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Volumn 12, Issue 5, 2010, Pages 310-318

Intestinal mesenchymal cells

Author keywords

Adaptive immunity; Alpha smooth muscle actin; Antigen presentation; Cancer microenvironment; Colorectal cancer; Fibrocyte; Inflammation; Inflammatory bowel disease; Innate immunity; Intestinal immunity; Intestinal inflammation; Intestinal morphogenesis; Lymphatic lacteal; Mesenchymal stem cell; Mucosal immunology; Mucosal tolerance; Muscularis mucosae; Myofibroblast; Pericyte; Programmed cell death ligands; Regulatory T cell; Stem cell niche; Stromal cell

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BASIC FIBROBLAST GROWTH FACTOR; BONE MORPHOGENETIC PROTEIN; CYCLOOXYGENASE 2; DESMIN; EOTAXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; RANTES; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; SONIC HEDGEHOG PROTEIN; THY 1 ANTIGEN; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN; WNT PROTEIN; WNT4 PROTEIN; WNT5A PROTEIN; WNT5B PROTEIN;

EID: 77958166490     PISSN: 15228037     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11894-010-0135-y     Document Type: Review
Times cited : (82)

References (51)
  • 1
    • 33947706133 scopus 로고    scopus 로고
    • Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut
    • DOI 10.1016/j.pharmthera.2006.12.004, PII S0163725807000137
    • A Andoh S Bamba M Brittan, et al. 2007 Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut Pharmacol Ther 114 94 106 1:CAS:528:DC%2BD2sXjs1Kqsbg%3D 10.1016/j.pharmthera.2006.12.004 17328956 This comprehensive review of myofibroblast biology covers the cytokine/chemokine networks, cascades, and receptors expressed by intestinal myofibroblast. The focus on IL-22, IL-23, IL-17, and the proinflammatory cyokines as well as secretion of matrix modifying molecules such as the matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) indicate the potential role for these cells in inflamatory bowel disease pathogenesis (Pubitemid 46498158)
    • (2007) Pharmacology and Therapeutics , vol.114 , Issue.1 , pp. 94-106
    • Andoh, A.1    Bamba, S.2    Brittan, M.3    Fujiyama, Y.4    Wright, N.A.5
  • 2
    • 77958188278 scopus 로고    scopus 로고
    • Mesenchymal cells of the intestinal lamina propria
    • in press. This review is an expanded and more detailed version covering many of the issues discussed briefly in this present Current Gastroenterology Reports article
    • Powell DW, Pinchuk IV, Saada JI, et al.: Mesenchymal cells of the intestinal lamina propria. Annu Rev Physiol 2011, in press. This review is an expanded and more detailed version covering many of the issues discussed briefly in this present Current Gastroenterology Reports article.
    • (2011) Annu Rev Physiol
    • Powell, D.W.1    Pinchuk, I.V.2    Saada, J.I.3
  • 3
    • 35448943539 scopus 로고    scopus 로고
    • Subepithelial Fibroblasts in Intestinal Villi: Roles in Intercellular Communication
    • DOI 10.1016/S0074-7696(07)64004-2, PII S0074769607640042, A Survey of Cell Biology
    • S Furuya K Furuya 2007 Subepithelial fibroblasts in intestinal villi: roles in intercellular communication Int Rev Cytol 264 165 223 1:CAS:528:DC%2BD1cXhsVers74%3D 10.1016/S0074-7696(07)64004-2 17964923 This is an outstanding review of the anatomy and biology of intestinal myofibroblasts from an entirely different perspective than the information in this Current Gastroenterology Report. This review by the Furuyas deals with, among other aspects, the mechanosensitive properties of myofibroblasts and how they act as a gap junction and adherens junction-connected network, contracting in response to purinergic and endothelial agonists (Pubitemid 47628852)
