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Volumn 59, Issue 10, 2009, Pages 701-711

Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia: Significant alterations of NCAM+ or α-SMA+ subepithelial myofibroblasts and interstitial cells: Original Article

Author keywords

Mesenchymal phenotype; Stellate cells; Stromal cells; Subepithelial myofibroblasts; Tumorigenesis and mucosal remodeling; Ulcerative colitis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; NERVE CELL ADHESION MOLECULE;

EID: 70349496209     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2009.02432.x     Document Type: Article
Times cited : (15)

References (50)
  • 1
    • 0019379322 scopus 로고
    • Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis; An indication for colectomy
    • Blackstone MO, Riddell RH, Rogers BH, Levin B. Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis; an indication for colectomy. Gastroenterology 1981 80 : 366 374.
    • (1981) Gastroenterology , vol.80 , pp. 366-374
    • Blackstone, M.O.1    Riddell, R.H.2    Rogers, B.H.3    Levin, B.4
  • 2
    • 0023237958 scopus 로고
    • Colon cancer, dysplasia, and surveillance in patients with ulcerative colitis. A critical review
    • Collins RH Jr., Feldman M, Fordtran JS. Colon cancer, dysplasia, and surveillance in patients with ulcerative colitis. A critical review. N Engl J Med 1987 316 : 1654 1658.
    • (1987) N Engl J Med , vol.316 , pp. 1654-1658
    • Collins, Jr.R.H.1    Feldman, M.2    Fordtran, J.S.3
  • 3
    • 0001712906 scopus 로고
    • Development of colorectal cancer in ulcerative colitis, clinicopathological study of 347 patients and new concepts of cancer development from analysis of mucosal cell proliferation activity
    • with English abstract).
    • Okayasu I, Fujiwara M, Takemura T, Toyoshima H, Nakamura K. Development of colorectal cancer in ulcerative colitis, clinicopathological study of 347 patients and new concepts of cancer development from analysis of mucosal cell proliferation activity. Stomach and Intestine (Tokyo) 1993 28 : 171 179 (with English abstract).
    • (1993) Stomach and Intestine (Tokyo) , vol.28 , pp. 171-179
    • Okayasu, I.1    Fujiwara, M.2    Takemura, T.3    Toyoshima, H.4    Nakamura, K.5
  • 5
    • 85047688990 scopus 로고    scopus 로고
    • Apoptosis regulation differs between ulcerative colitis-associated and sporadic colonic tumors: Association with survivin and bcl-2
    • Mikami T, Yoshida T, Akino F, Motoori T, Yajima M, Okayasu I. Apoptosis regulation differs between ulcerative colitis-associated and sporadic colonic tumors: Association with survivin and bcl-2. Am J Clin Pathol 2003 119 : 723 730.
    • (2003) Am J Clin Pathol , vol.119 , pp. 723-730
    • Mikami, T.1    Yoshida, T.2    Akino, F.3    Motoori, T.4    Yajima, M.5    Okayasu, I.6
  • 6
    • 33644518370 scopus 로고    scopus 로고
    • Disruption of the p53-p53R2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis
    • Yoshida T, Haga S, Numata Y et al. Disruption of the p53-p53R2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis. Int J Cancer 2006 118 : 1395 1403.
    • (2006) Int J Cancer , vol.118 , pp. 1395-1403
    • Yoshida, T.1    Haga, S.2    Numata, Y.3
  • 7
    • 0028122352 scopus 로고
    • Mutations in the p53 gene: An early marker of neoplastic progression in ulcerative colitis
    • Brentnall TA, Crispin DA, Rabinovitch PS et al. Mutations in the p53 gene: An early marker of neoplastic progression in ulcerative colitis. Gastroenterology 1994 107 : 369 378.
    • (1994) Gastroenterology , vol.107 , pp. 369-378
    • Brentnall, T.A.1    Crispin, D.A.2    Rabinovitch, P.S.3
  • 8
    • 0031970280 scopus 로고    scopus 로고
    • Comparative analysis of histology, DNA content, p53 and Ki-ras mutations in colectomy specimens with long-standing ulcerative colitis
    • Holzmann K, Klump B, Borchard F et al. Comparative analysis of histology, DNA content, p53 and Ki-ras mutations in colectomy specimens with long-standing ulcerative colitis. Int J Cancer 1998 76 : 1 6.
