-
1
-
-
59149097625
-
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
-
Meyre D, Delplanque J, Chèvre JC, Lecoeur C, Lobbens S, Gallina S, Durand E, Vatin V, Degraeve F, Proença C, Gaget S, Körner A, Kovacs P, Kiess W, Tichet J, Marre M, Hartikainen AL, Horber F, Potoczna N, Hercberg S, Levy-Marchal C, Pattou F, Heude B, Tauber M, McCarthy MI, Blakemore AI, Montpetit A, Polychronakos C, Weill J, Coin LJ, Asher J, Elliott P, Järvelin MR, Visvikis-Siest S, Balkau B, Sladek R, Balding D, Walley A, Dina C, Froguel P. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet 2009;41:157-159
-
(2009)
Nat Genet
, vol.41
, pp. 157-159
-
-
Meyre, D.1
Delplanque, J.2
Chèvre, J.C.3
Lecoeur, C.4
Lobbens, S.5
Gallina, S.6
Durand, E.7
Vatin, V.8
Degraeve, F.9
Proença, C.10
Gaget, S.11
Körner, A.12
Kovacs, P.13
Kiess, W.14
Tichet, J.15
Marre, M.16
Hartikainen, A.L.17
Horber, F.18
Potoczna, N.19
Hercberg, S.20
Levy-Marchal, C.21
Pattou, F.22
Heude, B.23
Tauber, M.24
McCarthy, M.I.25
Blakemore, A.I.26
Montpetit, A.27
Polychronakos, C.28
Weill, J.29
Coin, L.J.30
Asher, J.31
Elliott, P.32
Järvelin, M.R.33
Visvikis-Siest, S.34
Balkau, B.35
Sladek, R.36
Balding, D.37
Walley, A.38
Dina, C.39
Froguel, P.40
more..
-
2
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316:889-894
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.36
Doney, A.S.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
3
-
-
44849086097
-
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity
-
Liu YJ, Liu XG, Wang L, Dina C, Yan H, Liu JF, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Meyre D, Delplanque J, Pei YF, Zhang L, Recker RR, Froguel P, Deng HW. Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet 2008;17:1803-1813
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1803-1813
-
-
Liu, Y.J.1
Liu, X.G.2
Wang, L.3
Dina, C.4
Yan, H.5
Liu, J.F.6
Levy, S.7
Papasian, C.J.8
Drees, B.M.9
Hamilton, J.J.10
Meyre, D.11
Delplanque, J.12
Pei, Y.F.13
Zhang, L.14
Recker, R.R.15
Froguel, P.16
Deng, H.W.17
-
4
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, KORA, Nurses' Health Study, Diabetes Genetics Initiative, SardiNIA Study, Wellcome Trust Case Control Consortium, FUSION
-
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Farooqi S, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM, KORA, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L, Nurses' Health Study, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK, Diabetes Genetics Initiative, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M, SardiNIA Study, Vogel CI, Wallace C, Waterworth DM, Weedon MN, Wellcome Trust Case Control Consortium, Willer CJ, FUSION, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008;40:768-775
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
Wheeler, E.4
Zhao, J.H.5
Prokopenko, I.6
Inouye, M.7
Freathy, R.M.8
Attwood, A.P.9
Beckmann, J.S.10
Berndt, S.I.11
Jacobs, K.B.12
Chanock, S.J.13
Hayes, R.B.14
Bergmann, S.15
Bennett, A.J.16
Bingham, S.A.17
Bochud, M.18
Brown, M.19
Cauchi, S.20
Connell, J.M.21
Cooper, C.22
Smith, G.D.23
Day, I.24
Dina, C.25
De, S.26
Dermitzakis, E.T.27
Doney, A.S.28
Elliott, K.S.29
Elliott, P.30
Evans, D.M.31
Farooqi, S.32
Froguel, P.33
Ghori, J.34
Groves, C.J.35
Gwilliam, R.36
Hadley, D.37
Hall, A.S.38
Hattersley, A.T.39
Hebebrand, J.40
Heid, I.M.41
Lamina, C.42
Gieger, C.43
Illig, T.44