    • (2007) International Review of Cytology , vol.264 , pp. 165-223
    • Furuya, S.1    Furuya, K.2
  • 4
    • 0036311203 scopus 로고    scopus 로고
    • Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps
    • 12088453
    • PA Adegboyega RC Mifflin JF DiMari, et al. 2002 Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps Arch Pathol Lab Med 126 829 836 12088453
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 829-836
    • Adegboyega, P.A.1    Mifflin, R.C.2    Dimari, J.F.3
  • 6
    • 34547960749 scopus 로고    scopus 로고
    • The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses
    • DOI 10.1038/labinvest.3700654, PII 3700654
    • A Bellini S Mattoli 2007 The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibrosis Lab Invest 87 858 870 1:CAS:528:DC%2BD2sXptFensbs%3D 10.1038/labinvest.3700654 17607298 (Pubitemid 47267815)
    • (2007) Laboratory Investigation , vol.87 , Issue.9 , pp. 858-870
    • Bellini, A.1    Mattoli, S.2
  • 8
    • 33846685141 scopus 로고    scopus 로고
    • Immmunohistochemical study of the blood and lymphatic vasculature and the innervation of mouse gut and gut-associated lymphoid tissue
    • DOI 10.1111/j.1439-0264.2006.00741.x
    • B Ma R von Wasielewski W Lindenmaier KE Dittmar 2007 Immmunohistochemical study of the blood and lymphatic vasculature and the innervation of mouse gut and gut-associated lymphoid tissue Anat Histol Embryol 36 62 74 1:STN:280:DC%2BD2s%2Fmt1Wjtw%3D%3D 10.1111/j.1439-0264.2006.00741.x 17266671 (Pubitemid 46192825)
    • (2007) Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia , vol.36 , Issue.1 , pp. 62-74
    • Ma, B.1    Von Wasielewski, R.2    Lindenmaier, W.3    Dittmar, K.E.J.4
  • 9
    • 4444299059 scopus 로고    scopus 로고
    • Subepithelial myofibroblasts express cyclooxygenase-2 in colorectal tubular adenomas
    • DOI 10.1158/1078-0432.CCR-0431-03
    • PA Adegboyega O Ololade J Saada, et al. 2004 Subepithelial myofibroblasts express cyclooxygenase-2 in colorectal tubular adenomas Clin Cancer Res 10 5870 5879 1:CAS:528:DC%2BD2cXntlyjtr8%3D 10.1158/1078-0432.CCR-0431-03 15355919 (Pubitemid 39180968)
    • (2004) Clinical Cancer Research , vol.10 , Issue.17 , pp. 5870-5879
    • Adegboyega, P.A.1    Ololade, O.2    Saada, J.3    Mifflin, R.4    Di Mari, J.F.5    Powell, D.W.6
  • 10
    • 13944259054 scopus 로고    scopus 로고
    • Epithelial hedgehog signals pattern the intestinal crypt-villus axis
    • DOI 10.1242/dev.01576
    • BB Madison K Braunstein E Kuizon, et al. 2005 Epithelial hedgehog signals pattern the intestinal crypt-villus axis Development 132 279 289 1:CAS:528:DC%2BD2MXhs1Wgtrk%3D 10.1242/dev.01576 15590741 (Pubitemid 40268278)
    • (2005) Development , vol.132 , Issue.2 , pp. 279-289
    • Madison, B.B.1    Braunstein, K.2    Kuizon, E.3    Portman, K.4    Qiao, X.T.5    Gumucio, D.L.6
  • 11
    • 33745984808 scopus 로고    scopus 로고
    • Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis
    • DOI 10.1096/fj.05-5460rev
    • TA Rege JS Hagood 2006 Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis FASEB J 20 1045 1054 1:CAS:528:DC%2BD28XlvFShtLo%3D 10.1096/fj.05-5460rev 16770003 (Pubitemid 44943900)
    • (2006) FASEB Journal , vol.20 , Issue.8 , pp. 1045-1054
