D. Petrzilka, A. Kupfer, P. L. Schwartzberg, and D. R. Littman. 2000. PKC-θ is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 404: 402-407.
-
(2000)
Nature
, vol.404
, pp. 402-407
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
Schaeffer, E.M.4
Sunshine, M.J.5
Gandhi, L.6
Annes, J.7
Petrzilka, D.8
Kupfer, A.9
Schwartzberg, P.L.10
Littman, D.R.11
-
31
-
-
34249013684
-
Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse
-
Sims, T. N., T. J. Soos, H. S. Xenias, B. Dubin-Thaler, J. M. Hofman, J. C. Waite, T. O. Cameron, V. K. Thomas, R. Varma, C. H. Wiggins, et al. 2007. Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse. Cell 129: 773-785.
-
(2007)
Cell
, vol.129
, pp. 773-785
-
-
Sims, T.N.1
Soos, T.J.2
Xenias, H.S.3
Dubin-Thaler, B.4
Hofman, J.M.5
Waite, J.C.6
Cameron, T.O.7
Thomas, V.K.8
Varma, R.9
Wiggins, C.H.10
-
32
-
-
0027239842
-
IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression
-
Ding, L., P. S. Linsley, L. Y. Huang, R. N. Germain, and E. M. Shevach. 1993. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J. Immunol. 151: 1224-1234.
-
(1993)
J. Immunol.
, vol.151
, pp. 1224-1234
-
-
Ding, L.1
Linsley, P.S.2
Huang, L.Y.3
Germain, R.N.4
Shevach, E.M.5
-
33
-
-
0034952689
-
Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family
-
Lewis, J., L. J. Eiben, D. L. Nelson, J. I. Cohen, K. E. Nichols, H. D. Ochs, L. D. Notarangelo, and C. S. Duckett. 2001. Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family. Clin. Immunol. 100: 15-23.
-
(2001)
Clin. Immunol.
, vol.100
, pp. 15-23
-
-
Lewis, J.1
Eiben, L.J.2
Nelson, D.L.3
Cohen, J.I.4
Nichols, K.E.5
Ochs, H.D.6
Notarangelo, L.D.7
Duckett, C.S.8
-
34
-
-
0035016243
-
Protein kinase C θ is expressed in mast cells and is functionally involved in Fcepsilon receptor I signaling
-
Liu, Y., C. Graham, V. Parravicini, M. J. Brown, J. Rivera, and S. Shaw. 2001. Protein kinase C θ is expressed in mast cells and is functionally involved in Fcepsilon receptor I signaling. J. Leukoc. Biol. 69: 831-840.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 831-840
-
-
Liu, Y.1
Graham, C.2
Parravicini, V.3
Brown, M.J.4
Rivera, J.5
Shaw, S.6
-
35
-
-
0035374476
-
Antigen-induced translocation of PKC-θ to membrane rafts is required for T cell activation
-
Bi, K., Y. Tanaka, N. Coudronniere, K. Sugie, S. Hong, M. J. van Stipdonk, and A. Altman. 2001. Antigen-induced translocation of PKC-θ to membrane rafts is required for T cell activation. Nat. Immunol. 2: 556-563.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 556-563
-
-
Bi, K.1
Tanaka, Y.2
Coudronniere, N.3
Sugie, K.4
Hong, S.5
Van Stipdonk, M.J.6
Altman, A.7
-
36
-
-
27144446657
-
Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion
-
Finkelstein, L. D., Y. Shimizu, and P. L. Schwartzberg. 2005. Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion. J. Immunol. 175: 5923-5930.
-
(2005)
J. Immunol.
, vol.175
, pp. 5923-5930
-
-
Finkelstein, L.D.1
Shimizu, Y.2
Schwartzberg, P.L.3
-
37
-
-
2442477638
-
SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9
-
Simarro, M., A. Lanyi, D. Howie, F. Poy, J. Bruggeman, M. Choi, J. Sumegi, M. J. Eck, and C. Terhorst. 2004. SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9. Int. Immunol. 16: 727-736.
-
(2004)
Int. Immunol.
