-
1
-
-
0038035670
-
Paresis of a bone morphogenetic protein antagonist response in a genetic disorder of heterotopic skeletogenesis
-
Ahn J., Serrano de la Peña L., Shore E.M., Kaplan F.S. Paresis of a bone morphogenetic protein antagonist response in a genetic disorder of heterotopic skeletogenesis. J. Bone Joint Surg. 2003, 85-A:667-674.
-
(2003)
J. Bone Joint Surg.
, pp. 667-674
-
-
Ahn, J.1
Serrano de la Peña, L.2
Shore, E.M.3
Kaplan, F.S.4
-
2
-
-
37249016863
-
Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva
-
Billings P.C., Fiori J.L., Bentwood J.L., O'Connell M.P., Jiao X., Nussbaum B., Caron R.J., Shore E.M., Kaplan F.S. Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva. J. Bone Miner. Res. 2008, 23:305-313.
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 305-313
-
-
Billings, P.C.1
Fiori, J.L.2
Bentwood, J.L.3
O'Connell, M.P.4
Jiao, X.5
Nussbaum, B.6
Caron, R.J.7
Shore, E.M.8
Kaplan, F.S.9
-
3
-
-
70649102232
-
ACVR1 knock-in mouse model for fibrodysplasia ossificans progressiva
-
Chakkalakal S.A., Zhang D., Raabe T., Richa J., Hankenson K., Kaplan F.S., Shore E.M. ACVR1 knock-in mouse model for fibrodysplasia ossificans progressiva. J. Bone Miner. Res. 2008, 23:s57.
-
(2008)
J. Bone Miner. Res.
, vol.23
-
-
Chakkalakal, S.A.1
Zhang, D.2
Raabe, T.3
Richa, J.4
Hankenson, K.5
Kaplan, F.S.6
Shore, E.M.7
-
4
-
-
33646865518
-
Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP)
-
Fiori J.L., Billings P.C., Serrano de la Peña L., Kaplan F.S., Shore E.M. Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP). J. Bone Miner. Res. 2006, 21:902-909.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 902-909
-
-
Fiori, J.L.1
Billings, P.C.2
Serrano de la Peña, L.3
Kaplan, F.S.4
Shore, E.M.5
-
5
-
-
33646560934
-
Generation of a mouse with conditionally activating signaling through the BMP receptor ALK2
-
Fukuda T., Scott G., Komatsu Y., Araya R., Kawano M., Ray M.K., Yamada M., Mishina Y. Generation of a mouse with conditionally activating signaling through the BMP receptor ALK2. Genesis 2006, 44:159-167.
-
(2006)
Genesis
, vol.44
, pp. 159-167
-
-
Fukuda, T.1
Scott, G.2
Komatsu, Y.3
Araya, R.4
Kawano, M.5
Ray, M.K.6
Yamada, M.7
Mishina, Y.8
-
6
-
-
65449139561
-
Constitutively activated ALK2 and increased SMAD 1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva
-
Fukuda T., Kohda M., Kanomata K., Nojima J., Nakamura A., Kamizono J., Noguchi Y., Iwakiri K., Kondo T., Kurose J., Endo K.I., Awakura T., et al. Constitutively activated ALK2 and increased SMAD 1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva. J. Biol. Chem. 2009, 284:7149-7156.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7149-7156
-
-
Fukuda, T.1
Kohda, M.2
Kanomata, K.3
Nojima, J.4
Nakamura, A.5
Kamizono, J.6
Noguchi, Y.7
Iwakiri, K.8
Kondo, T.9
Kurose, J.10
Endo, K.I.11
Awakura, T.12
-
7
-
-
10744229194
-
In vivo somatic cell gene transfer of an engineered noggin mutein prevents BMP4-induced heterotopic ossification
-
Glaser D.L., Economides A.N., Wang L., Liu X., Kimble R.D., Fandl J.P., Wilson J.M., Stahl N., Kaplan F.S., Shore E.M. In vivo somatic cell gene transfer of an engineered noggin mutein prevents BMP4-induced heterotopic ossification. J. Bone Joint Surg. 2003, 85-A:2332-2342.