Meitinger, T.45
Wichmann, H.E.46
Herrera, B.47
Hinney, A.48
Hunt, S.E.49
Jarvelin, M.R.50
Johnson, T.51
Jolley, J.D.52
Karpe, F.53
Keniry, A.54
Khaw, K.T.55
Luben, R.N.56
Mangino, M.57
Marchini, J.58
McArdle, W.L.59
McGinnis, R.60
Meyre, D.61
Munroe, P.B.62
Morris, A.D.63
Ness, A.R.64
Neville, M.J.65
Nica, A.C.66
Ong, K.K.67
O'Rahilly, S.68
Owen, K.R.69
Palmer, C.N.70
Papadakis, K.71
Potter, S.72
Pouta, A.73
Qi, L.74
Randall, J.C.75
Rayner, N.W.76
Ring, S.M.77
Sandhu, M.S.78
Scherag, A.79
Sims, M.A.80
Song, K.81
Soranzo, N.82
Speliotes, E.K.83
Syddall, H.E.84
Teichmann, S.A.85
Timpson, N.J.86
Tobias, J.H.87
Uda, M.88
Vogel, C.I.89
Wallace, C.90
Waterworth, D.M.91
Weedon, M.N.92
Willer, C.J.93
Wraight94
Yuan, X.95
Zeggini, E.96
Hirschhorn, J.N.97
Strachan, D.P.98
Ouwehand, W.H.99
more..
-
5
-
-
67349188883
-
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
-
Cho YS, Go MJ, Kim YJ, Heo JY, Oh JH, Ban HJ, Yoon D, Lee MH, Kim DJ, Park M, Cha SH, Kim JW, Han BG, Min H, Ahn Y, Park MS, Han HR, Jang HY, Cho EY, Lee JE, Cho NH, Shin C, Park T, Park JW, Lee JK, Cardon L, Clarke G, McCarthy MI, Lee JY, Lee JK, Oh B, Kim HL. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet 2009;41:527-534
-
(2009)
Nat Genet
, vol.41
, pp. 527-534
-
-
Cho, Y.S.1
Go, M.J.2
Kim, Y.J.3
Heo, J.Y.4
Oh, J.H.5
Ban, H.J.6
Yoon, D.7
Lee, M.H.8
Kim, D.J.9
Park, M.10
Cha, S.H.11
Kim, J.W.12
Han, B.G.13
Min, H.14
Ahn, Y.15
Park, M.S.16
Han, H.R.17
Jang, H.Y.18
Cho, E.Y.19
Lee, J.E.20
Cho, N.H.21
Shin, C.22
Park, T.23
Park, J.W.24
Lee, J.K.25
Cardon, L.26
Clarke, G.27
McCarthy, M.I.28
Lee, J.Y.29
Lee, J.K.30
Oh, B.31
Kim, H.L.32
more..
-
6
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Wellcome Trust Case Control Consortium, Genetic Investigation of ANthropometric Traits Consortium
-
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN, Genetic Investigation of ANthropometric Traits Consortium. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
Li, S.4
Lindgren, C.M.5
Heid, I.M.6
Berndt, S.I.7
Elliott, A.L.8
Jackson, A.U.9
Lamina, C.10
Lettre, G.11
Lim, N.12
Lyon, H.N.13
McCarroll, S.A.14
Papadakis, K.15
Qi, L.16
Randall, J.C.17
Roccasecca, R.M.18
Sanna, S.19
Scheet, P.20
Weedon, M.N.21
Wheeler, E.22
Zhao, J.H.23
Jacobs, L.C.24
Prokopenko, I.25
Soranzo, N.26
Tanaka, T.27
Timpson, N.J.28
Almgren, P.29
Bennett, A.30
Bergman, R.N.31
Bingham, S.A.32
Bonnycastle, L.L.33
Brown, M.34
Burtt, N.P.35
Chines, P.36
Coin, L.37
Collins, F.S.38
Connell, J.M.39
Cooper, C.40
Smith, G.D.41
Dennison, E.M.42
Deodhar, P.43
Elliott, P.44
Erdos, M.R.45
Estrada, K.46
Evans, D.M.47
Gianniny, L.48
Gieger, C.49
Gillson, C.J.50
Guiducci, C.51
Hackett, R.52
Hadley, D.53
Hall, A.S.54
Havulinna, A.S.55
Hebebrand, J.56
Hofman, A.57
Isomaa, B.58
Jacobs, K.B.59
Johnson, T.60
Jousilahti, P.61
Jovanovic, Z.62
Khaw, K.T.63
Kraft, P.64
Kuokkanen, M.65
Kuusisto, J.66
Laitinen, J.67
Lakatta, E.G.68
Luan, J.69
Luben, R.N.70
Mangino, M.71
McArdle, W.L.72
Meitinger, T.73
Mulas, A.74
Munroe, P.B.75
Narisu, N.76
Ness, A.R.77
Northstone, K.78
O'Rahilly, S.79
Purmann, C.80
Rees, M.G.81
Ridderstråle, M.82
Ring, S.M.83
Rivadeneira, F.84
Ruokonen, A.85
Sandhu, M.S.86
Saramies, J.87
Scott, L.J.88
Scuteri, A.89
Silander, K.90
Sims, M.A.91
Song, K.92
Stephens, J.93
Stevens, S.94
Stringham, H.M.95
Tung, Y.C.96
Valle, T.T.97
Van Duijn, C.M.98
Vimaleswaran, K.S.99
more..
