A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction

Journal of Biological Chemistry

Volumn 285, Issue 44, 2010, Pages 33858-33866

  Pointon, Jonathan A ^a   Smith, Wendy D ^a   Saalbach, Gerhard ^b   Crow, Allister ^b   Kehoe, Michael A ^a   Banfield, Mark J ^b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL ADHESION; BACTERIAL PATHOGENS; CELL INTERACTION; COVALENT ATTACHMENT; GRAM-POSITIVE PATHOGENS; HOST CELLS; HUMAN PATHOGENS; ISOPEPTIDE BOND; NON-COVALENT INTERACTION; PROTEIN STABILITY; SIDE CHAINS; STREPTOCOCCUS PYOGENES; TARGET MOLECULE; THIOESTERS; UV VISIBLE SPECTROSCOPY;

ADHESION; AMINO ACIDS; BACTERIOLOGY; CELL ADHESION; MASS SPECTROMETRY; PATHOGENS; ULTRAVIOLET SPECTROSCOPY;

CRYSTAL STRUCTURE;

ADHESIN; CYSTEINE; GLUTAMINE; THIOESTER;

ARTICLE; BACTERIUM PILUS; CELL ADHESION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ESCHERICHIA COLI; GENE FREQUENCY; HOST CELL; MASS SPECTROMETRY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STABILITY; PROTEIN STRUCTURE; SPECTROSCOPY; STREPTOCOCCUS PYOGENES;

ADHESINS, BACTERIAL; ALLELES; ASPARTIC ACID; CELL ADHESION; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESTERS; FIMBRIAE, BACTERIAL; LYSINE; MUTAGENESIS; PEPTIDES; PROTEIN BINDING; SPECTROPHOTOMETRY, ULTRAVIOLET; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS PYOGENES;

EID: 77958613852     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.149385     Document Type: Article

References (51)