    • Rege, T.A.1    Hagood, J.S.2
  • 12
    • 66149110967 scopus 로고    scopus 로고
    • The role of the visceral mesoderm in the development of the gastrointestinal tract
    • 1:CAS:528:DC%2BD1MXotVeqtLs%3D 10.1053/j.gastro.2009.03.001 19303014
    • VA McLin SJ Henning M Jamrich 2009 The role of the visceral mesoderm in the development of the gastrointestinal tract Gastroenterology 136 2074 2091 1:CAS:528:DC%2BD1MXotVeqtLs%3D 10.1053/j.gastro.2009.03.001 19303014
    • (2009) Gastroenterology , vol.136 , pp. 2074-2091
    • McLin, V.A.1    Henning, S.J.2    Jamrich, M.3
  • 13
    • 10344233141 scopus 로고    scopus 로고
    • Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells
    • DOI 10.1242/dev.01429
    • NM Joseph YS Mukouyama JT Mosher, et al. 2004 Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to schwann cells Development 131 5599 5612 1:CAS:528:DC%2BD2cXhtFSgs7%2FK 10.1242/dev.01429 15496445 (Pubitemid 39625204)
    • (2004) Development , vol.131 , Issue.22 , pp. 5599-5612
    • Joseph, N.M.1    Mukouyama, Y.-S.2    Mosher, J.T.3    Jaegle, M.4    Crone, S.A.5    Dormand, E.-L.6    Lee, K.-F.7    Meijer, D.8    Anderson, D.J.9    Morrison, S.J.10
  • 14
    • 45949085887 scopus 로고    scopus 로고
    • Neural crest origin of perivascular mesenchyme in the adult thymus
    • 18390716
    • SM Muller CC Stolt G Terszowski, et al. 2008 Neural crest origin of perivascular mesenchyme in the adult thymus J Immunol 180 5344 5351 18390716
    • (2008) J Immunol , vol.180 , pp. 5344-5351
    • Muller, S.M.1    Stolt, C.C.2    Terszowski, G.3
  • 15
    • 29644432271 scopus 로고    scopus 로고
    • The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
    • DOI 10.1242/dev.02141
    • B Wilm A Ipenberg ND Hastie, et al. 2005 The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature Development 132 5317 5328 1:CAS:528:DC%2BD28Xktlehuw%3D%3D 10.1242/dev.02141 16284122 (Pubitemid 43020185)
    • (2005) Development , vol.132 , Issue.23 , pp. 5317-5328
    • Wilm, B.1    Ipenberg, A.2    Hastie, N.D.3    Burch, J.B.E.4    Bader, D.M.5
  • 16
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • 1:CAS:528:DC%2BD1MXntVCjtro%3D 10.1172/JCI36183 19487819
    • M Zeisberg EG Neilson 2009 Biomarkers for epithelial-mesenchymal transitions J Clin Invest 119 1429 1437 1:CAS:528:DC%2BD1MXntVCjtro%3D 10.1172/JCI36183 19487819
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 17
    • 73949096744 scopus 로고    scopus 로고
    • Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
    • 1:CAS:528:DC%2BC3cXhs12rtr8%3D 10.2353/ajpath.2010.090517 20008127
    • BD Humphreys S-L Lin A Kobayashi, et al. 2010 Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis Am J Pathol 176 85 97 1:CAS:528:DC%2BC3cXhs12rtr8%3D 10.2353/ajpath.2010.090517 20008127
    • (2010) Am J Pathol , vol.176 , pp. 85-97
    • Humphreys, B.D.1    Lin, S.-L.2    Kobayashi, A.3
  • 18
    • 77950597707 scopus 로고    scopus 로고
    • Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice
    • 10.1002/hep.23368 20052656
    • K Taura K Miura K Iwaisako, et al. 2010 Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice Hepatology 51 1027 1036 10.1002/hep.23368 20052656
    • (2010) Hepatology , vol.51 , pp. 1027-1036
    • Taura, K.1    Miura, K.2    Iwaisako, K.3
  • 19
    • 33846001022 scopus 로고    scopus 로고
    • Wound healing and fibrosis in intestinal disease
    • DOI 10.1136/gut.2006.090456
