CYP1A2 is more variable than previously thought: A genomic biography of the gene behind the human drug-metabolizing enzyme

Pharmacogenetics and Genomics

Volumn 20, Issue 11, 2010, Pages 647-664

  Browning, Sarah L ^a   Tarekegn, Ayele ^a,b   Bekele, Endashaw ^b   Bradman, Neil ^a   Thomas, Mark G ^a,c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ADDIS ABABA UNIVERSITY   (Ethiopia)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

CYP1A2; cytochrome P450 1A2; drug metabolism; Ethiopia; microsatellite; pharmacogenetics; purifying selection; SNPstr; time to most recent common ancestor

Indexed keywords

CYTOCHROME P450 1A2; MICROSATELLITE DNA;

ADULT; ARTICLE; DRUG METABOLISM; ETHIOPIA; ETHNICITY; GENE SEQUENCE; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 78049294655     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e32833e90eb     Document Type: Article

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