-
7
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009;41:18-24
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
Steinthorsdottir, V.4
Sulem, P.5
Helgadottir, A.6
Styrkarsdottir, U.7
Gretarsdottir, S.8
Thorlacius, S.9
Jonsdottir, I.10
Jonsdottir, T.11
Olafsdottir, E.J.12
Olafsdottir, G.H.13
Jonsson, T.14
Jonsson, F.15
Borch-Johnsen, K.16
Hansen, T.17
Andersen, G.18
Jorgensen, T.19
Lauritzen, T.20
Aben, K.K.21
Verbeek, A.L.22
Roeleveld, N.23
Kampman, E.24
Yanek, L.R.25
Becker, L.C.26
Tryggvadottir, L.27
Rafnar, T.28
Becker, D.M.29
Gulcher, J.30
Kiemeney, L.A.31
Pedersen, O.32
Kong, A.33
Thorsteinsdottir, U.34
Stefansson, K.35
more..
-
8
-
-
4644240052
-
Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians
-
Ma L, Tataranni PA, Bogardus C, Baier LJ. Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians. Diabetes 2004;53:2696-12699
-
(2004)
Diabetes
, vol.53
, pp. 2696-12699
-
-
Ma, L.1
Tataranni, P.A.2
Bogardus, C.3
Baier, L.J.4
-
9
-
-
58149339706
-
Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant
-
Krakoff J, Ma L, Kobes S, Knowler WC, Hanson RL, Bogardus C, Baier LJ. Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant. Diabetes 2008;57:3267-3272
-
(2008)
Diabetes
, vol.57
, pp. 3267-3272
-
-
Krakoff, J.1
Ma, L.2
Kobes, S.3
Knowler, W.C.4
Hanson, R.L.5
Bogardus, C.6
Baier, L.J.7
-
10
-
-
67650224470
-
Common variation in SIM1 is reproducibly associated with BMI in Pima Indians
-
Traurig M, Mack J, Hanson RL, Ghoussaini M, Meyre D, Knowler WC, Kobes S, Froguel P, Bogardus C, Baier LJ. Common variation in SIM1 is reproducibly associated with BMI in Pima Indians. Diabetes 2009;58:1682-1689
-
(2009)
Diabetes
, vol.58
, pp. 1682-1689
-
-
Traurig, M.1
Mack, J.2
Hanson, R.L.3
Ghoussaini, M.4
Meyre, D.5
Knowler, W.C.6
Kobes, S.7
Froguel, P.8
Bogardus, C.9
Baier, L.J.10
-
11
-
-
0023683122
-
6q1 monosomy: A distinctive syndrome
-
Turleau C, Demay G, Cabanis MO, Lenoir G, de Grouchy J. 6q1 monosomy: a distinctive syndrome. Clin Genet 1988;34:38-42
-
(1988)
Clin Genet
, vol.34
, pp. 38-42
-
-
Turleau, C.1
Demay, G.2
Cabanis, M.O.3
Lenoir, G.4
De Grouchy, J.5
-
13
-
-
0034016043
-
Profound obesity associated with a balanced translocation that disrupts the SIM1 gene
-
Holder JL Jr, Butte NF, Zinn AR. Profound obesity associated with a balanced translocation that disrupts the SIM1 gene. Hum Mol Genet 2000;9:101-108
-
(2000)
Hum Mol Genet
, vol.9
, pp. 101-108
-
-
Holder Jr., J.L.1
Butte, N.F.2
Zinn, A.R.3
-
15
-
-
18444412266
-
Deletion of the SIM1 gene (6q16.2) in a patient with a Prader-Willi-like phenotype
-
Faivre L, Cormier-Daire V, Lapierre JM, Colleaux L, Jacquemont S, Geneviéve D, Saunier P, Munnich A, Turleau C, Romana S, Prieur M, De Blois MC, Vekemans M. Deletion of the SIM1 gene (6q16.2) in a patient with a Prader-Willi-like phenotype. J Med Genet 2002;39:594-596
-
(2002)
J Med Genet
, vol.39
, pp. 594-596
-
-
Faivre, L.1
Cormier-Daire, V.2
Lapierre, J.M.3
Colleaux, L.4
