Berberine derivatives, with substituted amino groups linked at the 9-position, as inhibitors of acetylcholinesterase/butyrylcholinesterase

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6649-6652

  Huang, Ling ^a   Luo, Zonghua ^a   He, Feng ^a   Shi, Anding ^a   Qin, Fangfei ^a   Li, Xingshu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Acetylcholinesterase; Berberine derivatives; Butyrylcholinesterase; Dual inhibitors; Molecular modeling

Indexed keywords

BERBERINE DERIVATIVE; CHOLINESTERASE INHIBITOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; ENZYME ACTIVITY; MOLECULAR MODEL; STEADY STATE;

ACETYLCHOLINESTERASE; BERBERINE; BUTYRYLCHOLINESTERASE; CATALYTIC DOMAIN; CHOLINESTERASE INHIBITORS; MODELS, MOLECULAR;

EID: 77958070100     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.013     Document Type: Article

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