    • F Rieder J Brenmoehl S Leeb, et al. 2007 Wound healing and fibrosis in intestinal disease Gut 56 130 139 1:CAS:528:DC%2BD2sXhtF2qsbw%3D 10.1136/gut.2006.090456 17172588 (Pubitemid 46044899)
    • (2007) Gut , vol.56 , Issue.1 , pp. 130-139
    • Rieder, F.1    Brenmoehl, J.2    Leeb, S.3    Scholmerich, J.4    Rogler, G.5
  • 20
    • 20444473689 scopus 로고    scopus 로고
    • A regenerative role for bone marrow following experimental colitis: Contribution to neovasculogenesis and myofibroblasts
    • DOI 10.1053/j.gastro.2005.03.028, PII S0016508505004452
    • M Brittan V Chance G Elia, et al. 2005 A regenerative role for bone marrow following experimental colitis: contribution to neovasculogenesis and myofibroblasts Gastroenterology 128 1984 1995 10.1053/j.gastro.2005.03.028 15940631 (Pubitemid 40824707)
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 1984-1995
    • Brittan, M.1    Chance, V.2    Elia, G.3    Poulsom, R.4    Alison, M.R.5    MacDonald, T.T.6    Wright, N.A.7
  • 21
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • 1:CAS:528:DC%2BD1cXhtVamu7vF 10.1038/nri2395 19172693
    • A Uccelli L Moretta V Pistoia 2008 Mesenchymal stem cells in health and disease Nat Rev Immunol 8 726 736 1:CAS:528:DC%2BD1cXhtVamu7vF 10.1038/nri2395 19172693
    • (2008) Nat Rev Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 22
    • 35648977027 scopus 로고    scopus 로고
    • Hedgehog signaling in development and homeostasis of the gastrointestinal tract
    • DOI 10.1152/physrev.00054.2006
    • GR van den Brink 2007 Hedgehog signaling in development and homeostasis of the gastrointestinal tract Physiol Rev 87 1343 1375 10.1152/physrev.00054. 2006 17928586 (Pubitemid 350033824)
    • (2007) Physiological Reviews , vol.87 , Issue.4 , pp. 1343-1375
    • Van Den Brink, G.R.1
  • 23
    • 77952745877 scopus 로고    scopus 로고
    • Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria
    • Zacharias WJ, Li X, Madison BB, et al.: Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria. Gastroenterology 2010
    • (2010) Gastroenterology
    • Zacharias, W.J.1    Li, X.2    Madison, B.B.3
  • 24
    • 77956168783 scopus 로고    scopus 로고
    • Indian hedgehog regulates intestinal stem cell fate through epithelial mesenchymal interactions during development
    • (Epub ahead of print)
    • Kosinski C, Stange DE, Xu C, et al.: Indian hedgehog regulates intestinal stem cell fate through epithelial mesenchymal interactions during development. Gastroenterology 2010 (Epub ahead of print).
    • (2010) Gastroenterology
    • Kosinski, C.1    Stange, D.E.2    Xu, C.3
  • 25
    • 41849085959 scopus 로고    scopus 로고
    • Primary intestinal lymphangiectasia (Waldmann's disease)
    • 10.1186/1750-1172-3-5 18294365
    • S Vignes J Bellanger 2008 Primary intestinal lymphangiectasia (Waldmann's disease) Orphanet J Rare Dis 3 5 10.1186/1750-1172-3-5 18294365
    • (2008) Orphanet J Rare Dis , vol.3 , pp. 5
    • Vignes, S.1    Bellanger, J.2
  • 26
    • 67651159312 scopus 로고    scopus 로고
    • Stem cells, self-renewal, and differentiation in the intestinal epithelium
    • 10.1146/annurev.physiol.010908.163145 18808327 This article provides a thorough review of intestinal stem cell biology and the importance of Wnt signaling. The authors discuss the numerous landmark findings that have recently come from the Clevers laboratory