Jacquemont, S.5
Geneviéve, D.6
Saunier, P.7
Munnich, A.8
Turleau, C.9
Romana, S.10
Prieur, M.11
De Blois, M.C.12
Vekemans, M.13
-
16
-
-
33745612078
-
A new case of interstitial 6q16.2 deletion in a patient with Prader-Willi-like phenotype and investigation of SIM1 gene deletion in 87 patients with syndromic obesity
-
Varela MC, Simões-Sato AY, Kim CA, Bertola DR, De Castro CI, Koiffmann CP. A new case of interstitial 6q16.2 deletion in a patient with Prader-Willi-like phenotype and investigation of SIM1 gene deletion in 87 patients with syndromic obesity. Eur J Med Genet 2006;49:298-305
-
(2006)
Eur J Med Genet
, vol.49
, pp. 298-305
-
-
Varela, M.C.1
Simões-Sato, A.Y.2
Kim, C.A.3
Bertola, D.R.4
De Castro, C.I.5
Koiffmann, C.P.6
-
17
-
-
56749159050
-
Detailed phenotype-genotype study in five patients with chromosome 6q16 deletion: Narrowing the critical region for Prader-Willi-like phenotype
-
Bonaglia MC, Ciccone R, Gimelli G, Gimelli S, Marelli S, Verheij J, Giorda R, Grasso R, Borgatti R, Pagone F, Rodrìguez L, Martinez-Frias ML, van Ravenswaaij C, Zuffardi O. Detailed phenotype-genotype study in five patients with chromosome 6q16 deletion: narrowing the critical region for Prader-Willi-like phenotype. Eur J Hum Genet 2008;16:1443-1449
-
(2008)
Eur J Hum Genet
, vol.16
, pp. 1443-1449
-
-
Bonaglia, M.C.1
Ciccone, R.2
Gimelli, G.3
Gimelli, S.4
Marelli, S.5
Verheij, J.6
Giorda, R.7
Grasso, R.8
Borgatti, R.9
Pagone, F.10
Rodrìguez, L.11
Martinez-Frias, M.L.12
Van Ravenswaaij, C.13
Zuffardi, O.14
-
18
-
-
56049124612
-
A 5-Mb microdeletion at 6q16.1-q16.3 with SIM gene deletion and obesity
-
Wang JC, Turner L, Lomax B, Eydoux P. A 5-Mb microdeletion at 6q16.1-q16.3 with SIM gene deletion and obesity. Am J Med Genet A 2008;146A:2975-2978
-
(2008)
Am J Med Genet A
, vol.146 A
, pp. 2975-2978
-
-
Wang, J.C.1
Turner, L.2
Lomax, B.3
Eydoux, P.4
-
19
-
-
76249113511
-
Loss-of-function mutations in SIM1 cause a specific form of Prader-Willi-like syndrome
-
Stutzmann F, Ghoussaini M, Couturier C, Marchand M, Vatin V, Corset L, Lecoeur C, Balkau B, Horber F, Driscoll DJ, Goldstone AP, Weill J, Michaud JL, Meyre D, Froguel P: Loss-of-function mutations in SIM1 cause a specific form of Prader-Willi-like syndrome. Diabetologia 2009;52:S104
-
(2009)
Diabetologia
, vol.52
-
-
Stutzmann, F.1
Ghoussaini, M.2
Couturier, C.3
Marchand, M.4
Vatin, V.5
Corset, L.6
Lecoeur, C.7
Balkau, B.8
Horber, F.9
Driscoll, D.J.10
Goldstone, A.P.11
Weill, J.12
Michaud, J.L.13
Meyre, D.14
Froguel, P.15
-
20
-
-
70849124572
-
Fox-1 family of RNA-binding proteins
-
Kuroyanagi H. Fox-1 family of RNA-binding proteins. Cell Mol Life Sci 2009;66:3895-3907
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3895-3907
-
-
Kuroyanagi, H.1
-
21
-
-
0034701797
-
A novel protein with RNA-binding motifs interacts with ataxin-2
-
Shibata H, Huynh DP, Pulst SM. A novel protein with RNA-binding motifs interacts with ataxin-2. Hum Mol Genet 2000;9:1303-1313
