Loss of fibulin-2 expression is associated with breast cancer progression

American Journal of Pathology

Volumn 170, Issue 5, 2007, Pages 1535-1545

  Yi, Chun Hui ^a,b   Smith, David J ^b   West, William W ^b   Hollingsworth, Michael A ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBULIN; FIBULIN 2; MESSENGER RNA; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER TISSUE; CELL ADHESION; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; WOUND HEALING; BIOSYNTHESIS; BREAST TUMOR; CELL MOTION; DISEASE COURSE; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 34250815728     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.060478     Document Type: Article

References (41)

1. Kluge M, Mann K, Dziadek M, Timpl R: Characterization of a novel calcium-binding 90-kDa glycoprotein (BM-90) shared by basement membranes and serum. Eur J Biochem 1990, 193:651-659
2. Timpl R, Sasaki T, Kostka G, Chu ML: Fibulins: a versatile family of extracellular matrix proteins. Nat Rev Mol Cell Biol 2003, 4:479-489
3. Argraves WS, Greene LM, Cooley MA, Gallagher WM: Fibulins: physiological and disease perspectives. EMBO Rep 2003, 4:1127-1131
4. Watson RE, Griffiths CE: Fibulin-2 and its association with fibrillin-rich microfibrils in the papillary dermis of photoaged skin. Br J Dermatol 2002, 146:712
5. Hopf M, Gohring W, Mann K, Timpl R: Mapping of binding sites for nidogens, Fibulin-2, fibronectin and heparin to different IG modules of perlecan. J Mol Biol 2001, 311:529-541
6. Gu YC, Nilsson K, Eng H, Ekblom M: Association of extracellular matrix proteins Fibulin-1 and Fibulin-2 with fibronectin in bone marrow stroma. Br J Haematol 2000, 109:305-313
7. Olin AI, Morgelin M, Sasaki T, Timpl R, Heinegard D, Aspberg A: The proteoglycans aggrecan and versican form networks with Fibulin-2 through their lectin domain binding. J Biol Chem 2001, 276:1253-1261
8. Pan TC, Sasaki T, Zhang RZ, Fassler R, Timpl R, Chu ML: Structure and expression of Fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding. J Cell Biol 1993, 123:1269-1277
9. Zhang RZ, Pan TC, Zhang ZY, Mattei MG, Timpl R, Chu ML: Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes. Genomics 1994, 22:425-430
10. Sasaki T, Mann K, Wiedemann H, Gohring W, Lustig A, Engel J, Chu ML, Timpl R: Dimer model for the microfibrillar protein Fibulin-2 and identification of the connecting disulfide bridge. EMBO J 1997, 16:3035-3043
11. Sasaki T, Gohring W, Pan TC, Chu ML, Timpl R: Binding of mouse and human Fibulin-2 to extracellular matrix ligands. J Mol Biol 1995, 254:892-899
12. Utani A, Nomizu M, Yamada Y: Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences. J Biol Chem 1997, 272:2814-2820
13. Sasaki T, Wiedemann H, Matzner M, Chu ML, Timpl R: Expression of Fibulin-2 by fibroblasts and deposition with fibronectin into a fibrillar matrix. J Cell Sci 1996, 109:2895-2904
14. Chu ML, Tsuda T: Fibulins in development and heritable disease. Birth Defects Res C Embryo Today 2004, 72:25-36
15. Zhang HY, Chu ML, Pan TC, Sasaki T, Timpl R, Ekblom P: Extracellular matrix protein Fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart. Dev Biol 1995, 167:18-26
16. Miosge N, Gotz W, Sasaki T, Chu ML, Timpl R, Herken R: The extracellular matrix proteins Fibulin-1 and Fibulin-2 in the early human embryo. Histochem J 1996, 28:109-116
17. Fassler R, Sasaki T, Timpl R, Chu ML, Werner S: Differential regulation of Fibulin, tenascin-C, and nidogen expression during wound healing of normal and glucocorticoid-treated mice. Exp Cell Res 1996, 222:111-116
18. Lee MJ, Roy NK, Mogford JE, Schiemann WP, Mustoe TA: Fibulin-5 promotes wound healing in vivo. J Am Coll Surg 2004, 199:403-410
19. Roger P, Pujol P, Lucas A, Baldet P, Rochefort H: Increased immunostaining of Fibulin-1, an estrogen-regulated protein in the stroma of human ovarian epithelial tumors. Am J Pathol 1998, 153:1579-1588
20. Greene LM, Twal WO, Duffy MJ, McDermott EW, Hill AD, O'Higgins NJ, McCann AH, Dervan PA, Argraves WS, Gallagher WM: Elevated expression and altered processing of Fibulin-1 protein in human breast cancer. Br J Cancer 2003, 88:871-878
