-
2
-
-
0032772912
-
STAT signaling in the pathogenesis and treatment of cancer
-
Frank DA: STAT signaling in the pathogenesis and treatment of cancer. Mol Med 5: 432-456, 1999.
-
(1999)
Mol Med
, vol.5
, pp. 432-456
-
-
Frank, D.A.1
-
3
-
-
28544438023
-
Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
-
Haura EB, Zheng Z, Song L, Cantor A and Bepler G: Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res 11: 8288-8894, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8288-8894
-
-
Haura, E.B.1
Zheng, Z.2
Song, L.3
Cantor, A.4
Bepler, G.5
-
4
-
-
33645506849
-
Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung mutations of the epidermal growth factor receptor
-
Alvarez JV, Greulich H, Sellers WR, Meyerson M and Frank DA: Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung mutations of the epidermal growth factor receptor. Cancer Res 66: 3162-3168, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 3162-3168
-
-
Alvarez, J.V.1
Greulich, H.2
Sellers, W.R.3
Meyerson, M.4
Frank, D.A.5
-
5
-
-
1042302005
-
The STATs of cancer - new molecular targets come of age
-
Yu H and Jove R: The STATs of cancer - new molecular targets come of age. Nat Rev 4: 97-105, 2004.
-
(2004)
Nat Rev
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
6
-
-
19444385692
-
Stat3 regulates genes common to both wound healing and cancer
-
Dauer DJ, Ferraro B, Song L, et al: Stat3 regulates genes common to both wound healing and cancer. Oncogene 24: 3397-3408, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 3397-3408
-
-
Dauer, D.J.1
Ferraro, B.2
Song, L.3
-
7
-
-
0035794196
-
A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells
-
Gaemers IC, Vos HL, Volders HH, van der Valk SW and Hilkens J: A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells. J Biol Chem 276: 6191-6199, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 6191-6199
-
-
Gaemers, I.C.1
Vos, H.L.2
Volders, H.H.3
van der Valk, S.W.4
Hilkens, J.5
-
8
-
-
6344276574
-
Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells
-
Yuan ZL, Guan YJ, Wang L, Wei W, Kane AB and Chin YE: Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells. Mol Cell Biol 24: 9390-9400, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9390-9400
-
-
Yuan, Z.L.1
Guan, Y.J.2
Wang, L.3
Wei, W.4
Kane, A.B.5
Chin, Y.E.6
-
9
-
-
0021740104
-
Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
-
Kufe D, Inghirami G, Abe M, Hayes D, Justi-Wheeler H and Schlom J: Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 3: 223-232, 1984.
-
(1984)
Hybridoma
, vol.3
, pp. 223-232
-
-
Kufe, D.1
Inghirami, G.2
Abe, M.3
Hayes, D.4
Justi-Wheeler, H.5
Schlom, J.6
-
10
-
-
26944486309
-
Muc1 affects c-Src signaling in PyV MT-induced mammary tumorigenesis
-
Al Masri A and Gendler SJ: Muc1 affects c-Src signaling in PyV MT-induced mammary tumorigenesis. Oncogene 24: 5799-5808, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 5799-5808
-
-
Al Masri, A.1
Gendler, S.J.2
-
11
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
Li Y, Liu D, Chen D, Kharbanda S and Kufe D: Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22: 6107-6110, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
Kharbanda, S.4
Kufe, D.5
-
12
-
-
4143099166
-
MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation
-
Schroeder JA, Masri AA, Adriance MC, et al: MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation. Oncogene 23: 5739-5747, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 5739-5747
-
-
Schroeder, J.A.1
Masri, A.A.2
Adriance, M.C.3
-
13
-
-
0029439345
-
Analysis of mammalian MUC1 genes reveals potential functionally important domains
-
Spicer AP, Duhig T, Chilton BS and Gendler SJ: Analysis of mammalian MUC1 genes reveals potential functionally important domains. Mamm Genome 6: 885-888, 1995.
-
(1995)
Mamm Genome
, vol.6
, pp. 885-888
-
-
Spicer, A.P.1
Duhig, T.2
Chilton, B.S.3
Gendler, S.J.4
-
14
-
-
0031777599
-
Increased invasiveness of MUC1 and cDNA-transfected human gastric cancer MKN74 cells
-
Suwa T, Hinoda Y, Makiguchi Y, et al: Increased invasiveness of MUC1 and cDNA-transfected human gastric cancer MKN74 cells. Int J Cancer 76: 377-382, 1998.