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1303-1313
-
-
Shibata, H.1
Huynh, D.P.2
Pulst, S.M.3
-
23
-
-
41149108443
-
Spinocerebellar ataxia type 2 (SCA2) in an Egyptian family presenting with polyphagia and marked CAG expansion in infancy
-
Abdel-Aleem A, Zaki MS. Spinocerebellar ataxia type 2 (SCA2) in an Egyptian family presenting with polyphagia and marked CAG expansion in infancy. J Neurol 2008;255:413-419
-
(2008)
J Neurol
, vol.255
, pp. 413-419
-
-
Abdel-Aleem, A.1
Zaki, M.S.2
-
24
-
-
28144444458
-
Generation and characterization of Sca2 (ataxin-2) knockout mice
-
Kiehl TR, Nechiporuk A, Figueroa KP, Keating MT, Huynh DP, Pulst SM. Generation and characterization of Sca2 (ataxin-2) knockout mice. Biochem Biophys Res Commun 2006;339:17-24
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 17-24
-
-
Kiehl, T.R.1
Nechiporuk, A.2
Figueroa, K.P.3
Keating, M.T.4
Huynh, D.P.5
Pulst, S.M.6
-
25
-
-
43049114214
-
Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice
-
DOI 10.1093/hmg/ddn035
-
Lastres-Becker I, Brodesser S, Lütjohann D, Azizov M, Buchmann J, Hintermann E, Sandhoff K, Schürmann A, Nowock J, Auburger G. Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice. Hum Mol Genet 2008;17:1465-1481 (Pubitemid 351627343)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.10
, pp. 1465-1481
-
-
Lastres-Becker, I.1
Brodesser, S.2
Lutjohann, D.3
Azizov, M.4
Buchmann, J.5
Hintermann, E.6
Sandhoff, K.7
Schurmann, A.8
Nowock, J.9
Auburger, G.10
-
26
-
-
16944362008
-
Genomewide search for genes influencing percent body fat in Pima Indians: Suggestive linkage at chromosome 11q21-q22
-
Pima Diabetes Gene Group
-
Norman RA, Thompson DB, Foroud T, Garvey WT, Bennett PH, Bogardus C, Ravussin E. Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group. Am J Hum Genet 1997;60:166-173
-
(1997)
Am J Hum Genet
, vol.60
, pp. 166-173
-
-
Norman, R.A.1
Thompson, D.B.2
Foroud, T.3
Garvey, W.T.4
Bennett, P.H.5
Bogardus, C.6
Ravussin, E.7
-
27
-
-
36849029819
-
A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array
-
DOI 10.2337/db07-0462
-
Hanson RL, Bogardus C, Duggan D, Kobes S, Knowlton M, Infante AM, Marovich L, Benitez D, Baier LJ, Knowler WC. A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array. Diabetes 2007;56:3045-3052 (Pubitemid 350223641)
-
(2007)
Diabetes
, vol.56
, Issue.12
, pp. 3045-3052
-
-
Hanson, R.L.1
Bogardus, C.2
Duggan, D.3
Kobes, S.4
Knowlton, M.5
Infante, A.M.6
Marovich, L.7
Benitez, D.8
Baier, L.J.9
Knowler, W.C.10
-
28
-
-
0034032564
-
Diabetes in the old order Amish: Characterization and heritability analysis of the Amish family diabetes study
-
Hsueh WC, Mitchell BD, Aburomia R, Pollin T, Sakul H, Gelder Ehm M, Michelsen BK, Wagner MJ, St Jean PL, Knowler WC, Burns DK, Bell CJ, Shuldiner AR. Jean PL, Knowler WC, Burns DK, Bell CJ, Shuldiner AR. Diabetes in the Old Order Amish: characterization and heritability analysis of the Amish Family Diabetes Study. Diabetes Care 2000;23:595-601 (Pubitemid 30321536)