-
(2003)
J. Bone Joint Surg.
, pp. 2332-2342
-
-
Glaser, D.L.1
Economides, A.N.2
Wang, L.3
Liu, X.4
Kimble, R.D.5
Fandl, J.P.6
Wilson, J.M.7
Stahl, N.8
Kaplan, F.S.9
Shore, E.M.10
-
9
-
-
45449087921
-
QBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
-
Hellemans J., Mortier G., DePaepe A., Speleman F., Vandesompele J. QBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol. 2007, 8(2):R19.
-
(2007)
Genome Biol.
, vol.8
, Issue.2
-
-
Hellemans, J.1
Mortier, G.2
DePaepe, A.3
Speleman, F.4
Vandesompele, J.5
-
10
-
-
4644264945
-
Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype
-
Kan L., Hu M., Gomes W.A., Kessler J.A. Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype. Am. J. Pathol. 2004, 165:1107-1115.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 1107-1115
-
-
Kan, L.1
Hu, M.2
Gomes, W.A.3
Kessler, J.A.4
-
11
-
-
59849119987
-
Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification
-
Kan L., McGuire T.L., Berger D.M., Awatramani R.B., Dymeki S.M., Kessler J.A. Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification. Stem Cells 2009, 27:150-156.
-
(2009)
Stem Cells
, vol.27
, pp. 150-156
-
-
Kan, L.1
McGuire, T.L.2
Berger, D.M.3
Awatramani, R.B.4
Dymeki, S.M.5
Kessler, J.A.6
-
12
-
-
25844487690
-
The phenotype of fibrodysplasia ossificans progressiva
-
Kaplan F.S., Glaser D.L., Shore E.M., Deirmengian G.K., Gupta R., Delai P., Morhart P., Smith R., Le Merrer M., Rogers J.G., Connor J.M., Kitterman J.A. The phenotype of fibrodysplasia ossificans progressiva. Clin. Rev. Bone Miner. Metab. 2005, 3:183-188.
-
(2005)
Clin. Rev. Bone Miner. Metab.
, vol.3
, pp. 183-188
-
-
Kaplan, F.S.1
Glaser, D.L.2
Shore, E.M.3
Deirmengian, G.K.4
Gupta, R.5
Delai, P.6
Morhart, P.7
Smith, R.8
Le Merrer, M.9
Rogers, J.G.10
Connor, J.M.11
Kitterman, J.A.12
-
13
-
-
33846839273
-
Hematopoietic stem-cell contribution to ectopic skeletogenesis
-
Kaplan F.S., Glaser D.L., Shore E.M., Pignolo R.J., Xu M., Zhang Y., Senitzer D., Forman S.J., Emerson S.G. Hematopoietic stem-cell contribution to ectopic skeletogenesis. J. Bone Joint Surg. Am. 2007, 89:347-357.
-
(2007)
J. Bone Joint Surg. Am.
, vol.89
, pp. 347-357
-
-
Kaplan, F.S.1
Glaser, D.L.2
Shore, E.M.3
Pignolo, R.J.4
Xu, M.5
Zhang, Y.6
Senitzer, D.7
Forman, S.J.8
Emerson, S.G.9
-
14
-
-
37249082497
-
Morphogen receptor genes and metamorphogenes: Skeleton keys to metamorphosis
-
Kaplan F.S., Groppe J., Pignolo R.J., Shore E.M. Morphogen receptor genes and metamorphogenes: Skeleton keys to metamorphosis. Ann. NY Acad. Sci. 2007, 1116:113-133.
-
(2007)
Ann. NY Acad. Sci.
, vol.1116
, pp. 113-133
-
-
Kaplan, F.S.1
Groppe, J.2
Pignolo, R.J.3
Shore, E.M.4
-
15
-
-
40149099148
-
Fibrodysplasia ossificans progressiva
-
Kaplan F.S., LeMerrer M., Glaser D.L., Pignolo R.J., Goldsby R.E., Kitterman J.A., Groppe J., Shore E.M. Fibrodysplasia ossificans progressiva. Best Pract. Res. Clin. Rheumatol. 2008, 22:191-205.
