-
2
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell 81 (1995) 323-330
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
3
-
-
0033564697
-
CDK inhibitors: positive and negative regulators of G1-phase progression
-
Sherr C.J., and Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13 (1999) 1501-1512
-
(1999)
Genes Dev.
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
4
-
-
0024473604
-
G1 events and regulation of cell proliferation
-
Pardee A.B. G1 events and regulation of cell proliferation. Science 246 (1989) 603-608
-
(1989)
Science
, vol.246
, pp. 603-608
-
-
Pardee, A.B.1
-
5
-
-
0742282005
-
Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice
-
Wolff L., et al. Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice. Oncogene 22 (2003) 9265-9274
-
(2003)
Oncogene
, vol.22
, pp. 9265-9274
-
-
Wolff, L.1
-
6
-
-
27144458683
-
Cyclins and CDKS in development and cancer: lessons from genetically modified mice
-
Santamaria D., and Ortega S. Cyclins and CDKS in development and cancer: lessons from genetically modified mice. Front. Biosci. 11 (2006) 1164-1188
-
(2006)
Front. Biosci.
, vol.11
, pp. 1164-1188
-
-
Santamaria, D.1
Ortega, S.2
-
7
-
-
0031860559
-
Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells
-
Drexler H.G. Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells. Leukemia 12 (1998) 845-859
-
(1998)
Leukemia
, vol.12
, pp. 845-859
-
-
Drexler, H.G.1
-
8
-
-
0034654269
-
Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications
-
Wong I.H., Ng M.H., Huang D.P., and Lee J.C. Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications. Blood 95 (2000) 1942-1949
-
(2000)
Blood
, vol.95
, pp. 1942-1949
-
-
Wong, I.H.1
Ng, M.H.2
Huang, D.P.3
Lee, J.C.4
-
9
-
-
0038189509
-
Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis
-
Teofili L., et al. Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis. Leukemia 17 (2003) 919-924
-
(2003)
Leukemia
, vol.17
, pp. 919-924
-
-
Teofili, L.1
-
10
-
-
18044374452
-
Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia
-
Shimamoto T., Ohyashiki J.H., and Ohyashiki K. Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia. Leuk. Res. 29 (2005) 653-659
-
(2005)
Leuk. Res.
, vol.29
, pp. 653-659
-
-
Shimamoto, T.1
Ohyashiki, J.H.2
Ohyashiki, K.3
-
11
-
-
0030046322
-
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B
-
Herman J.G., Jen J., Merlo A., and Baylin S.B. Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Res. 56 (1996) 722-727
-
(1996)
Cancer Res.
, vol.56
, pp. 722-727
-
-
Herman, J.G.1
Jen, J.2
Merlo, A.3
Baylin, S.B.4
-
12
-
-
0033991683
-
Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia
-
Guo S.X., et al. Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia. Leuk. Res. 24 (2000) 39-46
-
(2000)
Leuk. Res.
, vol.24
, pp. 39-46
-
-
Guo, S.X.1
-
13
-
-
0033215453
-
p15INK4B CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing
-
Cameron E.E., Baylin S.B., and Herman J.G. p15INK4B CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing. Blood 94 (1999) 2445-2451
-
(1999)
Blood
, vol.94
, pp. 2445-2451
-
-
Cameron, E.E.1
Baylin, S.B.2
Herman, J.G.3
-
14
-
-
33644878393
-
Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients
-
Aggerholm A., Holm M.S., Guldberg P., Olesen L.H., and Hokland P. Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients. Eur. J. Haematol. 76 (2006) 23-32
-
(2006)
Eur. J. Haematol.
, vol.76
, pp. 23-32
-
-
Aggerholm, A.1
Holm, M.S.2
Guldberg, P.3
Olesen, L.H.4
Hokland, P.5
-
15
-
-
33847082188
-
DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia
-
Agrawal S., et al. DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia. Cancer Res. 67 (2007) 1370-1377
-
(2007)
Cancer Res.
, vol.67
, pp. 1370-1377
-
-
Agrawal, S.1
-
16
-
-
0030612423
-
Hypermethylation of the p15INK4B gene in myelodysplastic syndromes
-
Uchida T., et al. Hypermethylation of the p15INK4B gene in myelodysplastic syndromes. Blood 90 (1997) 1403-1409
-
(1997)
Blood
, vol.90
, pp. 1403-1409
-
-
Uchida, T.1
-
17
-
-
0035134705
-
Methylation of the p15(INK4B) gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation
-
Tien H.F., et al. Methylation of the p15(INK4B) gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation. Br. J. Haematol. 112 (2001) 148-154
-
(2001)
Br. J. Haematol.