-
(1998)
Int J Cancer
, vol.76
, pp. 377-382
-
-
Suwa, T.1
Hinoda, Y.2
Makiguchi, Y.3
-
15
-
-
0031723707
-
Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin
-
Li Y, Bharti A, Chen D, Gong J and Kufe D: Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin. Mol Cell Biol 18: 7216-7224, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7216-7224
-
-
Li, Y.1
Bharti, A.2
Chen, D.3
Gong, J.4
Kufe, D.5
-
16
-
-
0035794215
-
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin
-
Li Y, Kuwahara H, Ren J, Wen G and Kufe D: The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin. J Biol Chem 276: 6061-6064, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 6061-6064
-
-
Li, Y.1
Kuwahara, H.2
Ren, J.3
Wen, G.4
Kufe, D.5
-
17
-
-
0035929643
-
The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin
-
Li Y, Ren J, Yu W, et al: The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin. J Biol Chem 276: 35239-35242, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 35239-35242
-
-
Li, Y.1
Ren, J.2
Yu, W.3
-
18
-
-
0029160043
-
Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein
-
Pandey P, Kharbanda S and Kufe D: Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein. Cancer Res 55: 4000-4003, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 4000-4003
-
-
Pandey, P.1
Kharbanda, S.2
Kufe, D.3
-
19
-
-
0035918199
-
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
-
Schroeder JA, Thompson MC, Gardner MM and Gendler SJ: Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J Biol Chem 276: 13057-13064, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 13057-13064
-
-
Schroeder, J.A.1
Thompson, M.C.2
Gardner, M.M.3
Gendler, S.J.4
-
20
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion
-
Yamamoto M, Bharti A, Li Y and Kufe D: Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion. J Biol Chem 272: 12492-12494, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
Kufe, D.4
-
21
-
-
2442693937
-
The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
-
Raina D, Kharbanda S and Kufe D: The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J Biol Chem 279: 20607-20612, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 20607-20612
-
-
Raina, D.1
Kharbanda, S.2
Kufe, D.3
-
22
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
-
Ren J, Agata N, Chen D, et al: Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell 5: 163-175, 2004.
-
(2004)
Cancer Cell
, vol.5
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
-
23
-
-
30044445260
-
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90
-
Ren J, Bharti A, Raina D, Chen W, Ahmad R and Kufe D: MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90. Oncogene 25: 20-31, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 20-31
-
-
Ren, J.1
Bharti, A.2
Raina, D.3
Chen, W.4
Ahmad, R.5
Kufe, D.6
-
24
-
-
15144341821
-
Depolarized expression of episialin (EMA, MUC1) in lung adenocarcinoma is associated with tumor progression
-
Guddo F, Giatromanolaki A, Patriarca C, et al: Depolarized expression of episialin (EMA, MUC1) in lung adenocarcinoma is associated with tumor progression. Anticancer Res 18: 1915-1920, 1998.
-
(1998)
Anticancer Res
, vol.18
, pp. 1915-1920
-
-
Guddo, F.1
Giatromanolaki, A.2
Patriarca, C.3
-
25
-
-
34248573808
-
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products
-
Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J and Aggarwal BB: Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res 67: 3853-3861, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 3853-3861
-
-
Kunnumakkara, A.B.1
Guha, S.2
Krishnan, S.3
Diagaradjane, P.4
Gelovani, J.5
Aggarwal, B.B.6
-
26
-
-
11044230487
-
Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells
-
Gao J, Niwa K, Sun W, et al: Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells. Cancer Sci 95: 901-907, 2004.
-
(2004)
Cancer Sci
, vol.95
, pp. 901-907
-
-
Gao, J.1
Niwa, K.2
Sun, W.3
-
27
-
-
33745243692
-
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
-
Song L, Morris M, Bagui T, Lee FY, Jove R and Haura EB: Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res 66: 5542-5548, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 5542-5548
-
-
Song, L.1
Morris, M.2
Bagui, T.3
Lee, F.Y.4
Jove, R.5
Haura, E.B.6
-
28
-
-
35848932779
-
Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice
-
Wu W, O'Reilly MS, Langley RR, et al: Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice. Mol Cancer Ther 6: 2652-2663, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2652-2663
-
-
Wu, W.1
O'Reilly, M.S.2
Langley, R.R.3
-
30
-
-
33646355721
-
Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants
-
Liddle FJ, Alvarez JV, Poli V and Frank DA: Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants. Biochemistry 45: 5599-5605, 2006.
-
(2006)
Biochemistry
, vol.45
, pp. 5599-5605
-
-
Liddle, F.J.1
Alvarez, J.V.2
Poli, V.3
Frank, D.A.4
-
31
-
-
14844366111
-
ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive nonsmall cell lung cancer cell lines
-
Engelman JA, Janne PA, Mermel C, et al: ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive nonsmall cell lung cancer cell lines. Proc Natl Acad Sci USA 2: 3788-3793, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.2
, pp. 3788-3793
-
-
Engelman, J.A.1
Janne, P.A.2
Mermel, C.3
-
32
-
-
0345060457
-
Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice
-
Onn A, Isobe T, Itasaka S, et al: Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice. Clin Cancer Res 9: 5532-5539, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5532-5539
-
-
Onn, A.1
Isobe, T.2
Itasaka, S.3
-
33
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg J and Darnell JE Jr: The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19: 2468-2473, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell Jr, J.E.2
-
34
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
Rikova K, Guo A, Zeng Q, et al: Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131: 1190-1203, 2007.
-
(2007)
Cell
, vol.131
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
-
35
-
-
34347217519
-
MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells
-
Siragusa M, Zerilli M, Iovino F, et al: MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells. Cancer Res 67: 5522-5530, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 5522-5530
-
-
Siragusa, M.1
Zerilli, M.2
Iovino, F.3
|