-
(2008)
Best Pract. Res. Clin. Rheumatol.
, vol.22
, pp. 191-205
-
-
Kaplan, F.S.1
LeMerrer, M.2
Glaser, D.L.3
Pignolo, R.J.4
Goldsby, R.E.5
Kitterman, J.A.6
Groppe, J.7
Shore, E.M.8
-
16
-
-
44449166223
-
Early diagnosis of fibrodysplasia ossificans progressiva
-
Kaplan F.S., Xu M., Glaser D.L., Collins F., Connor M., Kitterman J., Sillence D., Zackai E., Ravitsky V., Zasloff M., Ganguly A., Shore E.M. Early diagnosis of fibrodysplasia ossificans progressiva. Pediatrics 2008, 121:e1295-e1300.
-
(2008)
Pediatrics
, vol.121
-
-
Kaplan, F.S.1
Xu, M.2
Glaser, D.L.3
Collins, F.4
Connor, M.5
Kitterman, J.6
Sillence, D.7
Zackai, E.8
Ravitsky, V.9
Zasloff, M.10
Ganguly, A.11
Shore, E.M.12
-
17
-
-
70649090107
-
The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling
-
Kaplan F.S., Pignolo R.J., Shore E.M. The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling. Cytokine Growth Factor Rev. 2009, 20:399-407.
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 399-407
-
-
Kaplan, F.S.1
Pignolo, R.J.2
Shore, E.M.3
-
18
-
-
61649084689
-
Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1
-
Kaplan F.S., Xu M., Seemann P., Connor J.M., Glaser D.L., Carroll L., Delai P., Xu M., Seemann P., Connor J.M., Glaser D.L., Carroll L., et al. Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1. Hum. Mutat. 2009, 30(3):379-390.
-
(2009)
Hum. Mutat.
, vol.30
, Issue.3
, pp. 379-390
-
-
Kaplan, F.S.1
Xu, M.2
Seemann, P.3
Connor, J.M.4
Glaser, D.L.5
Carroll, L.6
Delai, P.7
Xu, M.8
Seemann, P.9
Connor, J.M.10
Glaser, D.L.11
Carroll, L.12
-
19
-
-
0036732838
-
Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis
-
Katagiri T., Imada M., Yanai T., Suda T., Takahashi N., Kamijo R. Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis. Genes Cells 2002, 7:949-960.
-
(2002)
Genes Cells
, vol.7
, pp. 949-960
-
-
Katagiri, T.1
Imada, M.2
Yanai, T.3
Suda, T.4
Takahashi, N.5
Kamijo, R.6
-
20
-
-
25444441297
-
Evaluation of the stability of six host genes as internal control in real-time RT-PCR assays in chicken embryo cell cultures infected with infectious bursal disease virus
-
Li Y.P., Bang D.D., Handberg K.J., Jorgensen P.H., Zhang M.F. Evaluation of the stability of six host genes as internal control in real-time RT-PCR assays in chicken embryo cell cultures infected with infectious bursal disease virus. Vet. Micrbiol. 2005, 110:155-165.
-
(2005)
Vet. Micrbiol.
, vol.110
, pp. 155-165
-
-
Li, Y.P.1
Bang, D.D.2
Handberg, K.J.3
Jorgensen, P.H.4
Zhang, M.F.5
-
21
-
-
33750740452
-
Extracellular modulation of BMP activity in patterning the dorsoventral axis
-
Little S.C., Mullins M.C. Extracellular modulation of BMP activity in patterning the dorsoventral axis. Birth Defects Res. C. Embryo Today 2006, 78:224-242.
-
(2006)
Birth Defects Res. C. Embryo Today
, vol.78
, pp. 224-242
-
-
Little, S.C.1
Mullins, M.C.2
-
22
-
-
62549145351
-
Identification of progenitor cells that contribute to heterotopic skeletogenesis
-
Lounev V., Ramachandran R., Wosczyna M.N., Yamamoto M., Maidment A.D.A., Shore E.M., Glaser D.L., Goldhamer D.J., Kaplan F.S. Identification of progenitor cells that contribute to heterotopic skeletogenesis. J. Bone Joint Surg. Am. 2009, 91:652-663.