    • LG van der Flier H Clevers 2009 Stem cells, self-renewal, and differentiation in the intestinal epithelium Annu Rev Physiol 71 241 260 10.1146/annurev.physiol.010908.163145 18808327 This article provides a thorough review of intestinal stem cell biology and the importance of Wnt signaling. The authors discuss the numerous landmark findings that have recently come from the Clevers laboratory
    • (2009) Annu Rev Physiol , vol.71 , pp. 241-260
    • Van Der Flier, L.G.1    Clevers, H.2
  • 27
    • 75649127963 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptors and signal transduction
    • 1:CAS:528:DC%2BC3cXkt1Kmuw%3D%3D 10.1093/jb/mvp148 19762341
    • K Miyazono Y Kamiya M Morikawa 2010 Bone morphogenetic protein receptors and signal transduction J Biochem 147 35 51 1:CAS:528:DC%2BC3cXkt1Kmuw%3D%3D 10.1093/jb/mvp148 19762341
    • (2010) J Biochem , vol.147 , pp. 35-51
    • Miyazono, K.1    Kamiya, Y.2    Morikawa, M.3
  • 29
    • 66149103193 scopus 로고    scopus 로고
    • Depletion of the colonic epithelial precursor cell compartment upon conditional activation of the hedgehog pathway
    • 10.1053/j.gastro.2009.02.068 19272384 e2191-2197
    • WA van Dop A Uhmann M Wijgerde, et al. 2009 Depletion of the colonic epithelial precursor cell compartment upon conditional activation of the hedgehog pathway Gastroenterology 136 2195 2203 10.1053/j.gastro.2009.02.068 19272384 e2191-2197
    • (2009) Gastroenterology , vol.136 , pp. 2195-2203
    • Van Dop, W.A.1    Uhmann, A.2    Wijgerde, M.3
  • 30
    • 77955928161 scopus 로고    scopus 로고
    • Tumors as organs: Complex tissues that interface with the entire organism
    • 1:CAS:528:DC%2BC3cXos1Kqtrk%3D 10.1016/j.devcel.2010.05.012 20627072 This article is a thorough recent review detailing important concepts relating to epithelial-stromal interactions during carcinogenesis
    • M Egeblad ES Nakasone Z Werb 2010 Tumors as organs: complex tissues that interface with the entire organism Developmental Cell 18 884 901 1:CAS:528:DC%2BC3cXos1Kqtrk%3D 10.1016/j.devcel.2010.05.012 20627072 This article is a thorough recent review detailing important concepts relating to epithelial-stromal interactions during carcinogenesis
    • (2010) Developmental Cell , vol.18 , pp. 884-901
    • Egeblad, M.1    Nakasone, E.S.2    Werb, Z.3
  • 31
    • 33646384428 scopus 로고    scopus 로고
    • Fibroblasts in cancer
    • 1:CAS:528:DC%2BD28XjslGitLw%3D 10.1038/nrc1877 16572188
    • R Kalluri M Zeisberg 2006 Fibroblasts in cancer Nat Rev Cancer 6 392 1:CAS:528:DC%2BD28XjslGitLw%3D 10.1038/nrc1877 16572188
    • (2006) Nat Rev Cancer , vol.6 , pp. 392
    • Kalluri, R.1    Zeisberg, M.2
  • 32
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • A Orimo PB Gupta DC Sgroi, et al. 2005 Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCl12 secretion Cell 121 335 348 1:CAS:528:DC%2BD2MXktlSiu7w%3D 10.1016/j.cell.2005.02.034 15882617 (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 34
    • 31544465706 scopus 로고    scopus 로고
    • 2-stimulated intestinal epithelial proliferation and angiogenesis
    • DOI 10.1158/0008-5472.CAN-05-2606
    • J Shao GG Sheng RC Mifflin, et al. 2006 Roles of myofibroblasts in prostaglandin E2-stimulated intestinal epithelial proliferation and angiogenesis Cancer Res 66 846 855 1:CAS:528:DC%2BD28XlsFOrtQ%3D%3D 10.1158/0008-5472.CAN- 05-2606 16424017 (Pubitemid 43165950)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 846-855
    • Shao, J.1    Sheng, G.G.2    Mifflin, R.C.3    Powell, D.W.4    Sheng, H.5
