Inhibition of AΒ42 peptide aggregation by a binuclear ruthenium(II)-Platinum(II) complex: Potential for multimetal organometallics as anti-amyloid agents

ACS Chemical Neuroscience

Volumn 1, Issue 10, 2010, Pages 691-701

  Kumar, Amit ^a   Moody, Lamaryet ^a   Olaivar, Jason F ^a   Lewis, Nerissa A ^a   Khade, Rahul L ^a   Holder, Alvin A ^a   Zhang, Yong ^a,b   Rangachari, Vijayaraghavan ^a  

^a The University of Southern Mississippi   (United States)

^b Stevens Institute of Technology   (United States)

Author keywords

aggregation; Amyloid; and intercalation; cisplatin; inhibitor; organometallics; platinum(II); ruthenium(II)

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; ORGANOMETALLIC COMPOUND; PLATINUM COMPLEX; PROTEIN AGGREGATION INHIBITOR; PROTEIN INHIBITOR; RUTHENIUM COMPLEX; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; DRUG DESIGN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN AGGREGATION INHIBITION; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN MODIFICATION;

EID: 77958449833     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn100046m     Document Type: Article

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