-
(2000)
Diabetes Care
, vol.23
, Issue.5
, pp. 595-601
-
-
Hsueh, W.-C.1
Mitchell, B.D.2
Aburomia, R.3
Pollin, T.4
Sakul, H.5
Ehm, M.G.6
Michelsen, B.K.7
Wagner, M.J.8
St Jean, P.L.9
Knowler, W.C.10
Burns, D.K.11
Bell, C.J.12
Shuldiner, A.R.13
-
29
-
-
34249846721
-
TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children
-
DOI 10.1210/jc.2006-2514
-
Körner A, Berndt J, Stumvoll M, Kiess W, Kovacs P. TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children. J Clin Endocrinol Metab 2007;92:1956-1960 (Pubitemid 46997217)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.5
, pp. 1956-1960
-
-
Korner, A.1
Berndt, J.2
Stumvoll, M.3
Kiess, W.4
Kovacs, P.5
-
31
-
-
0033909546
-
A general test of association for quantitative traits in nuclear families
-
Abecasis GR, Cardon LR, Cookson WO. A general test of association for quantitative traits in nuclear families. Am J Hum Genet 2000;66:279-292
-
(2000)
Am J Hum Genet
, vol.66
, pp. 279-292
-
-
Abecasis, G.R.1
Cardon, L.R.2
Cookson, W.O.3
-
32
-
-
0035516193
-
Changes in BMI and weight before and after the development of type 2 diabetes
-
Looker HC, Knowler WC, Hanson RL. Changes in BMI and weight before and after the development of type 2 diabetes. Diabetes Care 2001;24:1917-1922 (Pubitemid 33716501)
-
(2001)
Diabetes Care
, vol.24
, Issue.11
, pp. 1917-1922
-
-
Looker, H.C.1
Knowler, W.C.2
Hanson, R.L.3
-
33
-
-
0022468357
-
Individual admixture estimates: Disease associations and individual risk of diabetes and gallbladder disease among Mexican-Americans in Starr County, Texas
-
Hanis CL, Chakraborty R, Ferrell RE, Schull WJ. Individual admixture estimates: disease associations and individual risk of diabetes and gallbladder disease among Mexican-Americans in Starr County, Texas. Am J Phys Anthropol 1986;70:433-441
-
(1986)
Am J Phys Anthropol
, vol.70
, pp. 433-441
-
-
Hanis, C.L.1
Chakraborty, R.2
Ferrell, R.E.3
Schull, W.J.4
-
34
-
-
34250861441
-
A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping
-
DOI 10.1086/513522
-
Tian C, Hinds DA, Shigeta R, Adler SG, Lee A, Pahl MV, Silva G, Belmont JW, Hanson RL, Knowler WC, Gregersen PK, Ballinger DG, Seldin MF. A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping. Am J Hum Genet 2007;80:1014-1023 (Pubitemid 47579339)
-
(2007)
American Journal of Human Genetics
, vol.80
, Issue.6
, pp. 1014-1023
-
-
Tian, C.1
Hinds, D.A.2
Shigeta, R.3
Adler, S.G.4
Lee, A.5
Pahl, M.V.6
Silva, G.7
Belmont, J.W.8
Hanson, R.L.9
Knowler, W.C.10
Gregersen, P.K.11
Ballinger, D.G.12
Seldin, M.F.13
-
35
-
-
2042495471
-
Statistical methods in meta-analysis
-
Petitti DB, Ed. Oxford, U.K., Oxford University Press
-
Petitti DB. Statistical methods in meta-analysis. In Meta-Analysis, Decision Analysis and Cost-Effectiveness Analysis: Methods for Quantitative Synthesis in Medicine. Petitti DB, Ed. Oxford, U.K., Oxford University Press, 2000, p. 94-118