    • (1998) Int J Cancer , vol.76 , pp. 1-6
    • Holzmann, K.1    Klump, B.2    Borchard, F.3
  • 9
    • 0346606862 scopus 로고    scopus 로고
    • Increased p53 mutation load in non-cancerous colon tissue from ulcerative colitis: A cancer-prone chronic inflammatory disease
    • Hussain SP, Amstad P, Raja K et al. Increased p53 mutation load in non-cancerous colon tissue from ulcerative colitis: A cancer-prone chronic inflammatory disease. Cancer Res 2000 60 : 3333 3337.
    • (2000) Cancer Res , vol.60 , pp. 3333-3337
    • Hussain, S.P.1    Amstad, P.2    Raja, K.3
  • 10
    • 0037314548 scopus 로고    scopus 로고
    • Diverse p53 alterations in ulcerative colitis-associated low grade dysplasia: Full-length gene sequencing in microdissected single crypts
    • Yoshida T, Mikami T, Mitomi T, Okayasu I. Diverse p53 alterations in ulcerative colitis-associated low grade dysplasia: Full-length gene sequencing in microdissected single crypts. J Pathol 2003 199 : 166 175.
    • (2003) J Pathol , vol.199 , pp. 166-175
    • Yoshida, T.1    Mikami, T.2    Mitomi, T.3    Okayasu, I.4
  • 11
    • 0037089459 scopus 로고    scopus 로고
    • Significant increase of colonic mutated crypts in ulcerative colitis correlatively with duration of illness
    • Okayasu I, Hana K, Yoshida T, Mikami T, Kanno J, Fujiwara M. Significant increase of colonic mutated crypts in ulcerative colitis correlatively with duration of illness. Cancer Res 2002 62 : 2236 2238.
    • (2002) Cancer Res , vol.62 , pp. 2236-2238
    • Okayasu, I.1    Hana, K.2    Yoshida, T.3    Mikami, T.4    Kanno, J.5    Fujiwara, M.6
  • 12
    • 33645543380 scopus 로고    scopus 로고
    • Significant increase of colonic mutated crypts correlates with age in sporadic cancer and diverticulosis cases, with higher frequency in the left- than right-side colorectum
    • Okayasu I, Hana K, Tsuruta T et al. Significant increase of colonic mutated crypts correlates with age in sporadic cancer and diverticulosis cases, with higher frequency in the left- than right-side colorectum. Cancer Sci 2006 97 : 362 367.
    • (2006) Cancer Sci , vol.97 , pp. 362-367
    • Okayasu, I.1    Hana, K.2    Tsuruta, T.3
  • 13
    • 34247891624 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase and hMLH1 in ulcerative colitis-associated tumors
    • 6-methylguanine DNA methyltransferase and hMLH1 in ulcerative colitis-associated tumors. Am J Clin Pathol 2007 127 : 363 373.
    • (2007) Am J Clin Pathol , vol.127 , pp. 363-373
    • Mikami, T.1    Yoshida, T.2    Numata, Y.3
  • 14
    • 5044233455 scopus 로고    scopus 로고
    • INK4A and Bax in p53 wild/p53- overexpressing crypts in ulcerative colitis-associated tumours
    • INK4A and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours. Br J Cancer 2004 91 : 1081 1088.
    • (2004) Br J Cancer , vol.91 , pp. 1081-1088
    • Yoshida, T.1    Matsumoto, N.2    Mikami, T.3    Okayasu, I.4
  • 15
    • 0141885131 scopus 로고    scopus 로고
    • High epithelial and stromal genetic instability of chromosome 17 in ulcerative colitis-associated carcinogenesis
    • Matsumoto N, Yoshida T, Okayasu I. High epithelial and stromal genetic instability of chromosome 17 in ulcerative colitis-associated carcinogenesis. Cancer Res 2003 63 : 6158 6161.
    • (2003) Cancer Res , vol.63 , pp. 6158-6161
    • Matsumoto, N.1    Yoshida, T.2    Okayasu, I.3
  • 16
    • 0043236148 scopus 로고    scopus 로고
    • Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma
    • Matsumoto N, Yoshida T, Yamashita K, Numata Y, Okayasu I. Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma. Br J Cancer 2003 89 : 707 712.
    • (2003) Br J Cancer , vol.89 , pp. 707-712
    • Matsumoto, N.1    Yoshida, T.2    Yamashita, K.3    Numata, Y.4    Okayasu, I.5
  • 17
    • 33646249638 scopus 로고    scopus 로고
    • Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas
    • Ishiguro K, Yoshida T, Yagishita H, Numata Y, Okayasu I. Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas. Gut 2006 55 : 695 702.
