Screening of protein kinase inhibitors identifies PKC inhibitors as inhibitors of osteoclastic acid secretion and bone resorption

BMC Musculoskeletal Disorders

Volumn 11, Issue , 2010, Pages

  Sørensen, Mette G ^a   Karsdal, Morten A ^a   Dziegiel, Morten H ^b   Boutin, Jean A ^c   Nosjean, Olivier ^c   Henriksen, Kim ^a  

^a NORDIC BIOSCIENCE A S   (Denmark)

^b Mental Health Services CPH   (Denmark)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ACRIDINE ORANGE; CALCIUM; CD14 ANTIGEN; HYPERICIN; PALMITOYLCARNITINE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; ROTTLERIN; SPHINGOSINE; ACID; PROTEIN KINASE INHIBITOR;

ACID SECRETION; ACIDIFICATION; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYSOSOME; MICROSOME; MONOCYTE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING; ANIMAL; CATTLE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SECRETION;

ACIDS; ANIMALS; BONE RESORPTION; CATTLE; CELLS, CULTURED; HUMANS; OSTEOCLASTS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS;

EID: 77958124067     PISSN: None     EISSN: 14712474     Source Type: Journal    
DOI: 10.1186/1471-2474-11-250     Document Type: Article

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