A rat neurodevelopmental evaluation of offspring, including evaluation of adult and neonatal thyroid, from mothers treated with ammonium perchlorate in drinking water

International Journal of Toxicology

Volumn 23, Issue 3, 2004, Pages 191-214

  York, Raymond G ^a   Barnett Jr , John ^a   Brown, W Ray ^b   Garman, Robert H ^c   Mattie, David R ^d   Dodd, Darol ^e  

^a CHARLES RIVER LABORATORIES   (United States)

^b Research Pathology Services   (United States)

^c Consultants in Veterinary Pathology Inc ^*  (United States)

^d AIR FORCE RESEARCH LABORATORY   (United States)

^e ALION SCIENCE AND TECHNOLOGY   (United States)

Author keywords

Developmental Neurotoxicity; Maternal Hypothyroidism; Perchlorate; Rat; Thyroid

Indexed keywords

AMMONIA; DRINKING WATER; LIOTHYRONINE; PERCHLORATE; THYROTROPIN; THYROXINE; AMMONIUM PERCHLORATE; PERCHLORIC ACID; QUATERNARY AMMONIUM DERIVATIVE; THYROID HORMONE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; BRAIN WEIGHT; CONTROLLED STUDY; CORPUS CALLOSUM; FEMALE; FOOD INTAKE; GESTATION PERIOD; GOITER; HYPOTHYROIDISM; LACTATION; MORPHOMETRICS; MOTOR ACTIVITY; NERVE CELL DIFFERENTIATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PASSIVE AVOIDANCE; PRENATAL DRUG EXPOSURE; PROGENY; RAT; SEXUAL MATURATION; SWIMMING; THYROID HYPERPLASIA; ANIMAL; ANIMAL BEHAVIOR; AVOIDANCE BEHAVIOR; BLOOD; BRAIN; DRUG EFFECT; DRUG SURVEILLANCE PROGRAM; GROWTH, DEVELOPMENT AND AGING; MALE; MAZE TEST; NEWBORN; ORAL DRUG ADMINISTRATION; ORGAN SIZE; PATHOLOGY; PREGNANCY; PRENATAL EXPOSURE; SPRAGUE DAWLEY RAT; STARTLE REFLEX; THYROID GLAND; WATER POLLUTANT;

ANIMALIA;

ADMINISTRATION, ORAL; ANIMALS; ANIMALS, NEWBORN; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BRAIN; FEMALE; MALE; MAZE LEARNING; MOTOR ACTIVITY; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PERCHLORIC ACID; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; STARTLE REACTION; THYROID GLAND; THYROID HORMONES; WATER POLLUTANTS, CHEMICAL;

EID: 16544364075     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1080/10915810490475835     Document Type: Article

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