In vivo characterization of 6β-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 3, 2005, Pages 1150-1162

  Raehal, Kirsten M ^b   Lowery, John J ^a   Bhamidipati, Castigliano M ^a   Paolino, Ryan M ^a   Blair, Jennifer R ^a   Wang, Danxin ^b   Sadée, Wolfgang ^b   Bilsky, Edward J ^a  

^a UNIVERSITY OF NEW ENGLAND   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR ANTAGONIST; NALBUPHINE; NALOXONE; NALTREXOL; NALTREXONE; OPIATE; 6 BETA HYDROXYNALTREXONE; 6 BETA-HYDROXYNALTREXONE; 7 BENZYLIDENENALTREXONE; 7-BENZYLIDENENALTREXONE; BENZYLIDENE DERIVATIVE; DRUG DERIVATIVE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); NARCOTIC ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG OVERDOSE; DRUG POTENCY; DRUG STRUCTURE; LOCOMOTION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; WITHDRAWAL SYNDROME; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOTOR ACTIVITY;

ANIMALS; BENZYLIDENE COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MALE; MICE; MICE, INBRED ICR; MORPHINE; MOTOR ACTIVITY; NALOXONE; NALTREXONE; NARCOTIC ANTAGONISTS; OPIOID-RELATED DISORDERS;

EID: 19444361830     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.082966     Document Type: Article

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