메뉴 건너뛰기




Volumn 484, Issue C, 2010, Pages 413-443

In Vitro and In Vivo Assessment of Mu opioid receptor constitutive activity

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; MU OPIATE RECEPTOR; NALOXONE; OPIATE; OPIATE ANTAGONIST;

EID: 78049320270     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-381298-8.00021-6     Document Type: Chapter
Times cited : (6)

References (38)
  • 1
    • 59949102887 scopus 로고    scopus 로고
    • Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors
    • Aloyo V.J., Berg K.A., Spampinato U., Clarke W.P., Harvey J.A. Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors. Pharmacol. Ther. 2009, 121:160-173.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 160-173
    • Aloyo, V.J.1    Berg, K.A.2    Spampinato, U.3    Clarke, W.P.4    Harvey, J.A.5
  • 2
    • 0029130047 scopus 로고
    • Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells
    • Arden J.R., Segredo V., Wang Z., Lameh J., Sadee W. Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells. J. Neurochem. 1995, 65:1636-1645.
    • (1995) J. Neurochem. , vol.65 , pp. 1636-1645
    • Arden, J.R.1    Segredo, V.2    Wang, Z.3    Lameh, J.4    Sadee, W.5
  • 3
    • 0030439407 scopus 로고    scopus 로고
    • Effects of naloxone and D-Phe-Cys-Try-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice
    • Bilsky E.J., Bernstein R.N., Wang Z., Sadée W., Porreca F. Effects of naloxone and D-Phe-Cys-Try-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice. J. Pharmacol. Exp. Ther. 1996, 277:484-490.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 484-490
    • Bilsky, E.J.1    Bernstein, R.N.2    Wang, Z.3    Sadée, W.4    Porreca, F.5
  • 4
    • 0031000795 scopus 로고    scopus 로고
    • Acute and chronic effects of opioids on delta and mu receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes
    • Breivogel C.S., Selley D.E., Childers S.R. Acute and chronic effects of opioids on delta and mu receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes. J. Neurochem. 1997, 68:1462-1472.
    • (1997) J. Neurochem. , vol.68 , pp. 1462-1472
    • Breivogel, C.S.1    Selley, D.E.2    Childers, S.R.3
  • 5
    • 1642493743 scopus 로고    scopus 로고
    • Precipitated opioid withdrawal across acute physical dependence induction methods
    • Compton P., Miotto K., Elashoff D. Precipitated opioid withdrawal across acute physical dependence induction methods. Pharmacol. Biochem. Behav. 2004, 77:263-268.
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 263-268
    • Compton, P.1    Miotto, K.2    Elashoff, D.3
  • 6
    • 0001169515 scopus 로고
    • Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins
    • Costa T., Herz A. Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proc. Natl. Acad. Sci. 1989, 86:7321-7325.
    • (1989) Proc. Natl. Acad. Sci. , vol.86 , pp. 7321-7325
    • Costa, T.1    Herz, A.2
  • 8
    • 0028123538 scopus 로고
    • Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat
    • Gold L.H., Stinus L., Inturrisi C.E., Koob G.F. Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat. Eur. J. Pharmacol. 1994, 253:45-51.
    • (1994) Eur. J. Pharmacol. , vol.253 , pp. 45-51
    • Gold, L.H.1    Stinus, L.2    Inturrisi, C.E.3    Koob, G.F.4
  • 9
    • 0034753012 scopus 로고    scopus 로고
    • Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells
    • Gray J.A., Sheffler D.J., Bhatnagar A., Woods J.A., Hufeisen S.J., Benovic J.L., Roth B.L. Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells. Mol. Pharmacol. 2001, 60:1020-1030.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1020-1030
    • Gray, J.A.1    Sheffler, D.J.2    Bhatnagar, A.3    Woods, J.A.4    Hufeisen, S.J.5    Benovic, J.L.6    Roth, B.L.7
  • 11
    • 84942517534 scopus 로고    scopus 로고
    • Comparison of antagonist potency to evoke an acute withdrawal stimulus 4h after pretreatment with morphine in rats
    • Hazel K.D., Fluck J., Jones N.T., Evola M., Young A.M. Comparison of antagonist potency to evoke an acute withdrawal stimulus 4h after pretreatment with morphine in rats. FASEB J. 2008, 22:712.
    • (2008) FASEB J. , vol.22 , pp. 712
    • Hazel, K.D.1    Fluck, J.2    Jones, N.T.3    Evola, M.4    Young, A.M.5
  • 12
    • 0033578005 scopus 로고    scopus 로고
    • G-protein-coupled receptor heterodimerization modulates receptor function
