SCOPUS 정보 검색 플랫폼

Volumn 46, Issue 44, 2010, Pages 8371-8373

Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

(7) Pacchiano, Fabio a Aggarwal, Mayank b Avvaru, Balendu Sankara b Robbins, Arthur H b Scozzafava, Andrea a McKenna, Robert b Supuran, Claudiu T a

a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE (United States)

b UNIVERSITY OF FLORENCE (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR;

ARTICLE; BINDING KINETICS; CRYSTAL STRUCTURE; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROGEN BOND; HYDROPHOBICITY; SUBSTITUTION REACTION;

EID: 78049375982 PISSN: 13597345 EISSN: None Source Type: Journal
DOI: 10.1039/c0cc02707c Document Type: Article

Times cited : (207)

References (22)

1
- 38849143765
- C. T. Supuran Nat. Rev. Drug Discovery 2008 7 168
- (2008) Nat. Rev. Drug Discovery , vol.7 , pp. 168
- Supuran, C.T.¹

2
- 57649155218
- J. F. Domsic B. S. Avvaru C. U. Kim S. M. Gruner M. Agbandje-McKenna D. N. Silverman R. McKenna J. Biol. Chem. 2008 283 30766
- (2008) J. Biol. Chem. , vol.283 , pp. 30766
- Domsic, J.F.¹ Avvaru, B.S.² Kim, C.U.³ Gruner, S.M.⁴ Agbandje-Mckenna, M.⁵ Silverman, D.N.⁶ McKenna, R.⁷

3
- 0000726701
- D. W. Christianson C. A. Fierke Acc. Chem. Res. 1996 29 331
- (1996) Acc. Chem. Res. , vol.29 , pp. 331
- Christianson, D.W.¹ Fierke, C.A.²

4
- 84889476926
- X-Ray crystallography of CA inhibitors and its importance in drug design in
- ed. C. T. Supuran and J. Y. Winum, Wiley, Hoboken
- V. Alterio, A. Di Fiore, K. D'Ambrosio, C. T. Supuran and G. De Simone, X-Ray crystallography of CA inhibitors and its importance in drug design in Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications, ed., C. T. Supuran, and, J. Y. Winum,, Wiley, Hoboken, 2009, pp. 73-138
- (2009) Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications , pp. 73-138
- Alterio, V.¹ Di Fiore, A.² D'Ambrosio, K.³ Supuran, C.T.⁴ De Simone, G.⁵

5
- 35048900931
- K. Köhler A. Hillebrecht J. Schulze Wischeler A. Innocenti A. Heine C. T. Supuran G. Klebe Angew. Chem., Int. Ed. 2007 46 7697
- (2007) Angew. Chem., Int. Ed. , vol.46 , pp. 7697
- Köhler, K.¹ Hillebrecht, A.² Schulze Wischeler, J.³ Innocenti, A.⁴ Heine, A.⁵ Supuran, C.T.⁶ Klebe, G.⁷

6
- 0024218271
- A. E. Eriksson T. A. Jones A. Liljas Proteins: Struct., Funct., Genet. 1988 4 274
- (1988) Proteins: Struct., Funct., Genet. , vol.4 , pp. 274
- Eriksson, A.E.¹ Jones, T.A.² Liljas, A.³

7
- 72249106865
- C. Temperini A. Scozzafava C. T. Supuran Bioorg. Med. Chem. Lett. 2010 20 474
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 474
- Temperini, C.¹ Scozzafava, A.² Supuran, C.T.³

8
- 0027949918
- S. K. Nair P. A. Ludwig D. W. Christianson J. Am. Chem. Soc. 1994 116 3659
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 3659
- Nair, S.K.¹ Ludwig, P.A.² Christianson, D.W.³

9
- 67749116253
- A. Maresca C. Temperini H. Vu N. B. Pham S. A. Poulsen A. Scozzafava R. J. Quinn C. T. Supuran J. Am. Chem. Soc. 2009 131 3057
- (2009) J. Am. Chem. Soc. , vol.131 , pp. 3057
- Maresca, A.¹ Temperini, C.² Vu, H.³ Pham, N.B.⁴ Poulsen, S.A.⁵ Scozzafava, A.⁶ Quinn, R.J.⁷ Supuran, C.T.⁸

10
- 77955391402
- F. Carta C. Temperini A. Innocenti A. Scozzafava K. Kaila C. T. Supuran J. Med. Chem 2010 53 5511
- (2010) J. Med. Chem , vol.53 , pp. 5511
- Carta, F.¹ Temperini, C.² Innocenti, A.³ Scozzafava, A.⁴ Kaila, K.⁵ Supuran, C.T.⁶

11
- 0032007213
- The synthesis of inhibitors 1-5 was done by reaction of sulfanilamide and the corresponding aryl/alkyl isocyanate as described earlier in C. T. Supuran A. Scozzafava B. C. Jurca M. A. Ilies Eur. J. Med. Chem. 1998 33 83
- (1998) Eur. J. Med. Chem. , vol.33 , pp. 83
- Supuran, C.T.¹ Scozzafava, A.² Jurca, B.C.³ Ilies, M.A.⁴

