메뉴 건너뛰기




Volumn 401, Issue 4, 2010, Pages 561-567

Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway

Author keywords

Autophagy; FFA; Insulin; JNK; Pancreatic cells

Indexed keywords

FATTY ACID; MITOGEN ACTIVATED PROTEIN KINASE; MOLECULAR MARKER; PALMITIC ACID;

EID: 77958484950     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.101     Document Type: Article
Times cited : (107)

References (19)
  • 1
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: molecular mechanisms and biological functions of autophagy
    • Levine B., Klionsky D.J. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell 2004, 6:463-477.
    • (2004) Dev. Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 3
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 8
    • 0021328919 scopus 로고
    • A morphometric study of the variations in subcellular structures of rat hepatocytes during 24 hours
    • Uchiyama Y., Asari A. A morphometric study of the variations in subcellular structures of rat hepatocytes during 24 hours. Cell Tissue Res. 1984, 236:305-315.
    • (1984) Cell Tissue Res. , vol.236 , pp. 305-315
    • Uchiyama, Y.1    Asari, A.2
  • 11
    • 0033968625 scopus 로고    scopus 로고
    • Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
    • Takeuchi O., Takeda K., Hoshino K., Adachi O., Ogawa T., Akira S. Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int. Immunol. 2000, 12:113-117.
    • (2000) Int. Immunol. , vol.12 , pp. 113-117
    • Takeuchi, O.1    Takeda, K.2    Hoshino, K.3    Adachi, O.4    Ogawa, T.5    Akira, S.6
  • 12
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities
    • Cnop M., Welsh N., Jonas J.C., Jorns A., Lenzen S., Eizirik D.L. Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 2005, 54 (Suppl 2):S97-107.
    • (2005) Diabetes
    • Cnop, M.1    Welsh, N.2    Jonas, J.C.3    Jorns, A.4    Lenzen, S.5    Eizirik, D.L.6
  • 13
    • 75749108288 scopus 로고    scopus 로고
    • Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis
    • Nakamura T., Furuhashi M., Li P., Cao H., Tuncman G., Sonenberg N., Gorgun C.Z., Hotamisligil G.S. Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell 2010, 140:338-348.
    • (2010) Cell , vol.140 , pp. 338-348
    • Nakamura, T.1    Furuhashi, M.2    Li, P.3    Cao, H.4    Tuncman, G.5    Sonenberg, N.6    Gorgun, C.Z.7    Hotamisligil, G.S.8
  • 15
    • 0027418321 scopus 로고
    • The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans
    • Samuel C E The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans. J. Biol. Chem. 1993, 268:7603-7606.
    • (1993) J. Biol. Chem. , vol.268 , pp. 7603-7606
    • Samuel, C.E.1
  • 16
    • 0034663942 scopus 로고    scopus 로고
    • The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin
    • Goh K.C., deVeer M.J., Williams B.R. The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin. EMBO J. 2000, 19:4292-4297.
    • (2000) EMBO J. , vol.19 , pp. 4292-4297
    • Goh, K.C.1    deVeer, M.J.2    Williams, B.R.3
  • 17
    • 33847236171 scopus 로고    scopus 로고
    • Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation
    • Takada Y., Ichikawa H., Pataer A., Swisher S., Aggarwal B.B. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation. Oncogene 2007, 26:1201-1212.
    • (2007) Oncogene , vol.26 , pp. 1201-1212
    • Takada, Y.1    Ichikawa, H.2    Pataer, A.3    Swisher, S.4    Aggarwal, B.B.5
  • 18
    • 68349110789 scopus 로고    scopus 로고
    • JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy
    • Wu H., Wang M.C., Bohmann D. JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy. Mech. Dev. 2009, 126:624-637.
    • (2009) Mech. Dev. , vol.126 , pp. 624-637
    • Wu, H.1    Wang, M.C.2    Bohmann, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.