The Lbc Rho guanine nucleotide exchange factor/α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation

Journal of Biological Chemistry

Volumn 285, Issue 43, 2010, Pages 32919-32926

  Bear, Michael D ^a   Li, Min ^a   Liu, Yinglin ^a   Giel Moloney, Maryann A ^b   Fanburg, Barry L ^a   Toksoz, Deniz ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL TYPES; EXTRACELLULAR SIGNALS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANINE NUCLEOTIDES; INTERVENTIONAL; MAP KINASE; MITOGENESIS; MITOGENIC; PULMONARY ARTERIAL HYPERTENSION; SERUM RESPONSE FACTORS; SMOOTH MUSCLE CELLS; VASCULAR SMOOTH MUSCLE CELLS; VASCULAR SMOOTH MUSCLES;

BLOOD VESSEL PROSTHESES; CELLS; CHEMICAL ACTIVATION; GROWTH KINETICS; NUCLEOTIDES; POSITIVE IONS; SIGNALING;

MUSCLE;

ALPHA CATULIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN LBC; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SEROTONIN; SERUM RESPONSE FACTOR; SMALL INTERFERING RNA; THYMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTERY MUSCLE; ARTICLE; CELL GROWTH; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PULMONARY ARTERY; REPORTER GENE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

A KINASE ANCHOR PROTEINS; ALPHA CATENIN; ANIMALS; CATTLE; CELL LINE; CELL PROLIFERATION; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGENS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTO-ONCOGENE PROTEINS; PULMONARY ARTERY; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SEROTONIN; SERUM RESPONSE FACTOR; VASCULAR DISEASES;

EID: 77958512355     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.062513     Document Type: Article

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