    • (2006) Gut , vol.55 , pp. 695-702
    • Ishiguro, K.1    Yoshida, T.2    Yagishita, H.3    Numata, Y.4    Okayasu, I.5
  • 18
    • 42149189528 scopus 로고    scopus 로고
    • Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis
    • Yagishita H, Yoshida T, Ishiguro K, Numata Y, Okayasu I. Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis. Scand J Gastroenterol 2008 43 : 559 566.
    • (2008) Scand J Gastroenterol , vol.43 , pp. 559-566
    • Yagishita, H.1    Yoshida, T.2    Ishiguro, K.3    Numata, Y.4    Okayasu, I.5
  • 20
    • 0031408125 scopus 로고    scopus 로고
    • Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2
    • Mahida YR, Beltinger J, Makh S et al. Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am J Physiol Gastrointest Liver Physiol 1997 273 : 1341 1348.
    • (1997) Am J Physiol Gastrointest Liver Physiol , vol.273 , pp. 1341-1348
    • Mahida, Y.R.1    Beltinger, J.2    Makh, S.3
  • 21
    • 0019230284 scopus 로고
    • Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs
    • Wake K. Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs. Int Rev Cytol 1980 66 : 303 353.
    • (1980) Int Rev Cytol , vol.66 , pp. 303-353
    • Wake, K.1
  • 22
    • 0026505418 scopus 로고
    • Direct mobilization of retinol from hepatic perisinusoidal stellate cells to plasma
    • Andersen KB, Nilsson A, Blomhoff HK et al. Direct mobilization of retinol from hepatic perisinusoidal stellate cells to plasma. J Biol Chem 1992 267 : 1340 1344.
    • (1992) J Biol Chem , vol.267 , pp. 1340-1344
    • Andersen, K.B.1    Nilsson, A.2    Blomhoff, H.K.3
  • 23
    • 33947235684 scopus 로고    scopus 로고
    • The diffuse stellate cell system
    • Zhao L, Burt AD. The diffuse stellate cell system. J Mol Histol 2007 38 : 53 64.
    • (2007) J Mol Histol , vol.38 , pp. 53-64
    • Zhao, L.1    Burt, A.D.2
  • 24
    • 33845567511 scopus 로고    scopus 로고
    • Activated perilobular, not periacinar, pancreatic stellate cells contribute to fibrogenesis in chronic alcoholic pancreatitis
    • Suda K, Fukushima Y, Takase M et al. Activated perilobular, not periacinar, pancreatic stellate cells contribute to fibrogenesis in chronic alcoholic pancreatitis. Pathol Int 2007 57 : 21 5.
    • (2007) Pathol Int , vol.57 , pp. 21-5
    • Suda, K.1    Fukushima, Y.2    Takase, M.3
  • 25
    • 0021017589 scopus 로고
    • Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications
    • Riddell RH, Goldman H, Ransohoff DF et al. Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications. Hum Pathol 1983 14 : 931 968.
    • (1983) Hum Pathol , vol.14 , pp. 931-968
    • Riddell, R.H.1    Goldman, H.2    Ransohoff, D.F.3
  • 27
    • 0029047515 scopus 로고
    • Evaluation of disease activity in patients with moderately active ulcerative colitis: Comparison between a new activity index and Truelove and Witts' classification
    • Seo M, Okada M, Yao T, Okabe N, Maeda K, Oh K. Evaluation of disease activity in patients with moderately active ulcerative colitis: Comparison between a new activity index and Truelove and Witts' classification. Am J Gastroenterol 1995 90 : 1759 1763.
    • (1995) Am J Gastroenterol , vol.90 , pp. 1759-1763
    • Seo, M.1    Okada, M.2    Yao, T.3    Okabe, N.4    Maeda, K.5    Oh, K.6
  • 28
    • 0030037160 scopus 로고    scopus 로고
    • Localization of human placental glucose transporter 1 during pregnancy. An immunohistochemical study
    • Tadokoro C, Yoshimoto Y, Sakata M et al. Localization of human placental glucose transporter 1 during pregnancy. An immunohistochemical study. Histol Histopathol 1996 11 : 673 681.
    • (1996) Histol Histopathol , vol.11 , pp. 673-681
    • Tadokoro, C.1    Yoshimoto, Y.2    Sakata, M.3
  • 29
    • 0032440684 scopus 로고    scopus 로고
    • Laminin 5 can promote assembly of the lamina densa in the skin equivalent model
    • Tsunenaga M, Adachi E, Amano S, Burgeson RE, Nishiyama T. Laminin 5 can promote assembly of the lamina densa in the skin equivalent model. Matrix Biol 1998 17 : 603 613.