    • Jordan B.A., Devi L.A. G-protein-coupled receptor heterodimerization modulates receptor function. Nature 1999, 399:697-700.
    • (1999) Nature , vol.399 , pp. 697-700
    • Jordan, B.A.1    Devi, L.A.2
  • 13
    • 0037146707 scopus 로고    scopus 로고
    • Naloxone-precipitated withdrawal jumping in 11 inbred mouse strains: Evidence for common genetic mechanisms in acute and chronic morphine physical dependence
    • Kest B., Palmese C.A., Hopkins E., Adler M., Juni A., Mogil J.S. Naloxone-precipitated withdrawal jumping in 11 inbred mouse strains: Evidence for common genetic mechanisms in acute and chronic morphine physical dependence. Neuroscience 2002, 115:463-469.
    • (2002) Neuroscience , vol.115 , pp. 463-469
    • Kest, B.1    Palmese, C.A.2    Hopkins, E.3    Adler, M.4    Juni, A.5    Mogil, J.S.6
  • 14
    • 0016106498 scopus 로고
    • A neuroblastoma times glioma hybrid cell line with morphine receptors
    • Klee W.A., Nirenberg M. A neuroblastoma times glioma hybrid cell line with morphine receptors. Proc. Natl. Acad. Sci. USA 1974, 71:3474-3477.
    • (1974) Proc. Natl. Acad. Sci. USA , vol.71 , pp. 3474-3477
    • Klee, W.A.1    Nirenberg, M.2
  • 15
    • 0034955327 scopus 로고    scopus 로고
    • Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment
    • Liu J.G., Prather P.L. Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment. Mol. Pharmacol. 2001, 60:53-62.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 53-62
    • Liu, J.G.1    Prather, P.L.2
  • 16
    • 78049285545 scopus 로고    scopus 로고
    • Updating the chemistry and biology of cannabinoid CB2 receptor-specific inverse agonists
    • Lunn C.A. Updating the chemistry and biology of cannabinoid CB2 receptor-specific inverse agonists. Curr. Top. Med. Chem. 2010, 10:768-778.
    • (2010) Curr. Top. Med. Chem. , vol.10 , pp. 768-778
    • Lunn, C.A.1
  • 17
    • 0025143320 scopus 로고
    • A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid
    • Nordstedt C., Fredholm B.B. A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid. Anal. Biochem. 1990, 189:231-234.
    • (1990) Anal. Biochem. , vol.189 , pp. 231-234
    • Nordstedt, C.1    Fredholm, B.B.2
  • 19
    • 19444361830 scopus 로고    scopus 로고
    • In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice
    • Raehal K.M., Lowery J.J., Bhamidipati C.M., Paolino R.M., Blair J.R., Wang D., Sadee W., Bilsky E.J. In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice. J. Pharmacol. Exp. Ther. 2005, 313:1150-1162.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 1150-1162
    • Raehal, K.M.1    Lowery, J.J.2    Bhamidipati, C.M.3    Paolino, R.M.4    Blair, J.R.5    Wang, D.6    Sadee, W.7    Bilsky, E.J.8
  • 20
    • 12844281159 scopus 로고    scopus 로고
    • Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities
    • Sadée W., Wang D., Bilsky E.J. Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities. Life Sci. 2005, 76:1427-1437.
    • (2005) Life Sci. , vol.76 , pp. 1427-1437
    • Sadée, W.1    Wang, D.2    Bilsky, E.J.3
  • 22
    • 67651048971 scopus 로고    scopus 로고
    • The relative potency of inverse agonists and a neutral opioid antagonist in precipitated withdrawal
    • Sirohi S., Dighe S.V., Madia P.A., Yoburn B.C. The relative potency of inverse agonists and a neutral opioid antagonist in precipitated withdrawal. J. Pharmacol. Exp. Ther. 2009, 330:513-519.
    • (2009) J. Pharmacol. Exp. Ther. , vol.330 , pp. 513-519
    • Sirohi, S.1    Dighe, S.V.2    Madia, P.A.3    Yoburn, B.C.4
  • 23
    • 0030948994 scopus 로고    scopus 로고
    • G proteins and opioid receptor-mediated signaling
    • Standifer K.M., Pasternak G.W. G proteins and opioid receptor-mediated signaling. Cell. Signal. 1997, 9:237-248.
    • (1997) Cell. Signal. , vol.9 , pp. 237-248
    • Standifer, K.M.1    Pasternak, G.W.2
  • 25
    • 0028986870 scopus 로고
    • Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells
    • Traynor J.R., Nahorski S.R. Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells. Mol. Pharmacol. 1995, 47:848-854.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 848-854
    • Traynor, J.R.1    Nahorski, S.R.2
  • 26
    • 0036138168 scopus 로고    scopus 로고
    • Relationship between rate and extent of G protein activation: Comparison between full and partial opioid agonists