, vol.112
, pp. 148-154
-
-
Tien, H.F.1
-
18
-
-
0035880261
-
Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors
-
Teofili L., et al. Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors. Blood 98 (2001) 495-497
-
(2001)
Blood
, vol.98
, pp. 495-497
-
-
Teofili, L.1
-
19
-
-
0032523011
-
Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression
-
Quesnel B., et al. Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression. Blood 91 (1998) 2985-2990
-
(1998)
Blood
, vol.91
, pp. 2985-2990
-
-
Quesnel, B.1
-
20
-
-
33847052552
-
Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16)
-
Markus J., et al. Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16). Cancer Res. 67 (2007) 992-1000
-
(2007)
Cancer Res.
, vol.67
, pp. 992-1000
-
-
Markus, J.1
-
21
-
-
0035959868
-
Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15(INK4b) normally associated with differentiation
-
Schmidt M., Koller R., Haviernik P., Bies J., Maciag K., and Wolff L. Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15(INK4b) normally associated with differentiation. Oncogene 20 (2001) 6205-6214
-
(2001)
Oncogene
, vol.20
, pp. 6205-6214
-
-
Schmidt, M.1
Koller, R.2
Haviernik, P.3
Bies, J.4
Maciag, K.5
Wolff, L.6
-
22
-
-
2542462097
-
The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells
-
Schmidt M., Bies J., Tamura T., Ozato K., and Wolff L. The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells. Blood 103 (2004) 4142-4149
-
(2004)
Blood
, vol.103
, pp. 4142-4149
-
-
Schmidt, M.1
Bies, J.2
Tamura, T.3
Ozato, K.4
Wolff, L.5
-
23
-
-
0034661508
-
Deregulated E2F-1 blocks terminal differentiation and loss of leukemogenicity of M1 myeloblastic leukemia cells without abrogating induction of p15(INK4B) and p16(INK4A)
-
Amanullah A., Hoffman B., and Liebermann D.A. Deregulated E2F-1 blocks terminal differentiation and loss of leukemogenicity of M1 myeloblastic leukemia cells without abrogating induction of p15(INK4B) and p16(INK4A). Blood 96 (2000) 475-482
-
(2000)
Blood
, vol.96
, pp. 475-482
-
-
Amanullah, A.1
Hoffman, B.2
Liebermann, D.A.3
-
24
-
-
0034104765
-
Expression of cyclin-dependent kinase inhibitor p15INK4B during normal and leukemic myeloid differentiation
-
Teofili L., et al. Expression of cyclin-dependent kinase inhibitor p15INK4B during normal and leukemic myeloid differentiation. Exp. Hematol. 28 (2000) 519-526
-
(2000)
Exp. Hematol.
, vol.28
, pp. 519-526
-
-
Teofili, L.1
-
25
-
-
0031595991
-
Expression of p15INK4B in normal hematopoiesis
-
Teofili L., et al. Expression of p15INK4B in normal hematopoiesis. Exp. Hematol. 26 (1998) 1133-1139
-
(1998)
Exp. Hematol.
, vol.26
, pp. 1133-1139
-
-
Teofili, L.1
-
26
-
-
33644971769
-
Effects of 5-aza-2'-deoxycytidine on proliferation, differentiation and p15/INK4b regulation of human hematopoietic progenitor cells
-
Guo Y., Engelhardt M., Wider D., Abdelkarim M., and Lubbert M. Effects of 5-aza-2'-deoxycytidine on proliferation, differentiation and p15/INK4b regulation of human hematopoietic progenitor cells. Leukemia 20 (2006) 115-121
-
(2006)
Leukemia
, vol.20
, pp. 115-121
-
-
Guo, Y.1
Engelhardt, M.2
Wider, D.3
Abdelkarim, M.4
Lubbert, M.5
-
27
-
-
0033781238
-
Lineage-specific regulation of cell cycle control gene expression during haematopoietic cell differentiation
-
Furukawa Y., Kikuchi J., Nakamura M., Iwase S., Yamada H., and Matsuda M. Lineage-specific regulation of cell cycle control gene expression during haematopoietic cell differentiation. Br. J. Haematol. 110 (2000) 663-673
-
(2000)
Br. J. Haematol.