    • (1998) Matrix Biol , vol.17 , pp. 603-613
    • Tsunenaga, M.1    Adachi, E.2    Amano, S.3    Burgeson, R.E.4    Nishiyama, T.5
  • 31
    • 44349126693 scopus 로고    scopus 로고
    • Colonic crypt organization and tumorigenesis
    • Humphries A, Wright NA. Colonic crypt organization and tumorigenesis. Nat Rev Cancer 2008 8 : 415 424.
    • (2008) Nat Rev Cancer , vol.8 , pp. 415-424
    • Humphries, A.1    Wright, N.A.2
  • 32
    • 0028245546 scopus 로고
    • Immunohistochemical identification of Ito cells and their myofibroblastic transformation in adult human liver
    • Enzan H, Himeno H, Iwamura S et al. Immunohistochemical identification of Ito cells and their myofibroblastic transformation in adult human liver. Virchows Arch 1994 424 : 249 256.
    • (1994) Virchows Arch , vol.424 , pp. 249-256
    • Enzan, H.1    Himeno, H.2    Iwamura, S.3
  • 33
    • 0023223073 scopus 로고
    • Characterization of desmin-positive rat liver sinusoidal cells
    • Tsutsumi M, Takada A, Takase S. Characterization of desmin-positive rat liver sinusoidal cells. Hepatology 1987 7 : 277 284.
    • (1987) Hepatology , vol.7 , pp. 277-284
    • Tsutsumi, M.1    Takada, A.2    Takase, S.3
  • 34
    • 0025696005 scopus 로고
    • Expression of the gene of the alpha-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells
    • Ramadori G, Veit T, Schwogler S et al. Expression of the gene of the alpha-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells. Virchows Arch B Cell Pathol Incl Mol Pathol 1990 59 : 349 357.
    • (1990) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.59 , pp. 349-357
    • Ramadori, G.1    Veit, T.2    Schwogler, S.3
  • 35
    • 0030056244 scopus 로고    scopus 로고
    • Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver; Up-regulation during in vitro activation and in hepatic tissue repair
    • Knittel T, Aurisch S, Neubauer K, Eichhorst S, Ramadori G. Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver; up-regulation during in vitro activation and in hepatic tissue repair. Am J Pathol 1996 149 : 449 462.
    • (1996) Am J Pathol , vol.149 , pp. 449-462
    • Knittel, T.1    Aurisch, S.2    Neubauer, K.3    Eichhorst, S.4    Ramadori, G.5
  • 36
    • 0035200716 scopus 로고    scopus 로고
    • Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors
    • DOI 10.1053/jhep.2001.20793
    • Cassiman D, Denef C, Desmet VJ, Roskams T. Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors. Hepatology 2001 33 : 148 158. (Pubitemid 32016897)
    • (2001) Hepatology , vol.33 , Issue.1 , pp. 148-158
    • Cassiman, D.1    Denef, C.2    Desmet, V.J.3    Roskams, T.4
  • 37
    • 0036311203 scopus 로고    scopus 로고
    • Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps
    • Adegboyega PA, Mifflin RC, DiMari JF, Saada JI, Powell DW. Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps. Arch Pathol Lab Med 2002 126 : 829 836.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 829-836
    • Adegboyega, P.A.1    Mifflin, R.C.2    Dimari, J.F.3    Saada, J.I.4    Powell, D.W.5
  • 38
    • 41349106964 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of smad3 with galectin-7
    • Inagaki Y, Higashi K, Kushida M et al. Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of smad3 with galectin-7. Gastroenterology 2008 134 : 1180 1190.
    • (2008) Gastroenterology , vol.134 , pp. 1180-1190
    • Inagaki, Y.1    Higashi, K.2    Kushida, M.3
  • 39
    • 0036100750 scopus 로고    scopus 로고
    • Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon
    • Brittan M, Hunt T, Jeffery R et al. Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon. Gut 2002 50 : 752 757.
    • (2002) Gut , vol.50 , pp. 752-757
    • Brittan, M.1    Hunt, T.2    Jeffery, R.3
  • 40
    • 0041441245 scopus 로고    scopus 로고
    • Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction
    • Ishii G, Sangai T, Oda T et al. Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction. Biochem Biophys Res Commun 2003 309 : 232 240.