    • Traynor J.R., Clark M.J., Remmers A.E. Relationship between rate and extent of G protein activation: Comparison between full and partial opioid agonists. J. Pharmacol. Exp. Ther. 2002, 300:157-161.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 157-161
    • Traynor, J.R.1    Clark, M.J.2    Remmers, A.E.3
  • 28
    • 0028172305 scopus 로고
    • In vivo pA2 analysis of naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats
    • Walker E.A., Makhay M.M., House J.D., Young A.M. In vivo pA2 analysis of naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats. J. Pharmacol. Exp. Ther. 1994, 271:959-968.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 959-968
    • Walker, E.A.1    Makhay, M.M.2    House, J.D.3    Young, A.M.4
  • 29
    • 0028299699 scopus 로고
    • Constitutive mu opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence
    • Wang Z., Bilsky E.J., Porreca F., Sadee W. Constitutive mu opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence. Life Sci. 1994, 54:PL339-PL350.
    • (1994) Life Sci. , vol.54
    • Wang, Z.1    Bilsky, E.J.2    Porreca, F.3    Sadee, W.4
  • 30
    • 0034972443 scopus 로고    scopus 로고
    • Inverse agonists and neutral antagonists at mu opioid receptor (MOR): Possible role of basal receptor signaling in narcotic dependence
    • Wang D., Raehal K.M., Bilsky E.J., Sadee W. Inverse agonists and neutral antagonists at mu opioid receptor (MOR): Possible role of basal receptor signaling in narcotic dependence. J. Neurochem. 2001, 77:1590-1600.
    • (2001) J. Neurochem. , vol.77 , pp. 1590-1600
    • Wang, D.1    Raehal, K.M.2    Bilsky, E.J.3    Sadee, W.4
  • 32
    • 34247234605 scopus 로고    scopus 로고
    • Different effects of opioid antagonists on mu, delta-, and kappa-opioid receptors with and without agonist pretreatment
    • Wang D., Sun X., Sadée W. Different effects of opioid antagonists on mu, delta-, and kappa-opioid receptors with and without agonist pretreatment. J. Pharmacol. Exp. Ther. 2007, 321:544-552.
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 544-552
    • Wang, D.1    Sun, X.2    Sadée, W.3
  • 34
    • 0035138995 scopus 로고    scopus 로고
    • Cellular and synaptic adaptations mediating opioid dependence
    • Williams J.T., Christie M.J., Manzoni O. Cellular and synaptic adaptations mediating opioid dependence. Physiol. Rev. 2001, 81:299-343.
    • (2001) Physiol. Rev. , vol.81 , pp. 299-343
    • Williams, J.T.1    Christie, M.J.2    Manzoni, O.3
  • 35
    • 0026612135 scopus 로고
    • Use of in vivo apparent pA2 analysis in assessment of opioid abuse liability
    • Woods J.H., Winger G., France C.P. Use of in vivo apparent pA2 analysis in assessment of opioid abuse liability. Trends Pharmacol. Sci. 1992, 13:282-286.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 282-286
    • Woods, J.H.1    Winger, G.2    France, C.P.3
  • 36
    • 2342587417 scopus 로고    scopus 로고
    • Opioid peptide receptor studies. 17. Attenuation of chronic morphine effects after antisense oligodeoxynucleotide knock-down of RGS9 protein in cells expressing the cloned mu opioid receptor
    • Xu H., Wang X., Wang J., Rothman R.B. Opioid peptide receptor studies. 17. Attenuation of chronic morphine effects after antisense oligodeoxynucleotide knock-down of RGS9 protein in cells expressing the cloned mu opioid receptor. Synapse 2004, 52:209-217.
    • (2004) Synapse , vol.52 , pp. 209-217
    • Xu, H.1    Wang, X.2    Wang, J.3    Rothman, R.B.4
  • 37
    • 33846251929 scopus 로고    scopus 로고
    • A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence
    • Xu H., Partilla J.S., Wang X., Rutherford J.M., Tidgewell K., Prisinzano T.E., Bohn L.M., Rothman R.B. A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence. Synapse 2007, 61:166-175.
    • (2007) Synapse , vol.61 , pp. 166-175
    • Xu, H.1    Partilla, J.S.2    Wang, X.3    Rutherford, J.M.4    Tidgewell, K.5    Prisinzano, T.E.6    Bohn, L.M.7    Rothman, R.B.8
  • 38
    • 0017484168 scopus 로고
    • Inhibition by naloxone and dependence in mice treated acutely and chronically with morphine
    • Yano I., Takemori A.E. Inhibition by naloxone and dependence in mice treated acutely and chronically with morphine. Res. Commun. Chem. Pathol. Pharmacol. 1977, 16:721-734.
    • (1977) Res. Commun. Chem. Pathol. Pharmacol. , vol.16 , pp. 721-734
    • Yano, I.1    Takemori, A.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.