-
(2009)
J. Bone Joint Surg. Am.
, vol.91
, pp. 652-663
-
-
Lounev, V.1
Ramachandran, R.2
Wosczyna, M.N.3
Yamamoto, M.4
Maidment, A.D.A.5
Shore, E.M.6
Glaser, D.L.7
Goldhamer, D.J.8
Kaplan, F.S.9
-
23
-
-
0037687418
-
SHED: Stem cells from human exfoliated deciduous teeth
-
Miura M., Gronthos S., Zhao M., Lu B., Fisher L.W., Robey P.G., Shi S. SHED: Stem cells from human exfoliated deciduous teeth. Proc. Natl. Am. Sci. USA 2003, 100:5807-5812.
-
(2003)
Proc. Natl. Am. Sci. USA
, vol.100
, pp. 5807-5812
-
-
Miura, M.1
Gronthos, S.2
Zhao, M.3
Lu, B.4
Fisher, L.W.5
Robey, P.G.6
Shi, S.7
-
24
-
-
20844450082
-
Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA
-
Serrano de la Peña L., Billings P.C., Fiori J.L., Ahn J., Shore E.M., Kaplan F.S. Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA. J. Bone Miner. Res. 2005, 20:1168-1176.
-
(2005)
J. Bone Miner. Res.
, vol.20
, pp. 1168-1176
-
-
Serrano de la Peña, L.1
Billings, P.C.2
Fiori, J.L.3
Ahn, J.4
Shore, E.M.5
Kaplan, F.S.6
-
25
-
-
0029746491
-
Over-expression of an osteogenic morphogen in fibrodysplasia ossificans progressiva
-
Shafritz A.B., Shore E.M., Gannon F.H., Zasloff M.A., Taub R., Muenke M., Kaplan F.S. Over-expression of an osteogenic morphogen in fibrodysplasia ossificans progressiva. N. Engl. J. Med. 1996, 335:555-561.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 555-561
-
-
Shafritz, A.B.1
Shore, E.M.2
Gannon, F.H.3
Zasloff, M.A.4
Taub, R.5
Muenke, M.6
Kaplan, F.S.7
-
26
-
-
70449366408
-
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
-
Shen Q., Little S.C., Xu M., Haupt J., Ast C., Katagiri T., Mundlos S., Seemann P., Kaplan F.S., Mullins M.C., Shore E.M. The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J. Clin. Invest. 2009, 119(11):3462-3472.
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.11
, pp. 3462-3472
-
-
Shen, Q.1
Little, S.C.2
Xu, M.3
Haupt, J.4
Ast, C.5
Katagiri, T.6
Mundlos, S.7
Seemann, P.8
Kaplan, F.S.9
Mullins, M.C.10
Shore, E.M.11
-
27
-
-
25844453495
-
The genetics of fibrodysplasia ossificans progressiva
-
Shore E.M., Feldman G.J., Xu M., Kaplan F.S. The genetics of fibrodysplasia ossificans progressiva. Clin. Rev. Bone Miner. Metab. 2005, 3:201-204.
-
(2005)
Clin. Rev. Bone Miner. Metab.
, vol.3
, pp. 201-204
-
-
Shore, E.M.1
Feldman, G.J.2
Xu, M.3
Kaplan, F.S.4
-
28
-
-
33646348736
-
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
-
Shore E.M., Xu M., Feldman G.J., Fenstermacher D.A., Cho T.-J., Choi I.H., Connor J.M., Delai P., Glaser D.L., Le Merrer M., Morhart R., Rogers J.G., et al. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat. Genet. 2006, 38:525-527.
-
(2006)
Nat. Genet.
, vol.38
, pp. 525-527
-
-
Shore, E.M.1
Xu, M.2
Feldman, G.J.3
Fenstermacher, D.A.4
Cho, T.-J.5
Choi, I.H.6
Connor, J.M.7
Delai, P.8
Glaser, D.L.9
Le Merrer, M.10
Morhart, R.11
Rogers, J.G.12
-
29
-
-
70649083092
-
Recent advances in BMP receptor signaling
-
Sieber C., Kopf J., Hiepen C., Knaus P. Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev. 2009, 20:353-355.
