Exploring the neuroleptic substituent in octoclothepin: Potential ligands for positron emission tomography with subnanomolar affinity for α1-adrenoceptors
The Anatomy and Function of Noradrenaline in the Mammalian Brain
Oxford University Press: New York,; Chapter 1
Holets, V. R. The Anatomy and Function of Noradrenaline in the Mammalian Brain. In The Pharmacology of Noradrenaline in the Central Nervous System; Heal, D. J.; Marsden, C. A., Eds.; Oxford University Press: New York, 1990; Chapter 1, pp 1 - 40.
Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
Arnt, J.; Skaarsfeldt, T. Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence Neuropsychopharmacology 1998, 18, 63-101
Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics
Olsen, C. K.; Brennum, L. T.; Kreilgaard, M. Using pharmacokinetic- pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics Eur. J. Pharmacol. 2008, 584, 318-327
Clozapine and prazosin slow the rhythm of head movements during focused stereotypy induced by d -amphetamine in rats
Fowler, S. C.; Pinkston, J. W.; Vorontsova, E. Clozapine and prazosin slow the rhythm of head movements during focused stereotypy induced by d -amphetamine in rats Psychopharmacology 2007, 192, 219-230
1-adrenoceptor antagonists derived from the antipsychotic sertindole. Carbon-11 labelling and PET examination of brain uptake in the cynomolgus monkey
1- adrenoceptor antagonists derived from the antipsychotic sertindole. Carbon-11 labelling and PET examination of brain uptake in the cynomolgus monkey Nucl. Med. Biol. 2003, 31, 327-336
Presented at Frontiers in CNS and Oncology Medicinal Chemistry, Siena, Italy, October 7-9,; Poster P67
1-Adrenoceptor Selective Sertindole Analogs Suitable for Evaluation as PET-Ligands. Presented at Frontiers in CNS and Oncology Medicinal Chemistry, Siena, Italy, October 7-9, 2007; Poster P67.
Presented at the 17th International Symposium on Radiopharmaceutical Sciences, Aachen, Germany, April 30-May 4,; Poster P265
11C]Lu AA27122 as Potential PET Radioligand for Brain Imaging. Presented at the 17th International Symposium on Radiopharmaceutical Sciences, Aachen, Germany, April 30-May 4, 2007; Poster P265.
Conformational analysis and structural comparisons of (1 R,3 S)-(+)- and (1 S,3 R)-(-)-tefludazine, (S)-(+)- and (R)-(-)-octoclothepin, and (+)-dexclamol in relation to dopamine receptor antagonism and amine-uptake inhibition
Liljefors, T.; Bøgesø, K. P. Conformational analysis and structural comparisons of (1 R,3 S)-(+)- and (1 S,3 R)-(-)-tefludazine, (S)-(+)- and (R)-(-)-octoclothepin, and (+)-dexclamol in relation to dopamine receptor antagonism and amine-uptake inhibition J. Med. Chem. 1988, 31, 306-312
Octoclothepin enantiomers. A reinvestigation of their biochemical and pharmacological activity in relation to a new receptor-interaction model for dopamine D-2 receptor antagonists
Bøgesø, K. P.; Liljefors, T.; Arnt, J.; Hyttel, J.; Pedersen, H. Octoclothepin enantiomers. A reinvestigation of their biochemical and pharmacological activity in relation to a new receptor-interaction model for dopamine D-2 receptor antagonists J. Med. Chem. 1991, 34, 2023-2030
A structure-activity study of four dopamine D-1 and D-2 receptor antagonists, representing the phenylindan, -indene, and -indole structural classes of compounds
Palm, J.; Bøgesø, K. P.; Liljefors, T. A structure-activity study of four dopamine D-1 and D-2 receptor antagonists, representing the phenylindan, -indene, and -indole structural classes of compounds J. Med. Chem. 1993, 36, 2878-2885
Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)- tricyclohexylphosphine complexes
Ishiyama, T.; Ishida, K.; Miyaura, N. Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)-tricyclohexylphosphine complexes Tetrahedron 2001, 57, 9813-9816
Neurotropic and psychotropic agents. VIII. 10-(4-Methylpiperazino)-10,11- dihydrodibenzo[ b, f ]thiepine and analogs. A new group of neuroleptics
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Neurotropic and psychotropic agents. XIX. 8-Halo derivatives of 10-(4-methyl-1-piperazinyl)-10,11-dihydrodibenzo[ b, f ]thiepine and related substances
Jilek, J. O.; Metysova, J.; Pomykazek, J.; Protiva, M. Neurotropic and psychotropic agents. XIX. 8-Halo derivatives of 10-(4-methyl-1-piperazinyl)-10, 11-dihydrodibenzo[ b, f ]thiepine and related substances Collect. Czech. Chem. Commun. 1968, 33, 1831-1845
Fast microwave-assisted preparation of aryl and vinyl nitriles and the corresponding tetrazoles from organo-halides
Alterman, M.; Hallberg, A. Fast microwave-assisted preparation of aryl and vinyl nitriles and the corresponding tetrazoles from organo-halides J. Org. Chem. 2000, 65, 7984-7989
Palladium-catalyzed arylation of malonates and cyano esters using sterically hindered trialkyl- and ferrocenyldialkylphosphine ligands
Beare, N. A.; Hartwig, J. F. Palladium-catalyzed arylation of malonates and cyano esters using sterically hindered trialkyl- and ferrocenyldialkylphosphine ligands J. Org. Chem. 2002, 67, 541-555
Ph-metric log- P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values
Slater, B.; McCormack, A.; Avdeef, A.; Comer, J. Ph-metric log? P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values J. Pharm. Sci. 1994, 83, 1280-1283
Evaluation of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-methyl-2-(S)- pyrrolidinylmethoxy)pyridine and its analogues as PET radioligands for imaging nicotinic acetylcholine receptors
Brown, L. V.; Chefer, S.; Pavlova, O.; Vaupel, D. B.; Koren, A. O.; Kimes, A. S.; Horti, A. G.; Mukhin, A. G. Evaluation of 5-(2-(4-pyridinyl)vinyl) -6-chloro-3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine and its analogues as PET radioligands for imaging nicotinic acetylcholine receptors J. Neurochem. 2004, 91, 600-612