  • 35
    • 52549113913 scopus 로고    scopus 로고
    • Bone morphogenetic protein signalling in colorectal cancer
    • 1:CAS:528:DC%2BD1cXhtFCrtbnO 10.1038/nrc2467 18756288
    • JC Hardwick LL Kodach GJ Offerhaus GR van den Brink 2008 Bone morphogenetic protein signalling in colorectal cancer Nat Rev Cancer 8 806 812 1:CAS:528:DC%2BD1cXhtFCrtbnO 10.1038/nrc2467 18756288
    • (2008) Nat Rev Cancer , vol.8 , pp. 806-812
    • Hardwick, J.C.1    Kodach, L.L.2    Offerhaus, G.J.3    Van Den Brink, G.R.4
  • 36
    • 77951684109 scopus 로고    scopus 로고
    • Aberrant epithelial mesenchymal hedgehog signaling characterizes Barrett's metaplasia
    • 1:CAS:528:DC%2BC3cXmsFyktb8%3D 10.1053/j.gastro.2010.01.048 20138038
    • DH Wang NJ Clemons T Miyashita, et al. 2010 Aberrant epithelial mesenchymal hedgehog signaling characterizes Barrett's metaplasia Gastroenterology 138 1810 1822 1:CAS:528:DC%2BC3cXmsFyktb8%3D 10.1053/j.gastro.2010.01.048 20138038
    • (2010) Gastroenterology , vol.138 , pp. 1810-1822
    • Wang, D.H.1    Clemons, N.J.2    Miyashita, T.3
  • 37
    • 0038281478 scopus 로고    scopus 로고
    • Intestinal myofibroblasts in innate immune responses of the intestine
    • DOI 10.1016/S0016-5085(03)00403-7
    • JM Otte IM Rosenberg DK Podolsky 2003 Intestinal myofibroblasts in innate immune responses of the intestine Gastroenterology 124 1866 1878 1:CAS:528:DC%2BD3sXlt1yrtLY%3D 10.1016/S0016-5085(03)00403-7 12806620 (Pubitemid 36666782)
    • (2003) Gastroenterology , vol.124 , Issue.7 , pp. 1866-1878
    • Otte, J.-M.1    Rosenberg, I.M.2    Podolsky, D.K.3
  • 38
    • 0028175988 scopus 로고
    • GM-CSF, IL-1, IL-1, IL-6, IL-8, IL-10, ICAM-1 and VCAM-1 gene expression and cytokine production in human duodenal fibroblasts stimulated with lipopolysaccharide, IL-1 and TNF
    • 1:CAS:528:DyaK2cXltVKgsrs%3D 10.1111/j.1365-2249.1994.tb06048.x 8004813
    • G Pang L Couch R Batey, et al. 1994 GM-CSF, IL-1, IL-1, IL-6, IL-8, IL-10, ICAM-1 and VCAM-1 gene expression and cytokine production in human duodenal fibroblasts stimulated with lipopolysaccharide, IL-1 and TNF Clin Exp Immunol 96 437 443 1:CAS:528:DyaK2cXltVKgsrs%3D 10.1111/j.1365-2249.1994. tb06048.x 8004813
    • (1994) Clin Exp Immunol , vol.96 , pp. 437-443
    • Pang, G.1    Couch, L.2    Batey, R.3
  • 39
    • 33750344702 scopus 로고    scopus 로고
    • Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa
    • 1:CAS:528:DC%2BD28XhtFSns7zM 17056521
    • JI Saada IV Pinchuk CA Barrera, et al. 2006 Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa J Immunol 177 5968 5979 1:CAS:528:DC%2BD28XhtFSns7zM 17056521
    • (2006) J Immunol , vol.177 , pp. 5968-5979
    • Saada, J.I.1    Pinchuk, I.V.2    Barrera, C.A.3
  • 40
    • 38449121250 scopus 로고    scopus 로고
    • The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells
    • 1:CAS:528:DC%2BD2sXpt1Sms74%3D 17709496 This article is an excellent innovative research report that presents evidence that mature mesenchymal stromal cells play a tolerogenic function in T-cell homeostasis via suppression of the activation/proliferation of T cells. Further, the authors present evidence that this immunosupressive effect is a fundamental characteristic of all mesenchymal stromal cells
