Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by fasudil: Therapeutic implications for severe malaria

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Zang Edou, Estelle S ^a   Bisvigou, Ulrick ^a   Taoufiq, Zacharie ^b   Lékoulou, Faustin ^a   Lékana Douki, Jean Bernard ^a   Traoré, Yves ^c   Mazier, Dominique ^b,d,e   Touré Ndouo, Fousseyni S ^a  

^a CENTRE INTERNATIONAL DE RECHERCHES MÉDICALES DE FRANCEVILLE   (Gabon)

^b INSERM   (France)

^c UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

^d SORBONNE UNIVERSITÉ   (France)

^e ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FASUDIL; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ANTIMALARIAL AGENT; DRUG DERIVATIVE;

ADOLESCENT; ANTIMALARIAL ACTIVITY; APOPTOSIS; ARTICLE; CELL ADHESION; CELL CONTACT; CHILD; COCULTURE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; ENDOTHELIUM CELL; ERYTHROCYTE; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; SCHOOL CHILD; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; INFANT; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

PLASMODIUM FALCIPARUM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADOLESCENT; ANIMALS; ANTIMALARIALS; APOPTOSIS; CELL ADHESION; CHILD; CHILD, PRESCHOOL; ENDOTHELIUM, VASCULAR; HUMANS; INFANT; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM;

EID: 78049300061     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013221     Document Type: Article

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