-
(2000)
Meta-Analysis, Decision Analysis and Cost-Effectiveness Analysis: Methods for Quantitative Synthesis in Medicine
, pp. 94-118
-
-
Petitti, D.B.1
-
36
-
-
78649317731
-
How the volumes were produced
-
Princeton, NJ, Princeton University Press
-
Stouffer SA, Suchman EA, DaVinney LC, Star SA, Williams RM. How the volumes were produced. In The American Soldier, Volume I: Adjustment to Army Life. Princeton, NJ, Princeton University Press, 1949, p. 45
-
(1949)
The American Soldier, Volume I: Adjustment to Army Life
, pp. 45
-
-
Stouffer, S.A.1
Suchman, E.A.2
DaVinney, L.C.3
Star, S.A.4
Williams, R.M.5
-
37
-
-
2442710558
-
Subcutaneous abdominal preadipocyte differentiation in vitro inversely correlates with central obesity
-
Permana PA, Nair S, Lee YH, Luczy-Bachman G, Vozarova De Courten B, Tataranni PA. Subcutaneous abdominal preadipocyte differentiation in vitro inversely correlates with central obesity. Am J Physiol Endocrinol Metab 2004;286:E958-E962
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Permana, P.A.1
Nair, S.2
Lee, Y.H.3
Luczy-Bachman, G.4
Vozarova De Courten, B.5
Tataranni, P.A.6
-
38
-
-
24944489239
-
Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: Increased expression of inflammation-related genes
-
DOI 10.1007/s00125-005-1867-3
-
Lee YH, Nair S, Rousseau E, Allison DB, Page GP, Tataranni PA, Bogardus C, Permana PA. Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes. Diabetologia 2005;48:1776-1783 (Pubitemid 41317831)
-
(2005)
Diabetologia
, vol.48
, Issue.9
, pp. 1776-1783
-
-
Lee, Y.H.1
Nair, S.2
Rousseau, E.3
Allison, D.B.4
Page, G.P.5
Tataranni, P.A.6
Bogardus, C.7
Permana, P.A.8
-
39
-
-
42249087793
-
Estimation of significance thresholds for genomewide association scans
-
Dudbridge F, Gusnanto A. Estimation of significance thresholds for genomewide association scans. Genet Epidemiol 2008;32:227-234
-
(2008)
Genet Epidemiol
, vol.32
, pp. 227-234
-
-
Dudbridge, F.1
Gusnanto, A.2
-
41
-
-
70350536554
-
Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy
-
Pezzolesi MG, Katavetin P, Kure M, Poznik GD, Skupien J, Mychaleckyj JC, Rich SS, Warram JH, Krolewski AS. Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy. Diabetes 2009;58:2698-2702
-
(2009)
Diabetes
, vol.58
, pp. 2698-2702
-
-
Pezzolesi, M.G.1
Katavetin, P.2
Kure, M.3
Poznik, G.D.4
Skupien, J.5
Mychaleckyj, J.C.6
Rich, S.S.7
Warram, J.H.8
Krolewski, A.S.9
-
42
-
-
60549099209
-
Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans
-
Leak TS, Perlegas PS, Smith SG, Keene KL, Hicks PJ, Langefeld CD, Mychaleckyj JC, Rich SS, Kirk JK, Freedman BI, Bowden DW, Sale MM. Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans. Ann Hum Genet 2009;73:152-159
-
(2009)
Ann Hum Genet
, vol.73
, pp. 152-159
-
-
Leak, T.S.1
Perlegas, P.S.2
Smith, S.G.3
Keene, K.L.4
Hicks, P.J.5
Langefeld, C.D.6
Mychaleckyj, J.C.7
Rich, S.S.8
Kirk, J.K.9
Freedman, B.I.10
Bowden, D.W.11
Sale, M.M.12
-
43
-
-