, vol.16
, pp. 727-736
-
-
Simarro, M.1
Lanyi, A.2
Howie, D.3
Poy, F.4
Bruggeman, J.5
Choi, M.6
Sumegi, J.7
Eck, M.J.8
Terhorst, C.9
-
38
-
-
0037320641
-
SAP couples Fyn to SLAM immune receptors
-
Chan, B., A. Lanyi, H. K. Song, J. Griesbach, M. Simarro-Grande, F. Poy, D. Howie, J. Sumegi, C. Terhorst, and M. J. Eck. 2003. SAP couples Fyn to SLAM immune receptors. Nat. Cell Biol. 5: 155-160.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 155-160
-
-
Chan, B.1
Lanyi, A.2
Song, H.K.3
Griesbach, J.4
Simarro-Grande, M.5
Poy, F.6
Howie, D.7
Sumegi, J.8
Terhorst, C.9
Eck, M.J.10
-
39
-
-
0037322612
-
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation
-
Latour, S., R. Roncagalli, R. Chen, M. Bakinowski, X. Shi, P. L. Schwartzberg, D. Davidson, and A. Veillette. 2003. Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation. Nat. Cell Biol. 5: 149-154.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 149-154
-
-
Latour, S.1
Roncagalli, R.2
Chen, R.3
Bakinowski, M.4
Shi, X.5
Schwartzberg, P.L.6
Davidson, D.7
Veillette, A.8
-
40
-
-
33746568382
-
Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor
-
Chen, R., S. Latour, X. Shi, and A. Veillette. 2006. Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor. Mol. Cell. Biol. 26: 5559-5568.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5559-5568
-
-
Chen, R.1
Latour, S.2
Shi, X.3
Veillette, A.4
-
41
-
-
0346995021
-
Disease-causing SAP mutants are defective in ligand binding and protein folding
-
Li, C., C. Iosef, C. Y. H. Jia, T. Gkourasas, V. K. M. Han, and S. Shun-Cheng Li. 2003. Disease-causing SAP mutants are defective in ligand binding and protein folding. Biochemistry 42: 14885-14892.
-
(2003)
Biochemistry
, vol.42
, pp. 14885-14892
-
-
Li, C.1
Iosef, C.2
Jia, C.Y.H.3
Gkourasas, T.4
Han, V.K.M.5
Li, S.S.-C.6
-
42
-
-
41149167494
-
T-cell fate and function: PKC-θ and beyond
-
Marsland, B. J., and M. Kopf. 2008. T-cell fate and function: PKC-θ and beyond. Trends Immunol. 29: 179-185.
-
(2008)
Trends Immunol.
, vol.29
, pp. 179-185
-
-
Marsland, B.J.1
Kopf, M.2
-
43
-
-
0028799945
-
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells
-
Constant, S., C. Pfeiffer, A. Woodard, T. Pasqualini, and K. Bottomly. 1995. Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells. J. Exp. Med. 182: 1591-1596.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1591-1596
-
-
Constant, S.1
Pfeiffer, C.2
Woodard, A.3
Pasqualini, T.4
Bottomly, K.5
-
45
-
-
25144476332
-
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
-
Yamane, H., J. Zhu, and W. E. Paul. 2005. Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment. J. Exp. Med. 202: 793-804.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 793-804
-
-
Yamane, H.1
Zhu, J.2
Paul, W.E.3
-
46
-
-
0036464688
-
Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation
-
Howie, D., M. Simarro, J. Sayos, M. Guirado, J. Sancho, and C. Terhorst. 2002. Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation. Blood 99: 957-965.
-
(2002)
Blood
, vol.99
, pp. 957-965
-
-
Howie, D.1
Simarro, M.2
Sayos, J.3
Guirado, M.4
Sancho, J.5
Terhorst, C.6
-
47
-
-
70349678683
-
Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency
-
Snow, A. L., R. A. Marsh, S. M. Krummey, P. Roehrs, L. R. Young, K. Zhang, J. v. Hoff, D. Dhar, K. E. Nichols, A. H. Filipovich, et al. 2009. Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. J. Clin. Invest. 119: 2976-2989.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2976-2989
-
-
Snow, A.L.1
Marsh, R.A.2
Krummey, S.M.3
Roehrs, P.4
Young, L.R.5
Zhang, K.6
Hoff, J.V.7
Dhar, D.8
Nichols, K.E.9
Filipovich, A.H.10
-
48
-
-
0026669001
-
Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn
-
Appleby, M. W., J. A. Gross, M. P. Cooke, S. D. Levin, X. Qian, and R. M. Perlmutter. 1992. Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70: 751-763.
