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Volumn 30, Issue 9, 2010, Pages 3333-3339

Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells

Author keywords

Apoptosis; Prostate cancer; Prosurvival signaling proteins; Xanthohumol

Indexed keywords

ANNEXIN; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BCL 2; PROTEIN KINASE B; SURVIVIN; XANTHOHUMOL; ANTINEOPLASTIC AGENT; FLAVONOID; PLANT EXTRACT; PROPIOPHENONE DERIVATIVE;

EID: 77958563399     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (96)

References (26)
  • 1
    • 0030939099 scopus 로고    scopus 로고
    • Hormonal therapy in the management of prostate cancer: From Higgins to the present
    • Garnick MB: Hormonal therapy in the management of prostate cancer: From Higgins to the present. Urology 49: 5-15, 1997.
    • (1997) Urology , vol.49 , pp. 5-15
    • Garnick, M.B.1
  • 2
    • 0030455892 scopus 로고    scopus 로고
    • Long-term control of prostate cancer with radiation
    • Hanks GE: Long-term control of prostate cancer with radiation. Urol Clin North Amer 23: 605-616, 1996.
    • (1996) Urol Clin North Amer , vol.23 , pp. 605-616
    • Hanks, G.E.1
  • 3
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
    • Block G, Patterson B and Subar A: Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18: 1-29, 1992.
    • (1992) Nutr Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 5
    • 0032813348 scopus 로고
    • Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances
    • Surh Y: Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res 428: 305-327, 1995.
    • (1995) Mutat Res , vol.428 , pp. 305-327
    • Surh, Y.1
  • 6
    • 0033007552 scopus 로고    scopus 로고
    • Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry
    • Stevens JF, Taylor AW and Deinzer ML: Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry. J Chromatogr 832: 97-107, 1999.
    • (1999) J Chromatogr , vol.832 , pp. 97-107
    • Stevens, J.F.1    Taylor, A.W.2    Deinzer, M.L.3
  • 7
    • 3042559902 scopus 로고    scopus 로고
    • Xanthohumol and related prenylflavonoids from hops and beer: To your good health!
    • Stevens JF and Page JE: Xanthohumol and related prenylflavonoids from hops and beer: to your good health! Phytochemistry 65: 1317-1330, 2004.
    • (2004) Phytochemistry , vol.65 , pp. 1317-1330
    • Stevens, J.F.1    Page, J.E.2
  • 10
    • 33845611585 scopus 로고    scopus 로고
    • Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells
    • DOI 10.1016/j.canlet.2006.02.015, PII S0304383506001236
    • Colgate EC, Miranda CL, Stevens JF, Bray TM, Ho E. Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells. Cancer Lett 246: 201-209, 2006. (Pubitemid 44959390)
    • (2007) Cancer Letters , vol.246 , Issue.1-2 , pp. 201-209
    • Colgate, E.C.1    Miranda, C.L.2    Stevens, J.F.3    Bray, T.M.4    Ho, E.5
  • 12
    • 26244437262 scopus 로고    scopus 로고
    • Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway
    • Pan L, Becker H and Gerhauser C: Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway. Mol Nutr Food Res 49: 837-843, 2005.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 837-843
    • Pan, L.1    Becker, H.2    Gerhauser, C.3
  • 14
    • 33645814383 scopus 로고    scopus 로고
    • Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NFkappaB and Akt as targets
    • Albini A, Dell'Eva R, Vene R, Ferrari N, Buhler DR, Noonan DM and Fassina G: Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NFkappaB and Akt as targets. FASEB J 20: 527-529, 2006.
    • (2006) FASEB J , vol.20 , pp. 527-529
    • Albini, A.1    Dell'Eva, R.2    Vene, R.3    Ferrari, N.4    Buhler, D.R.5    Noonan, D.M.6    Fassina, G.7
  • 15
    • 36849093406 scopus 로고    scopus 로고
    • Inhibition of topoisomerase 1 activity and efflux drug transporter's expression by xanthohumol from hops
    • Lee SH, Kim HJ, Lee JS, Lee IS and Rang BY: Inhibition of topoisomerase 1 activity and efflux drug transporter's expression by xanthohumol from hops. Arch Pharm Res 30: 1435-1439, 2007.