20144388376
-
Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy
-
DOI 10.2337/diabetes.54.4.1171
-
Shimazaki A, Kawamura Y, Kanazawa A, Sekine A, Saito S, Tsunoda T, Koya D, Babazono T, Tanaka Y, Matsuda M, Kawai K, Iiizumi T, Imanishi M, Shinosaki T, Yanagimoto T, Ikeda M, Omachi S, Kashiwagi A, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakajima M, Nakamura Y, Maeda S. Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy. Diabetes 2005;54:1171-1178 (Pubitemid 40446333)
-
(2005)
Diabetes
, vol.54
, Issue.4
, pp. 1171-1178
-
-
Shimazaki, A.1
Kawamura, Y.2
Kanazawa, A.3
Sekine, A.4
Saito, S.5
Tsunoda, T.6
Koya, D.7
Babazono, T.8
Tanaka, Y.9
Matsuda, M.10
Kawai, K.11
Iiizumi, T.12
Imanishi, M.13
Shinosaki, T.14
Yanagimoto, T.15
Ikeda, M.16
Omachi, S.17
Kashiwagi, A.18
Kaku, K.19
Iwamoto, Y.20
Kawamori, R.21
Kikkawa, R.22
Nakajima, M.23
Nakamura, Y.24
Maeda, S.25
more..
-
44
-
-
51949111100
-
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2
-
Zhang C, Zhang Z, Castle J, Sun S, Johnson J, Krainer AR, Zhang MQ. Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev 2008;22:2550-2563
-
(2008)
Genes Dev
, vol.22
, pp. 2550-2563
-
-
Zhang, C.1
Zhang, Z.2
Castle, J.3
Sun, S.4
Johnson, J.5
Krainer, A.R.6
Zhang, M.Q.7
-
45
-
-
58049161508
-
Roles of eukaryotic Lsm proteins in the regulation of mRNA function
-
Tharun S. Roles of eukaryotic Lsm proteins in the regulation of mRNA function. Int Rev Cell Mol Biol 2009;272:149-189
-
(2009)
Int Rev Cell Mol Biol
, vol.272
, pp. 149-189
-
-
Tharun, S.1
-
46
-
-
57449116963
-
Ataxin-2 associates with rough endoplasmic reticulum
-
van de Loo S, Eich F, Nonis D, Auburger G, Nowock J. Ataxin-2 associates with rough endoplasmic reticulum. Exp Neurol 2009;215:110-118
-
(2009)
Exp Neurol
, vol.215
, pp. 110-118
-
-
Van De Loo, S.1
Eich, F.2
Nonis, D.3
Auburger, G.4
Nowock, J.5
-
47
-
-
9644260563
-
Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes
-
Lin X, Taguchi A, Park S, Kushner JA, Li F, Li Y, White MF. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes. J Clin Invest 2004;114:908-916
-
(2004)
J Clin Invest
, vol.114
, pp. 908-916
-
-
Lin, X.1
Taguchi, A.2
Park, S.3
Kushner, J.A.4
Li, F.5
Li, Y.6
White, M.F.7
-
48
-
-
27544450765
-
Divergence of melanocortin pathways in the control of food intake and energy expenditure
-
Balthasar N, Dalgaard LT, Lee CE, Yu J, Funahashi H, Williams T, Ferreira M, Tang V, McGovern RA, Kenny CD, Christiansen LM, Edelstein E, Choi B, Boss O, Aschkenasi C, Zhang CY, Mountjoy K, Kishi T, Elmquist JK, Lowell BB. Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 2005;123:493-9505
-
(2005)
Cell
, vol.123
, pp. 493-9505
-
-
Balthasar, N.1
Dalgaard, L.T.2
Lee, C.E.3
Yu, J.4
Funahashi, H.5
Williams, T.6
Ferreira, M.7
Tang, V.8
McGovern, R.A.9
Kenny, C.D.10
Christiansen, L.M.11
Edelstein, E.12
Choi, B.13
Boss, O.14
Aschkenasi, C.15
Zhang, C.Y.16
Mountjoy, K.17
Kishi, T.18
Elmquist, J.K.19
Lowell, B.B.20
more..
|