Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis

BMC Gastroenterology

Volumn 10, Issue , 2010, Pages

  Martínez Carrillo, Dinorah N ^a   Garza González, Elvira ^b   Betancourt Linares, Reyes ^c   Mónico Manzano, Trinidad ^a   Antúnez Rivera, Cuauhtémoc ^a   Román Román, Adolfo ^a   Flores Alfaro, Eugenia ^a   Illades Aguiar, Berenice ^a   Fernández Tilapa, Gloria ^a  

^a UNIVERSIDAD AUTÓNOMA DE GUERRERO   (Mexico)

^b Medicina UANL   (Mexico)

^c Unidad Especializada en Gastroenterología Endoscopia Privada de Jacarandas No 5   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 1BETA; BACTERIAL DNA; BACTERIAL PROTEIN; DNA; IL1B PROTEIN, HUMAN; VACA PROTEIN, HELICOBACTER PYLORI;

ADOLESCENT; ADULT; AGE; AGED; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; BACTERIAL GENE; CHILD; CHRONIC GASTRITIS; CONTROLLED STUDY; DYSPEPSIA; EDUCATIONAL STATUS; FAMILY HISTORY; FEMALE; GENDER; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENOTYPE; GEOGRAPHIC ORIGIN; HAPLOTYPE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEXICO; POLYMERASE CHAIN REACTION; PYROSEQUENCING; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SCHOOL CHILD; SEROPREVALENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING HABIT; STOMACH ANTRUM; STOMACH BIOPSY; STOMACH ULCER; VACA GENE; BIOPSY; CHRONIC DISEASE; COMPARATIVE STUDY; GASTRITIS; GENETIC POLYMORPHISM; GENETICS; INCIDENCE; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MIDDLE AGED; RETROSPECTIVE STUDY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL PROTEINS; BIOPSY; CHRONIC DISEASE; DNA; DNA, BACTERIAL; FEMALE; GASTRITIS; HAPLOTYPES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INCIDENCE; INTERLEUKIN-1BETA; MALE; MEXICO; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES; STOMACH ULCER; YOUNG ADULT;

EID: 77958488365     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-10-126     Document Type: Article

References (47)