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 232-240
    • Ishii, G.1    Sangai, T.2    Oda, T.3
  • 41
    • 0027238642 scopus 로고
    • Significance of pericryptal fibroblasts in colorectal epithelial tumours: A special reference to the histological features and growth patterns
    • Yao T, Tsuneyoshi M. Significance of pericryptal fibroblasts in colorectal epithelial tumours: A special reference to the histological features and growth patterns. Hum Pathol 1993 24 : 525 533.
    • (1993) Hum Pathol , vol.24 , pp. 525-533
    • Yao, T.1    Tsuneyoshi, M.2
  • 42
    • 9244223595 scopus 로고    scopus 로고
    • The demonstration of pericryptal fibroblasts in background mucosa and dysplasia complicating ulcerative colitis
    • Yao T, Talbot IC. The demonstration of pericryptal fibroblasts in background mucosa and dysplasia complicating ulcerative colitis. Histopathology 1996 28 : 325 331.
    • (1996) Histopathology , vol.28 , pp. 325-331
    • Yao, T.1    Talbot, I.C.2
  • 43
    • 68149168040 scopus 로고    scopus 로고
    • High expression of HSP47 in ulcerative colitis-associated carcinomas: Proteomic approach
    • Araki K, Mikami T, Yoshida T et al. High expression of HSP47 in ulcerative colitis-associated carcinomas: Proteomic approach. Br J Cancer 2009 101 : 492 497.
    • (2009) Br J Cancer , vol.101 , pp. 492-497
    • Araki, K.1    Mikami, T.2    Yoshida, T.3
  • 44
    • 60849094060 scopus 로고    scopus 로고
    • Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interaction with myofibroblasts
    • Samuel S, Walsh R, Webb J, Robins A, Potten C, Mahida YR. Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interaction with myofibroblasts. Am J Physiol Cell Physiol 2009 296 : 296 305.
    • (2009) Am J Physiol Cell Physiol , vol.296 , pp. 296-305
    • Samuel, S.1    Walsh, R.2    Webb, J.3    Robins, A.4    Potten, C.5    Mahida, Y.R.6
  • 45
    • 0842288323 scopus 로고    scopus 로고
    • TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick NA, Chytil A, Plieth D et al. TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004 303 : 848 851.
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1    Chytil, A.2    Plieth, D.3
  • 46
    • 33745578957 scopus 로고    scopus 로고
    • Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
    • Kim B-G, Li C, Qiao W et al. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Nature 2006 441 : 1015 1019.
    • (2006) Nature , vol.441 , pp. 1015-1019
    • Kim, B.-G.1    Li, C.2    Qiao, W.3
  • 47
    • 51349152152 scopus 로고    scopus 로고
    • Divergent transforming growth factor-β signaling in hepatic stellate cells after injury
    • Khimji A-K, Shao R, Rockey DC. Divergent transforming growth factor-β signaling in hepatic stellate cells after injury. Am J Pathol 2008 173 : 716 727.
    • (2008) Am J Pathol , vol.173 , pp. 716-727
    • Khimji, A.-K.1    Shao, R.2    Rockey, D.C.3
  • 48
    • 47049116663 scopus 로고    scopus 로고
    • Activated macrophages promote Wnt signaling through tumour necrosis factor-α in gastric tumour cells
    • Oguma K, Oshima H, Aoki M et al. Activated macrophages promote Wnt signaling through tumour necrosis factor-α in gastric tumour cells. EMBO J 2008 27 : 1671 1681.
    • (2008) EMBO J , vol.27 , pp. 1671-1681
    • Oguma, K.1    Oshima, H.2    Aoki, M.3
  • 49
    • 47249162068 scopus 로고    scopus 로고
    • Periostin is expressed in pericryptal fibroblasts and cancer-associated fibroblasts in the colon
    • Kikuchi Y, Kashima TG, Nishiyama T et al. Periostin is expressed in pericryptal fibroblasts and cancer-associated fibroblasts in the colon. J Histochem 2008 56 : 753 764.
    • (2008) J Histochem , vol.56 , pp. 753-764
    • Kikuchi, Y.1    Kashima, T.G.2    Nishiyama, T.3
  • 50
    • 39549107343 scopus 로고    scopus 로고
    • Periostin is essential for cardiac healing after acute myocardial infarction
    • Shimazaki M, Nakamura K, Kii I et al. Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med 2008 205 : 295 303.
    • (2008) J Exp Med , vol.205 , pp. 295-303
    • Shimazaki, M.1    Nakamura, K.2    Kii, I.3


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