Description and initial evaluation of a Xenopus metamorphosis assay for detection of thyroid system-disrupting activities of environmental compounds

Environmental Toxicology and Chemistry

Volumn 24, Issue 3, 2005, Pages 653-664

  Opitz, Robert ^a   Braunbeck, Thomas ^b   Bögi, Christian ^c   Pickford, Daniel B ^d   Nentwig, Gerrit ^e   Oehlmann, Jörg ^e   Tooi, Osamu ^f   Lutz, Ilka ^a   Kloas, Werner ^a  

^a LEIBNIZ INSTITUTE OF FRESHWATER ECOLOGY AND INLAND FISHERIES   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c BASF SE   (Germany)

^d ASTRAZENECA   (United Kingdom)

^e GOETHE UNIVERSITY   (Germany)

^f Humboldt University Berlin ^*

Author keywords

Endocrine disruption; Metamorphosis; Ring test study; Thyroid system; Xenopus

Indexed keywords

ACCREDITATION; BIODIVERSITY; PHYSIOLOGICAL MODELS; RESEARCH LABORATORIES; TOXICITY;

BIOLOGICAL MODELS; METAMORPHOSIS; TEST PROTOCOLS; THYROID SYSTEMS;

BIOASSAY;

2 IMIDAZOLIDINETHIONE; PROPYLTHIOURACIL; THYROXINE;

BIOASSAY; METAMORPHOSIS;

ARTICLE; BIOASSAY; BIOLOGICAL MODEL; BODY HEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ECOTOXICOLOGY; ENVIRONMENTAL EXPOSURE; EVALUATION; GROWTH RATE; GROWTH RETARDATION; MEASUREMENT; METAMORPHOSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; RELIABILITY; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE; TADPOLE; TECHNIQUE; THYROID DISEASE; TOXICITY TESTING; XENOPUS LAEVIS;

ANIMALS; BIOLOGICAL ASSAY; BODY SIZE; ENVIRONMENTAL POLLUTANTS; ETHYLENETHIOUREA; LARVA; METAMORPHOSIS, BIOLOGICAL; PROPYLTHIOURACIL; THYROID GLAND; THYROXINE; XENOPUS LAEVIS;

AMPHIBIA; ANIMALIA; XEMA; XENOPUS LAEVIS;

EID: 13944272596     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/04-214R.1     Document Type: Article

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