    • S Jones N Horwood A Cope F Dazzi 2007 The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells J Immunol 179 2824 2831 1:CAS:528:DC%2BD2sXpt1Sms74%3D 17709496 This article is an excellent innovative research report that presents evidence that mature mesenchymal stromal cells play a tolerogenic function in T-cell homeostasis via suppression of the activation/proliferation of T cells. Further, the authors present evidence that this immunosupressive effect is a fundamental characteristic of all mesenchymal stromal cells
    • (2007) J Immunol , vol.179 , pp. 2824-2831
    • Jones, S.1    Horwood, N.2    Cope, A.3    Dazzi, F.4
  • 41
    • 53049099600 scopus 로고    scopus 로고
    • PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity
    • + T cell responses to acheivew homeostasis. The authors outline mechanisms involved in the cell contact mediated suppression of activated effector T cells
    • + T cell responses to acheivew homeostasis. The authors outline mechanisms involved in the cell contact mediated suppression of activated effector T cells
    • (2008) Gastroenterology , vol.135 , pp. 1228-1237
    • Pinchuk, I.V.1    Saada, J.I.2    Beswick, E.J.3
  • 42
    • 33846005781 scopus 로고    scopus 로고
    • IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin
    • DOI 10.1182/blood-2006-02-002873
    • RA Clark TS Kupper 2007 IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin Blood 109 194 202 1:CAS:528:DC%2BD2sXivVyrtbc%3D 10.1182/blood-2006-02-002873 16968902 (Pubitemid 46053061)
    • (2007) Blood , vol.109 , Issue.1 , pp. 194-202
    • Clark, R.A.1    Kupper, T.S.2
  • 43
    • 40349088832 scopus 로고    scopus 로고
    • Fibroblasts as novel therapeutic targets in chronic inflammation
    • 1:CAS:528:DC%2BD1cXislSjtr8%3D 17965753 This is an innovative review that further develops the concept proposed by Buckley et al. in 2001 suggesting the key role of stromal mesenchymal cells (i.e., fibroblasts) in the switch from acute to chronic inflammation and its application for the development of therapy against chronic inlammatory diseases
    • SJ Flavell TZ Hou S Lax, et al. 2008 Fibroblasts as novel therapeutic targets in chronic inflammation Br J Pharmacol 153 Suppl 1 S241 S246 1:CAS:528:DC%2BD1cXislSjtr8%3D 17965753 This is an innovative review that further develops the concept proposed by Buckley et al. in 2001 suggesting the key role of stromal mesenchymal cells (i.e., fibroblasts) in the switch from acute to chronic inflammation and its application for the development of therapy against chronic inlammatory diseases
    • (2008) Br J Pharmacol , vol.153 , Issue.SUPPL. 1
    • Flavell, S.J.1    Hou, T.Z.2    Lax, S.3
  • 44
    • 34250178699 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 production by intestinal myofibroblasts in response to staphylococcal enterotoxin A: Relevance to staphylococcal enterotoxigenic disease
    • 1:CAS:528:DC%2BD2sXmtVKnsbw%3D 17548648
    • IV Pinchuk EJ Beswick JI Saada, et al. 2007 Monocyte chemoattractant protein-1 production by intestinal myofibroblasts in response to staphylococcal enterotoxin A: relevance to staphylococcal enterotoxigenic disease J Immunol 178 8097 8106 1:CAS:528:DC%2BD2sXmtVKnsbw%3D 17548648
    • (2007) J Immunol , vol.178 , pp. 8097-8106
    • Pinchuk, I.V.1    Beswick, E.J.2    Saada, J.I.3
  • 45
    • 0035081211 scopus 로고    scopus 로고
    • Differential activation of cytokine secretion in primary human colonic fibroblast/myofibroblast cultures
    • 1:CAS:528:DC%2BD3MXjs1Wis7g%3D 10.1080/003655201300051216 11336164