    • (2007) Arch Pharm Res , vol.30 , pp. 1435-1439
    • Lee, S.H.1    Kim, H.J.2    Lee, J.S.3    Lee, I.S.4    Rang, B.Y.5
  • 16
    • 34547681712 scopus 로고    scopus 로고
    • Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupus L.) flavonoids
    • Monteiro R, Faria A, Azevedo I and Calhau C: Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupus L.) flavonoids. J Steroid Bioche Mol Biol 105: 124-130, 2007.
    • (2007) J Steroid Bioche Mol Biol , vol.105 , pp. 124-130
    • Monteiro, R.1    Faria, A.2    Azevedo, I.3    Calhau, C.4
  • 17
    • 35349001174 scopus 로고    scopus 로고
    • CDDO-Me induces apoptosis and inhibits Akt, mTOR and NF-κB signaling proteins in prostate cancer cells
    • Deeb D, Gao X, Jiang H, Arbab AS, Dulchavsky SA, and Gautam SC: CDDO-Me induces apoptosis and inhibits Akt, mTOR and NF-κB signaling proteins in prostate cancer cells. Anticancer Res 27: 3035-3044, 2007. (Pubitemid 47607524)
    • (2007) Anticancer Research , vol.27 , Issue.5 A , pp. 3035-3044
    • Deeb, D.1    Gao, X.2    Dulchavsky, S.A.3    Gautam, S.C.4
  • 20
    • 34848881624 scopus 로고    scopus 로고
    • Effects of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis
    • Yang J-Y, Della-Fera MA, Rayalam S and Baile CA: Effects of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis. Apoptosis 12: 1953-1963, 2007.
    • (2007) Apoptosis , vol.12 , pp. 1953-1963
    • Yang, J.-Y.1    Della-Fera, M.A.2    Rayalam, S.3    Baile, C.A.4
  • 21
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A and Dixit VM: Death receptors: Signaling and modulation. Science 281: 1305-1308, 1998.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 22
    • 0033582526 scopus 로고    scopus 로고
    • Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
    • DOI 10.1074/jbc.274.8.5053
    • Sun X-M, MacFarlane M, Zhuang J, Wolf BB, Green DR and Cohen GM: Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem 274: 5053-5060, 1999. (Pubitemid 29113412)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.8 , pp. 5053-5060
    • Sun, X.-M.1    MacFarlane, M.2    Zhuang, J.3    Wolf, B.B.4    Green, D.R.5    Cohen, G.M.6
  • 23
    • 0030884103 scopus 로고    scopus 로고
    • PKB/Akt: Connecting phosphoinositide3-kinase to cell survival and beyond
    • Marte BM and Downward J: PKB/Akt: connecting phosphoinositide3-kinase to cell survival and beyond. Trends Biochem Sci 22: 355-358, 1997.
    • (1997) Trends Biochem Sci , vol.22 , pp. 355-358
    • Marte, B.M.1    Downward, J.2
  • 24
    • 0034719680 scopus 로고    scopus 로고
    • The transcription factor NF-κB: Control of oncogenesis and cancer therapy resistance
    • Mayo MW and Baldwin AS: The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance. Biochim Biophys Acta 1470: M55-M62, 2000.
    • (2000) Biochim Biophys Acta , vol.1470
    • Mayo, M.W.1    Baldwin, A.S.2
  • 25
    • 0034722888 scopus 로고    scopus 로고
    • The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
    • DOI 10.1038/sj.onc.1204091
    • Hidalgo M and Rowinsky EK: The rapamycin-sensitive signal transduction pathway as a target for cancer therapy. Oncogene 19: 6680-6686, 2000. (Pubitemid 32197708)
    • (2000) Oncogene , vol.19 , Issue.56 , pp. 6680-6686
    • Hidalgo, M.1    Rowinsky, E.K.2
  • 26
    • 61949193344 scopus 로고    scopus 로고
    • Modification of the cysteine residues in I{kappa}B {alpha} kinase and NF-{kappa}B (p65) by xanthohumol leads to suppression of NF-{kappa}B-regulated gene products and potentiation of apoptosis in leukemia cells
    • Harikumar KB, Kunnumakkara AB, Ahn KS, Anand P, Krishnan S, Guha S and Aggarwal BB: Modification of the cysteine residues in I{kappa}B {alpha} kinase and NF-{kappa}B (p65) by xanthohumol leads to suppression of NF-{kappa}B-regulated gene products and potentiation of apoptosis in leukemia cells. Blood 113: 2003-2013, 2009.
    • (2009) Blood , vol.113 , pp. 2003-2013
    • Harikumar, K.B.1    Kunnumakkara, A.B.2    Ahn, K.S.3    Anand, P.4    Krishnan, S.5    Guha, S.6    Aggarwal, B.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.