Evaluation of ammonium perchlorate in the endocrine disruptor screening and testing program's male pubertal protocol: Ability to detect effects on thyroid endpoints

Toxicology

Volumn 228, Issue 1, 2006, Pages 58-65

  Stoker, T E ^a   Ferrell, J M ^a   Laws, S C ^a   Cooper, R L ^a   Buckalew, A ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Ammonium perchlorate; Pubertal male assay; Thyroid histology; Thyroid hormone

Indexed keywords

AMMONIUM PERCHLORATE; ENDOCRINE DISRUPTOR; FERTILIZER; FUEL; IODIDE; LIOTHYRONINE; LUBRICATING AGENT; PAINT; POTASSIUM PERCHLORATE; THYROTROPIN; THYROXINE; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLOID; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENITAL SYSTEM; HISTOLOGY; HYPERTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; MALE; MALE GENITAL SYSTEM; NEWBORN; NONHUMAN; ORGANOGENESIS; PILOT STUDY; PREPUTIAL GLAND; PRIORITY JOURNAL; PUBERTY; RAT; SCREENING; THYROID FOLLICLE CELL; THYROID FUNCTION; THYROID GLAND; THYROID HORMONE RELEASE; THYROID HORMONE SYNTHESIS; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

ADMINISTRATION, ORAL; ANIMALS; ANIMALS, NEWBORN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; MALE; ORGAN SIZE; PENIS; PERCHLORIC ACID; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; SEXUAL MATURATION; THYROID GLAND; THYROID HORMONES; TOXICITY TESTS; WATER POLLUTANTS, CHEMICAL; WATER SUPPLY;

RATTUS NORVEGICUS;

EID: 33749992853     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.08.026     Document Type: Article

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