Examination of Michael addition reactivity towards glutathione by transition-state calculations

SAR and QSAR in Environmental Research

Volumn 21, Issue 7, 2010, Pages 693-710

  Schwobel J A H ^a   Madden, J C ^a   Cronin, M T D ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Glutathione; Kinetics; Michael addition; Peptide adduct formation; Quantum chemistry; Solvent effect; Steric accessibility; Transition state

Indexed keywords

ADDITION REACTIONS; CHEMICAL BONDS; KETONES; PEPTIDES; QUANTUM THEORY; RATE CONSTANTS; SOLVENTS;

ADDUCT FORMATION; GLUTHATHIONE; KINETIC RATE CONSTANTS; MICHAEL ACCEPTORS; MICHAEL ADDITIONS; PEPTIDE ADDUCT FORMATION; RATE CONSTANT K; SOLVENT EFFECTS; STERIC ACCESSIBILITY; TRANSITION STATE;

QUANTUM CHEMISTRY;

EID: 77958086570     PISSN: 1062936X     EISSN: 1029046X     Source Type: Journal    
DOI: 10.1080/1062936X.2010.528943     Document Type: Article

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