12
- 77955424033
- B. S. Avvaru J. M. Wagner A. Maresca A. Scozzafava A. H. Robbins C. T. Supuran R. McKenna Bioorg. Med. Chem. Lett. 2010 20 4376
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 4376
- Avvaru, B.S.¹ Wagner, J.M.² Maresca, A.³ Scozzafava, A.⁴ Robbins, A.H.⁵ Supuran, C.T.⁶ McKenna, R.⁷

13
- 77955338487
- J. Wagner B. S. Avvaru A. H. Robbins A. Scozzafava C. T. Supuran R. McKenna Bioorg. Med. Chem. 2010 18 4873
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 4873
- Wagner, J.¹ Avvaru, B.S.² Robbins, A.H.³ Scozzafava, A.⁴ Supuran, C.T.⁵ McKenna, R.⁶

14
- 24744467784
- V. Menchise G. De Simone V. Alterio A. Di Fiore C. Pedone A. Scozzafava C. T. Supuran J. Med. Chem. 2005 48 5721
- (2005) J. Med. Chem. , vol.48 , pp. 5721
- Menchise, V.¹ De Simone, G.² Alterio, V.³ Di Fiore, A.⁴ Pedone, C.⁵ Scozzafava, A.⁶ Supuran, C.T.⁷

15
- 33845353402
- J. Y. Winum C. Temperini K. El Cheikh A. Innocenti D. Vullo S. Ciattini J. L. Montero A. Scozzafava C. T. Supuran J. Med. Chem. 2006 49 7024
- (2006) J. Med. Chem. , vol.49 , pp. 7024
- Winum, J.Y.¹ Temperini, C.² El Cheikh, K.³ Innocenti, A.⁴ Vullo, D.⁵ Ciattini, S.⁶ Montero, J.L.⁷ Scozzafava, A.⁸ Supuran, C.T.⁹

16
- 0031059866
- Z. Otwinowski W. Minor Methods Enzymol 1997 276 307
- (1997) Methods Enzymol , vol.276 , pp. 307
- Otwinowski, Z.¹ Minor, W.²

17
- 33947414441
- S. Z. Fisher C. M. Maupin M. Budayova-Spano L. Govindasamy C. K. Tu M. Agbandje-McKenna D. N. Silverman G. A. Voth R. McKenna Biochemistry 2007 42 2930
- (2007) Biochemistry , vol.42 , pp. 2930
- Fisher, S.Z.¹ Maupin, C.M.² Budayova-Spano, M.³ Govindasamy, L.⁴ Tu, C.K.⁵ Agbandje-Mckenna, M.⁶ Silverman, D.N.⁷ Voth, G.A.⁸ McKenna, R.⁹

18
- 76449098262
- P. D. Adams P. V. Afonine G. Bunkóczi V. B. Chen I. W. Davis N. Echols J. J. Headd L.-W. Hung G. J. Kapral R. W. Grosse-Kunstleve A. J. McCoy N. W. Moriarty R. Oeffner R. J. Read D. C. Richardson J. S. Richardson T. C. Terwilliger P. H. Zwart Acta Crystallogr. 2010 D66 213
- (2010) Acta Crystallogr. , vol.66 , pp. 213
- Adams, P.D.¹ Afonine, P.V.² Bunkóczi, G.³ Chen, V.B.⁴ Davis, I.W.⁵ Echols, N.⁶ Headd, J.J.⁷ Hung, L.-W.⁸ Kapral, G.J.⁹ Grosse-Kunstleve, R.W.¹⁰ McCoy, A.J.¹¹ Moriarty, N.W.¹² Oeffner, R.¹³ Read, R.J.¹⁴ Richardson, D.C.¹⁵ Richardson, J.S.¹⁶ Terwilliger, T.C.¹⁷ Zwart, P.H.¹⁸

19
- 7544226311
- A. W. Schuettelkopf D. M. F. van Aalten Acta Crystallogr. 2004 D60 1355
- (2004) Acta Crystallogr. , vol.60 , pp. 1355
- Schuettelkopf, A.W.¹ Van Aalten, D.M.F.²

20
- 13244281317
- P. Emsley K. Cowtan Acta Crystallogr. 2004 60 2126
- (2004) Acta Crystallogr. , vol.60 , pp. 2126
- Emsley, P.¹ Cowtan, K.²

21
- 0000243829
- R. A. Laskowski M. W. MacArthur D. S. Moss J. M. Thornton J. Appl. Crystallogr. 1993 26 283
- (1993) J. Appl. Crystallogr. , vol.26 , pp. 283
- Laskowski, R.A.¹ MacArthur, M.W.² Moss, D.S.³ Thornton, J.M.⁴

22
- 0015239422
- R. G. Khalifah J. Biol. Chem. 1971 246 2561
- (1971) J. Biol. Chem. , vol.246 , pp. 2561
- Khalifah, R.G.¹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.