Screening chemicals for thyroid-disrupting activity: A critical comparison of mammalian and amphibian models

Critical Reviews in Toxicology

Volumn 40, Issue 10, 2010, Pages 845-892

  Pickford, Daniel B ^a  

^a BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

Chemical safety assessment; endocrine disrupter; goitrogen; rodent; Xenopus

Indexed keywords

2 IMIDAZOLIDINETHIONE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 4,4' ISOPROPYLIDENEDIPHENOL; ALACHLOR; ATRAZINE; CAMPHECLOR; DIOXIN; ESTROGEN; FLAME RETARDANT; GLUCOCORTICOID; IODIDE; IODOTHYRONINE; IOPANOIC ACID; MANCOZEB; METHOXYCHLOR; ORGANOCHLORINE PESTICIDE; PERCHLORATE; PHENOBARBITAL; POLYBROMINATED DIPHENYL ETHER; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; PROPYLTHIOURACIL; SULFADIMETHOXINE; TETRABROMOBISPHENOL A; THIAMAZOLE; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID PEROXIDASE; THYROXINE; ZINEB;

AMPHIBIA; DEIODINATION; EXPOSURE; FALSE NEGATIVE RESULT; GOVERNMENT; HISTOPATHOLOGIC SKIN REACTION; HUMAN; HYPOTHYROIDISM; IN VIVO STUDY; LIVER MICROSOME; MAMMAL; METAMORPHOSIS; NONHUMAN; PEER REVIEW; PUBERTY; REVIEW; RISK ASSESSMENT; SCREENING; SENSITIVITY AND SPECIFICITY; SILURANA TROPICALIS; SPECIES COMPARISON; STEROIDOGENESIS; THYROID DISEASE; THYROID HORMONE METABOLISM; THYROID HORMONE SYNTHESIS; THYROXINE BLOOD LEVEL; TOXICITY TESTING; XENOPUS LAEVIS;

AMPHIBIANS; ANIMALS; BIOLOGICAL ASSAY; ENDOCRINE DISRUPTORS; FEMALE; HUMANS; MALE; MAMMALS; METAMORPHOSIS, BIOLOGICAL; MODELS, ANIMAL; RISK ASSESSMENT; THYROID GLAND; THYROID HORMONES; TOXICITY TESTS; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

AMPHIBIA; ANIMALIA; MAMMALIA; RODENTIA; VERTEBRATA;

EID: 77958017547     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408444.2010.494250     Document Type: Review

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