, vol.110
, pp. 663-673
-
-
Furukawa, Y.1
Kikuchi, J.2
Nakamura, M.3
Iwase, S.4
Yamada, H.5
Matsuda, M.6
-
28
-
-
0033568578
-
Involvement of the retinoblastoma protein in monocytic and neutrophilic lineage commitment of human bone marrow progenitor cells
-
Bergh G., Ehinger M., Olsson I., Jacobsen S.E., and Gullberg U. Involvement of the retinoblastoma protein in monocytic and neutrophilic lineage commitment of human bone marrow progenitor cells. Blood 94 (1999) 1971-1978
-
(1999)
Blood
, vol.94
, pp. 1971-1978
-
-
Bergh, G.1
Ehinger, M.2
Olsson, I.3
Jacobsen, S.E.4
Gullberg, U.5
-
29
-
-
0037456990
-
Consistent inactivation of p19(Arf) but not p15(Ink4b) in murine myeloid cells transformed in vivo by deregulated c-Myc
-
Haviernik P., Schmidt M., Hu X., and Wolff L. Consistent inactivation of p19(Arf) but not p15(Ink4b) in murine myeloid cells transformed in vivo by deregulated c-Myc. Oncogene 22 (2003) 1600-1610
-
(2003)
Oncogene
, vol.22
, pp. 1600-1610
-
-
Haviernik, P.1
Schmidt, M.2
Hu, X.3
Wolff, L.4
-
30
-
-
33847049430
-
Loss of the tumor suppressor p15Ink4b enhances myeloid progenitor formation from common myeloid progenitors
-
Rosu-Myles M., Taylor B.J., and Wolff L. Loss of the tumor suppressor p15Ink4b enhances myeloid progenitor formation from common myeloid progenitors. Exp. Hematol. 35 (2007) 394-406
-
(2007)
Exp. Hematol.
, vol.35
, pp. 394-406
-
-
Rosu-Myles, M.1
Taylor, B.J.2
Wolff, L.3
-
31
-
-
0034600841
-
Limited overlapping roles of P15INK4b and P18INK4c cell cycle inhibitors in proliferation and tumorigenesis
-
Latres E., et al. Limited overlapping roles of P15INK4b and P18INK4c cell cycle inhibitors in proliferation and tumorigenesis. EMBO J. 19 (2000) 3496-3506
-
(2000)
EMBO J.
, vol.19
, pp. 3496-3506
-
-
Latres, E.1
-
32
-
-
34548131144
-
CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine
-
Raj K., et al. CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine. Leukemia 21 (2007) 1937-1944
-
(2007)
Leukemia
, vol.21
, pp. 1937-1944
-
-
Raj, K.1
-
33
-
-
0023623629
-
Effect of recombinant interferons on colony formation of blast progenitors in acute myeloblastic leukemia
-
Takanashi M., Motoji T., Oshimi K., and Mizoguchi H. Effect of recombinant interferons on colony formation of blast progenitors in acute myeloblastic leukemia. Exp. Hematol. 15 (1987) 946-951
-
(1987)
Exp. Hematol.
, vol.15
, pp. 946-951
-
-
Takanashi, M.1
Motoji, T.2
Oshimi, K.3
Mizoguchi, H.4
-
34
-
-
0021963764
-
The effects of recombinant-DNA-derived interferons on the growth of myeloid progenitor cells
-
Rigby W.F., Ball E.D., Guyre P.M., and Fanger M.W. The effects of recombinant-DNA-derived interferons on the growth of myeloid progenitor cells. Blood 65 (1985) 858-861
-
(1985)
Blood
, vol.65
, pp. 858-861
-
-
Rigby, W.F.1
Ball, E.D.2
Guyre, P.M.3
Fanger, M.W.4
-
35
-
-
33846865107
-
Continuous delivery of human type I interferons (alpha/beta) has significant activity against acute myeloid leukemia cells in vitro and in a xenograft model
-
Benjamin R., et al. Continuous delivery of human type I interferons (alpha/beta) has significant activity against acute myeloid leukemia cells in vitro and in a xenograft model. Blood 109 (2007) 244-1247
-
(2007)
Blood
, vol.109
, pp. 244-1247
-
-
Benjamin, R.1
-
36
-
-
0742272101
-
A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15Ink4b in myeloid cells in vivo
-
Wolff L., et al. A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15Ink4b in myeloid cells in vivo. Blood Cells Mol. Diseases 32 (2004) 226-231
-
(2004)
Blood Cells Mol. Diseases
, vol.32
, pp. 226-231
-
-
Wolff, L.1
-
37
-
-
0037383148
-
A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms
-
Wolff L., Koller R., Hu X., and Anver M.R. A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms. J. Virol. 77 (2003) 4965-4971
-
(2003)
J. Virol.
, vol.77
, pp. 4965-4971
-
-
Wolff, L.1
Koller, R.2
Hu, X.3
Anver, M.R.4
|