1. Rad R, Prinz C, Neu B, Neuhofer M, Zeitner Voland P, Becker I, Schepp W, Gerhard M. Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa. JID 2003, 188:272-280. 10.1086/376458, 12854083.
2. Sierra R, Une C, Ramírez V, Alpízar-Alpízar W, González MI, Ramírez JA, De Mascarel A, Cuenca P, Pérez-Pérez G, Mégraud F. Relation of atrophic gastritis with Helicobacter pylori-CagA+ and interleukin-1 gene polymorphisms. World J Gastroenterol 2008, 14:6481-6487. 10.3748/wjg.14.6481, 2773333, 19030199.
3. Fox JG, Wang TC. Inflammation, atrophy, and gastric cancer. J Clin Invest 2007, 117:60-69. 10.1172/JCI30111, 1716216, 17200707.
4. Peek RM, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nature 2002, 2:28-37.
5. Zhang Z, Zheng Q, Chen X, Xiao S, Liu W, Lu H. The Helicobacter pylori duodenal ulcer promoting gene, dupA in China. BMC Gastroenterology 2008, 8:49. 10.1186/1471-230X-8-49, 2584642, 18950522.
6. Garza-González E, Bosques-Padilla FJ, El-Omar E, Hold G, Tijerina-Menchaca R, Maldonado-Garza HJ, Pérez-Pérez GI. Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico. Int J Cancer 2005, 114:237-241. 10.1002/ijc.20718, 15540224.
7. Marciorkowska E, Roszko I, Kowalczuk O, Kaczmarski M, Chyczewski L, Kemona A. The evaluation of vacA gene allele frequency in Helicobacter pylori strains in adults and children in Podlaskies region. Folia Histochem Cytobiol 2007, 45:215-219.
8. Caricio-Martins L, Oliveira-Corvelo TC, Demachki S, Araujo MTF, Baraúna-Assumpção M, Araujo-Jucá Vilar SC, Bonfim-Freitas F, Melo-Barbosa HP, Alves-Fecury A, Kelly-Costa do Amaral R, Batista-dos Santos SE. Clinical and pathological importance of vacA allele heterogeneity and cagA status in peptic ulcer disease in patients from North Brazil. Mem Inst Oswaldo Cruz 2005, 100:875-881.
9. Chang YH, Wang L, Lee MS, Cheng CW, Wu CY, Shiau MY. Genotypic characterization of Helicobacter pylori cagA and vacA from biopsy specimens of patients with gastroduodenal diseases. Mt Sinai J Med 2006, 73:622-626.
10. Garza-González E, Bocanegra-García V, Bosques-Padilla FJ, Flores-Gutiérrez JP, Moreno F, Perez-Perez GI. mRNA levels of TLR4 and TLR5 are independent of H pylori. World J Gastroenterol 2008, 14:5306-5310. 10.3748/wjg.14.5306, 2744061, 18785283.
11. Moorchung N, Srivastava AN, Gupta NK, Ghoshal UC, Achyut BR, Mittal B. Cytokine gene polymorphisms and the pathology of chronic gastritis. Singapore Med J 2007, 48:447-454.
12. Kim SH, Mok JW, Kim HS, Joo CK. Association of -31T>C and -511 C>T polymorphisms in the interleukin 1 beta IL1B) promoter in Korean keratoconus patients. Mol Vis 2008, 14:2109-2116. 2588426, 19043479.
13. Uno M, Hamajima N, Ito LS, Oba S, Marie SKN, Shinjo SK, Onda H, Saito T, Takezaki T, Tajima K, Tominaga S. Helicobacter pylori seropositivity and IL-1B C-31T polymorphism among Japanese Brazilians. Int J Mol Med 2002, 10:321-326.
14. Kato S, Onda M, Yamada S, Matsuda N, Tokunaga A, Matsukura N. Association of the interleukin-1β genetic polymorphism and gastric cancer risk in Japanese. J Gastroenterol 2001, 36:696-9. 10.1007/s005350170033, 11686480.
15. Santtila S, Savinainen K, Hurme M. Presence of the IL-1RA allele 2 (IL1RN2) is associated with enhanced IL-1β production in vitro. Scand J Immunol 1998, 47:195-198. 10.1046/j.1365-3083.1998.00300.x, 9519856.
16. Hsu PI, Li CN, Tseng HH, Lai KH, Hsu PN, Lo GH, Lo CC, Yeh JJ, Ger LP, Hsiao M, Yamoaka Y, Hwang IR, Chen A. The Interleukin-I RN polymorphism and Helicobacter pylori infection in the development of duodenal ulcer. Helicobacter 2004, 9:604-613.
17. Al-Moundhri MS, Al-Nabhani M, Al-Bahrani B, Burney IA, Al-Madhani A, Ganguly SS, Al-Yahyaee SA, Grant CS. Interleukin-1β gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms and gastric cancer risk in an Omani Arab population. Gastric Cancer 2006, 9:284-290. 10.1007/s10120-006-0392-5, 17235630.