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 353-355
-
-
Sieber, C.1
Kopf, J.2
Hiepen, C.3
Knaus, P.4
-
30
-
-
70649097373
-
Functional analysis of saxophone, the drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1A and ACVR1/ALK2
-
Twombly V., Bangi E., Le V., Malnic B., Singer M.A., Wharton K.A. Functional analysis of saxophone, the drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1A and ACVR1/ALK2. Genetics 2009, 83:563-579.
-
(2009)
Genetics
, vol.83
, pp. 563-579
-
-
Twombly, V.1
Bangi, E.2
Le, V.3
Malnic, B.4
Singer, M.A.5
Wharton, K.A.6
-
31
-
-
34250019537
-
Bone formation by autoinduction
-
Urist M. Bone formation by autoinduction. Science 1965, 150(698):893-899.
-
(1965)
Science
, vol.150
, Issue.698
, pp. 893-899
-
-
Urist, M.1
-
32
-
-
77953497987
-
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation
-
van Dinther M., Visser N., de Gorter D.J.J., Doorn J., Goumans M.-J., de Boer J., ten Dijke P. ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation. J. Bone Miner. Res. 2009, 25:1208-1215.
-
(2009)
J. Bone Miner. Res.
, vol.25
, pp. 1208-1215
-
-
van Dinther, M.1
Visser, N.2
de Gorter, D.J.J.3
Doorn, J.4
Goumans, M.-J.5
de Boer, J.6
ten Dijke, P.7
-
33
-
-
0024256133
-
Novel regulators of bone formation: Molecular clones and activities
-
Wozney J.M., Rosen V., Celeste A.J., Mitsock L.M., Whitters M.J., Kriz R.W., Hewick R.M., Wang E.A. Novel regulators of bone formation: Molecular clones and activities. Science 1998, 242(4885):1528-1534.
-
(1998)
Science
, vol.242
, Issue.4885
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
Hewick, R.M.7
Wang, E.A.8
-
34
-
-
37249010753
-
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
-
Yu P.B., Hong C.C., Sachidanandan C., Babitt J.L., Deng D.Y., Hoyng S.A., Lin H.Y., Bloch K.D., Peterson R.T. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat. Chem. Biol. 2008, 4:33-41.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 33-41
-
-
Yu, P.B.1
Hong, C.C.2
Sachidanandan, C.3
Babitt, J.L.4
Deng, D.Y.5
Hoyng, S.A.6
Lin, H.Y.7
Bloch, K.D.8
Peterson, R.T.9
-
35
-
-
57349171954
-
BMP type I receptor inhibition reduces heterotopic ossification
-
Yu P.B., Deng D.Y., Lai C.S., Hong C.C., Cuny G.D., Bouxsein M.L., Hong D.W., McManus P.M., Katagiri T., Sachidanandan C., Nobuhiro K., Fukuda T., et al. BMP type I receptor inhibition reduces heterotopic ossification. Nat. Med. 2008, 14:1363-1369.
-
(2008)
Nat. Med.
, vol.14
, pp. 1363-1369
-
-
Yu, P.B.1
Deng, D.Y.2
Lai, C.S.3
Hong, C.C.4
Cuny, G.D.5
Bouxsein, M.L.6
Hong, D.W.7
McManus, P.M.8
Katagiri, T.9
Sachidanandan, C.10
Nobuhiro, K.11
Fukuda, T.12
-
36
-
-
0042978771
-
ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development
-
Zhang D., Schwarz E.M., Rosier R.N., Zuscik M.J., Puzas J.E., O'Keefe R.J. ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. J. Bone Miner. Res. 2003, 18:1593-1604.
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 1593-1604
-
-
Zhang, D.1
Schwarz, E.M.2
Rosier, R.N.3
Zuscik, M.J.4
Puzas, J.E.5
O'Keefe, R.J.6
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