-
(1992)
Cell
, vol.70
, pp. 751-763
-
-
Appleby, M.W.1
Gross, J.A.2
Cooke, M.P.3
Levin, S.D.4
Qian, X.5
Perlmutter, R.M.6
-
49
-
-
54049100744
-
+ T cells
-
+ T cells. J. Immunol. 181: 5374-5385.
-
(2008)
J. Immunol.
, vol.181
, pp. 5374-5385
-
-
Mamchak, A.A.1
Sullivan, B.M.2
Hou, B.3
Lee, L.M.4
Gilden, J.K.5
Krummel, M.F.6
Locksley, R.M.7
DeFranco, A.L.8
-
50
-
-
0026612411
-
pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
-
Stein, P. L., H.-M. Lee, S. Rich, and P. Soriano. 1992. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70: 741-750.
-
(1992)
Cell
, vol.70
, pp. 741-750
-
-
Stein, P.L.1
Lee, H.-M.2
Rich, S.3
Soriano, P.4
-
51
-
-
49249128709
-
Fyn regulates the duration of TCR engagement needed for commitment to effector function
-
Filby, A., B. Seddon, J. Kleczkowska, R. Salmond, P. Tomlinson, M. Smida, J. A. Lindquist, B. Schraven, and R. Zamoyska. 2007. Fyn regulates the duration of TCR engagement needed for commitment to effector function. J. Immunol. 179: 4635-4644.
-
(2007)
J. Immunol.
, vol.179
, pp. 4635-4644
-
-
Filby, A.1
Seddon, B.2
Kleczkowska, J.3
Salmond, R.4
Tomlinson, P.5
Smida, M.6
Lindquist, J.A.7
Schraven, B.8
Zamoyska, R.9
-
53
-
-
0032723181
-
The Src family tyrosine kinase Fyn regulates natural killer T cell development
-
Gadue, P., N. Morton, and P. L. Stein. 1999. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J. Exp. Med. 190: 1189-1196.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1189-1196
-
-
Gadue, P.1
Morton, N.2
Stein, P.L.3
-
54
-
-
0037881900
-
Regulation of Fyn through translocation of activated Lck into lipid rafts
-
Filipp, D., J. Zhang, B. L. Leung, A. Shaw, S. D. Levin, A. Veillette, and M. Julius. 2003. Regulation of Fyn through translocation of activated Lck into lipid rafts. J. Exp. Med. 197: 1221-1227.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1221-1227
-
-
Filipp, D.1
Zhang, J.2
Leung, B.L.3
Shaw, A.4
Levin, S.D.5
Veillette, A.6
Julius, M.7
-
55
-
-
6944241415
-
Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling
-
Sugie, K., M.-S. Jeon, and H. M. Grey. 2004. Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling. Proc. Natl. Acad. Sci. USA 101: 14859-14864.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14859-14864
-
-
Sugie, K.1
Jeon, M.-S.2
Grey, H.M.3
-
56
-
-
77955280012
-
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)
-
Yusuf, I., R. Kageyama, L. Monticelli, R. J. Johnston, D. DiToro, K. Hansen, B. Barnett, and S. Crotty. 2010. Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J. Immunol. 185: 190-202.
-
(2010)
J. Immunol.
, vol.185
, pp. 190-202
-
-
Yusuf, I.1
Kageyama, R.2
Monticelli, L.3
Johnston, R.J.4
DiToro, D.5
Hansen, K.6
Barnett, B.7
Crotty, S.8
-
57
-
-
29644441040
-
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- And SAP-deficient mice
-
Graham, D. B., M. P. Bell, M. M. McCausland, C. J. Huntoon, J. van Deursen, W. A. Faubion, S. Crotty, and D. J. McKean. 2006. Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice. J. Immunol. 176: 291-300.
-
(2006)
J. Immunol.
, vol.176
, pp. 291-300
-
-
Graham, D.B.1
Bell, M.P.2
McCausland, M.M.3
Huntoon, C.J.4
Van Deursen, J.5
Faubion, W.A.6
Crotty, S.7
McKean, D.J.8
-
58
-
-
20844439884
-
Cutting edge: The SLAM family receptor Ly108 controls T cell and neutrophil functions
-
Howie, D., F. S. Laroux, M. Morra, A. R. Satoskar, L. E. Rosas, W. A. Faubion, A. Julien, S. Rietdijk, A. J. Coyle, C. Fraser, and C. Terhorst. 2005. Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J. Immunol. 174: 5931-5935.