18. El-Omar EM. The importance of interleukin 1β in Helicobacter pylori associated disease. Gut 2001, 48:743-747. 10.1136/gut.48.6.743, 1728311, 11358884.
19. Figueiredo C, Machado JC, Pharoah P, Seruca R, Sousa S, Carvalho R, Capelinha AF, Quint W, Caldas C, van Dooorn LJ, Carneiro F, Sobrinho-Simoes M. Helicobater pylori and Interleukin 1 genotyping: An opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst 2002, 94:1680-1686.
20. Pérez-Pérez GI, Garza-González E, Portal C, Olivares AZ. Role of cytokine polymorphisms in the risk of distal gastric cancer development. Cancer Epidemiol Biomarkers Prev 2005, 14:1869-73. 10.1158/1055-9965.EPI-04-0889, 16103428.
21. Secretaría de Salud, Subsecretaría de Prevención y Promoción de la Salud. Centro Nacional de Vigilancia Epidemiológica y Control de Enfermedades. Dirección General de Epidemiología Información epidemiológica de morbilidad. México 2006, Secretaría de Salud, Subsecretaría de Prevención y Promoción de la Salud. Centro Nacional de Vigilancia Epidemiológica y Control de Enfermedades. Dirección General de Epidemiología.
22. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney system-International workshop on the histopathology of gastritis, Houston 1994. Am J Surg Pathol 1996, 20:1161-1181. 10.1097/00000478-199610000-00001, 8827022.
23. Sambrook J, Russel D. Molecular Cloning a Laboratory Manual 2001, EU: Col Spring Harbor Laboratory Press.
24. Atherton JC, Cao P, Peek RMR, Tummuru MKR, Blasser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J Biol Chem 1995, 270:17771-17777. 10.1074/jbc.270.30.17771, 7629077.
25. Park CY, Kwak M, Gutierrez O, Graham DY, Yamaoka Y. Comparison of genotyping Helicobacter pylori directly from biopsy specimens and genotyping from bacterial cultures. J Clin Microbiol 2003, 41:3336-3338. 10.1128/JCM.41.7.3336-3338.2003, 165374, 12843087.
26. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988, 16:1215. 10.1093/nar/16.3.1215, 334765, 3344216.
27. Pérez-Pérez GI, Portal-Celhay C, Bosques-Padilla FJ, Garza-González E. Desarrollo de un protocolo de pirosecuenciación para la tipificación del polimorfismo -31 del gen de la interleucina 1β en el estudio del riesgo al desarrollo de cáncer gástrico. Rev Gastroenterol Mex 2007, 72:136-140.
28. Morales-Espinoza R, Castillo-Rojas G, Gonzalez-Valencia G, Ponce-DeLeon S, Cravioto A, Atherton JC, López-Vidal Y. Colonization of Mexican patients by multiple Helicobacter pylori strains with different vacA and cagA genotypes. J Clin Microbiol 1999, 3001-3004. 85434, 10449490.
29. Garza-González E, Bosques-Padilla FJ, Tijerina-Menchaca R, Pérez-Pérez GI. Characterisation of Helicobacter pylori isolates from the north-eastern region of Mexico. Clin Microbiol Infect 2004, 10:41-45. 10.1111/j.1469-0691.2004.00731.x, 14706085.
30. Paniagua GL, Monroy E, Rodríguez R, Arroniz S, Rodríguez C, Cortés JL, Camacho A, Negrete E, Vaca S. Frequency of vacA, cagA and babA2 virulence markers in Helicobacter pylori strains isolated from Mexican patients with chronic gastritis. Ann Clin Microbiol Antimicrob 2009, 8:14. 10.1186/1476-0711-8-14, 2683802, 19405980.
31. Ruzzo A, Graziano F, Pizzagalli F, Santini D, Battistelli V, Panunzi S, Canestrari E, Catalano V, Humar B, Ficarelli R, Bearzi I, Cascinu S, Naldi N, Testa E, Magnani M. Interleukin 1B gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms in Helicobacter pylori-negative gastric cancer of intestinal and diffuse histotype. Ann Oncol 2005, 16:887-92. 10.1093/annonc/mdi184, 15851404.
32. El-Omar EM, Carrington M, Chow WH, McColl KE, Breamk JH, Young HA, Herrera J, Lissowska J, Yuan CC, Rothman N, Lanyon G, Martin M, Fraumeni JF, Rabkin CS. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 2000, 404:398-402. 10.1038/35006081, 10746728.