    • G Rogler CM Gelbmann D Vogl, et al. 2001 Differential activation of cytokine secretion in primary human colonic fibroblast/myofibroblast cultures Scand J Gastroenterol 36 389 398 1:CAS:528:DC%2BD3MXjs1Wis7g%3D 10.1080/003655201300051216 11336164
    • (2001) Scand J Gastroenterol , vol.36 , pp. 389-398
    • Rogler, G.1    Gelbmann, C.M.2    Vogl, D.3
  • 46
    • 0034830886 scopus 로고    scopus 로고
    • Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
    • 1:CAS:528:DC%2BD3MXntVKntr4%3D 10.1053/gast.2001.27188 11522753
    • MC Wright R Issa DE Smart, et al. 2001 Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats Gastroenterology 121 685 698 1:CAS:528:DC%2BD3MXntVKntr4%3D 10.1053/gast.2001.27188 11522753
    • (2001) Gastroenterology , vol.121 , pp. 685-698
    • Wright, M.C.1    Issa, R.2    Smart, D.E.3
  • 47
    • 77956246824 scopus 로고    scopus 로고
    • Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis
    • Mei SH, Haitsma JJ, Dos Santos CC, et al.: Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med 2010
    • (2010) Am J Respir Crit Care Med
    • Mei, S.H.1    Haitsma, J.J.2    Dos Santos, C.C.3
  • 48
    • 0034882269 scopus 로고    scopus 로고
    • Altered response of intestinal mucosal fibroblasts to profibrogenic cytokines in inflammatory bowel disease
    • 1:STN:280:DC%2BD3MvntFShtg%3D%3D 10.1097/00054725-200108000-00008 11515849
    • IC Lawrance L Maxwell W Doe 2001 Altered response of intestinal mucosal fibroblasts to profibrogenic cytokines in inflammatory bowel disease Inflamm Bowel Dis 7 226 236 1:STN:280:DC%2BD3MvntFShtg%3D%3D 10.1097/00054725-200108000- 00008 11515849
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 226-236
    • Lawrance, I.C.1    Maxwell, L.2    Doe, W.3
  • 49
    • 70349496209 scopus 로고    scopus 로고
    • Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia: Significant alterations of NCAM+ or alpha-SMA+ subepithelial myofibroblasts and interstitial cells
    • 1:CAS:528:DC%2BD1MXhsVKgtrjO 10.1111/j.1440-1827.2009.02432.x 19788615
    • I Okayasu T Yoshida T Mikami, et al. 2009 Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia: Significant alterations of NCAM+ or alpha-SMA+ subepithelial myofibroblasts and interstitial cells Pathol Int 59 701 711 1:CAS:528:DC%2BD1MXhsVKgtrjO 10.1111/j.1440-1827. 2009.02432.x 19788615
    • (2009) Pathol Int , vol.59 , pp. 701-711
    • Okayasu, I.1    Yoshida, T.2    Mikami, T.3
  • 50
    • 59849091302 scopus 로고    scopus 로고
    • Degeneration of the pericryptal myofibroblast sheath by proinflammatory cytokines in inflammatory bowel diseases
    • 1:CAS:528:DC%2BD1MXht1Cqs7g%3D 10.1053/j.gastro.2008.10.014 18976656
    • C Francoeur Y Bouatrouss A Seltana, et al. 2009 Degeneration of the pericryptal myofibroblast sheath by proinflammatory cytokines in inflammatory bowel diseases Gastroenterology 136 268 277 1:CAS:528:DC%2BD1MXht1Cqs7g%3D 10.1053/j.gastro.2008.10.014 18976656
    • (2009) Gastroenterology , vol.136 , pp. 268-277
    • Francoeur, C.1    Bouatrouss, Y.2    Seltana, A.3
  • 51
    • 0032782848 scopus 로고    scopus 로고
    • Myofibroblasts. I. Paracrine cells important in health and disease
    • 1:CAS:528:DyaK1MXkslKgtLY%3D 10409103
    • DW Powell RC Mifflin JD Valentich, et al. 1999 Myofibroblasts. I. Paracrine cells important in health and disease Am J Physiol 277 C1 C9 1:CAS:528:DyaK1MXkslKgtLY%3D 10409103
    • (1999) Am J Physiol , vol.277
    • Powell, D.W.1    Mifflin, R.C.2    Valentich, J.D.3


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