1. Mandlik, A., Swierczynski, A., Das, A., and Ton-That, H. (2008) Trends Microbiol. 16, 33-40
2. Proft, T., and Baker, E. N. (2009) Cell Mol. Life Sci. 66, 613-635
3. Ton-That, H., and Schneewind, O. (2004) Trends Microbiol. 12, 228-234
4. Scott, J. R., and Zähner, D. (2006) Mol. Microbiol. 62, 320-330
5. Telford, J. L., Barocchi, M. A., Margarit, I., Rappuoli, R., and Grandi, G. (2006) Nat. Rev. Microbiol. 4, 509-519
6. Waksman, G., and Hultgren, S. J. (2009) Nat. Rev. Microbiol. 7, 765-774
7. Budzik, J. M., Oh, S. Y., and Schneewind, O. (2009) J. Biol. Chem. 284, 12989-12997
8. Swaminathan, A., Mandlik, A., Swierczynski, A., Gaspar, A., Das, A., and Ton-That, H. (2007) Mol. Microbiol. 66, 961-974
9. Ton-That, H., Marraffini, L. A., and Schneewind, O. (2004) Mol. Microbiol. 53, 251-261
10. Ton-That, H., and Schneewind, O. (2003) Mol. Microbiol. 50, 1429-1438
11. Budzik, J. M., Marraffini, L. A., Souda, P., Whitelegge, J. P., Faull, K. F., and Schneewind, O. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 10215-10220
12. Budzik, J. M., Poor, C. B., Faull, K. F., Whitelegge, J. P., He, C., and Schneewind, O. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 19992-19997
13. Kang, H. J., Coulibaly, F., Clow, F., Proft, T., and Baker, E. N. (2007) Science 318, 1625-1628
14. Kang, H. J., Paterson, N. G., Gaspar, A. H., Ton-That, H., and Baker, E. N. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 16967-16971
15. Kang, H. J., and Baker, E. N. (2009) J. Biol. Chem. 284, 20729-20737
16. Alegre-Cebollada, J., Badilla, C. L., and Fernández, J. M. (2010) J. Biol. Chem. 285, 11235-11242
17. Cunningham, M. W. (2000) Clin. Microbiol. Rev. 13, 470-511
18. Abbot, E. L., Smith, W. D., Siou, G. P., Chiriboga, C., Smith, R. J., Wilson, J. A., Hirst, B. H., and Kehoe, M. A. (2007) Cell Microbiol. 9, 1822-1833
19. Manetti, A. G., Zingaretti, C., Falugi, F., Capo, S., Bombaci, M., Bagnoli, F., Gambellini, G., Bensi, G., Mora, M., Edwards, A. M., Musser, J. M., Graviss, E. A., Telford, J. L., Grandi, G., and Margarit, I. (2007) Mol. Microbiol. 64, 968-983
20. Mora, M., Bensi, G., Capo, S., Falugi, F., Zingaretti, C., Manetti, A. G., Maggi, T., Taddei, A. R., Grandi, G., and Telford, J. L. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 15641-15646
21. Emsley, J., Knight, C. G., Farndale, R. W., Barnes, M. J., and Liddington, R. C. (2000) Cell 101, 47-56
22. Quigley, B. R., Zähner, D., Hatkoff, M., Thanassi, D. G., and Scott, J. R. (2009) Mol. Microbiol. 72, 1379-1394
23. Linke, C., Young, P. G., Kang, H. J., Bunker, R. D., Middleditch, M. J., Caradoc-Davies, T. T., Proft, T., and Baker, E. N. (2010) J. Biol. Chem. 285, 20381-20389
24. Race, P. R., Bentley, M. L., Melvin, J. A., Crow, A., Hughes, R. K., Smith, W. D., Sessions, R. B., Kehoe, M. A., McCafferty, D. G., and Banfield, M. J. (2009) J. Biol. Chem. 284, 6924-6933
25. Mandlik, A., Das, A., and Ton-That, H. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 14147-14152
26. Hilleringmann, M., Ringler, P., Müller, S. A., De Angelis, G., Rappuoli, R., Ferlenghi, I., and Engel, A. (2009) EMBO J. 28, 3921-3930
27. Izoré, T., Contreras-Martel, C., El Mortaji, L., Manzano, C., Terrasse, R., Vernet, T., Di Guilmi, A. M., and Dessen, A. (2010) Structure 18, 106-115
28. Law, S. K., and Dodds, A. W. (1997) Protein Sci. 6, 263-274
29. Leslie, A. G. (2006) Acta Crystallogr. D. Biol. Crystallogr. 62, 48-57
30. Evans, P. (2006) Acta Crystallogr. D. Biol. Crystallogr. 62, 72-82
31. Collaborative Computational Project, n. (1994) Acta Crystallogr. D. Biol. Crystallogr. 50, 760-763
32. Adams, P. D., Grosse-Kunstleve, R. W., Hung, L. W., Ioerger, T. R., Mc-Coy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C., Sauter, N. K., and Terwilliger, T. C. (2002) Acta Crystallogr. D. Biol. Crystallogr. 58, 1948-1954
33. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D. Biol. Crystallogr. 53, 240-255
34. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D. Biol. Crystallogr. 60, 2126-2132
35. Davis, I. W., Leaver-Fay, A., Chen, V. B., Block, J. N., Kapral, G. J., Wang, X., Murray, L. W., Arendall, W. B., 3rd, Snoeyink, J., Richardson, J. S., and Richardson, D. C. (2007) Nucleic Acids Res. 35, W375-W383
36. Kleywegt, G. J., Zou, J. Y., Kjeldgaard, M., and Jones, T. A. (2001) International Tables for Crystallography, Vol. F. Crystallography of Biological Macromolecules, Kluwer Academic Publishers, Dordrecht
37. Cox, J., and Mann, M. (2008) Nat. Biotechnol. 26, 1367-1372
38. Fontaine, M. C., Lee, J. J., and Kehoe, M. A. (2003) Infect. Immun. 71, 3857-3865
39. Berrow, N. S., Alderton, D., Sainsbury, S., Nettleship, J., Assenberg, R., Rahman, N., Stuart, D. I., and Owens, R. J. (2007) Nucleic Acids Res. 35, e45
40. Holm, L., Kääriäinen, S., Rosenström, P., and Schenkel, A. (2008) Bioinformatics 24, 2780-2781
41. Krishnan, V., Gaspar, A. H., Ye, N., Mandlik, A., Ton-That, H., and Narayana, S. V. (2007) Structure 15, 893-903
42. Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., and Gray, T. (1995) Protein Sci. 4, 2411-2423
43. Oke, M., Carter, L. G., Johnson, K. A., Liu, H., McMahon, S. A., Yan, X., Kerou, M., Weikart, N. D., Kadi, N., Sheikh, M. A., Schmelz, S., Dorward, M., Zawadzki, M., Cozens, C., Falconer, H., Powers, H., Overton, I. M., van Niekerk, C. A., Peng, X., Patel, P., Garrett, R. A., Prangishvili, D., Botting, C. H., Coote, P. J., Dryden, D. T., Barton, G. J., Schwarz-Linek, U., Challis, G. L., Taylor, G. L., White, M. F., and Naismith, J. H. (2010) J. Struct. Funct. Genomics 11, 167-180
44. Chu, C. T., and Pizzo, S. V. (1994) Lab. Invest. 71, 792-812
45. Cherry, S., and Silverman, N. (2006) Nat. Immunol. 7, 911-917
46. Pangburn, M. K. (1992) FEBS Lett. 308, 280-282
47. Janssen, B. J., Christodoulidou, A., McCarthy, A., Lambris, J. D., and Gros, P. (2006) Nature 444, 213-216
48. Janssen, B. J., Huizinga, E. G., Raaijmakers, H. C., Roos, A., Daha, M. R., Nilsson-Ekdahl, K., Nilsson, B., and Gros, P. (2005) Nature 437, 505-511
49. Dodds, A. W., Ren, X. D., Willis, A. C., and Law, S. K. (1996) Nature 379, 177-179
50. Sim, R. B., and Sim, E. (1981) Biochem. J. 193, 129-141
51. Smith, W. D., Pointon, J. A., Abbot, E., Kang, H. J., Baker, E. N., Hirst, B. H., Wilson, J. A., Banfield, M. J., and Kehoe, M. A. (2010) J. Bacteriol. 192, 4651-4659