33. Chang YW, Jang JY, Kim NH, Won-Lee J, Jung-Lee J, Won-Jung W, Dong SH, Kim HJ, Kim BH, Lee JI, Chang R. Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1β cytokine in Korean patients with gastric cancer. Int J Cancer 2005, 114:465-471. 10.1002/ijc.20724, 15551344.
34. Kamangar F, Cheng C, Abnet CC, Rabkin CS. Interleukin-1B polymorphisms and gastric cancer risk--a meta-analysis. Cancer Epidemiol Biomarkers Prev 2006, 15:1920-8. 10.1158/1055-9965.EPI-06-0267, 17035400.
35. Prinz C, Schwendy Voland P. H. pylori and gastric cancer: Shifting the global burden. World J Gastroenterology 2006, 12(Suppl 34):5458-5464.
36. Saijo Y, Yoshioka E, Fukui T, Kawaharada M, Sata F, Sato H, Kishi R. H pylori seropositivity and cytokine gene polymorphisms. World J Gastroenterol 2007, 13:4445-4451.
37. Matsukura N, Yamada S, Kato S, Tomtitchong P, Tajiri T, Miki M, Matsuhisa T, Yamada N. Genetic differences in interleukin-1 beta polymorphisms among four Asian populations: An analysis of the Asian paradox between H. pylori infection and gastric cancer incidence. J Exp Clin Cancer Res 2003, 22:47-55.
38. Yamada S, Matsuhisa T, Makonkawkeyoon L, Chaidatch S, Kato S, Matsukura N. Helicobacter pylori infection in combination with the serum pepsinogen I/II ratio and interleukin-1b-511 polymorphisms are independent risk factors for gastric cancer in Thais. J Gastroenterol 2006, 41:1169-1177. 10.1007/s00535-006-1951-6, 17287896.
39. Katsuda N, Hamajima N, Tamakoshi A, Wakai K, Matsuo K, Saito T, Tajima K, Tominaga S. Helicobacter pylori seropositivity and the myeloperoxidase G-463A polymorphism in combination with interleukin-1B C-31T in Japanese health checkup examinees. Jpn J Clin Oncol 2003, 33:192-197. 10.1093/jjco/hyg034, 12810834.
40. García-González MA, Lanas A, Savelkoul PHM, Santolaria S, Benito R, Crusius JBA, Peña AS. Association of interleukin 1 gene family polymorphisms with duodenal ulcer disease. Clin Exp Immunol 2003, 134:525-531. 10.1111/j.1365-2249.2003.02325.x, 1808893, 14632761.
41. Sicinschi LA, López-Carrillo L, Camargo MC, Correa P, Sierra RA, Henry RR, Jia C, Zabaleta J, Piazuelo MB, Schneider BG. Gastric cancer risk in a Mexican Population: Role of Helicobacter pylori cagA positive infection and polymorphisms in interleukin-1 and -10 genes. Int J Cancer 2006, 118:649-657. 10.1002/ijc.21364, 16114018.
42. Silva-Zolezzi I, Hidalgo Miranda A, Estrada Gil1 J, Fernández López JC, Uribe Figueroa L, Contreras A, Balam Ortiz E, del Bosque Plata L, Lara C, Velázquez Fernández D, Goya R, Hernández Lemus E, Dávila C, Barrientos E, March S, Jiménez-Sánchez G. Análisis de la diversidad genómica en las poblaciones mestizas mexicanas para desarrollar medicina genómica en México. Proc Natl Acad Sci U S A. 2009, 106(21):8611-8616. 2680428, 19433783.
43. Furuta T, El-Omar EM, Xiao F, Shirai N, Takashima M, Sugimura H. Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology 2002, 123:92-105. 10.1053/gast.2002.34156, 12105837.
44. Hwang IR, Kodama T, Kikuchi S, Sakai K, Peterson LE, Graham DY, Yamaoka Y. Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1β production in Helicobacter pylori infection. Gastroenterology 2002, 123:1793-803. 10.1053/gast.2002.37043, 12454835.
45. Chakravortya M, Datta D, Choudhuryb A, Roychoudhurya S. IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin. Int J Biochem Cell Biol 2009, 41:1502-1510. 10.1016/j.biocel.2008.12.017, 19166966.
46. Zeng ZR, Hu PJ, Hu S, Pang RP, Chen MH, Ng M, Sung JJY. Association of interleukin 1B gene polymorphisms and gastric cancers in high and low prevalence regions in China. Gut 2003, 52:1684-9. 10.1136/gut.52.12.1684, 1773879, 14633943.
47. Takagi A, Deguchi R, Kobayashi K, Miwa T. Cytokine expressions and H. pylori-associated gastric mucosal lesion. Keio J Med 2002, 51(Suppl 2):51-2.