-
(2005)
J. Immunol.
, vol.174
, pp. 5931-5935
-
-
Howie, D.1
Laroux, F.S.2
Morra, M.3
Satoskar, A.R.4
Rosas, L.E.5
Faubion, W.A.6
Julien, A.7
Rietdijk, S.8
Coyle, A.J.9
Fraser, C.10
Terhorst, C.11
-
59
-
-
36049012716
-
Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development
-
Griewank, K., C. Borowski, S. Rietdijk, N. Wang, A. Julien, D. G. Wei, A. A. Mamchak, C. Terhorst, and A. Bendelac. 2007. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27: 751-762.
-
(2007)
Immunity
, vol.27
, pp. 751-762
-
-
Griewank, K.1
Borowski, C.2
Rietdijk, S.3
Wang, N.4
Julien, A.5
Wei, D.G.6
Mamchak, A.A.7
Terhorst, C.8
Bendelac, A.9
-
60
-
-
1642299050
-
PKCtheta signals activation versus tolerance in vivo
-
Berg-Brown, N. N., M. A. Gronski, R. G. Jones, A. R. Elford, E. K. Deenick, B. Odermatt, D. R. Littman, and P. S. Ohashi. 2004. PKCtheta signals activation versus tolerance in vivo. J. Exp. Med. 199: 743-752.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 743-752
-
-
Berg-Brown, N.N.1
Gronski, M.A.2
Jones, R.G.3
Elford, A.R.4
Deenick, E.K.5
Odermatt, B.6
Littman, D.R.7
Ohashi, P.S.8
-
62
-
-
33845921462
-
The critical role of protein kinase C-u in Fas/Fas ligand-mediated apoptosis
-
Manicassamy, S., and Z. Sun. 2007. The critical role of protein kinase C-u in Fas/Fas ligand-mediated apoptosis. J. Immunol. 178: 312-319.
-
(2007)
J. Immunol.
, vol.178
, pp. 312-319
-
-
Manicassamy, S.1
Sun, Z.2
-
63
-
-
33847345465
-
CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B
-
Saibil, S. D., R. G. Jones, E. K. Deenick, N. Liadis, A. R. Elford, M. G. Vainberg, H. Baerg, J. R. Woodgett, S. Gerondakis, and P. S. Ohashi. 2007. CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. J. Immunol. 178: 2932-2939.
-
(2007)
J. Immunol.
, vol.178
, pp. 2932-2939
-
-
Saibil, S.D.1
Jones, R.G.2
Deenick, E.K.3
Liadis, N.4
Elford, A.R.5
Vainberg, M.G.6
Baerg, H.7
Woodgett, J.R.8
Gerondakis, S.9
Ohashi, P.S.10
-
64
-
-
0035873711
-
Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD
-
Villalba, M., P. Bushway, and A. Altman. 2001. Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD. J. Immunol. 166: 5955-5963.
-
(2001)
J. Immunol.
, vol.166
, pp. 5955-5963
-
-
Villalba, M.1
Bushway, P.2
Altman, A.3
-
65
-
-
0034176032
-
Vav synergizes with protein kinase C u to mediate IL-4 gene expression in response to CD28 costimulation in T cells
-
Hehner, S. P., M. Li-Weber, M. Giaisi, W. Dröge, P. H. Krammer, and M. L. Schmitz. 2000. Vav synergizes with protein kinase C u to mediate IL-4 gene expression in response to CD28 costimulation in T cells. J. Immunol. 164: 3829-3836.
-
(2000)
J. Immunol.
, vol.164
, pp. 3829-3836
-
-
Hehner, S.P.1
Li-Weber, M.2
Giaisi, M.3
Dröge, W.4
Krammer, P.H.5
Schmitz, M.L.6
-
66
-
-
23744484121
-
Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1- Deficient mice
-
Tanaka, Y., T. So, S. Lebedeva, M. Croft, and A. Altman. 2005. Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1- deficient mice. Blood 106: 1286-1295.
-
(2005)
Blood
, vol.106
, pp. 1286-1295
-
-
Tanaka, Y.1
So, T.2
Lebedeva, S.3
Croft, M.4
Altman, A.5
|