21. Gallagher WM, Greene LM, Ryan MP, Sierra V, Berger A, Laurent-Puig P, Conseiller E: Human Fibulin-4: analysis of its biosynthetic processing and mRNA expression in normal and tumour tissues. FEBS Lett 2001, 489:59-66
22. Schiemann WP, Blobe GC, Kalume DE, Pandey A, Lodish HF: Context-specific effects of Fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. J Biol Chem 2002, 277:27367-27377
23. Tsuda T, Wang H, Timpl R, Chu ML: Fibulin-2 expression marks transformed mesenchymal cells in developing cardiac valves, aortic arch vessels, and coronary vessels. Dev Dyn 2001, 222:89-100
24. Rauch U, Zhou XH, Roos G: Extracellular matrix alterations in brains lacking four of its components. Biochem Biophys Res Commun 2005, 328:608-617
25. Gallagher WM, Currid CA, Whelan LC: Fibulins and cancer: friend or foe? Trends Mol Med 2005, 11:336-340
26. Moll F, Katsaros D, Lazennec G, Hellio N, Roger P, Giacalone PL, Chalbos D, Maudelonde T, Rochefort H, Pujol P: Estrogen induction and overexpression of Fibulin-1C mRNA in ovarian cancer cells. Oncogene 2002, 21:1097-1107
27. Aerts JL, Gonzales MI, Topalian SL: Selection of appropriate control genes to assess expression of tumor antigens using real-time RT-PCR. Biotechniques 2004, 36:84-90
28. Sasaki T, Gohring W, Miosge N, Abrams WR, Rosenbloom J, Timpl R: Tropoelastin binding to Fibulins, nidogen-2 and other extracellular matrix proteins. FEBS Lett 1999, 460:280-284
29. Miosge N, Sasaki T, Timpl R: Angiogenesis inhibitor endostatin is a distinct component of elastic fibers in vessel walls. FASEB J 1999, 13:1743-1750
30. Pan TC, Kluge M, Zhang RZ, Mayer U, Timpl R, Chu ML: Sequence of extracellular mouse protein BM-90/Fibulin and its calcium-dependent binding to other basement-membrane ligands. Eur J Biochem 1993, 215:733-740
31. Hesselson D, Newman C, Kim KW, Kimble J: GON-1 and Fibulin have antagonistic roles in control of organ shape. Curr Biol 2004, 14:2005-2010
32. Kubota Y, Kuroki R, Nishiwaki K: A Fibulin-1 homolog interacts with an ADAM protease that controls cell migration in C. elegans. Curr Biol 2004, 14:2011-2018
33. Thompson EW, Paik S, Brunner N, Sommers CL, Zugmaier G, Clarke R, Shima TB, Torri J, Donahue S, Lippman ME, Martin GR, Dickson RB: Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 1992, 150:534-544
34. Lee NV, Rodriguez-Manzaneque JC, Thai SN, Twal WO, Luque A, Lyons KM, Argraves WS, Iruela-Arispe ML: Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem 2005, 280:34796-34804
35. Ström A, Olin AI, Aspberg A, Hultgardh-Nilsson A: Fibulin-2 is present in murine vascular lesions and is important for smooth muscle cell migration. Cardiovasc Res 2006, 69:755-763
36. Roark EF, Keene DR, Haudenschild CC, Godyna S, Little CD, Argraves WS: The association of human Fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study. J Histochem Cytochem 1995,43:401-411
37. Muriel JM, Dong C, Hutter H, Vogel BE: Fibulin-1C and Fibulin-1D splice variants have distinct functions and assemble in a hemicentin-dependent manner. Development 2005, 132:4223-4234
38. Qing J, Maher VM, Tran H, Argraves WS, Dunstan RW, McCormick JJ: Suppression of anchorage-independent growth and Matrigel invasion and delayed tumor formation by elevated expression of Fibulin-1D in human fibrosarcoma-derived cell lines. Oncogene 1997, 15:2159-2168
39. Twal WO, Czirok A, Hegedus B, Knaak C, Chintalapudi MR, Okagawa H, Sugi Y, Argraves WS: Fibulin-1 suppression of fibronectin-regulated cell adhesion and motility. J Cell Sci 2001, 114:4587-4598
40. Sherwood DR, Butler JA, Kramer JM, Sternberg PW: FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans. Cell 2005, 121:951-962
41. Bardin A, Moll F, Margueron R, Delfour C, Chu ML, Maudelonde T, Cavailles V, Pujol P: Transcriptional and posttranscriptional regulation of Fibulin-1 by estrogens leads to differential induction of messenger ribonucleic acid variants in ovarian and breast cancer cells. Endocrinology 2005, 146:760-768