Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitor

Journal of Biochemistry

Volumn 148, Issue 4, 2010, Pages 467-479

  Navaneetham, Duraiswamy ^a   Sinha, Dipali ^a   Walsh, Peter N ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BPTI; FXIa; inhibition mechanism; protease nexin 2 Kunitz domain; trypsin

Indexed keywords

ARGININE; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 11A; BLOOD CLOTTING FACTOR 12A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9A; KALLIKREIN; LYSINE; PLASMIN; PROTEASE NEXIN; PROTEASE NEXIN 2; THROMBIN; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; ENZYME ACTIVITY; HUMAN; MUTATION; PROTEIN EXPRESSION; WILD TYPE;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APROTININ; FACTOR XIA; FIBRINOLYSIN; HUMANS; KALLIKREINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; TRYPSIN; TRYPSIN INHIBITORS;

EID: 77958070559     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq080     Document Type: Article

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